| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2011 | UUUAUGAGUAUCUCUCUGA AAAUACUCAUAGAGAGACU |
60 | 30 | 30 | P. luciferase | NA | NA | NA | 
|
|
| aspsirna2106 | GGAGCUGUUGGCGUAGGCA CCUCGACAACCGCAUCCGU |
5 | 1 | 4 | KRAS | Cancer | c.35G>T,p.Gly12Val | rs12191352 |
|
|
| aspsirna2127 | GGAGCUGUUGGCGUAGGCA CCUCGACAACCGCAUCCGU |
5 | 1 | 4 | KRAS | Cancer | c.35G>T,p.Gly12Val | rs12191352 |
|
|
| aspsirna2237 | UUCAGCAGCAUCAGCAGCAGU AAGUCGUCGUAGUCGUCGUCU |
69 | 30 | 39 | ATN-1 | Dentatorubral-pallidoluysian atrophy (DRPLA) | c.1462_1464CAG(90_93) | rs19392293 |
|
|
| aspsirna0356 | UAUCAAAGUUCCAGCUGGG AUAGUUUCAAGGUCGACCC |
79 | 0 | 79 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 |
|
|
| aspsirna3038 | CAGCAGCAUCAGCAGCAGC GUCGUCGUAGUCGUCGUCG |
85 | 30 | 55 | ATXN3 | Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs19392292 |
|
|
| aspsirna0783 | CAGCAGCAUCAGCAGCAGC GUCGUCGUAGUCGUCGUCG |
48 | 52 | -4 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0071 | CAGUGAUCUUCAUCACCUU GUCACUAGAAGUAGUGGAA |
13 | 73 | -60 | APP | Alzheimers disease | c.2010_2011delGAinsTC (p.Lys670_Met671delinsAsnLeu) | rs28186516 |
|
|
| aspsirna3694 | GGUUGGAGGAGAGAUGAUA CCAACCUCAUCUCUACUAU |
90 | 53 | 37 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
|
| aspsirna3771 | AAAGUUGCGCGGAGGAGUU UUUCAACGAGCCUCCUCAA |
90 | 22 | 68 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
