ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3561 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
90 | 10 | 80 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna3562 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | 20 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna3563 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
96 | 23 | 73 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna3568 | GACAAAGAUGCUGUGGCCGAU CUGUUUCUACGACACCGGCUA |
87 | 20 | 67 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C (p.Gly94Ala) | rs12191243 |