ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0343 | AAGAGGAGGAG---GCCGACGCCC UUCUCCUCCUC---CGGCUGCGGG |
83 | 10 | 73 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0344 | GAAGAGGAGGAG---GCCGACGCC CUUCUCCUCCUC---CGGCUGCGG |
79 | 0 | 79 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0345 | GACGAGGAAGAGGAGGAG---GCC CUGCUCCUUCUCCUCCUC---CGG |
68 | 0 | 68 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0346 | GAGGAAGAGGAGGAG---GCCGAC CUCCUUCUCCUCCUC---CGGCUG |
74 | 72 | 2 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |