Total number of Results for RyR1 are 50
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0001 UUGUGAACCUGCUCAGCGA
AACACUUGGACGAGUCGCU		 67 38 29 RyR1 Central core disease (CCD) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0002 UUGUGAACCUGCUAAGCGA
AACACUUGGACGAUUCGCU		 20 80 -60 RyR1 Central core disease (CCD) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0003 UUGUGAACCUGCUCUAUGA
AACACUUGGACGAGAUACU		 82 35 47 RyR1 Central core disease (CCD) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0004 CCUGCUCAGCGAACUUCUA
GGACGAGUCGCUUGAAGAU		 46 20 26 RyR1 Central core disease (CCD) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0005 GAGGGACCGGUGACGAGAU
CUCCCUGGCCACUGCUCUA		 0 28 -28 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0006 GAGGGACCUGUGACGAGAU
CUCCCUGGACACUGCUCUA		 36 0 36 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0007 GAGGGAUCGGGGACGAGAU
CUCCCUAGCCCCUGCUCUA		 39 0 39 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0008 CCGGUGGAGGGACCGGUGA
GGCCACCUCCCUGGCCACU		 0 25 -25 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0009 GAGGGACCAGUGACGAGAU
CUCCCUGGUCACUGCUCUA		 38 20 18 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0010 CCGGUGGAGGGAUCGGGGA
GGCCACCUCCCUAGCCCCU		 40 20 20 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0011 UUGUGAACCUGCUCAGCGA
AACACUUGGACGAGUCGCU		 67 38 29 RyR1 Central core disease (CCD) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0012 UUGUGAACCUGCUAAGCGA
AACACUUGGACGAUUCGCU		 20 80 -60 RyR1 Central core disease (CCD) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0013 UUGUGAACCUGCUCUAUGA
AACACUUGGACGAGAUACU		 82 35 47 RyR1 Central core disease (CCD) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0014 CCUGCUCAGCGAACUUCUA
GGACGAGUCGCUUGAAGAU		 46 20 26 RyR1 Central core disease (CCD) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0015 GAGGGACCGGUGACGAGAU
CUCCCUGGCCACUGCUCUA		 0 28 -28 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0016 GAGGGACCUGUGACGAGAU
CUCCCUGGACACUGCUCUA		 36 0 36 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0017 GAGGGAUCGGGGACGAGAU
CUCCCUAGCCCCUGCUCUA		 39 0 39 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0018 CCGGUGGAGGGACCGGUGA
GGCCACCUCCCUGGCCACU		 0 25 -25 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0019 GAGGGACCAGUGACGAGAU
CUCCCUGGUCACUGCUCUA		 38 20 18 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0020 CCGGUGGAGGGAUCGGGGA
GGCCACCUCCCUAGCCCCU		 40 20 20 RyR1 Central core disease (CCD) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0021 UUGUGAACCUGCUCAGCGA
AACACUUGGACGAGUCGCU		 67 38 29 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0022 UUGUGAACCUGCUAAGCGA
AACACUUGGACGAUUCGCU		 20 80 -60 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0023 UUGUGAACCUGCUCUAUGA
AACACUUGGACGAGAUACU		 82 35 47 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0024 CCUGCUCAGCGAACUUCUA
GGACGAGUCGCUUGAAGAU		 46 20 26 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0025 GAGGGACCGGUGACGAGAU
CUCCCUGGCCACUGCUCUA		 0 28 -28 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0026 GAGGGACCUGUGACGAGAU
CUCCCUGGACACUGCUCUA		 36 0 36 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0027 GAGGGAUCGGGGACGAGAU
CUCCCUAGCCCCUGCUCUA		 39 0 39 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0028 CCGGUGGAGGGACCGGUGA
GGCCACCUCCCUGGCCACU		 0 25 -25 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0029 GAGGGACCAGUGACGAGAU
CUCCCUGGUCACUGCUCUA		 38 20 18 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0030 CCGGUGGAGGGAUCGGGGA
GGCCACCUCCCUAGCCCCU		 40 20 20 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0031 UUGUGAACCUGCUCAGCGA
AACACUUGGACGAGUCGCU		 67 38 29 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0032 UUGUGAACCUGCUAAGCGA
AACACUUGGACGAUUCGCU		 20 80 -60 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0033 UUGUGAACCUGCUCUAUGA
AACACUUGGACGAGAUACU		 82 35 47 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0034 CCUGCUCAGCGAACUUCUA
GGACGAGUCGCUUGAAGAU		 46 20 26 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna0035 GAGGGACCGGUGACGAGAU
CUCCCUGGCCACUGCUCUA		 0 28 -28 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0036 GAGGGACCUGUGACGAGAU
CUCCCUGGACACUGCUCUA		 36 0 36 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0037 GAGGGAUCGGGGACGAGAU
CUCCCUAGCCCCUGCUCUA		 39 0 39 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0038 CCGGUGGAGGGACCGGUGA
GGCCACCUCCCUGGCCACU		 0 25 -25 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0039 GAGGGACCAGUGACGAGAU
CUCCCUGGUCACUGCUCUA		 38 20 18 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna0040 CCGGUGGAGGGAUCGGGGA
GGCCACCUCCCUAGCCCCU		 40 20 20 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna3124 GAGGGACCGGUGACGAGAU
CUCCCUGGCCACUGCUCUA		 10 28 -18 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna3125 GAGGGACCUGUGACGAGAU
CUCCCUGGACACUGCUCUA		 45 10 35 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna3126 GAGGGAUCGGGGACGAGAU
CUCCCUAGCCCCUGCUCUA		 40 17 23 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna3127 CCGGUGGAGGGACCGGUGA
GGCCACCUCCCUGGCCACU		 10 25 -15 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna3128 GAGGGACCAGUGACGAGAU
CUCCCUGGUCACUGCUCUA		 50 30 20 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna3129 CCGGUGGAGGGAUCGGGGA
GGCCACCUCCCUAGCCCCU		 40 30 10 RyR1 Malignanat Hyperthermia (MH) c.14693T>C,p.Ile4898Thr rs11819217
23152933
aspsirna3130 UUGUGAACCUGCUCAGCGA
AACACUUGGACGAGUCGCU		 60 38 22 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna3131 UUGUGAACCUGCUAAGCGA
AACACUUGGACGAUUCGCU		 35 20 15 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna3132 UUGUGAACCUGCUCUAUGA
AACACUUGGACGAGAUACU		 80 35 45 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933
aspsirna3133 CCUGCUCAGCGAACUUCUA
GGACGAGUCGCUUGAAGAU		 45 20 25 RyR1 Malignanat Hyperthermia (MH) c.1565A>C,p.Tyr522Ser rs11819216
23152933