ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3404 | UCCAAGAUGGACGGCCGCUCA AGGUUCUACCUGCCGGCGAGU |
42 | 50 | -8 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3405 | CCAAGAUGGACGGCCGCUCAG GGUUCUACCUGCCGGCGAGUC |
40 | 40 | 0 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3406 | AGAUGGACGGCCGCUCAGGUU UCUACCUGCCGGCGAGUCCAA |
40 | 50 | -10 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3407 | AUGGACGGCCGCUCAGGUUCU UACCUGCCGGCGAGUCCAAGA |
35 | 40 | -5 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3408 | GACGGCCGCUCAGGUUCUGCU CUGCCGGCGAGUCCAAGACGA |
42 | 51 | -9 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3409 | CGGCCGCUCAGGUUCUGCUUU GCCGGCGAGUCCAAGACGAAA |
45 | 35 | 10 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3410 | GUGCUGAGCGGCGCCGCGAGU CACGACUCGCCGCGGCGCUCA |
50 | 45 | 5 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3411 | CGCCGCGAGUCGGCCCGAGGC GCGGCGCUCAGCCGGGCUCCG |
60 | 50 | 10 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3412 | ACCGCCAUGGCGACCCUGGAA UGGCGGUACCGCUGGGACCUU |
60 | 45 | 15 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3413 | CCGCCAUGGCGACCCUGGAAA GGCGGUACCGCUGGGACCUUU |
50 | 40 | 10 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3414 | GAAGGCCUUCGAGUCCCUCAA CUUCCGGAAGCUCAGGGAGUU |
45 | 50 | -5 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3415 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
65 | 61 | 4 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3416 | CCGCCGCCGCCUCCUCAGCUU GGCGGCGGCGGAGGAGUCGAA |
60 | 55 | 5 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3417 | GCCGCCUCCUCAGCUUCCUCA CGGCGGAGGAGUCGAAGGAGU |
55 | 45 | 10 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3418 | UCAGCCGCCGCCGCAGGCACA AGUCGGCGGCGGCGUCCGUGU |
57 | 41 | 16 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3419 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
56 | 34 | 22 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3420 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
60 | 33 | 27 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3421 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
45 | 30 | 15 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3422 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
40 | 33 | 7 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3423 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
33 | 20 | 13 | Huntington disease (HD) | (CAG)n | NA | |||
aspsirna3424 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
20 | 10 | 10 | HTT | Huntington disease (HD) | (CAG)n | NA | ||
aspsirna3425 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
11 | 0 | 11 | Huntington disease (HD) | (CAG)n | NA | |||
aspsirna3426 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
32 | 0 | 32 | HTT | Huntington disease (HD) | (CAG)n | NA |