Total number of Results for Dominant dystrophic epidermolysis bullosa(DDEB) are 66
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0274 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA		 78 23 55 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0275 GUGCCA---GCUGUGGUCGGGC
CACGGU---CGACACCAGCCCG		 76 35 41 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0276 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC		 67 39 28 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0277 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC		 66 20 46 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0278 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC		 58 38 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0279 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG		 60 43 17 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0280 CUGGUGUGCCA---GCUGUGGU
GACCACACGGU---CGACACCA		 80 45 35 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0281 CCUGGUGUGCCA---GCUGUGG
GGACCACACGGU---CGACACC		 70 40 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0282 CCCUGGUGUGCCA---GCUGUG
GGGACCACACGGU---CGACAC		 90 32 58 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0283 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA		 24 0 24 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0284 AGCCCUGGUGUGCCA---GCUG
UCGGGACCACACGGU---CGAC		 90 43 47 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0285 GAGCCCUGGUGUGCCA---GCU
CUCGGGACCACACGGU---CGA		 88 21 67 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0286 GGAGCCCUGGUGUGCCA---GC
CCUCGGGACCACACGGU---CG		 30 18 12 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0287 CCA---GCUGUGGUCGGGCUCC
GGU---CGACACCAGCCCGAGG		 78 42 36 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0288 GCCA---GCUGUGGUCGGGCUC
CGGU---CGACACCAGCCCGAG		 67 40 27 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0289 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA		 NA 70 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0290 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC		 NA 0 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0291 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG		 95 38 57 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0292 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC		 80 38 42 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0293 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC		 90 34 56 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0294 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA		 90 83 7 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0295 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA		 77 25 52 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0296 GUGCCA---GCUGUGGUCGGGC
CACGGU---CGACACCAGCCCG		 78 20 58 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0297 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC		 30 20 10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0298 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC		 29 10 19 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0299 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC		 19 10 9 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0300 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG		 23 20 3 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0301 CUGGUGUGCCA---GCUGUGGU
GACCACACGGU---CGACACCA		 45 25 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0302 CCUGGUGUGCCA---GCUGUGG
GGACCACACGGU---CGACACC		 70 40 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0303 CCCUGGUGUGCCA---GCUGUG
GGGACCACACGGU---CGACAC		 90 32 58 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0304 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA		 24 0 24 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0305 AGCCCUGGUGUGCCA---GCUG
UCGGGACCACACGGU---CGAC		 90 NA NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0306 GAGCCCUGGUGUGCCA---GCU
CUCGGGACCACACGGU---CGA		 88 NA NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0307 GGAGCCCUGGUGUGCCA---GC
CCUCGGGACCACACGGU---CG		 30 18 12 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0308 CCA---GCUGUGGUCGGGCUCC
GGU---CGACACCAGCCCGAGG		 23 42 -19 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0309 GCCA---GCUGUGGUCGGGCUC
CGGU---CGACACCAGCCCGAG		 NA 40 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0310 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA		 NA 70 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0311 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC		 NA 0 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0312 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG		 95 38 57 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0313 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC		 80 38 42 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0314 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC		 90 34 56 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0315 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA		 90 83 7 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
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aspsirna0316 GGAAAGCCUGGUAUUCCCA
CCUUUCGGACCAUAAGGGU		 80 28 52 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0317 GAAAGCCUGGUAUUCCCAG
CUUUCGGACCAUAAGGGUC		 58 33 25 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0318 AAAGCCUGGUAUUCCCAGG
UUUCGGACCAUAAGGGUCC		 10 5 5 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0319 AAGCCUGGUAUUCCCAGGC
UUCGGACCAUAAGGGUCCG		 30 21 9 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0320 AGCCUGGUAUUCCCAGGCU
UCGGACCAUAAGGGUCCGA		 82 15 67 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0321 GCCUGGUAUUCCCAGGCUC
CGGACCAUAAGGGUCCGAG		 50 11 39 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0322 CCUGGUAUUCCCAGGCUCC
GGACCAUAAGGGUCCGAGG		 50 20 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0323 CUGGUAUUCCCAGGCUCCC
GACCAUAAGGGUCCGAGGG		 32 32 0 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0324 UGGUAUUCCCAGGCUCCCA
ACCAUAAGGGUCCGAGGGU		 40 20 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0325 GGUAUUCCCAGGCUCCCAG
CCAUAAGGGUCCGAGGGUC		 20 10 10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0326 GUAUUCCCAGGCUCCCAGG
CAUAAGGGUCCGAGGGUCC		 23 5 18 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0327 UAUUCCCAGGCUCCCAGGC
AUAAGGGUCCGAGGGUCCG		 88 20 68 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0328 AUUCCCAGGCUCCCAGGCA
UAAGGGUCCGAGGGUCCGU		 30 10 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0329 UUCCCAGGCUCCCAGGCAG
AAGGGUCCGAGGGUCCGUC		 30 20 10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0330 UCCCAGGCUCCCAGGCAGG
AGGGUCCGAGGGUCCGUCC		 24 10 14 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0331 CCCAGGCUCCCAGGCAGGG
GGGUCCGAGGGUCCGUCCC		 92 6 86 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0332 CCAGGCUCCCAGGCAGGGC
GGUCCGAGGGUCCGUCCCG		 50 20 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0333 CAGGCUCCCAGGCAGGGCU
GUCCGAGGGUCCGUCCCGA		 75 15 60 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0334 AGGCUCCCAGGCAGGGCUG
UCCGAGGGUCCGUCCCGAC		 90 0 90 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0335 AAAGCCUGGUAUUCCCAGG
UUUCGGACCAUAAGGGUCC		 76 54 22 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0336 AAGCCUGGUAUUCCCAGGC
UUCGGACCAUAAGGGUCCG		 92 40 52 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0337 GGUAUUCCCAGGCUCCCAG
CCAUAAGGGUCCGAGGGUC		 62 3 59 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0338 UAUUCCCAGGCUCCCAGGC
AUAAGGGUCCGAGGGUCCG		 45 5 40 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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aspsirna0339 CCCAGGCUCCCAGGCAGGG
GGGUCCGAGGGUCCGUCCC		 57 67 -10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
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