ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3121 | GAUCAAGACCCUCAAAAAC CUAGUUCUGGGAGUUUUUG |
56 | 42 | 14 | KRT6A | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ![]() |
|
aspsirna3122 | CCCUCAAAAACAAGUUUGC GGGAGUUUUUGUUCAAACG |
35 | 0 | 35 | KRT6A | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ![]() |
|
aspsirna3123 | CCCUCAAAAACAAGUUUGC GGGAGUUUUUGUUCAAACG |
55 | 10 | 45 | KRT6A | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ![]() |