ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3465 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
98 | 60 | 38 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3466 | GUAAUUCAACGCUAGAA CAUUAAGUUGCGAUCUU |
100 | 40 | 60 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3467 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3468 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 67 | 30 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3469 | CCCUCAUCCACUGUGUGCA GGGAGUAGGUGACACACGU |
100 | 10 | 90 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3470 | CCCUCAUCUACUGUGUGCAU GGGAGUAGAUGACACACGUA |
75 | 40 | 35 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3471 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
60 | 8 | 52 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3472 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3473 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3474 | GGAAGUCUGUGCCCUUGUGU CCUUCAGACACGGGAACACA |
76 | 45 | 31 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3475 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
98 | 28 | 70 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3476 | GUAAUUCAACGCUAGAA CAUUAAGUUGCGAUCUU |
100 | 40 | 60 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3477 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3478 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 30 | 67 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3479 | CCCUCAUCCACUGUGUGCA GGGAGUAGGUGACACACGU |
100 | 10 | 90 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3480 | CCCUCAUCUACUGUGUGCAU GGGAGUAGAUGACACACGUA |
75 | 40 | 35 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3481 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
60 | 8 | 52 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3482 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3483 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3484 | GGAAGUCUGUGCCCUUGUGU CCUUCAGACACGGGAACACA |
76 | 45 | 31 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |