ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0447 | CUCAACAAUAAGUUUGCCC GAGUUGUUAUUCAAACGGG |
0 | 10 | -10 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0448 | UCAACAAUAAGUUUGCCCC AGUUGUUAUUCAAACGGGG |
0 | 40 | -40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0449 | CAACAAUAAGUUUGCCCCC GUUGUUAUUCAAACGGGGG |
0 | 60 | -60 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0450 | AACAAUAAGUUUGCCCCCU UUGUUAUUCAAACGGGGGA |
0 | 30 | -30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0451 | ACAAUAAGUUUGCCCCCUU UGUUAUUCAAACGGGGGAA |
62 | 15 | 47 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0452 | CAAUAAGUUUGCCCCCUUC GUUAUUCAAACGGGGGAAG |
70 | 42 | 28 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0453 | AAUAAGUUUGCCCCCUUCA UUAUUCAAACGGGGGAAGU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0454 | AUAAGUUUGCCCCCUUCAU UAUUCAAACGGGGGAAGUA |
90 | 18 | 72 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0455 | UAAGUUUGCCCCCUUCAUC AUUCAAACGGGGGAAGUAG |
20 | 0 | 20 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0456 | AAGUUUGCCCCCUUCAUCG UUCAAACGGGGGAAGUAGC |
30 | 0 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0457 | AGUUUGCCCCCUUCAUCGA UCAAACGGGGGAAGUAGCU |
79 | 30 | 49 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0458 | GUUUGCCCCCUUCAUCGAC CAAACGGGGGAAGUAGCUG |
90 | 35 | 55 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0459 | UUUGCCCCCUUCAUCGACA AAACGGGGGAAGUAGCUGU |
30 | 0 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0460 | UUGCCCCCUUCAUCGACAA AACGGGGGAAGUAGCUGUU |
40 | 10 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0461 | UGCCCCCUUCAUCGACAAG ACGGGGGAAGUAGCUGUUC |
12 | 20 | -8 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0462 | GCCCCCUUCAUCGACAAGG CGGGGGAAGUAGCUGUUCC |
35 | 12 | 23 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0463 | CCCCCUUCAUCGACAAGGU GGGGGAAGUAGCUGUUCCA |
60 | 35 | 25 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0464 | CCCCUUCAUCGACAAGGUG GGGGAAGUAGCUGUUCCAC |
62 | 35 | 27 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0465 | CCCUUCAUCGACAAGGUGC GGGAAGUAGCUGUUCCACG |
41 | 45 | -4 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0466 | GUUCCUGGAGCAGCAGAAG CAAGGACCUCGUCGUCUUC |
45 | 0 | 45 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0467 | UUCCUGGAGCAGCAGAAGA AAGGACCUCGUCGUCUUCU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0468 | UCCUGGAGCAGCAGAAGAA AGGACCUCGUCGUCUUCUU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0469 | CCUGGAGCAGCAGAAGAAG GGACCUCGUCGUCUUCUUC |
34 | 0 | 34 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0470 | CUGGAGCAGCAGAAGAAGG GACCUCGUCGUCUUCUUCC |
42 | 0 | 42 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0471 | UGGAGCAGCAGAAGAAGGU ACCUCGUCGUCUUCUUCCA |
50 | 0 | 50 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0472 | GGAGCAGCAGAAGAAGGUU CCUCGUCGUCUUCUUCCAA |
70 | 0 | 70 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0473 | GAGCAGCAGAAGAAGGUUC CUCGUCGUCUUCUUCCAAG |
73 | 0 | 73 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0474 | AGCAGCAGAAGAAGGUUCU UCGUCGUCUUCUUCCAAGA |
10 | 0 | 10 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0475 | GCAGCAGAAGAAGGUUCUG CGUCGUCUUCUUCCAAGAC |
10 | 0 | 10 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0476 | CAGCAGAAGAAGGUUCUGG GUCGUCUUCUUCCAAGACC |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0477 | AGCAGAAGAAGGUUCUGGA UCGUCUUCUUCCAAGACCU |
42 | 0 | 42 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0478 | GCAGAAGAAGGUUCUGGAC CGUCUUCUUCCAAGACCUG |
30 | 0 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0479 | CAGAAGAAGGUUCUGGACA GUCUUCUUCCAAGACCUGU |
25 | 0 | 25 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0480 | AGAAGAAGGUUCUGGACAC UCUUCUUCCAAGACCUGUG |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0481 | GAAGAAGGUUCUGGACACC CUUCUUCCAAGACCUGUGG |
8 | 10 | -2 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0482 | AAGAAGGUUCUGGACACCA UUCUUCCAAGACCUGUGGU |
25 | 0 | 25 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0483 | AGAAGGUUCUGGACACCAA UCUUCCAAGACCUGUGGUU |
45 | 0 | 45 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0484 | GAAGGUUCUGGACACCAAG CUUCCAAGACCUGUGGUUC |
19 | 10 | 9 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0485 | CUCAACAAUAAGUUUGCCC GAGUUGUUAUUCAAACGGG |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0486 | UCAACAAUAAGUUUGCCCC AGUUGUUAUUCAAACGGGG |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0487 | CAACAAUAAGUUUGCCCCC GUUGUUAUUCAAACGGGGG |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0488 | AACAAUAAGUUUGCCCCCU UUGUUAUUCAAACGGGGGA |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0489 | ACAAUAAGUUUGCCCCCUU UGUUAUUCAAACGGGGGAA |
62 | 15 | 47 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0490 | CAAUAAGUUUGCCCCCUUC GUUAUUCAAACGGGGGAAG |
70 | 42 | 28 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0491 | AAUAAGUUUGCCCCCUUCA UUAUUCAAACGGGGGAAGU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0492 | AUAAGUUUGCCCCCUUCAU UAUUCAAACGGGGGAAGUA |
90 | 18 | 72 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0493 | UAAGUUUGCCCCCUUCAUC AUUCAAACGGGGGAAGUAG |
20 | 0 | 20 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0494 | AAGUUUGCCCCCUUCAUCG UUCAAACGGGGGAAGUAGC |
30 | 0 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0495 | AGUUUGCCCCCUUCAUCGA UCAAACGGGGGAAGUAGCU |
79 | 30 | 49 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0496 | GUUUGCCCCCUUCAUCGAC CAAACGGGGGAAGUAGCUG |
90 | 35 | 55 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0497 | UUUGCCCCCUUCAUCGACA AAACGGGGGAAGUAGCUGU |
30 | 0 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0498 | UUGCCCCCUUCAUCGACAA AACGGGGGAAGUAGCUGUU |
40 | 10 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0499 | UGCCCCCUUCAUCGACAAG ACGGGGGAAGUAGCUGUUC |
12 | 0 | 12 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0500 | GCCCCCUUCAUCGACAAGG CGGGGGAAGUAGCUGUUCC |
35 | 12 | 23 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0501 | CCCCCUUCAUCGACAAGGU GGGGGAAGUAGCUGUUCCA |
60 | 35 | 25 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0502 | CCCCUUCAUCGACAAGGUG GGGGAAGUAGCUGUUCCAC |
62 | 35 | 27 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0503 | CCCUUCAUCGACAAGGUGC GGGAAGUAGCUGUUCCACG |
41 | 22 | 19 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ||
aspsirna0504 | GUUCCUGGAGCAGCAGAAG CAAGGACCUCGUCGUCUUC |
45 | 0 | 45 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0505 | UUCCUGGAGCAGCAGAAGA AAGGACCUCGUCGUCUUCU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0506 | UCCUGGAGCAGCAGAAGAA AGGACCUCGUCGUCUUCUU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0507 | CCUGGAGCAGCAGAAGAAG GGACCUCGUCGUCUUCUUC |
34 | 0 | 34 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0508 | CUGGAGCAGCAGAAGAAGG GACCUCGUCGUCUUCUUCC |
42 | 0 | 42 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0509 | UGGAGCAGCAGAAGAAGGU ACCUCGUCGUCUUCUUCCA |
50 | 0 | 50 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0510 | GGAGCAGCAGAAGAAGGUU CCUCGUCGUCUUCUUCCAA |
70 | 0 | 70 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0511 | GAGCAGCAGAAGAAGGUUC CUCGUCGUCUUCUUCCAAG |
73 | 0 | 73 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0512 | AGCAGCAGAAGAAGGUUCU UCGUCGUCUUCUUCCAAGA |
10 | 0 | 10 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0513 | GCAGCAGAAGAAGGUUCUG CGUCGUCUUCUUCCAAGAC |
10 | 0 | 10 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0514 | CAGCAGAAGAAGGUUCUGG GUCGUCUUCUUCCAAGACC |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0515 | AGCAGAAGAAGGUUCUGGA UCGUCUUCUUCCAAGACCU |
42 | 0 | 42 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0516 | GCAGAAGAAGGUUCUGGAC CGUCUUCUUCCAAGACCUG |
30 | 0 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0517 | CAGAAGAAGGUUCUGGACA GUCUUCUUCCAAGACCUGU |
25 | 0 | 25 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0518 | AGAAGAAGGUUCUGGACAC UCUUCUUCCAAGACCUGUG |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0519 | GAAGAAGGUUCUGGACACC CUUCUUCCAAGACCUGUGG |
8 | 10 | -2 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0520 | AAGAAGGUUCUGGACACCA UUCUUCCAAGACCUGUGGU |
25 | 0 | 25 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0521 | AGAAGGUUCUGGACACCAA UCUUCCAAGACCUGUGGUU |
45 | 0 | 45 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ||
aspsirna0522 | GAAGGUUCUGGACACCAAG CUUCCAAGACCUGUGGUUC |
19 | 10 | 9 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 |