Total number of Results for Dominant dystrophic epidermolysis bullosa(DDEB) are 66
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0274 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA
78 23 55 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0275 GUGCCA---GCUGUGGUCGGGC
CACGGU---CGACACCAGCCCG
76 35 41 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0276 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC
67 39 28 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0277 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC
66 20 46 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0278 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC
58 38 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0279 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG
60 43 17 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0280 CUGGUGUGCCA---GCUGUGGU
GACCACACGGU---CGACACCA
80 45 35 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0281 CCUGGUGUGCCA---GCUGUGG
GGACCACACGGU---CGACACC
70 40 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0282 CCCUGGUGUGCCA---GCUGUG
GGGACCACACGGU---CGACAC
90 32 58 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0283 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA
24 0 24 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0284 AGCCCUGGUGUGCCA---GCUG
UCGGGACCACACGGU---CGAC
90 43 47 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0285 GAGCCCUGGUGUGCCA---GCU
CUCGGGACCACACGGU---CGA
88 21 67 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0286 GGAGCCCUGGUGUGCCA---GC
CCUCGGGACCACACGGU---CG
30 18 12 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0287 CCA---GCUGUGGUCGGGCUCC
GGU---CGACACCAGCCCGAGG
78 42 36 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0288 GCCA---GCUGUGGUCGGGCUC
CGGU---CGACACCAGCCCGAG
67 40 27 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0289 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA
NA 70 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0290 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC
NA 0 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0291 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG
95 38 57 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0292 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC
80 38 42 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0293 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC
90 34 56 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0294 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA
90 83 7 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0295 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA
77 25 52 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0296 GUGCCA---GCUGUGGUCGGGC
CACGGU---CGACACCAGCCCG
78 20 58 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0297 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC
30 20 10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0298 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC
29 10 19 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0299 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC
19 10 9 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0300 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG
23 20 3 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0301 CUGGUGUGCCA---GCUGUGGU
GACCACACGGU---CGACACCA
45 25 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0302 CCUGGUGUGCCA---GCUGUGG
GGACCACACGGU---CGACACC
70 40 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0303 CCCUGGUGUGCCA---GCUGUG
GGGACCACACGGU---CGACAC
90 32 58 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0304 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA
24 0 24 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0305 AGCCCUGGUGUGCCA---GCUG
UCGGGACCACACGGU---CGAC
90 NA NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0306 GAGCCCUGGUGUGCCA---GCU
CUCGGGACCACACGGU---CGA
88 NA NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0307 GGAGCCCUGGUGUGCCA---GC
CCUCGGGACCACACGGU---CG
30 18 12 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0308 CCA---GCUGUGGUCGGGCUCC
GGU---CGACACCAGCCCGAGG
23 42 -19 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0309 GCCA---GCUGUGGUCGGGCUC
CGGU---CGACACCAGCCCGAG
NA 40 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0310 UGCCA---GCUGUGGUCGGGCU
ACGGU---CGACACCAGCCCGA
NA 70 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0311 GUGUGCCA---GCUGUGGUCGG
CACACGGU---CGACACCAGCC
NA 0 NA COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0312 UGGUGUGCCA---GCUGUGGUC
ACCACACGGU---CGACACCAG
95 38 57 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0313 GGUGUGCCA---GCUGUGGUCG
CCACACGGU---CGACACCAGC
80 38 42 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0314 UGUGCCA---GCUGUGGUCGGG
ACACGGU---CGACACCAGCCC
90 34 56 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0315 GCCCUGGUGUGCCA---GCUGU
CGGGACCACACGGU---CGACA
90 83 7 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6752G>A,p.Gly2251Glu rs12191283
22336946
aspsirna0316 GGAAAGCCUGGUAUUCCCA
CCUUUCGGACCAUAAGGGU
80 28 52 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0317 GAAAGCCUGGUAUUCCCAG
CUUUCGGACCAUAAGGGUC
58 33 25 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0318 AAAGCCUGGUAUUCCCAGG
UUUCGGACCAUAAGGGUCC
10 5 5 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0319 AAGCCUGGUAUUCCCAGGC
UUCGGACCAUAAGGGUCCG
30 21 9 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0320 AGCCUGGUAUUCCCAGGCU
UCGGACCAUAAGGGUCCGA
82 15 67 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0321 GCCUGGUAUUCCCAGGCUC
CGGACCAUAAGGGUCCGAG
50 11 39 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0322 CCUGGUAUUCCCAGGCUCC
GGACCAUAAGGGUCCGAGG
50 20 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0323 CUGGUAUUCCCAGGCUCCC
GACCAUAAGGGUCCGAGGG
32 32 0 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0324 UGGUAUUCCCAGGCUCCCA
ACCAUAAGGGUCCGAGGGU
40 20 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0325 GGUAUUCCCAGGCUCCCAG
CCAUAAGGGUCCGAGGGUC
20 10 10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0326 GUAUUCCCAGGCUCCCAGG
CAUAAGGGUCCGAGGGUCC
23 5 18 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0327 UAUUCCCAGGCUCCCAGGC
AUAAGGGUCCGAGGGUCCG
88 20 68 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0328 AUUCCCAGGCUCCCAGGCA
UAAGGGUCCGAGGGUCCGU
30 10 20 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0329 UUCCCAGGCUCCCAGGCAG
AAGGGUCCGAGGGUCCGUC
30 20 10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0330 UCCCAGGCUCCCAGGCAGG
AGGGUCCGAGGGUCCGUCC
24 10 14 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0331 CCCAGGCUCCCAGGCAGGG
GGGUCCGAGGGUCCGUCCC
92 6 86 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0332 CCAGGCUCCCAGGCAGGGC
GGUCCGAGGGUCCGUCCCG
50 20 30 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0333 CAGGCUCCCAGGCAGGGCU
GUCCGAGGGUCCGUCCCGA
75 15 60 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0334 AGGCUCCCAGGCAGGGCUG
UCCGAGGGUCCGUCCCGAC
90 0 90 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0335 AAAGCCUGGUAUUCCCAGG
UUUCGGACCAUAAGGGUCC
76 54 22 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0336 AAGCCUGGUAUUCCCAGGC
UUCGGACCAUAAGGGUCCG
92 40 52 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0337 GGUAUUCCCAGGCUCCCAG
CCAUAAGGGUCCGAGGGUC
62 3 59 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0338 UAUUCCCAGGCUCCCAGGC
AUAAGGGUCCGAGGGUCCG
45 5 40 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946
aspsirna0339 CCCAGGCUCCCAGGCAGGG
GGGUCCGAGGGUCCGUCCC
57 67 -10 COL7A1 Dominant dystrophic epidermolysis bullosa(DDEB) c.6127G>A,p.Gly2043Arg rs12191283
22336946