| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna0173 | GAAACUAUGCAAAAUCCUA CUUUGAUACGUUUUAGGAU |
88 | 65 | 23 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | 
|
|
| aspsirna0449 | CAACAAUAAGUUUGCCCCC GUUGUUAUUCAAACGGGGG |
0 | 60 | -60 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna0487 | CAACAAUAAGUUUGCCCCC GUUGUUAUUCAAACGGGGG |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna0635 | AAUGAGAAGAGCACCACGC UUACUCUUCUCGUGGUGCG |
90 | 45 | 45 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.470T>C,p.Met157Thr | rs59510579 |
|
|
| aspsirna0746 | GCAUGUUGGAGACUUGCGC CGUACAACCUCUGAACGCG |
92 | 38 | 54 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna1817 | AAGCAGCACAAUGAUGAGCGC UUCGUCGUGUUACUACUCGCG |
NA | 75 | NA | Fen1 | Werner syndrome | NA | NA |
|
|
| aspsirna1988 | UUUAUGAGGAUCUCUCCGA AAAUACUCCUAGAGAGGCU |
88 | 30 | 58 | P. luciferase | NA | NA | NA |
|
|
| aspsirna2298 | GCAUGUUGGAGACUUGCGC CGUACAACCUCUGAACGCG |
82 | 30 | 52 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna2413 | AACUCCUCCGCGCAACCUU UUGAGGAGGCGCGUUGGAA |
82 | 70 | 12 | KRAS | NA | NA | NA |
|
|
| aspsirna3278 | UCCACUGUGUGCACUUCAUCC AGGUGACACACGUGAAGUAGG |
42 | 40 | 2 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 |
|