ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0001 | UUGUGAACCUGCUCAGCGA AACACUUGGACGAGUCGCU |
67 | 38 | 29 | RyR1 | Central core disease (CCD) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0002 | UUGUGAACCUGCUAAGCGA AACACUUGGACGAUUCGCU |
20 | 80 | -60 | RyR1 | Central core disease (CCD) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0003 | UUGUGAACCUGCUCUAUGA AACACUUGGACGAGAUACU |
82 | 35 | 47 | RyR1 | Central core disease (CCD) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0004 | CCUGCUCAGCGAACUUCUA GGACGAGUCGCUUGAAGAU |
46 | 20 | 26 | RyR1 | Central core disease (CCD) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0005 | GAGGGACCGGUGACGAGAU CUCCCUGGCCACUGCUCUA |
0 | 28 | -28 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0006 | GAGGGACCUGUGACGAGAU CUCCCUGGACACUGCUCUA |
36 | 0 | 36 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0007 | GAGGGAUCGGGGACGAGAU CUCCCUAGCCCCUGCUCUA |
39 | 0 | 39 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0008 | CCGGUGGAGGGACCGGUGA GGCCACCUCCCUGGCCACU |
0 | 25 | -25 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0009 | GAGGGACCAGUGACGAGAU CUCCCUGGUCACUGCUCUA |
38 | 20 | 18 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0010 | CCGGUGGAGGGAUCGGGGA GGCCACCUCCCUAGCCCCU |
40 | 20 | 20 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0011 | UUGUGAACCUGCUCAGCGA AACACUUGGACGAGUCGCU |
67 | 38 | 29 | RyR1 | Central core disease (CCD) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0012 | UUGUGAACCUGCUAAGCGA AACACUUGGACGAUUCGCU |
20 | 80 | -60 | RyR1 | Central core disease (CCD) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0013 | UUGUGAACCUGCUCUAUGA AACACUUGGACGAGAUACU |
82 | 35 | 47 | RyR1 | Central core disease (CCD) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0014 | CCUGCUCAGCGAACUUCUA GGACGAGUCGCUUGAAGAU |
46 | 20 | 26 | RyR1 | Central core disease (CCD) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0015 | GAGGGACCGGUGACGAGAU CUCCCUGGCCACUGCUCUA |
0 | 28 | -28 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0016 | GAGGGACCUGUGACGAGAU CUCCCUGGACACUGCUCUA |
36 | 0 | 36 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0017 | GAGGGAUCGGGGACGAGAU CUCCCUAGCCCCUGCUCUA |
39 | 0 | 39 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0018 | CCGGUGGAGGGACCGGUGA GGCCACCUCCCUGGCCACU |
0 | 25 | -25 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0019 | GAGGGACCAGUGACGAGAU CUCCCUGGUCACUGCUCUA |
38 | 20 | 18 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0020 | CCGGUGGAGGGAUCGGGGA GGCCACCUCCCUAGCCCCU |
40 | 20 | 20 | RyR1 | Central core disease (CCD) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0021 | UUGUGAACCUGCUCAGCGA AACACUUGGACGAGUCGCU |
67 | 38 | 29 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0022 | UUGUGAACCUGCUAAGCGA AACACUUGGACGAUUCGCU |
20 | 80 | -60 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0023 | UUGUGAACCUGCUCUAUGA AACACUUGGACGAGAUACU |
82 | 35 | 47 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0024 | CCUGCUCAGCGAACUUCUA GGACGAGUCGCUUGAAGAU |
46 | 20 | 26 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0025 | GAGGGACCGGUGACGAGAU CUCCCUGGCCACUGCUCUA |
0 | 28 | -28 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0026 | GAGGGACCUGUGACGAGAU CUCCCUGGACACUGCUCUA |
36 | 0 | 36 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0027 | GAGGGAUCGGGGACGAGAU CUCCCUAGCCCCUGCUCUA |
39 | 0 | 39 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0028 | CCGGUGGAGGGACCGGUGA GGCCACCUCCCUGGCCACU |
0 | 25 | -25 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0029 | GAGGGACCAGUGACGAGAU CUCCCUGGUCACUGCUCUA |
38 | 20 | 18 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0030 | CCGGUGGAGGGAUCGGGGA GGCCACCUCCCUAGCCCCU |
40 | 20 | 20 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0031 | UUGUGAACCUGCUCAGCGA AACACUUGGACGAGUCGCU |
67 | 38 | 29 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0032 | UUGUGAACCUGCUAAGCGA AACACUUGGACGAUUCGCU |
20 | 80 | -60 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0033 | UUGUGAACCUGCUCUAUGA AACACUUGGACGAGAUACU |
82 | 35 | 47 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0034 | CCUGCUCAGCGAACUUCUA GGACGAGUCGCUUGAAGAU |
46 | 20 | 26 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna0035 | GAGGGACCGGUGACGAGAU CUCCCUGGCCACUGCUCUA |
0 | 28 | -28 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0036 | GAGGGACCUGUGACGAGAU CUCCCUGGACACUGCUCUA |
36 | 0 | 36 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0037 | GAGGGAUCGGGGACGAGAU CUCCCUAGCCCCUGCUCUA |
39 | 0 | 39 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0038 | CCGGUGGAGGGACCGGUGA GGCCACCUCCCUGGCCACU |
0 | 25 | -25 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0039 | GAGGGACCAGUGACGAGAU CUCCCUGGUCACUGCUCUA |
38 | 20 | 18 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna0040 | CCGGUGGAGGGAUCGGGGA GGCCACCUCCCUAGCCCCU |
40 | 20 | 20 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna3124 | GAGGGACCGGUGACGAGAU CUCCCUGGCCACUGCUCUA |
10 | 28 | -18 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna3125 | GAGGGACCUGUGACGAGAU CUCCCUGGACACUGCUCUA |
45 | 10 | 35 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna3126 | GAGGGAUCGGGGACGAGAU CUCCCUAGCCCCUGCUCUA |
40 | 17 | 23 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna3127 | CCGGUGGAGGGACCGGUGA GGCCACCUCCCUGGCCACU |
10 | 25 | -15 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna3128 | GAGGGACCAGUGACGAGAU CUCCCUGGUCACUGCUCUA |
50 | 30 | 20 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna3129 | CCGGUGGAGGGAUCGGGGA GGCCACCUCCCUAGCCCCU |
40 | 30 | 10 | RyR1 | Malignanat Hyperthermia (MH) | c.14693T>C,p.Ile4898Thr | rs11819217 | ![]() |
|
aspsirna3130 | UUGUGAACCUGCUCAGCGA AACACUUGGACGAGUCGCU |
60 | 38 | 22 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna3131 | UUGUGAACCUGCUAAGCGA AACACUUGGACGAUUCGCU |
35 | 20 | 15 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna3132 | UUGUGAACCUGCUCUAUGA AACACUUGGACGAGAUACU |
80 | 35 | 45 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |
|
aspsirna3133 | CCUGCUCAGCGAACUUCUA GGACGAGUCGCUUGAAGAU |
45 | 20 | 25 | RyR1 | Malignanat Hyperthermia (MH) | c.1565A>C,p.Tyr522Ser | rs11819216 | ![]() |