ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0348 | UUCCAGCUGGGAUACCUGG AAGGUCGACCCUAUGGACC |
74 | 76 | -2 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0349 | GUUCCAGCUGGGAUACCUG CAAGGUCGACCCUAUGGAC |
50 | 58 | -8 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0350 | AGUUCCAGCUGGGAUACCU UCAAGGUCGACCCUAUGGA |
24 | 0 | 24 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0351 | AAGUUCCAGCUGGGAUACC UUCAAGGUCGACCCUAUGG |
45 | 0 | 45 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0352 | AAAGUUCCAGCUGGGAUAC UUUCAAGGUCGACCCUAUG |
54 | 67 | -13 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0353 | CAAAGUUCCAGCUGGGAUA GUUUCAAGGUCGACCCUAU |
39 | 0 | 39 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0354 | UCAAAGUUCCAGCUGGGAU AGUUUCAAGGUCGACCCUA |
10 | 5 | 5 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0355 | AUCAAAGUUCCAGCUGGGA UAGUUUCAAGGUCGACCCU |
82 | 0 | 82 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0356 | UAUCAAAGUUCCAGCUGGG AUAGUUUCAAGGUCGACCC |
79 | 0 | 79 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0357 | GUAUCAAAGUUCCAGCUGG CAUAGUUUCAAGGUCGACC |
90 | 10 | 80 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0358 | GGUAUCAAAGUUCCAGCUG CCAUAGUUUCAAGGUCGAC |
75 | 2 | 73 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0359 | AGGUAUCAAAGUUCCAGCU UCCAUAGUUUCAAGGUCGA |
80 | 5 | 75 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0360 | CAGGUAUCAAAGUUCCAGC GUCCAUAGUUUCAAGGUCG |
15 | 12 | 3 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0361 | CCAGGUAUCAAAGUUCCAG GGUCCAUAGUUUCAAGGUC |
3 | 3 | 0 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0362 | UCCAGGUAUCAAAGUUCCA AGGUCCAUAGUUUCAAGGU |
22 | 0 | 22 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0363 | CUCCAGGUAUCAAAGUUCC GAGGUCCAUAGUUUCAAGG |
20 | 4 | 16 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0364 | CCUCCAGGUAUCAAAGUUC GGAGGUCCAUAGUUUCAAG |
60 | 13 | 47 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0365 | ACCUCCAGGUAUCAAAGUU UGGAGGUCCAUAGUUUCAA |
55 | 14 | 41 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ||
aspsirna0366 | GACCUCCAGGUAUCAAAGU CUGGAGGUCCAUAGUUUCA |
86 | 62 | 24 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 |