ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
aspsirna0468 | UCCUGGAGCAGCAGAAGAA AGGACCUCGUCGUCUUCUU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ![]() |
|
aspsirna0506 | UCCUGGAGCAGCAGAAGAA AGGACCUCGUCGUCUUCUU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ![]() |
|
aspsirna0444 | CAUUUUCUACAGUGUUGUG GUAAAAGAUGUCACAACAC |
82 | 0 | 82 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ![]() |
|
aspsirna0113 | CGAGUAAGCUAAAAACGAA GCUCAUUCGAUUUUUGCUU |
0 | 99 | -99 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0152 | CGAGUAAGCUAAAAACGAA GCUCAUUCGAUUUUUGCUU |
0 | 99 | -99 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |