| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2038 | CUCUCCUGUAGCUAAGGCU GAGAGGACAUCGAUUCCGA |
80 | 45 | 35 | PPIB/Cyclophilin B | NA | NA | NA | 
|
|
| aspsirna3152 | CGACGCUGCUUUGAGGCCU GCUGCGACGAAACUCCGGA |
42 | 61 | -19 | TP63 | Ectrodactily-ectodermal dysplasia and cleft lip/palate (EEC) | c.727C>T, p.Arg243Trp | rs12190883 |
|
|
| aspsirna3301 | UACUGUGUGCACUUCAUCCUG AUGACACACGUGAAGUAGGAC |
70 | 55 | 15 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 |
|
|
| aspsirna3322 | UGCCCUUGUGCCCUCCACCGA ACGGGAACACGGGAGGUGGCU |
11 | 0 | 11 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |
|
|
| aspsirna3047 | ACUCAGCUGUACACGGACU UGAGUCGACAUGUGCCUGA |
35 | 45 | -10 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 |
|
|
| aspsirna0576 | AUGCAGGAACUCAAUUCUU UACGUCCUUGAGUUAAGAA |
75 | 20 | 55 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.487C>T,p.Arg163Trp | rs59616921 |
|
|
| aspsirna1830 | AAGCAGCACAAUGAUGAGUGU UUCGUCGUGUUACUACUCACA |
NA | 72 | NA | Fen1 | Werner syndrome | NA | NA |
|
|
| aspsirna1763 | ACCGCUGGAGAGCAACUGU UGGCGACCUCUCGUUGACG |
NA | NA | NA | P. luciferase | NA | NA | NA |
|
