Total number of Results for 12782788 are 12
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0201 CAGCAGCAGCGGGACCUAUC
GUCGUCGUCGCCCUGGAUAG		 66 62 4 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.G987C,c.892_894CAG(8_36) (p.Gln298_Gln305=) rs19392292
12782788
aspsirna0202 CAGCAGCCGGACCUAUCAGGAC
GUCGUCGGCCUGGAUAGUCCUG		 80 20 60 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.G987C,c.892_894CAG(8_36) (p.Gln298_Gln305=) rs19392292
12782788
aspsirna0203 CAGCAGCGGGACCUAUCAGGAC
GUCGUCGCCCUGGAUAGUCCUG		 55 0 55 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.G987C,c.892_894CAG(8_36) (p.Gln298_Gln305=) rs19392292
12782788
aspsirna0204 CAGCAGCAGGGGGACCUAUC
GUCGUCGUCCCCCUGGAUAG		 40 22 18 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.G987C,c.892_894CAG(8_36) (p.Gln298_Gln305=) rs19392292
12782788
aspsirna0205 UUGAAAAACAGCAGCAAAAGC
AACUUUUUGUCGUCGUUUUCG		 65 20 45 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.G987C,c.892_894CAG(8_36) (p.Gln298_Gln305=) rs19392292
12782788
aspsirna0206 CAGCAGCAGCAGCAGCAGCAGC
GUCGUCGUCGUCGUCGUCGUCG		 46 NA NA ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.G987C,c.892_894CAG(8_36) (p.Gln298_Gln305=) rs19392292
12782788
aspsirna0207 CAGCCGGGAGUCGGGAAGGUGC
GUCGGCCCUCAGCCCUUCCACG		 43 NA NA MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0208 ACGUCCUCGGCGGCGGCAGUGUGC
UGCAGGAGCCGCCGCCGUCACACG		 80 NA NA MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0209 ACGUCUCCAUGGCAUCUCAGC
UGCAGAGGUACCGUAGAGUCG		 17 85 -68 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0210 GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG		 65 60 5 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0211 GUGGCCACAUGGAAGUAAAAUC
CACCGGUGUACCUUCAUUUUAG		 65 0 65 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0212 GUGGCCAGAUGCAAGUAAAAUC
CACCGGUCUACGUUCAUUUUAG		 28 55 -27 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788