ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0987 | CAGCAGCAGCAGUAGCAGCAG GUCGUCGUCGUCAUCGUCGUC |
75 | 20 | 55 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0988 | CAGCAGCAGCAGCAGUAGCAG GUCGUCGUCGUCGUCAUCGUC |
60 | 23 | 37 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0989 | CAGCAGCAGCAGUAGUAGCAG GUCGUCGUCGUCAUCAUCGUC |
78 | 20 | 58 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0990 | UAGCAGCAGCAGCAGCAGUAG AUCGUCGUCGUCGUCGUCAUC |
60 | 45 | 15 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |