Total number of Results for 23233254 are 38
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0948 UGCAAAAUCUUAAUGAUAC
ACGUUUUAGAAUUACUAUG
45 30 15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0949 GCAAAAUCUUAAUGAUACA
CGUUUUAGAAUUACUAUGU
35 45 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0950 CAAAAUCUUAAUGAUACAU
GUUUUAGAAUUACUAUGUA
82 20 62 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0951 AAAAUCUUAAUGAUACAUU
UUUUAGAAUUACUAUGUAA
10 20 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0952 AAAUCUUAAUGAUACAUUA
UUUAGAAUUACUAUGUAAU
40 40 0 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0953 AAUCUUAAUGAUACAUUAG
UUAGAAUUACUAUGUAAUC
79 50 29 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0954 AUCUUAAUGAUACAUUAGC
UAGAAUUACUAUGUAAUCG
83 50 33 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0955 UCUUAAUGAUACAUUAGCU
AGAAUUACUAUGUAAUCGA
90 45 45 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0956 CUUAAUGAUACAUUAGCUU
GAAUUACUAUGUAAUCGAA
41 40 1 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0957 UUAAUGAUACAUUAGCUUC
AAUUACUAUGUAAUCGAAG
60 20 40 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0958 UAAUGAUACAUUAGCUUCC
AUUACUAUGUAAUCGAAGG
90 0 90 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0959 AAUGAUACAUUAGCUUCCU
UUACUAUGUAAUCGAAGGA
88 10 78 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0960 AUGAUACAUUAGCUUCCUA
UACUAUGUAAUCGAAGGAU
92 0 92 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0961 UGAUACAUUAGCUUCCUAC
ACUAUGUAAUCGAAGGAUG
90 56 34 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0962 GAUACAUUAGCUUCCUACC
CUAUGUAAUCGAAGGAUGG
30 20 10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0963 AUACAUUAGCUUCCUACCU
UAUGUAAUCGAAGGAUGGA
10 25 -15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0964 UACAUUAGCUUCCUACCUG
AUGUAAUCGAAGGAUGGAC
20 30 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0965 ACAUUAGCUUCCUACCUGG
UGUAAUCGAAGGAUGGACC
60 30 30 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0966 CAUUAGCUUCCUACCUGGA
GUAAUCGAAGGAUGGACCU
36 60 -24 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3509 UGCAAAAUCUUAAUGAUAC
ACGUUUUAGAAUUACUAUG
45 30 15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3510 GCAAAAUCUUAAUGAUACA
CGUUUUAGAAUUACUAUGU
35 20 15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3511 CAAAAUCUUAAUGAUACAU
GUUUUAGAAUUACUAUGUA
82 33 49 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3512 AAAAUCUUAAUGAUACAUU
UUUUAGAAUUACUAUGUAA
10 20 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3513 AAAUCUUAAUGAUACAUUA
UUUAGAAUUACUAUGUAAU
40 40 0 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3514 AAUCUUAAUGAUACAUUAG
UUAGAAUUACUAUGUAAUC
79 50 29 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3515 AUCUUAAUGAUACAUUAGC
UAGAAUUACUAUGUAAUCG
83 50 33 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3516 UCUUAAUGAUACAUUAGCU
AGAAUUACUAUGUAAUCGA
90 45 45 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3517 CUUAAUGAUACAUUAGCUU
GAAUUACUAUGUAAUCGAA
41 20 21 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3518 UUAAUGAUACAUUAGCUUC
AAUUACUAUGUAAUCGAAG
60 20 40 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3519 UAAUGAUACAUUAGCUUCC
AUUACUAUGUAAUCGAAGG
90 0 90 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3520 AAUGAUACAUUAGCUUCCU
UUACUAUGUAAUCGAAGGA
88 10 78 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3521 AUGAUACAUUAGCUUCCUA
UACUAUGUAAUCGAAGGAU
92 0 92 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3522 UGAUACAUUAGCUUCCUAC
ACUAUGUAAUCGAAGGAUG
90 56 34 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3523 GAUACAUUAGCUUCCUACC
CUAUGUAAUCGAAGGAUGG
30 20 10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3524 AUACAUUAGCUUCCUACCU
UAUGUAAUCGAAGGAUGGA
10 25 -15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3525 UACAUUAGCUUCCUACCUG
AUGUAAUCGAAGGAUGGAC
20 30 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3526 ACAUUAGCUUCCUACCUGG
UGUAAUCGAAGGAUGGACC
60 30 30 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3527 CAUUAGCUUCCUACCUGGA
GUAAUCGAAGGAUGGACCU
36 30 6 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254