| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2424 | AACUCCUCCGCGUAACUUU UUGAGGAGGCGCAUUGAAA |
32 | 70 | -38 | KRAS | NA | NA | NA | 
|
|
| aspsirna3146 | UGCUUUGAGGCCUGGAUCU ACGAAACUCCGGACCUAGA |
47 | 10 | 37 | TP63 | Ectrodactily-ectodermal dysplasia and cleft lip/palate (EEC) | c.727C>T, p.Arg243Trp | rs12190883 |
|
|
| aspsirna3295 | CUCAUCUACUGUGUGCACUUC GAGUAGAUGACACACGUGAAG |
50 | 41 | 9 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 |
|
|
| aspsirna3316 | AGUCUGUGCCCUUGUGCCCUC UCAGACACGGGAACACGGGAG |
40 | 15 | 25 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |
|
|
| aspsirna2233 | UUCAGCAGCAGCAGUAGCAGU AAGUCGUCGUCGUCAUCGUCU |
50 | 13 | 37 | ATN-1 | Dentatorubral-pallidoluysian atrophy (DRPLA) | c.1462_1464CAG(90_93) | rs19392293 |
|
|
| aspsirna3053 | CUGUACACGGACUGCACGG GACAUGUGCCUGACGUGCC |
20 | 35 | -15 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 |
|
|
| aspsirna0582 | GAACUCAAUUCUUGGCUGG CUUGAGUUAAGAACCGACC |
28 | 0 | 28 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.487C>T,p.Arg163Trp | rs59616921 |
|
|
| aspsirna3030 | CAGCAGCAGCAGUAGCAGC GUCGUCGUCGUCAUCGUCG |
80 | 70 | 10 | ATXN3 | Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs19392292 |
|
|
| aspsirna0778 | CAGCAGCAGCAGUAGCAGC GUCGUCGUCGUCAUCGUCG |
30 | 30 | 0 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0811 | CCUUUGGAAGUCUGUGCCCUA GGAAACCUUCAGACACGGGAU |
62 | 43 | 19 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 |
|
|
| aspsirna1780 | GCAGCUGCGCUAUGGCGAA CGUCGACGCGAUACCGCUU |
NA | 78 | NA | POLR2A | Cancer | c.2907C>T,(p.Ile969=) | rs14801110 |
|
|
| aspsirna1786 | GCAGCUGCGCUAUGGCGAA CGUCGACGCGAUACCGCUU |
NA | 78 | NA | POLR2A | Cancer | c.2907C>T,(p.Ile969=) | rs14801110 |
|
