| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2010 | UUUAUGAGGCUCUCUCUGA AAAUACUCCGAGAGAGACU |
45 | 30 | 15 | P. luciferase | NA | NA | NA | 
|
|
| aspsirna2067 | CUCUCCUGUCGCUAAGGCC GAGAGGACAGCGAUUCCGG |
30 | 45 | -15 | PPIB/Cyclophilin B | NA | NA | NA |
|
|
| aspsirna2949 | CACUAGUAGCAAGUAUAAU GUGAUCAUCGUUCAUAUUA |
50 | 20 | 30 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2975 | CACUAGUAGCAAGUAUAAU GUGAUCAUCGUUCAUAUUA |
24 | 20 | 4 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3005 | CACUAGUAGCAAGUAUAAU GUGAUCAUCGUUCAUAUUA |
70 | 20 | 50 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2173 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
80 | 5 | 75 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna2178 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna3438 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
80 | 5 | 75 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3443 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |
|
|
| aspsirna3448 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
80 | 5 | 75 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3453 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |
|
|
| aspsirna3458 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 67 | 30 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3463 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |
|
|
| aspsirna3468 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 67 | 30 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3473 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |
|
|
| aspsirna3478 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 30 | 67 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3483 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |
|
|
| aspsirna3488 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 67 | 30 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3493 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |
|
|
| aspsirna0696 | CAGUGGCUCCCCUGAUUAC GUCACCGAGGGGACUAAUG |
76 | 20 | 56 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0456 | AAGUUUGCCCCCUUCAUCG UUCAAACGGGGGAAGUAGC |
30 | 0 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna0494 | AAGUUUGCCCCCUUCAUCG UUCAAACGGGGGAAGUAGC |
30 | 0 | 30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna0837 | UGGGGACAGUACUUCAACGCU ACCCCUGUCAUGAAGUUGCGA |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs363125 |
|
|
| aspsirna0839 | CAGUACUUCAACGCUAGAAGA GUCAUGAAGUUGCGAUCUUCU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs363125 |
|
|
| aspsirna3692 | GGUUGGAGGAGAGAUGAUA CCAACCUCCGCUCUACUAU |
90 | 40 | 50 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
