| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna1996 | UUUAUGAGGAUCUUUCUGA AAAUACUCCUAGAAAGACU |
90 | 30 | 60 | P. luciferase | NA | NA | NA | 
|
|
| aspsirna3147 | CUGCUUUGAGGCCUGGAUC GACGAAACUCCGGACCUAG |
75 | 10 | 65 | TP63 | Ectrodactily-ectodermal dysplasia and cleft lip/palate (EEC) | c.727C>T, p.Arg243Trp | rs12190883 |
|
|
| aspsirna3155 | CUGCUUUGAGGCCUGGAUC GACGAAACUCCGGACCUAG |
76 | 10 | 66 | TP63 | Ectrodactily-ectodermal dysplasia and cleft lip/palate (EEC) | c.727C>T, p.Arg243Trp | rs12190883 |
|
|
| aspsirna3296 | UCAUCUACUGUGUGCACUUCA AGUAGAUGACACACGUGAAGU |
70 | 62 | 8 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 |
|
|
| aspsirna3317 | GUCUGUGCCCUUGUGCCCUCC CAGACACGGGAACACGGGAGG |
60 | 42 | 18 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |
|
|
| aspsirna3052 | GCUGUACACGGACUGCACG CGACAUGUGCCUGACGUGC |
60 | 12 | 48 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 |
|
|
| aspsirna0581 | GGAACUCAAUUCUUGGCUG CCUUGAGUUAAGAACCGAC |
30 | 0 | 30 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.487C>T,p.Arg163Trp | rs59616921 |
|
|
| aspsirna0984 | CAGCAGCAGCAGCAGUAGCAG GUCGUCGUCGUCGUCAUCGUC |
60 | 23 | 37 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0988 | CAGCAGCAGCAGCAGUAGCAG GUCGUCGUCGUCGUCAUCGUC |
60 | 23 | 37 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0991 | CAGCAGCAGCAGCAGU GUCGUCGUCGUCGUCAUCGUC |
60 | 25 | 35 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0993 | CAGCAGCAGCAGCAGUA GUCGUCGUCGUCGUCAUCGUC |
60 | 25 | 35 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0995 | CAGCAGCAGCAGCAGU GUCGUCGUCGUCGUCAUCGUC |
60 | 25 | 35 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0997 | CAGCAGCAGCAGCAGUA GUCGUCGUCGUCGUCAUCGUC |
60 | 30 | 30 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0810 | GCCUUUGGAAGUCUGUGCCCA CGGAAACCUUCAGACACGGGU |
60 | 32 | 28 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 |
|
|
| aspsirna3598 | UCAGAGAGAUCCUCAUAAA AGUCUCUCUAGGAAUAUUU |
90 | 82 | 8 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
