ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1015 | CUGAACCCCCUCAAAAGCC GACUUGGGGGAGUUUUCGG |
75 | 64 | 11 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 | ||
aspsirna1016 | CCUCAAAAGCCAAAAAAUG GGAGUUUUCGGUUUUUUAC |
78 | 44 | 34 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 | ||
aspsirna1017 | CCCCAAAAGCCAAAAAAU GGGGUUUUCGGUUUUUUA |
80 | 40 | 40 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |