| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2302 | GUUGGAGACUUGCGCAAUG CAACCUCUGAACGCGUUAC |
85 | 90 | -5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | 
|
|
| aspsirna2000 | UUUAUGAGGAUCCCUCUGA AAAUACUCCUAGGGAGACU |
60 | 30 | 30 | P. luciferase | NA | NA | NA |
|
|
| aspsirna2057 | CUCUCCUGUAGCCAAGGCC GAGAGGACAUCGGUUCCGG |
62 | 45 | 17 | PPIB/Cyclophilin B | NA | NA | NA |
|
|
| aspsirna3274 | CUCAUCCACUGUGUGCACUUC GAGUAGGUGACACACGUGAAG |
60 | 50 | 10 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 |
|
|
| aspsirna0639 | AGAAGAGCACCACGCAGGA UCUUCUCGUGGUGCGUCCU |
65 | 66 | -1 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.470T>C,p.Met157Thr | rs59510579 |
|
|
| aspsirna0177 | CUAUGCAAAAUCCUAAUGA GAUACGUUUUAGGAUUACU |
82 | 10 | 72 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 |
|
|
| aspsirna0453 | AAUAAGUUUGCCCCCUUCA UUAUUCAAACGGGGGAAGU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna0491 | AAUAAGUUUGCCCCCUUCA UUAUUCAAACGGGGGAAGU |
40 | 0 | 40 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna1779 | CAGCUGCGCUACGGCGAA GUCGACGCGAUGCCGCUU |
NA | 50 | NA | POLR2A | Cancer | c.2907C>T,(p.Ile969=) | rs14801110 |
|
|
| aspsirna1785 | CAGCUGCGCUACGGCGAA GUCGACGCGAUGCCGCUU |
NA | 50 | NA | POLR2A | Cancer | c.2907C>T,(p.Ile969=) | rs14801110 |
|
|
| aspsirna0553 | UGCUCAGUAUGACGGAAAA ACGAGUCAUACUGCCUUUU |
45 | NA | NA | COL1A2 | Osteogenesis Imperfecta (OI) | c.246T>C,NP_000080.2:p.Asp82= | rs1800222 |
|
|
| aspsirna0750 | GUUGGAGACUUGCGCAAUG CAACCUCUGAACGCGUUAC |
94 | 92 | 2 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna3603 | UCAGAGAGAUCCUCAUAAA AGUCUCUCUAGGGGUAUUU |
90 | 85 | 5 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
|
| aspsirna1818 | AAGCAGCACAAUGACGAGUGC UUCGUCGUGUUACUGCUCACG |
NA | 38 | NA | Fen1 | Werner syndrome | NA | NA |
|
