Browse Epitopes |
This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein.
This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header.
The last three column present the field related to HLA prediction using CTLpred and nHLApred The second last tells us the HLA alleles to which peptide is binding. The last column counts the number of HLA alleles for that peptide.
Total number of predicted 9mer peptides are 279773 (corresponding to browse type ctl)
| ID | gene ID | Protein Detail | Position | Sequence (9mer) | MHC class I Alleles | MHC class I alleles (count) | HLA Alleles | HLA alleles (count) |
|---|---|---|---|---|---|---|---|---|
| SEC139820 | 449065993 | YP 007433076.1 hypothe | 75 | SMSTLNARI | HLA-A*0201,HLA-A2.1,HLA-A3,HLA-B*2702,HLA-B*5102,MHC-Db revised,MHC-Kk | 7 | HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 | 9 |
| SEC139822 | 449065993 | YP 007433076.1 hypothe | 77 | STLNARIAI | HLA-B14,HLA-B*5102,HLA-B*5103,HLA-B*5801,MHC-Db,MHC-Db revised,MHC-Kd,MHC-Kk | 8 | HLA-A*1101,HLA-A3,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01,HLA-A*6801 | 12 |
| SEC139841 | 449065993 | YP 007433076.1 hypothe | 96 | VTSPLAITM | HLA-A1,HLA-B*3501,HLA-B*51,HLA-B*5301,HLA-B*5801 | 5 | HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 | 9 |
| SEC139860 | 449065993 | YP 007433076.1 hypothe | 115 | NYADAMEAL | HLA-A24,HLA-B*3801,HLA-B*3901,HLA-B*3902,HLA-Cw*0401,HLA-Cw*0702,MHC-Kd | 7 | HLA-A24,HLA-A*2402,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 | 11 |
| SEC139878 | 449065993 | YP 007433076.1 hypothe | 133 | HLVAWMKAV | HLA-A*0201,HLA-A*0205,HLA-A2,HLA-A2.1,HLA-A3,HLA-B*0702,HLA-B62 | 7 | HLA-A*0201,HLA-A*0301,HLA-A2.1,HLA-B*5301,HLA-B*5401,HLA-B*0702,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 | 15 |
| SEC139882 | 449065993 | YP 007433076.1 hypothe | 137 | WMKAVVYGA | HLA-A3,HLA-B*51,HLA-B*5301,HLA-B*5401 | 4 | HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01,HLA-A*3301 | 10 |
| SEC139917 | 449065993 | YP 007433076.1 hypothe | 172 | GVAHGVAAA | HLA-A*0205,HLA-A68.1 | 2 | HLA-A*0301,HLA-B*5301,HLA-B*5401,HLA-B*51,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01,HLA-A*3301 | 14 |
| SEC139928 | 449065993 | YP 007433076.1 hypothe | 183 | ALFTEAERR | HLA-A*1101,HLA-A20 Cattle,HLA-A2.1,HLA-A3,HLA-A*3101,HLA-A*3302,HLA-A68.1,HLA-B*2705 | 8 | HLA-A2,HLA-A3,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 | 11 |
| SEC139949 | 449065993 | YP 007433076.1 hypothe | 204 | CARAIAWYL | HLA-B*3501,HLA-B*3701,HLA-B*5101,HLA-B*5102,HLA-B*5103,HLA-B*5801,HLA-B60,HLA-B7,HLA-B8,HLA-Cw*0602,MHC-Db revised | 11 | HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,HLA-B35,Mamu-A*01 | 10 |
| SEC139950 | 449065993 | YP 007433076.1 hypothe | 205 | ARAIAWYLA | HLA-B*2702,HLA-B*2705 | 2 | HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 | 9 |
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