Total number of Results for US8859752B2 are 8
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna3569 UGGCUCACCAGAUUACACU
ACCGAGUGGUCUAAUGUGA
60 20 40 ACVR1 Fibrodysplasia Ossificans Progressiva (FOP) c.617G>A,p.Arg206His rs12191267
US8859752B2
aspsirna3570 GUGGCUCACCAGAUUACAC
CACCGAGUGGUCUAAUGUG
45 10 35 ACVR1 Fibrodysplasia Ossificans Progressiva (FOP) c.617G>A,p.Arg206His rs12191267
US8859752B2
aspsirna3571 AGUGGCUCACCAGAUUACA
UCACCGAGUGGUCUAAUGU
60 20 40 ACVR1 Fibrodysplasia Ossificans Progressiva (FOP) c.617G>A,p.Arg206His rs12191267
US8859752B2
aspsirna3572 CAGUGGCUCACCAGAUUAC
GUCACCGAGUGGUCUAAUG
75 33 42 ACVR1 Fibrodysplasia Ossificans Progressiva (FOP) c.617G>A,p.Arg206His rs12191267
US8859752B2
aspsirna3573 ACAGUGGCUCACCAGAUUA
UGUCACCGAGUGGUCUAAU
50 20 30 ACVR1 Fibrodysplasia Ossificans Progressiva (FOP) c.617G>A,p.Arg206His rs12191267
US8859752B2
aspsirna3574 AACAGUGGCUCACCAGAUU
UUGUCACCGAGUGGUCUAA
60 39 21 ACVR1 Fibrodysplasia Ossificans Progressiva (FOP) c.617G>A,p.Arg206His rs12191267
US8859752B2
aspsirna3575 CAGUGGCUCACCAGAUUAA
GUCACCGAGUGGUCUAAUU
45 20 25 ACVR1 Fibrodysplasia Ossificans Progressiva (FOP) c.617G>A,p.Arg206His rs12191267
US8859752B2
aspsirna3576 CAGUGGCUCACCAGAUUAG
GUCACCGAGUGGUCUAAUC
68 14 54 ACVR1 Fibrodysplasia Ossificans Progressiva (FOP) c.617G>A,p.Arg206His rs12191267
US8859752B2