Total number of Results for EP1567539B1 are 11
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna3558 UGGAGACUUGCGCAAUGUG
ACCUCUGAACGCGUUACAC		 80 10 70 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
EP1567539B1
aspsirna3559 GGAGACUUGCGCAAUGUGA
CCUCUGAACGCGUUACACU		 76 12 64 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
EP1567539B1
aspsirna3560 GAGACUUGCGCAAUGUGAC
CUCUGAACGCGUUACACUG		 96 13 83 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
EP1567539B1
aspsirna3561 UGGAGACUUGCGCAAUGUG
ACCUCUGAACGCGUUACAC		 90 10 80 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
EP1567539B1
aspsirna3562 GGAGACUUGCGCAAUGUGA
CCUCUGAACGCGUUACACU		 80 20 60 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
EP1567539B1
aspsirna3563 GAGACUUGCGCAAUGUGAC
CUCUGAACGCGUUACACUG		 96 23 73 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
EP1567539B1
aspsirna3564 UGGAGACUUGCGCAAUGUG
ACCUCUGAACGCGUUACAC		 90 28 62 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
EP1567539B1
aspsirna3565 GGAGACUUGCGCAAUGUGA
CCUCUGAACGCGUUACACU		 88 18 70 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
EP1567539B1
aspsirna3566 GAGACUUGCGCAAUGUGAC
CUCUGAACGCGUUACACUG		 96 13 83 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
EP1567539B1
aspsirna3567 GACAAAGAUGCUGUGGCCGAU
CUGUUUCUACGACACCGGCUA		 87 20 67 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.281G>C (p.Gly94Ala) rs12191243
EP1567539B1
aspsirna3568 GACAAAGAUGCUGUGGCCGAU
CUGUUUCUACGACACCGGCUA		 87 20 67 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.281G>C (p.Gly94Ala) rs12191243
EP1567539B1