| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2431 | AACUCCUCCGGGCAACUUU UUGAGGAGGCCCGUUGAAA |
33 | 70 | -37 | KRAS | NA | NA | NA | 
|
|
| aspsirna0656 | GAUAGGUCCCGCUGCUGCU CUAUCCAGGGCGACGACGA |
25 | 50 | -25 | ATXN3 | Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) | c.892_894CAG(8_36),(p.Gln298_Gln305=) | rs19392292 |
|
|
| aspsirna0474 | AGCAGCAGAAGAAGGUUCU UCGUCGUCUUCUUCCAAGA |
10 | 0 | 10 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 |
|
|
| aspsirna0512 | AGCAGCAGAAGAAGGUUCU UCGUCGUCUUCUUCCAAGA |
10 | 0 | 10 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 |
|
|
| aspsirna0438 | CUACAGUGUUGUGGUUGGU GAUGUCACAACACCAACCA |
0 | 0 | 0 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 |
|
|
| aspsirna3611 | UCAGAGAGAUCCUCAUAAA AGUCUCUCUACGAGUAUUU |
90 | 55 | 35 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
|
| aspsirna1811 | GCGCUUCAGGCAGUACAAAUA CGCGAAGUCCGUCAUGUUUAU |
NA | NA | NA | F3 /CD142 | Malignant melanoma | c.489G>A,p.Arg163= | rs26759878 |
|
