ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0084 | GUAAGCUAAAAACCAACAU CAUUCGAUUUUUGGUUGUA |
57 | 88 | -31 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0085 | AGUAAGCUAAAAACCAACA UCAUUCGAUUUUUGGUUGU |
60 | 63 | -3 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0086 | GAGUAAGCUAAAAACCAAC CUCAUUCGAUUUUUGGUUG |
27 | 96 | -69 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0087 | CCGAGUAAGCUAAAAACCA GGCUCAUUCGAUUUUUGGU |
84 | 92 | -8 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0088 | GCCGAGUAAGCUAAAAACC CGGCUCAUUCGAUUUUUGG |
74 | 87 | -13 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0104 | CGAGUAAGCUAAAAACCAA GCUCAUUCGAUUUUUGGUU |
86 | 98 | -12 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0105 | CGAGAAAGCUAAAAACCAA GCUCUUUCGAUUUUUGGUU |
87 | 99 | -12 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0106 | CGAGUUAGCUAAAAACCAA GCUCAAUCGAUUUUUGGUU |
84 | 99 | -15 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0107 | CGAGUAACCUAAAAACCAA GCUCAUUGGAUUUUUGGUU |
79 | 99 | -20 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0108 | CGAGUAAGCUAUAAACCAA GCUCAUUCGAUAUUUGGUU |
67 | 99 | -32 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0109 | CGAGUAAGCUAAUAACCAA GCUCAUUCGAUUAUUGGUU |
20 | 99 | -79 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0110 | CGAGUAAGCUAAAUACCAA GCUCAUUCGAUUUAUGGUU |
82 | 99 | -17 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0111 | CGAGUAAGCUAAAAUCCAA GCUCAUUCGAUUUUAGGUU |
36 | 99 | -63 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0112 | CGAGUAAGCUAAAAAGCAA GCUCAUUCGAUUUUUCGUU |
39 | 99 | -60 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0113 | CGAGUAAGCUAAAAACGAA GCUCAUUCGAUUUUUGCUU |
0 | 99 | -99 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0143 | CGAGUAAGCUAAAAACCAA GCUCAUUCGAUUUUUGGUU |
86 | 98 | -12 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0144 | CGAGAAAGCUAAAAACCAA GCUCUUUCGAUUUUUGGUU |
87 | 99 | -12 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0145 | CGAGUUAGCUAAAAACCAA GCUCAAUCGAUUUUUGGUU |
84 | 99 | -15 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0146 | CGAGUAACCUAAAAACCAA GCUCAUUGGAUUUUUGGUU |
79 | 99 | -20 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0147 | CGAGUAAGCUAUAAACCAA GCUCAUUCGAUAUUUGGUU |
67 | 99 | -32 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0148 | CGAGUAAGCUAAUAACCAA GCUCAUUCGAUUAUUGGUU |
20 | 99 | -79 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0149 | CGAGUAAGCUAAAUACCAA GCUCAUUCGAUUUAUGGUU |
82 | 99 | -17 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0150 | CGAGUAAGCUAAAAUCCAA GCUCAUUCGAUUUUAGGUU |
36 | 99 | -63 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0151 | CGAGUAAGCUAAAAAGCAA GCUCAUUCGAUUUUUCGUU |
39 | 99 | -60 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna0152 | CGAGUAAGCUAAAAACGAA GCUCAUUCGAUUUUUGCUU |
0 | 99 | -99 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna3499 | GUAAGCUAAAAACCAACAU CAUUCGAUUUUUGGUUGUA |
60 | 88 | -28 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna3500 | AGUAAGCUAAAAACCAACA UCAUUCGAUUUUUGGUUGU |
60 | 63 | -3 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna3501 | GAGUAAGCUAAAAACCAAC CUCAUUCGAUUUUUGGUUG |
27 | 96 | -69 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna3502 | CCGAGUAAGCUAAAAACCA GGCUCAUUCGAUUUUUGGU |
84 | 92 | -8 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |
|
aspsirna3503 | GCCGAGUAAGCUAAAAACC CGGCUCAUUCGAUUUUUGG |
74 | 87 | -13 | PRNP | Prion disease/Gerstmann-Straussler disease | c.314C>T,p.Pro105Leu | rs11538758 | ![]() |