Total number of Results for Myh6 are 18
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna1896 AGGGCCUGUGUCACCCUCAGG
UCCCGGACACAGUGGGAGUCC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1897 GGGCCUGUGUCACCCUCAGGU
CCCGGACACAGUGGGAGUCCA
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1898 GGCCUGUGUCACCCUCAGGUG
CCGGACACAGUGGGAGUCCAC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1899 GCCUGUGUCACCCUCAGGUGA
CGGACACAGUGGGAGUCCACU
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1900 CCUGUGUCACCCUCAGGUGAG
GGACACAGUGGGAGUCCACUC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1901 CUGUGUCACCCUCAGGUGAGG
GACACAGUGGGAGUCCACUCC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1902 UGUGUCACCCUCAGGUGAGGG
ACACAGUGGGAGUCCACUCCC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1903 GUGUCACCCUCAGGUGAGGGU
CACAGUGGGAGUCCACUCCCA
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1904 UGUCACCCUCAGGUGAGGGUG
ACAGUGGGAGUCCACUCCCAC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1905 GUCACCCUCAGGUGAGGGUGG
CAGUGGGAGUCCACUCCCACC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1906 UCACCCUCAGGUGAGGGUGGG
AGUGGGAGUCCACUCCCACCC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1907 CACCCUCAGGUGAGGGUGGGG
GUGGGAGUCCACUCCCACCCC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1908 ACCCUCAGGUGAGGGUGGGGA
UGGGAGUCCACUCCCACCCCU
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1909 CCCUCAGGUGAGGGUGGGGAC
GGGAGUCCACUCCCACCCCUG
78 70 8 Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1910 CCUCAGGUGAGGGUGGGGACC
GGAGUCCACUCCCACCCCUGG
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1911 CUCAGGUGAGGGUGGGGACCG
GAGUCCACUCCCACCCCUGGC
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1912 UCAGGUGAGGGUGGGGACCGA
AGUCCACUCCCACCCCUGGCU
Moderate efficacy Moderate efficacy Poor discrimination Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743
aspsirna1913 CCCUCAGGUGAGGGUGGGGAC
GGGAGUCCACUCCCACCCCUG
78 70 8 Myh6 Human hypertrophic cardiomyopathy (HCM) c.2384G>A,p.Arg795Gln rs26760690
24092743