Total number of Results for G13C are 11
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0216 GAAGCACCAGGAAAGACAA
CUUCGUGGUCCUUUCUGUU		 40 0 40 SNCA Parkinsons disease (PD) c.88G>C,p.Ala30Pro rs10489387
22031823
aspsirna0230 GAAGCACCAGGAAAGACAA
CUUCGUGGUCCUUUCUGUU		 40 10 30 SNCA Parkinsons disease (PD) c.88G>C,p.Ala30Pro rs10489387
22031823
aspsirna0717 GACUUGCGCAAUGUGACUG
CUGAACGCGUUACACUGAC		 62 28 34 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C, p.Gly86Arg rs12191243
16965178
aspsirna0737 GACUUGCGCAAUGUGACUG
CUGAACGCGUUACACUGAC		 62 28 34 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C, p.Gly86Arg rs12191243
16965178
aspsirna0960 AUGAUACAUUAGCUUCCUA
UACUAUGUAAUCGAAGGAU		 92 0 92 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna2260 GACUUGCGCAAUGUGACUG
CUGAACGCGUUACACUGAC		 90 15 75 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
US2007/0259827A1
aspsirna2272 GACUUGCGCAAUGUGACUG
CUGAACGCGUUACACUGAC		 90 25 65 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
US2007/0259827A1
aspsirna2289 GACUUGCGCAAUGUGACUG
CUGAACGCGUUACACUGAC		 60 20 40 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
US2007/0259827A1
aspsirna2327 GACUUGCGCAAUGUGACUG
CUGAACGCGUUACACUGAC		 NA NA 65 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
US2007/0259827A1
aspsirna3521 AUGAUACAUUAGCUUCCUA
UACUAUGUAAUCGAAGGAU		 92 0 92 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3780 AAAGUUGCGCGGAGGAGUU
UUUCAAGGCGCCUCCUCAA		 90 25 65 PPIB/Cyclophilin B PPIB-Related Osteogenesis Imperfecta (Type IX) NA NA
16489337