Welcome to Sequence Card of Peptide
Details of CPPsite entry with Sequence RRIRPRPPRLPRPRPRPLPFPRPG |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | RRIRPRPPRLPRPRPRPLPFPRPG |
| CPPsite ID | 2257, 2258, 2259, 2447, 1321, |
| PEPTIDE NAME | Bac-ELP43, Bac-ELP63, Bac-ELP122, p21-ELP1-Bac, Bac1-24 |
| CHIRALITY | L, L, L, L, L |
| LINEAR/CYCLIC | Linear, Linear, Linear, Linear, Linear |
| SOURCE | Synthetic, Synthetic, Synthetic, Synthetic, Protein derived |
| CATEGORY | Cationic, Cationic, Cationic, NA, Antimicrobial |
| SUB CELLULAR LOCALIZATION | Nucleus, Nucleus, Nucleus, Nucleus, Cytoplasm and nucleus |
| N-TERMINAL MODIFICATION | Free, Free, Free, Conjugated with p21-ELP1, Conjugation with fluorescein |
| C-TERMINAL MODIFICATION | Free, Free, Free, Free, Free |
| CHEMICAL MODIFICATION | NA, NA, NA, NA, NA |
| UPTAKE EFFICIENCY | Lower efficiency, Higher efficiency, Higher efficiency, Higher uptake efficiency, Lower than Tat (49-57) |
| PROPOSED UPTAKE MECHANISM | NA, NA, NA, NA, Unknown |
| INVITRO/INVIVO | In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro |
| CELL LINE | S2013, S2013, S2013, S2013, Mia PaCa-2 and Panc-1, RAW 264.7 |
| In VIVO MODEL | Female athymic nude mice (Ncr-nu/nu), Female athymic nude mice (Ncr-nu/nu), Female athymic nude mice (Ncr-nu/nu), Female athymic nude mice (Ncr-nu/nu), NA |
| CARGO | Peptide [ELP (Elastin like peptide sequence), Fluorophore (Alexa-Fluor)], Peptide [ELP (Elastin like peptide sequence), Fluorophore (Alexa-Fluor)], Peptide [ELP (Elastin like peptide sequence), Fluorophore (Alexa-Fluor)], Peptide (p21-ELP), Fluorophore (fluorescein) |
| PMID | 24866938, 24866938, 24866938, 24680816, 12450378 |
| PATENT | Unknown, Unknown, Unknown, Unknown, Unknown |
| Tertiary Structure (Technique) | Not Predicted), Not Predicted), Not Predicted), 2447 (PEPstrMOD), 1321 (PEPstrMOD), |