| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2009 | UUUAUGAGGGUCUCUCUGA AAAUACUCCCAGAGAGACU |
3 | 30 | -27 | P. luciferase | NA | NA | NA | 
|
|
| aspsirna2066 | CUCUCCUGUGGCUAAGGCC GAGAGGACACCGAUUCCGG |
40 | 45 | -5 | PPIB/Cyclophilin B | NA | NA | NA |
|
|
| aspsirna2948 | CACUAGUAGGAAGUAUAAU GUGAUCAUCCUUCAUAUUA |
50 | 20 | 30 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2974 | CACUAGUAGGAAGUAUAAU GUGAUCAUCCUUCAUAUUA |
45 | 20 | 25 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3004 | CACUAGUAGGAAGUAUAAU GUGAUCAUCCUUCAUAUUA |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2177 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna3442 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 |
|
|
| aspsirna3452 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 |
|
|
| aspsirna3462 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 |
|
|
| aspsirna3472 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 |
|
|
| aspsirna3482 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 |
|
|
| aspsirna3492 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 30 | 40 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 |
|
|
| aspsirna0623 | AAGAGCACCGUGCAGGAAC UUCUCGUGGCACGUCCUUG |
11 | 27 | -16 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.469A>G ,p.Met157Val | rs58597584 |
|
|
| aspsirna0842 | AAGCUGCUGCUGCAGAUCAAC UUCGACGACGACGUCUAGUUG |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 |
|
|
| aspsirna0053 | GUUUGAGCUGAUGUAUGUG CAAACUCGACUACAUACAC |
90 | 20 | 70 | HTT | Huntington disease (HD) | c.8163G>A,c.52CAG(36_39) | rs2276881 |
|
|
| aspsirna3691 | GGUUGGAGGAGAGAUGAUA CCAACCUCCCCUCUACUAU |
90 | 75 | 15 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
