ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3047 | ACUCAGCUGUACACGGACU UGAGUCGACAUGUGCCUGA |
35 | 45 | -10 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3048 | CUCAGCUGUACACGGACUG GAGUCGACAUGUGCCUGAC |
20 | 10 | 10 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3049 | UCAGCUGUACACGGACUGC AGUCGACAUGUGCCUGACG |
45 | 40 | 5 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3050 | CAGCUGUACACGGACUGCA GUCGACAUGUGCCUGACGU |
45 | 35 | 10 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3051 | AGCUGUACACGGACUGCAC UCGACAUGUGCCUGACGUG |
55 | 40 | 15 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3052 | GCUGUACACGGACUGCACG CGACAUGUGCCUGACGUGC |
60 | 12 | 48 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3053 | CUGUACACGGACUGCACGG GACAUGUGCCUGACGUGCC |
20 | 35 | -15 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3054 | UGUACACGGACUGCACGGA ACAUGUGCCUGACGUGCCU |
60 | 44 | 16 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3055 | GUACACGGACUGCACGGAG CAUGUGCCUGACGUGCCUC |
58 | 10 | 48 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3056 | UACACGGACUGCACGGAGA AUGUGCCUGACGUGCCUCU |
62 | 15 | 47 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3057 | ACACGGACUGCACGGAGAA UGUGCCUGACGUGCCUCUU |
65 | 35 | 30 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3058 | CACGGACUGCACGGAGAAG GUGCCUGACGUGCCUCUUC |
80 | 50 | 30 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3059 | ACGGACUGCACGGAGAAGC UGCCUGACGUGCCUCUUCG |
60 | 20 | 40 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3060 | CGGACUGCACGGAGAAGCU GCCUGACGUGCCUCUUCGA |
60 | 20 | 40 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3061 | GGACUGCACGGAGAAGCUG CCUGACGUGCCUCUUCGAC |
70 | 62 | 8 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3062 | GACUGCACGGAGAAGCUGA CUGACGUGCCUCUUCGACU |
50 | 42 | 8 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3063 | ACUGCACGGAGAAGCUGAG UGACGUGCCUCUUCGACUC |
45 | 40 | 5 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3064 | CUGCACGGAGAAGCUGAGG GACGUGCCUCUUCGACUCC |
50 | 30 | 20 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3065 | UGCACGGAGAAGCUGAGGC ACGUGCCUCUUCGACUCCG |
65 | 75 | -10 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3066 | UGUACACGGACUGCACGGA ACAUGUGCCUGACGUGCCU |
20 | 0 | 20 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3067 | CGGACUGCACGGAGAAGCU GCCUGACGUGCCUCUUCGA |
50 | 10 | 40 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3068 | GACUGCACGGAGAAGCUGA CUGACGUGCCUCUUCGACU |
30 | 5 | 25 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 | ||
aspsirna3069 | CGGACUGCACGGAGAAGCU GCCUGACGUGCCUCUUCGA |
50 | 10 | 40 | TGFBI | Lattice corneal dystrophy type I (LCDI) | c.370C>T,p.Arg124Cys | rs12190921 |