| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna1991 | UUUAUGAGGAUCUCUGUGA AAAUACUCCUAGAGACACU |
45 | 30 | 15 | P. luciferase | NA | NA | NA | 
|
|
| aspsirna2416 | AACUCCUCCGCGCAAGUUU UUGAGGAGGCGCGUUCAAA |
46 | 70 | -24 | KRAS | NA | NA | NA |
|
|
| aspsirna0469 | CCUGGAGCAGCAGAAGAAG GGACCUCGUCGUCUUCUUC |
34 | 0 | 34 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 |
|
|
| aspsirna0507 | CCUGGAGCAGCAGAAGAAG GGACCUCGUCGUCUUCUUC |
34 | 0 | 34 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 |
|
|
| aspsirna0540 | UUCAAUAUAAAGGCUGGCG AAGUUAUAUUUCCGACCGC |
37 | 8 | 29 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 |
|
|
| aspsirna0443 | AUUUUCUACAGUGUUGUGG UAAAAGAUGUCACAACACC |
6 | 0 | 6 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 |
|
|
| aspsirna0112 | CGAGUAAGCUAAAAAGCAA GCUCAUUCGAUUUUUCGUU |
39 | 99 | -60 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 |
|
|
| aspsirna0151 | CGAGUAAGCUAAAAAGCAA GCUCAUUCGAUUUUUCGUU |
39 | 99 | -60 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 |
|
