ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
aspsirna2425 | AACUCCUCCGCGGAACUUU UUGAGGAGGCGCCUUGAAA |
28 | 70 | -42 | KRAS | NA | NA | NA | ![]() |
|
aspsirna0472 | GGAGCAGCAGAAGAAGGUU CCUCGUCGUCUUCUUCCAA |
70 | 0 | 70 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ![]() |
|
aspsirna0510 | GGAGCAGCAGAAGAAGGUU CCUCGUCGUCUUCUUCCAA |
70 | 0 | 70 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 | ![]() |
|
aspsirna0440 | UUCUACAGUGUUGUGGUUG AAGAUGUCACAACACCAAC |
37 | 0 | 37 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ![]() |
|
aspsirna0943 | AUGUCCUUCAAGGAGCAGC UACAGGAAGUUCCUCGUCG |
42 | 50 | -8 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ![]() |