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Details of CPPsite entry with Sequence RRWWRRWRR
Primary information
PEPTIDE SEQUENCERRWWRRWRR
CPPsite ID 2320, 2783,
PEPTIDE NAMER6W3, RW-9
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Synthetic
CATEGORYCationic, Cationic
SUB CELLULAR LOCALIZATIONCytoplasm, NA
N-TERMINAL MODIFICATIONBiotinylation, NA
C-TERMINAL MODIFICATIONAmidation, Amidation
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYHigher than R9, Tat and R6L4, NA
PROPOSED UPTAKE MECHANISMSelectively driven by the presence of GAGs and is likely distinct from macropinocytosis and general endocytosis, NA
INVITRO/INVIVOIn vitro, In vitro
CELL LINECHO-K1 (WT) and xylose transferase- or GAG-deficient CHO-pgsA745 cells (GAGneg), CHO-K1
In VIVO MODELNA, NA
CARGOBiotin-gly4, Fluorophore (Alexa 488)
PMID25112713, 23524021
PATENTUnknown, Unknown
Tertiary Structure
(Technique)		2320 (PEPstrMOD), 2783 (PEPstrMOD),