ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
aspsirna1997 | UUUAUGAGGAUCUGUCUGA AAAUACUCCUAGACAGACU |
40 | 30 | 10 | P. luciferase | NA | NA | NA | ![]() |
|
aspsirna0471 | UGGAGCAGCAGAAGAAGGU ACCUCGUCGUCUUCUUCCA |
50 | 0 | 50 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ![]() |
|
aspsirna0509 | UGGAGCAGCAGAAGAAGGU ACCUCGUCGUCUUCUUCCA |
50 | 0 | 50 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ![]() |
|
aspsirna0441 | UUUCUACAGUGUUGUGGUU AAAGAUGUCACAACACCAA |
15 | 0 | 15 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ![]() |
|
aspsirna3599 | UCAGAGAGAUCCUCAUAAA AGUCUCUCUAGGACUAUUU |
90 | 72 | 18 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA | ![]() |
|
aspsirna1812 | GCGCUUCAGGCACUAGAAAUA CGCGAAGUCCGUGAUCUUUAU |
NA | NA | NA | F3 /CD142 | Malignant melanoma | c.489G>A,p.Arg163= | rs26759878 | ![]() |