Total number of Results for Epidermolytic palmoplantar keratoderma (EPPK) are 76
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0576 AUGCAGGAACUCAAUUCUU
UACGUCCUUGAGUUAAGAA		 75 20 55 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0577 UGCAGGAACUCAAUUCUUG
ACGUCCUUGAGUUAAGAAC		 15 22 -7 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0578 GCAGGAACUCAAUUCUUGG
CGUCCUUGAGUUAAGAACC		 20 0 20 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0579 CAGGAACUCAAUUCUUGGC
GUCCUUGAGUUAAGAACCG		 5 0 5 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0580 AGGAACUCAAUUCUUGGCU
UCCUUGAGUUAAGAACCGA		 43 28 15 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0581 GGAACUCAAUUCUUGGCUG
CCUUGAGUUAAGAACCGAC		 30 0 30 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0582 GAACUCAAUUCUUGGCUGG
CUUGAGUUAAGAACCGACC		 28 0 28 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0583 AACUCAAUUCUUGGCUGGC
UUGAGUUAAGAACCGACCG		 10 0 10 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0584 ACUCAAUUCUUGGCUGGCC
UGAGUUAAGAACCGACCGG		 9 0 9 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0585 CUCAAUUCUUGGCUGGCCU
GAGUUAAGAACCGACCGGA		 25 0 25 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0586 UCAAUUCUUGGCUGGCCUC
AGUUAAGAACCGACCGGAG		 45 0 45 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0587 CAAUUCUUGGCUGGCCUCU
GUUAAGAACCGACCGGAGA		 20 0 20 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0588 AAUUCUUGGCUGGCCUCUU
UUAAGAACCGACCGGAGAA		 6 45 -39 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0589 AUUCUUGGCUGGCCUCUUA
UAAGAACCGACCGGAGAAU		 54 0 54 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0590 UUCUUGGCUGGCCUCUUAC
AAGAACCGACCGGAGAAUG		 31 0 31 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0591 UCUUGGCUGGCCUCUUACU
AGAACCGACCGGAGAAUGA		 26 0 26 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0592 CUUGGCUGGCCUCUUACUU
GAACCGACCGGAGAAUGAA		 60 0 60 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0593 UUGGCUGGCCUCUUACUUG
AACCGACCGGAGAAUGAAC		 55 15 40 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0594 UGGCUGGCCUCUUACUUGG
ACCGACCGGAGAAUGAACC		 50 80 -30 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.487C>T,p.Arg163Trp rs59616921
22402445
aspsirna0595 UGCAGGAACUCAAUUCUCA
ACGUCCUUGAGUUAAGAGU		 49 70 -21 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0596 GCAGGAACUCAAUUCUCAG
CGUCCUUGAGUUAAGAGUC		 60 10 50 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0597 CAGGAACUCAAUUCUCAGC
GUCCUUGAGUUAAGAGUCG		 90 0 90 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0598 AGGAACUCAAUUCUCAGCU
UCCUUGAGUUAAGAGUCGA		 82 50 32 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0599 GGAACUCAAUUCUCAGCUG
CCUUGAGUUAAGAGUCGAC		 35 0 35 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0600 GAACUCAAUUCUCAGCUGG
CUUGAGUUAAGAGUCGACC		 49 0 49 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0601 AACUCAAUUCUCAGCUGGC
UUGAGUUAAGAGUCGACCG		 82 0 82 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0602 ACUCAAUUCUCAGCUGGCC
UGAGUUAAGAGUCGACCGG		 80 20 60 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0603 CUCAAUUCUCAGCUGGCCU
GAGUUAAGAGUCGACCGGA		 61 0 61 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0604 UCAAUUCUCAGCUGGCCUC
AGUUAAGAGUCGACCGGAG		 35 0 35 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0605 CAAUUCUCAGCUGGCCUCU
GUUAAGAGUCGACCGGAGA		 38 35 3 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0606 AAUUCUCAGCUGGCCUCUU
UUAAGAGUCGACCGGAGAA		 39 20 19 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0607 AUUCUCAGCUGGCCUCUUA
UAAGAGUCGACCGGAGAAU		 4 0 4 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0608 UUCUCAGCUGGCCUCUUAC
AAGAGUCGACCGGAGAAUG		 35 0 35 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0609 UCUCAGCUGGCCUCUUACU
AGAGUCGACCGGAGAAUGA		 76 20 56 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0610 CUCAGCUGGCCUCUUACUU
GAGUCGACCGGAGAAUGAA		 24 8 16 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0611 UCAGCUGGCCUCUUACUUG
AGUCGACCGGAGAAUGAAC		 48 42 6 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0612 CAGCUGGCCUCUUACUUGG
GUCGACCGGAGAAUGAACC		 56 39 17 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0613 AGCUGGCCUCUUACUUGGA
UCGACCGGAGAAUGAACCU		 81 23 58 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.488G>A,p.Arg163Gln rs57758262
22402445
aspsirna0614 GCUAAUGAGAAGAGCACCG
CGAUUACUCUUCUCGUGGC		 39 40 -1 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0615 CUAAUGAGAAGAGCACCGU
GAUUACUCUUCUCGUGGCA		 89 0 89 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0616 UAAUGAGAAGAGCACCGUG
AUUACUCUUCUCGUGGCAC		 0 18 -18 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0617 AAUGAGAAGAGCACCGUGC
UUACUCUUCUCGUGGCACG		 55 68 -13 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0618 AUGAGAAGAGCACCGUGCA
UACUCUUCUCGUGGCACGU		 80 24 56 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0619 UGAGAAGAGCACCGUGCAG
ACUCUUCUCGUGGCACGUC		 90 49 41 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0620 GAGAAGAGCACCGUGCAGG
CUCUUCUCGUGGCACGUCC		 100 50 50 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0621 AGAAGAGCACCGUGCAGGA
UCUUCUCGUGGCACGUCCU		 71 64 7 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0622 GAAGAGCACCGUGCAGGAA
CUUCUCGUGGCACGUCCUU		 80 25 55 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0623 AAGAGCACCGUGCAGGAAC
UUCUCGUGGCACGUCCUUG		 11 27 -16 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0624 AGAGCACCGUGCAGGAACU
UCUCGUGGCACGUCCUUGA		 40 35 5 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0625 GAGCACCGUGCAGGAACUC
CUCGUGGCACGUCCUUGAG		 0 50 -50 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0626 AGCACCGUGCAGGAACUCA
UCGUGGCACGUCCUUGAGU		 67 82 -15 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0627 GCACCGUGCAGGAACUCAA
CGUGGCACGUCCUUGAGUU		 70 70 0 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0628 CACCGUGCAGGAACUCAAU
GUGGCACGUCCUUGAGUUA		 90 42 48 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0629 ACCGUGCAGGAACUCAAUU
UGGCACGUCCUUGAGUUAA		 86 75 11 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0630 CCGUGCAGGAACUCAAUUC
GGCACGUCCUUGAGUUAAG		 42 82 -40 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0631 CGUGCAGGAACUCAAUUCU
GCACGUCCUUGAGUUAAGA		 92 70 22 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0632 GUGCAGGAACUCAAUUCUC
CACGUCCUUGAGUUAAGAG		 80 25 55 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.469A>G ,p.Met157Val rs58597584
22402445
aspsirna0633 CUAAUGAGAAGAGCACCAC
GAUUACUCUUCUCGUGGUG		 89 10 79 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0634 UAAUGAGAAGAGCACCACG
AUUACUCUUCUCGUGGUGC		 94 0 94 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0635 AAUGAGAAGAGCACCACGC
UUACUCUUCUCGUGGUGCG		 90 45 45 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0636 AUGAGAAGAGCACCACGCA
UACUCUUCUCGUGGUGCGU		 98 25 73 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0637 UGAGAAGAGCACCACGCAG
ACUCUUCUCGUGGUGCGUC		 90 30 60 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0638 GAGAAGAGCACCACGCAGG
CUCUUCUCGUGGUGCGUCC		 61 78 -17 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0639 AGAAGAGCACCACGCAGGA
UCUUCUCGUGGUGCGUCCU		 65 66 -1 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0640 GAAGAGCACCACGCAGGAA
CUUCUCGUGGUGCGUCCUU		 70 22 48 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0641 AAGAGCACCACGCAGGAAC
UUCUCGUGGUGCGUCCUUG		 73 36 37 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0642 AGAGCACCACGCAGGAACU
UCUCGUGGUGCGUCCUUGA		 34 30 4 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0643 GAGCACCACGCAGGAACUC
CUCGUGGUGCGUCCUUGAG		 48 48 0 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0644 AGCACCACGCAGGAACUCA
UCGUGGUGCGUCCUUGAGU		 50 75 -25 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0645 GCACCACGCAGGAACUCAA
CGUGGUGCGUCCUUGAGUU		 70 64 6 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0646 CACCACGCAGGAACUCAAU
GUGGUGCGUCCUUGAGUUA		 60 70 -10 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0647 ACCACGCAGGAACUCAAUU
UGGUGCGUCCUUGAGUUAA		 58 40 18 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0648 CCACGCAGGAACUCAAUUC
GGUGCGUCCUUGAGUUAAG		 30 78 -48 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0649 CACGCAGGAACUCAAUUCU
GUGCGUCCUUGAGUUAAGA		 49 48 1 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0650 ACGCAGGAACUCAAUUCUC
UGCGUCCUUGAGUUAAGAG		 35 70 -35 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445
aspsirna0651 CGCAGGAACUCAAUUCUCG
GCGUCCUUGAGUUAAGAGC		 90 70 20 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.470T>C,p.Met157Thr rs59510579
22402445