ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1896 | AGGGCCUGUGUCACCCUCAGG UCCCGGACACAGUGGGAGUCC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1897 | GGGCCUGUGUCACCCUCAGGU CCCGGACACAGUGGGAGUCCA |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1898 | GGCCUGUGUCACCCUCAGGUG CCGGACACAGUGGGAGUCCAC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1899 | GCCUGUGUCACCCUCAGGUGA CGGACACAGUGGGAGUCCACU |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1900 | CCUGUGUCACCCUCAGGUGAG GGACACAGUGGGAGUCCACUC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1901 | CUGUGUCACCCUCAGGUGAGG GACACAGUGGGAGUCCACUCC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1902 | UGUGUCACCCUCAGGUGAGGG ACACAGUGGGAGUCCACUCCC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1903 | GUGUCACCCUCAGGUGAGGGU CACAGUGGGAGUCCACUCCCA |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1904 | UGUCACCCUCAGGUGAGGGUG ACAGUGGGAGUCCACUCCCAC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1905 | GUCACCCUCAGGUGAGGGUGG CAGUGGGAGUCCACUCCCACC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1906 | UCACCCUCAGGUGAGGGUGGG AGUGGGAGUCCACUCCCACCC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1907 | CACCCUCAGGUGAGGGUGGGG GUGGGAGUCCACUCCCACCCC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1908 | ACCCUCAGGUGAGGGUGGGGA UGGGAGUCCACUCCCACCCCU |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1909 | CCCUCAGGUGAGGGUGGGGAC GGGAGUCCACUCCCACCCCUG |
78 | 70 | 8 | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1910 | CCUCAGGUGAGGGUGGGGACC GGAGUCCACUCCCACCCCUGG |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1911 | CUCAGGUGAGGGUGGGGACCG GAGUCCACUCCCACCCCUGGC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1912 | UCAGGUGAGGGUGGGGACCGA AGUCCACUCCCACCCCUGGCU |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 | ||
aspsirna1913 | CCCUCAGGUGAGGGUGGGGAC GGGAGUCCACUCCCACCCCUG |
78 | 70 | 8 | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 |