ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3383 | UCCAAGAUGGACGGCCGCUCA AGGUUCUACCUGCCGGCGAGU |
1 | 0 | 1 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3384 | CCAAGAUGGACGGCCGCUCAG GGUUCUACCUGCCGGCGAGUC |
0 | 0 | 0 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3385 | AGAUGGACGGCCGCUCAGGUU UCUACCUGCCGGCGAGUCCAA |
0 | 0 | 0 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3386 | AUGGACGGCCGCUCAGGUUCU UACCUGCCGGCGAGUCCAAGA |
0 | 0 | 0 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3387 | GACGGCCGCUCAGGUUCUGCU CUGCCGGCGAGUCCAAGACGA |
0 | 0 | 0 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3388 | CGGCCGCUCAGGUUCUGCUUU GCCGGCGAGUCCAAGACGAAA |
0 | 0 | 0 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3389 | GUGCUGAGCGGCGCCGCGAGU CACGACUCGCCGCGGCGCUCA |
0 | 0 | 0 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3390 | CGCCGCGAGUCGGCCCGAGGC GCGGCGCUCAGCCGGGCUCCG |
0 | 0 | 0 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3391 | ACCGCCAUGGCGACCCUGGAA UGGCGGUACCGCUGGGACCUU |
0 | 0 | 0 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3392 | CCGCCAUGGCGACCCUGGAAA GGCGGUACCGCUGGGACCUUU |
20 | 30 | -10 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3393 | GAAGGCCUUCGAGUCCCUCAA CUUCCGGAAGCUCAGGGAGUU |
0 | 10 | -10 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3394 | CUUCGAGUCCCUCAAGUCCUU GAAGCUCAGGGAGUUCAGGAA |
70 | 50 | 20 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3395 | CCGCCGCCGCCUCCUCAGCUU GGCGGCGGCGGAGGAGUCGAA |
20 | 33 | -13 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3396 | GCCGCCUCCUCAGCUUCCUCA CGGCGGAGGAGUCGAAGGAGU |
30 | 40 | -10 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3397 | UCAGCCGCCGCCGCAGGCACA AGUCGGCGGCGGCGUCCGUGU |
42 | 33 | 9 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3398 | GCCGCAGGCACAGCCGCUGCU CGGCGUCCGUGUCGGCGACGA |
20 | 11 | 9 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3399 | GGCACAGCCGCUGCUGCCUCA CCGUGUCGGCGACGACGGAGU |
23 | 13 | 10 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3400 | GCCGCUGCUGCCUCAGCCGCA CGGCGACGACGGAGUCGGCGU |
22 | 33 | -11 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3401 | CGGCCCGGCUGUGGCUGAGGA GCCGGGCCGACACCGACUCCU |
20 | 40 | -20 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3402 | CUGUGGCUGAGGAGCCGCUGC GACACCGACUCCUCGGCGACG |
13 | 33 | -20 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA | ||
aspsirna3403 | UGUGGCUGAGGAGCCGCUGCA ACACCGACUCCUCGGCGACGU |
20 | 20 | 0 | HTT | Huntington disease (HD) | Targeting on exon 1 | NA |