ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3158 | GCCUGGAUCUGUGCUUGCC CGGACCUAGACACGAACGG |
80 | 45 | 35 | TP63 | Ectrodactily-ectodermal dysplasia and cleft lip/palate (EEC) | c.727C>T, p.Arg243Trp | rs12190883 | ||
aspsirna3159 | CUUUGAGGCCUGGAUCUGU GAAACUCCGGACCUAGACA |
67 | 0 | 67 | TP63 | Ectrodactily-ectodermal dysplasia and cleft lip/palate (EEC) | c.727C>T, p.Arg243Trp | rs12190883 | ||
aspsirna3160 | GCCUGGAUCUGUGCUUGCC CGGACCUAGACACGAACGG |
81 | 45 | 36 | TP63 | Ectrodactily-ectodermal dysplasia and cleft lip/palate (EEC) | c.727C>T, p.Arg243Trp | rs12190883 | ||
aspsirna3161 | CUUUGAGGCCUGGAUCUGU GAAACUCCGGACCUAGACA |
70 | 0 | 70 | TP63 | Ectrodactily-ectodermal dysplasia and cleft lip/palate (EEC) | c.727C>T, p.Arg243Trp | rs12190883 |