Total number of Results for Myh6 are 18
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna1896 AGGGCCUGUGUCACCCUCAGG
UCCCGGACACAGUGGGAGUCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1897 GGGCCUGUGUCACCCUCAGGU
CCCGGACACAGUGGGAGUCCA		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1898 GGCCUGUGUCACCCUCAGGUG
CCGGACACAGUGGGAGUCCAC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1899 GCCUGUGUCACCCUCAGGUGA
CGGACACAGUGGGAGUCCACU		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1900 CCUGUGUCACCCUCAGGUGAG
GGACACAGUGGGAGUCCACUC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1901 CUGUGUCACCCUCAGGUGAGG
GACACAGUGGGAGUCCACUCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1902 UGUGUCACCCUCAGGUGAGGG
ACACAGUGGGAGUCCACUCCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1903 GUGUCACCCUCAGGUGAGGGU
CACAGUGGGAGUCCACUCCCA		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1904 UGUCACCCUCAGGUGAGGGUG
ACAGUGGGAGUCCACUCCCAC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1905 GUCACCCUCAGGUGAGGGUGG
CAGUGGGAGUCCACUCCCACC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1906 UCACCCUCAGGUGAGGGUGGG
AGUGGGAGUCCACUCCCACCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1907 CACCCUCAGGUGAGGGUGGGG
GUGGGAGUCCACUCCCACCCC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1908 ACCCUCAGGUGAGGGUGGGGA
UGGGAGUCCACUCCCACCCCU		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1909 CCCUCAGGUGAGGGUGGGGAC
GGGAGUCCACUCCCACCCCUG		 78 70 8 Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1910 CCUCAGGUGAGGGUGGGGACC
GGAGUCCACUCCCACCCCUGG		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1911 CUCAGGUGAGGGUGGGGACCG
GAGUCCACUCCCACCCCUGGC		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1912 UCAGGUGAGGGUGGGGACCGA
AGUCCACUCCCACCCCUGGCU		 Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1913 CCCUCAGGUGAGGGUGGGGAC
GGGAGUCCACUCCCACCCCUG		 78 70 8 Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743