ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0806 | CGGAGCCUUUGGAAGUCUGUA GCCUCGGAAACCUUCAGACAU |
78 | 22 | 56 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0807 | GGAGCCUUUGGAAGUCUGUGA CCUCGGAAACCUUCAGACACU |
65 | 47 | 18 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0808 | GAGCCUUUGGAAGUCUGUGCA CUCGGAAACCUUCAGACACGU |
68 | 34 | 34 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0809 | AGCCUUUGGAAGUCUGUGCCA UCGGAAACCUUCAGACACGGU |
88 | 61 | 27 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0810 | GCCUUUGGAAGUCUGUGCCCA CGGAAACCUUCAGACACGGGU |
60 | 32 | 28 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0811 | CCUUUGGAAGUCUGUGCCCUA GGAAACCUUCAGACACGGGAU |
62 | 43 | 19 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0812 | CUUUGGAAGUCUGUGCCCUUA GAAACCUUCAGACACGGGAAU |
92 | 77 | 15 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0813 | UUUGGAAGUCUGUGCCCUUGA AAACCUUCAGACACGGGAACU |
55 | 38 | 17 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0814 | UUGGAAGUCUGCGCCCUUGUG AACCUUCAGACGCGGGAACAC |
70 | 20 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0815 | UUGGAAGUCUGUGCCCUUGUA AACCUUCAGACACGGGAACAU |
65 | 15 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0816 | UUGGAAGUCUGUGCCCUUGCG AACCUUCAGACACGGGAACGC |
69 | 15 | 54 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0817 | UUGGAAGUCUGUGCCCUUAUG AACCUUCAGACACGGGAAUAC |
70 | 20 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0818 | UUGGAAGUCUGUGCCCUGGUG AACCUUCAGACACGGGACCAC |
34 | 23 | 11 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0819 | UUGGAAGUCUGUGCCCGUGUG AACCUUCAGACACGGGCACAC |
54 | 25 | 29 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0820 | UUGGAAGUCUGUGCCAUUGUG AACCUUCAGACACGGUAACAC |
57 | 30 | 27 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0821 | UUGGAAGUCUGUGCACUUGUG AACCUUCAGACACGUGAACAC |
80 | 50 | 30 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0822 | UUGGAAGUCUGUGCCAUUGUG AACCUUCAGACACGGUAACAC |
70 | 45 | 25 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0823 | GAAGUCUGUGCCCUUGUGCCA CUUCAGACACGGGAACACGGU |
65 | 20 | 45 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0824 | GUCUGUGCCCUUGUGCCCUGC CAGACACGGGAACACGGGACG |
58 | 37 | 21 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0825 | GUCUGUGCCCUUGUGCCCUAC CAGACACGGGAACACGGGAUG |
58 | 37 | 21 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0826 | GUCUGUGCCCUUGUGCCCGGC CAGACACGGGAACACGGGCCG |
43 | 12 | 31 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0827 | GUCUGUGCCCUUGUGCCAUGC CAGACACGGGAACACGGUACG |
55 | 36 | 19 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0828 | GUCUGUGCCCUUGUGCACUGC CAGACACGGGAACACGUGACG |
55 | 43 | 12 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0829 | GUCUGUGCCCUUGUGACCUGC CAGACACGGGAACACUGGACG |
46 | 30 | 16 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0830 | GUCUGUGCCCUUGUACCCUGC CAGACACGGGAACAUGGGACG |
80 | 50 | 30 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0831 | GUCUGUUCCCUUGUGCCCUGC CAGACAAGGGAACACGGGACG |
54 | 41 | 13 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0832 | GUCUGUACCCUUGUGCCCUGC CAGACAUGGGAACACGGGACG |
87 | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0833 | GUCUAUGCCCUUGUGCCCUGC CAGAUACGGGAACACGGGACG |
76 | 16 | 60 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0834 | GUCUUUGCCCUUGUGCCCUGC CAGAAACGGGAACACGGGACG |
86 | 42 | 44 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0835 | GUCAUUGCCCUUGUGCCCUGC CAGUAACGGGAACACGGGACG |
86 | 42 | 44 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0836 | AGUCUAUGCCCUUGUGCCCUG UCAGAUACGGGAACACGGGAC |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362307 | ||
aspsirna0837 | UGGGGACAGUACUUCAACGCU ACCCCUGUCAUGAAGUUGCGA |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs363125 | ||
aspsirna0838 | UGGGGACAGUAAUUCAACGCU ACCCCUGUCAUUAAGUUGCGA |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs363125 | ||
aspsirna0839 | CAGUACUUCAACGCUAGAAGA GUCAUGAAGUUGCGAUCUUCU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs363125 | ||
aspsirna0840 | CAGUAAUUCAACGCUAGAAGA GUCAUUAAGUUGCGAUCUUCU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs363125 | ||
aspsirna0841 | AAGCUGCUGCUACAGAUCAAC UUCGACGACGAUGUCUAGUUG |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0842 | AAGCUGCUGCUGCAGAUCAAC UUCGACGACGACGUCUAGUUG |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0843 | CUGCUACAGAUCAACCCCGAG GACGAUGUCUAGUUGGGGCUC |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0844 | CUGCUGCAGAUCAACCCCGAG GACGACGUCUAGUUGGGGCUC |
23 | 9 | 14 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0845 | AAGCUGCUGCUACAGAUCAGA UUCGACGACGAUGUCUAGUCU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0846 | AAGCUGCUGCUACAGAUCGAA UUCGACGACGAUGUCUAGCUU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0847 | AAGCUGCUGCUACAGAUAAAA UUCGACGACGAUGUCUAUUUU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0848 | AAGCUGCUGCUACAGAGCAAA UUCGACGACGAUGUCUCGUUU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0849 | AAGCUGCUGCUACAGGUCAAA UUCGACGACGAUGUCCAGUUU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0850 | AAGCUGCUGCUACAAAUCAAA UUCGACGACGAUGUUUAGUUU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 | ||
aspsirna0851 | AAGCUGCUGCUGCAGAGCAAA UUCGACGACGACGUCUCGUUU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs362273 |