ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1800 | UCAAGACCCUC---AACAAGUU AGUUCUGGGAG---UUGUUCAA |
75 | 20 | 55 | KRT6a | Pachyonychia congenita (PC) | c.514_516delAAC,p.Asn172del | rs26760745 | ![]() |
|
aspsirna1801 | CAAGACCCUC---AACAAGUUU GUUCUGGGAG---UUGUUCAAA |
30 | 20 | 10 | KRT6a | Pachyonychia congenita (PC) | c.514_516delAAC,p.Asn172del | rs26760745 | ![]() |
|
aspsirna1802 | AAGACCCUC---AACAAGUUUG UUCUGGGAG---UUGUUCAAAC |
25 | 5 | 20 | KRT6a | Pachyonychia congenita (PC) | c.514_516delAAC,p.Asn172del | rs26760745 | ![]() |