ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1886 | UCUCCUGGUGAAGCUUGUC AGAGGACCACUUCGAACAG |
40 | 22 | 18 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 | ||
aspsirna1887 | CUCCUGGUGAAGCUUGUCG GAGGACCACUUCGAACAGC |
40 | 25 | 15 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 | ||
aspsirna1888 | UCCUGGUGAAGCUUGUCGU AGGACCACUUCGAACAGCA |
52 | 40 | 12 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 | ||
aspsirna1889 | CCUGGUGAAGCUUGUCGUC GGACCACUUCGAACAGCAG |
47 | 18 | 29 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 | ||
aspsirna1890 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
57 | 2 | 55 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 | ||
aspsirna1891 | UGGUGAAGCUUGUCGUCCC ACCACUUCGAACAGCAGGG |
58 | 10 | 48 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 | ||
aspsirna1892 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
65 | 15 | 50 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 | ||
aspsirna1893 | UGGUGAAGCUUGUCGUCCC ACCACUUCGAACAGCAGGG |
58 | 1 | 57 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 | ||
aspsirna1894 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
60 | 15 | 45 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 | ||
aspsirna1895 | UGGUGAAGCUUGUCGUCCC ACCACUUCGAACAGCAGGG |
60 | 11 | 49 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |