| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna3187 | CACAGUUUCGACAUGUCCU GUGUCAAAGCUGUACAGGA |
83 | 0 | 83 | TP63 | Ectrodactyly-Ectodermal Dysplasia-Clefting syndrome 3 (EEC3) | p.Arg132His,c.394G>A | rs19392114 | 
|
|
| aspsirna3101 | AGGUUGUGAGGCACUGCCC UCCAACACUCCGUGACGGG |
80 | 30 | 50 | TP53 | Cancer | c.524G>A ,p.Arg175His | rs28934578 |
|
|
| aspsirna3108 | AGGUUGUGAGGCACUGCCC UCCAACACUCCGUGACGGG |
80 | 30 | 50 | TP53 | Cancer | c.524G>A ,p.Arg175His | rs28934578 |
|
|
| aspsirna1900 | CCUGUGUCACCCUCAGGUGAG GGACACAGUGGGAGUCCACUC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 |
|
|
| aspsirna0601 | AACUCAAUUCUCAGCUGGC UUGAGUUAAGAGUCGACCG |
82 | 0 | 82 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.488G>A,p.Arg163Gln | rs57758262 |
|
|
| aspsirna0328 | AUUCCCAGGCUCCCAGGCA UAAGGGUCCGAGGGUCCGU |
30 | 10 | 20 | COL7A1 | Dominant dystrophic epidermolysis bullosa(DDEB) | c.6127G>A,p.Gly2043Arg | rs12191283 |
|
|
| aspsirna0247 | AUUGCUGACUACAGCAUUG UAACGACUGAUGUCGUAAC |
40 | 27 | 13 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0882 | CAAGACCCUCAAAAACAAG GUUCUGGGAGUUUUUGUUC |
30 | 2 | 28 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna3680 | GGUUGGAGGAGAGAUGAUA CCAACCUCCUCUUUACUAU |
90 | 85 | 5 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
