Predicted Off-targets for siRNA "ggaaccucuauguaucccu" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

1 hit was found for GGAACCUCUAUGUAUCCCU (0 guide strand hits and 1 sense strand hits.)

Hits to Sense strand


AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_206933 USH2A 5261 5279 uGGGAUAuAUAcAGGUUCC2 3 7   false   <90%   18883


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1567
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_001077484SLC38A13
NM_030674SLC38A13
NM_030806C1orf213
NM_174929ZMIZ23
NM_031449ZMIZ23
NM_203329CD593
NM_203331CD593
NM_203330CD593
NM_000611CD593
NM_021615CHST63
NM_012193FZD43
NM_133493CD1093
NM_000555DCX3
NM_178152DCX3
NM_178153DCX3
NM_178151DCX3
NM_005197CHES13
NM_0010854713
NM_004448ERBB23
NM_001005862ERBB23
NM_016206VGLL32
NM_024989PGAP12
NM_0010099842
NM_001032731OAS22
NM_006359SLC9A62
NM_001042537SLC9A62
NM_153711FAM26E2
NM_015092SMG12
NM_001079843CASZ12
XM_931376SETD52
XM_944260SETD52
XM_931478SETD52
XM_944280SETD52
XM_931417SETD52
XM_944276SETD52
XM_939712SETD52
NM_001080517SETD52
XM_944303SETD52
XM_931455SETD52
XM_931447SETD52
XM_944298SETD52
XM_944295SETD52
XM_931444SETD52
NM_003044SLC6A122
NM_173830C6orf1822
NM_001083535C6orf1822
NM_033394TANC12
NM_198461LONRF22
NM_006420ARFGEF22
NM_001006641SLC25A252
NM_001006642SLC25A252
NM_052901SLC25A252
NM_001006643SLC25A252
NM_014505KCNMB42
NM_145333MAP3K72
NM_145331MAP3K72
NM_145332MAP3K72
NM_003188MAP3K72
NM_002760PRKY2
NM_004976KCNC12
NM_000599IGFBP52
NM_000382ALDH3A22
NM_001031806ALDH3A22
NM_001042669ARHGAP242
NM_001025616ARHGAP242
NM_031305ARHGAP242
XM_001132951LOC3395352
XM_001132766LOC3395352
NM_020184CNNM42
NM_014653WSCD22
NM_015143METAP12
NM_000990RPL27A2
NM_001010898SLC6A172
NM_016579CD3202
NM_212467CAPN32
NM_012316KPNA62
NM_001029864KIAA17552
NM_006361HOXB132
NM_014630ZNF5922
NM_001975ENO22
NM_015227POFUT22
NM_000386BLMH2
NM_001008860NIPA22
NM_001008894NIPA22
NM_001008892NIPA22
NM_030922NIPA22
NM_001009992ZNF6482
NM_025136OPA32
XM_927029PPP1R3E2
XM_940069PPP1R3E2
NM_033221TRIM142
NM_014788TRIM142
NM_145043NEIL22
NM_015471NSL12
NM_001042549NSL12
NM_022658HOXC82
NM_004262TMPRSS11D2
NM_004852ONECUT22
NM_003648DGKD2
NM_152879DGKD2
NM_006426DPYSL42
NM_172388NFATC12
NM_006162NFATC12
NM_172389NFATC12
NM_172387NFATC12
NM_033100PCDH212
NM_012325MAPRE12
NM_005026PIK3CD2
NM_001038707CDC42SE12
NM_020239CDC42SE12
NM_033133CNP2
NM_015395DKFZP434B03352
NM_182511CBLN22
NM_0011055792
NM_020133AGPAT42
NM_024577SH3TC22
NM_006371CRTAP2
NM_007084SOX212
NM_014504RABGEF12
NM_015064ERC12
NM_178039ERC12
NM_178040ERC12
NM_178038ERC12
NM_178037ERC12
NM_015338ASXL12
XM_934649C1orf342
XM_945958C1orf342
NM_017665ZCCHC101
NM_173545C2orf131
NM_182481BAGE31
NM_182484BAGE51
NM_182482BAGE21
NM_181704BAGE41
NM_024546C13orf71
NM_033296MRFAP11
NM_133265AMOT1
NM_017544NKRF1
NM_014322OPN31
NM_031216SEH1L1
NM_001013437SEH1L1
NM_019083CCDC761
XM_938413PRAMEF31
NM_0010998501
NM_0010997901
NM_001013692PRAMEF31
NM_001017967MARVELD31
NM_178191ATPIF11
XM_001130638LOC7283941
XM_001132666LOC7313251
XM_926071LOC6425921
NM_0010996921
NM_198581ZC3H61
NM_182572ZSCAN11
NM_173689CRB21
NM_058169LOH12CR11
NM_018225SMU11
NM_007271STK381
NM_001044387ZNF5571
NM_024341ZNF5571
NM_001044388ZNF5571
NM_207387C17orf761
NM_014925R3HDM21
NM_031474NRIP21
NM_021905GABBR11
NM_183065TMEM1071
NM_032354TMEM1071
NM_017824MARCH51
NM_004364CEBPA1
NM_174978C14orf391
NM_032492JAGN11
NM_006754SYPL11
NM_182715SYPL11
NM_021155CD2091
NM_003758EIF3S11
NM_017921NPLOC41
NM_020989CRYGC1
NM_198596SULF21
NM_018837SULF21
NM_006210PEG31
NM_017919STX171
NM_182688UBE2G21
NM_003343UBE2G21
NM_005158ABL21
NM_007314ABL21
NM_0011001081
NM_001079910LRRIQ11
XM_001131275LOC7319251
NM_022445TPK11
NM_001042482TPK11
NM_006469IVNS1ABP1
NM_015216HISPPD11
NM_000337SGCD1
NM_022073EGLN31
NM_030762BHLHB31
NM_000042APOH1
NM_015076CDC2L61
NM_017740ZDHHC71
NM_017924C14orf1191
NM_014345ZNF3181
NM_025152NUBPL1
NM_205852CLEC12B1
NM_006803AP3M21
NM_178129P2RY81
NM_016143NSFL1C1
NM_182483NSFL1C1
NM_018839NSFL1C1
NM_0155661
NM_019098CNGB31
NM_005819STX61
NM_001039523CHRNA11
NM_000079CHRNA11
NM_001552IGFBP41
NM_004259RECQL51
NM_001692ATP6V1B11
NM_030643APOL41
NM_145660APOL41
NM_001010922C1orf1781
NM_032515BOK1
NM_153688ZFP11
NM_001480GALR11
NM_017688BSPRY1
NM_153810C10orf461
NM_003672CDC14A1
XM_001132119LOC2574071
XM_001129456LOC2574071
NM_173667FLJ375431
NM_018640LMO31
NM_001001395LMO31
NM_019050USP531
NM_017681NUP62CL1
NM_207647FSD1L1
NM_022648TNS11
NM_033505SELI1
NM_138348FAM105B1
NM_0147221
NM_002440MSH41
NM_001039840CHIC11
NM_001040628NCALD1
NM_001040626NCALD1
NM_001040625NCALD1
NM_032041NCALD1
NM_001040629NCALD1
NM_001040624NCALD1
NM_001040627NCALD1
NM_001040630NCALD1
NM_001032394GPR1261
NM_020455GPR1261
NM_198569GPR1261
NM_001032395GPR1261
NM_015657ABCA121
NM_173076ABCA121
NM_003679KMO1
NM_001001709FLJ455371
NM_004623TTC41
NM_201431RASSF61
NM_177532RASSF61
NM_020122KCMF11
NM_025191EDEM31
NM_004760STK17A1
NM_004739MTA21
NM_000141FGFR21
NM_022970FGFR21
NM_006927ST3GAL21
NM_015178RHOBTB21
NM_007078LDB31
NM_001080114LDB31
NM_001440EXTL31
NM_006106YAP11
NM_014899RHOBTB31
NM_003393WNT8B1
NM_030792GDPD51
NM_001077628APH1A1
NM_016022APH1A1
NM_007219RNF241
NM_006306SMC1A1
NM_0010997841
XM_938374LOC6440101
NM_017575SMG61
NM_005957MTHFR1
XM_946142SHANK31
NM_001080420SHANK31
NM_206818OSCAR1
NM_014942ANKRD61
NM_000839GRM21
NM_138473SP11
NM_001024858SPTB1
NM_016484PDZD111
NM_173598KSR21
NM_014381MLH31
NM_001040108MLH31
NM_022725FANCF1
NM_014830ZBTB391
NM_012287CENTB21
NM_001939DRP21
XM_001130722LOC7317691
XM_001127289LOC7283531
NM_000598IGFBP31
NM_001013398IGFBP31
NM_004673ANGPTL11
NM_020309SLC17A71
NM_016353ZDHHC21
NM_022351EFCBP11
NM_015257KIAA02861
NM_144573NEXN1
NM_021199SQRDL1
NM_030579CYB5B1
NM_002223ITPR21
NM_144607CYB5D11
NM_001040458ARTS-11
NM_002711PPP1R3A1
NM_1526341
NM_012320LYPLA31
NM_001012393OPCML1
NM_002545OPCML1
NM_004249RAB281
NM_003762VAMP41
NM_003255TIMP21
XM_001132362TIMP21
NM_014766SCRN11
XM_940609FLJ250761
XM_059689FLJ250761
XM_001128906LOC7287821
XM_001126278LOC7305591
XM_001128311LOC7314491
XM_001129750LOC7289991
XM_001126420LOC7305761
XM_001126432LOC7280501
NM_005353ITGAD1
NM_015509NECAP11
NM_017599VEZT1
NM_145176SLC2A121
NM_002430MN11
XM_945302LOC6522251
XM_934407LOC6471311
NM_022465IKZF41
NM_000818GAD21
NM_002783PSG71
NM_001024809RARA1
NM_000964RARA1
NM_020909EPB41L51
NM_176880TRA161
NM_030911CDADC11
NM_005119THRAP31
NM_207333ZNF3201
NM_012146DUX11
NM_006869CENTA11
NM_173502PRSS361
NM_198849LOC2835141
NM_001080498EMR41
NM_152404UGT3A11
NM_020348CNNM11
NM_198219ING11
NM_198218ING11
NM_005537ING11
NM_198217ING11
NM_032342C9orf1251
NM_004747DLG51
NM_032828ZNF5871
NM_152475ZNF4171
NM_144967FLJ300581
NM_178425HDAC91
NM_178423HDAC91
NM_182663RASSF51
NM_182664RASSF51
NM_182665RASSF51
NM_0122741
NM_194286KIAA18531
NM_002959SORT11
NM_020407RHBG1
NM_0146871
NM_147202C9orf251
NM_013365GGA11
NM_001001560GGA11
NM_0208401
NM_001199BMP11
NM_006128BMP11
NM_144775SMCR81
NM_002471MYH61
NM_0011112831
NM_000618IGF11
NM_0011112841
NM_182767SLC6A151
NM_017510TMED91
NM_002015FOXO1A1
NM_198580SLC27A11
NM_015073SIPA1L31
NM_144580C1orf851
NM_020369FSCN31
NM_012255XRN21
NM_012483GNLY1
NM_006433GNLY1
NM_020657ZNF3041
NM_007137ZNF811
NM_005934MLLT11
NM_002205ITGA51
NM_0059211
XM_929931LOC6534891
NM_005054RGPD51
XM_001126221LOC7278511
XM_001126260LOC7278511
XM_001133591LOC7295401
XM_001133590LOC7295401
XM_001126233LOC7278511
XM_001126248LOC7278511
XM_001126272LOC7278511
NM_014635GCC21
NM_181453GCC21
NM_013364PNMA31
NM_153188TNPO11
NM_002270TNPO11
NM_000453SLC5A51
NM_0146921
NM_145804ABTB21
NM_212555C11orf381
XM_001133431LOC7292301
NM_000648CCR21
NM_012121CDC42EP41
NM_001083603PTCH11
NM_001083607PTCH11
NM_001083602PTCH11
NM_001083605PTCH11
NM_001083606PTCH11
NM_001083604PTCH11
NM_000264PTCH11
NM_001905CTPS1
NM_212551LYSMD11
NM_001005920LOC3391231
NM_012164FBXW21
NM_174934SCN4B1
XM_001132419SLC35F31
NM_173508SLC35F31
NM_032242PLXNA11
NM_003370VASP1
NM_012406PRDM41
NM_015621CCDC691
NM_033044MACF11
NM_012090MACF11
NM_020777SORCS21
NM_0010976401
NM_0010976391
NM_0010976411
NM_000149FUT31
NM_152835PDIK1L1
NM_032683FKSG241
NM_175736FMNL31
NM_198900FMNL31
NM_133374ZNF6181
NM_0010994031
NM_020226PRDM81
NM_016544RBJ1
NM_0011026511
NM_003486SLC7A51
NM_020919ALS21
NM_001040701FUT61
NM_000150FUT61
NM_001010911C10orf1141
XM_928199LOC4005811
NM_144629RFTN21
NM_002832PTPN71
NM_080588PTPN71
NM_033274ADAM191
NM_145059FUK1
NM_022064RNF1231
NM_003074SMARCC11
NM_199487C20orf441
NM_018244C20orf441
NM_006526ZNF2171
NM_177401MIDN1
NM_021962ABR1
NM_001092ABR1
NM_080669SLC46A11
NM_020384CLDN21
NM_018999KIAA11281
NM_015094HIC21
NM_004936CDKN2B1
NM_078487CDKN2B1
NM_017540GALNT101
NM_198321GALNT101
NM_020702KIAA11611
NM_130799MEN11
NM_130801MEN11
NM_000244MEN11
NM_130803MEN11
NM_130800MEN11
NM_130804MEN11
NM_130802MEN11
NM_058163TSR21
NM_145298APOBEC3F1
NM_005226EDG31
NM_001040167LFNG1
NM_183059RD31
NM_018953HOXC51
NM_001080530LOC920171
NM_018553C17orf851
NM_017882CLN61
NM_003983SLC7A61
NM_001076785SLC7A61
NM_001001664LOC3397451
NM_001558IL10RA1
NM_032449CC2D1B1
NM_020778ALPK31
NM_033337CAV31
NM_001234CAV31
NM_021965PGM51
NM_014762DHCR241
NM_001897CSPG41
NM_002833PTPN91
XM_001128975PTPN91
NM_001012264RNASE131
NM_174892CD300LB1
NM_015331NCSTN1
NM_130469JDP21
NM_182587C2orf211
NM_002030FPRL21
NM_005822DSCR1L11
NM_017563IL17RD1
NM_001080973IL17RD1
NM_144628TBC1D201
NM_001025252TPD521
NM_001025253TPD521
NM_005079TPD521
NM_173511ALS2CR131
NM_182687PKMYT11
NM_005801EIF11
NM_000632ITGAM1
NM_130468CHST141
NM_014747RIMS31
NM_001014435CA71
NM_005182CA71
NM_019856MYOM11
NM_003803MYOM11
NM_058181C21orf571
NM_017423GALNT71
NM_152623CDC20B1
NM_198476C19orf541
NM_199129Kua1
NM_014212HOXC111
NM_0010987901
NM_021242MID1IP11
NM_0010987911
NM_032980DTNA1
NM_001390DTNA1
NM_032975DTNA1
NM_178502DTX31
NM_015627LDLRAP11
NM_015340LARS21
NM_173832ZFP411
NM_002444MSN1
NM_018659CYTL11
NM_0010992701
XM_927284DKFZP781G01191
XM_936878DKFZP781G01191
XM_941783JMJD31
NM_001080424JMJD31
NM_007232HRH31
NM_000926PGR1
NM_022836DCLRE1B1
NM_152998EZH21
NM_004456EZH21
NM_031463HSDL11
NM_015052HECW11
NM_144604NHN11
NM_033426KIAA17371
NM_030912TRIM81
NM_194457UBE2J21
NM_194315UBE2J21
NM_058167UBE2J21
NM_194458UBE2J21
NM_022459XPO41
NM_001050SSTR21
NM_014861ATP2C21
NM_152586USP541
NM_007362NCBP21
NM_001042540NCBP21
NM_014646LPIN21
NM_0010996781
NM_206926SEPN11
NM_020451SEPN11
NM_015879ST8SIA31
NM_024105ALG121
XM_001130627LOC7295591
NM_012232PTRF1
NM_006946SPTBN21
NM_018099MLSTD11
NM_0152971
NM_139014MAPK141
NM_006517SLC16A21
NM_021229NTN41
NM_015242CENTD21
NM_139181CENTD21
NM_001040118CENTD21
NM_005969NAP1L41
NM_003761VAMP81
NM_206909PSD31
NM_015310PSD31
NM_003636KCNAB21
NM_172130KCNAB21
NM_0207001
NM_003407ZFP361
NM_002167ID31
XM_001133002LOC7288041
NM_005063SCD1
NM_001012643LOC3393441
NM_001037293PALM21
NM_053016PALM21
NM_005036PPARA1
NM_001001928PPARA1
NM_000918P4HB1
NM_212464CAPN31
NM_015071ARHGAP261
NM_015520MAGI11
NM_001033057MAGI11
NM_012293PXDN1
NM_004566PFKFB31
NM_030928CDT11
NM_030971SFXN31
NM_018373SYNJ2BP1
NM_032174TOMM40L1
NM_153835GPR1131
NM_016083CNR11
NM_033181CNR11
NM_0011055651
XM_166203SMTNL11
NM_004594SLC9A51
NM_007167ZMYM61
NM_001013693LDLRAD21
NM_153051MTMR31
NM_021090MTMR31
NM_153050MTMR31
NM_001008392CTDSPL1
NM_005808CTDSPL1
NM_032806C3orf391
NM_016176SDF41
NM_016547SDF41
NM_020179C11orf751
NM_181521CMTM41
NM_002631PGD1
NM_145212MRPL301
NM_145799SEPT61
NM_001083913C10orf261
NM_017787C10orf261
NM_002074GNB11
NM_001024227ARF11
NM_001658ARF11
NM_001024228ARF11
NM_001024226ARF11
NM_003462DNALI11
NM_017719SNRK1
NM_0011005941
NM_017668NDE11
NM_017488ADD21
NM_017483ADD21
NM_001617ADD21
NM_002928RGS161
NM_014571HEYL1
NM_174977SEC14L41
XM_926406LOC6430371
XM_936787LOC6430371
NM_021149COTL11
NM_025090USP361
NM_004845PCYT1B1
NM_173354SNF1LK1
NM_020960GPR1071
XM_942899LOC6422091
XM_936630LOC6422091
NM_013358PADI11
XM_933935LOC6467781
XM_943239LOC6467781
XM_001133295LOC7324011
XM_001133210LOC7302401
NM_173493PASD11
NM_000629IFNAR11
NM_021614KCNN21
NM_170775KCNN21
NM_030918SNX271
NM_007293C4A1
NM_001002029C4B1
NM_207119LRRC201
NM_018239LRRC201
NM_018205LRRC201
NM_015059TLN21
NM_006203PDE4D1
NM_0011046311
NM_004578RAB4A1
NM_012334MYO101
NM_005137DGCR21
NM_030891LRRC31
NM_000324RHAG1
NM_1827627A51
NM_080820DTD11
NM_004843IL27RA1
NM_021202TP53INP21
NM_015359SLC39A141
NM_002508NID11
NM_024909C6orf1341
NM_001039905FLJ385961
NM_015912C8ORFK321
NM_004767GPR37L11
NM_005099ADAMTS41
NM_003643GCM11
NM_032503MCHR21
NM_001040179MCHR21
NM_020645NRIP31
NM_018641CHST121
NM_175066DDX511
NM_145051RNF1831
NM_173476CCDC781
NM_032497ZNF5591
NM_004658RASAL11
NM_002081GPC11
NM_004055CAPN51
NM_018376NIPSNAP3B1
NM_030895ZNF6961
NM_145279MOBKL2C1
NM_201403MOBKL2C1
NM_032039ITFG31
NM_207370GPR1531
NM_021133RNASEL1
NM_013279C11orf91
NM_001048209HNT1
NM_016522HNT1
NM_014862ARNT21
NM_148571MRPL271
NM_053023ZFP911
NM_0010984841
NM_003759SLC4A41
NM_014763MRPL191
NM_016453NCKIPSD1
NM_184231NCKIPSD1
NM_001039570KREMEN11
NM_001039571KREMEN11
NM_015831ACHE1
NM_015044GGA21
NM_176786IL9R1
NM_133373PLCD31
NM_004588SCN2B1
NM_014636RALGPS11
NM_177996EPB41L11
NM_012156EPB41L11
NM_022469GREM21
NM_014231VAMP11
NM_199245VAMP11
NM_198935SS18L11
NM_002594PCSK21
NM_016170TLX21
NM_022003FXYD61
NM_000719CACNA1C1
NM_033121ANKRD13A1
NM_024069C19orf501
NM_032151PCBD21
NM_020774MIB11
NM_014937INPP5F1
NM_024792FAM57A1
NM_145351SCARF11
NM_145350SCARF11
NM_145349SCARF11
NM_133637DQX11
NM_022112P53AIP11
NM_182970RIMS41
NM_003566EEA11
NM_018979WNK11
NM_001002909GPATCH81
NM_017759FLJ203091
NM_007210GALNT61
NM_002486NCBP11
XM_001130700LOC7295801
XM_001126751LOC7306721
NM_018647TNFRSF191
NM_017633FAM46A1
NM_013375ABT11
NM_003328TXK1
NM_0010985121
NM_006258PRKG11
NM_032012C9orf51
NM_0010997341
NM_033012TNFSF111
NM_003701TNFSF111
NM_212559XKRX1
XM_001125723LOC7277521
NM_001015070KIR3DP11
NM_020925CACHD11
NM_032037TSSK61
NM_201636TBXA2R1
NM_001060TBXA2R1
NM_001011718XKR71
NM_019106SEPT31
NM_203411TMEM881
NM_024022TMPRSS31
NM_032404TMPRSS31
NM_032401TMPRSS31
NM_003200TCF31
NM_138436C8orf401
NM_004252SLC9A3R11
NM_006661PDE10A1
NM_001001392CD441
NM_015264C22orf91
NM_001009880C22orf91
NM_001527HDAC21
NM_178543ENPP71
NM_001017440CALN11
NM_031468CALN11
NM_015111N4BP31
NM_002401MAP3K31
NM_203351MAP3K31
XM_371663LOC6537121
XM_939842LOC6541411
NM_207397CD164L21
NM_002254KIF3C1
NM_198484ZNF6211
NM_0010984141
NM_014686KIAA03551
NM_182597FLJ395751
NM_002765PRPS21
NM_001039091PRPS21
NM_006005WFS11
NM_000721CACNA1E1
NM_022898BCL11B1
NM_138576BCL11B1
NM_005865PRSS161
NM_001080412ZBTB381
XM_001133510ZBTB381
NM_004319ASTN11
NM_130852PLUNC1
NM_016583PLUNC1
NM_001080485ZNF2751
NM_022737LPPR21
NM_173854SLC41A11
NM_024843CYBRD11
NM_005715UST1
NM_199454PRDM161
NM_022114PRDM161
NM_007050PTPRT1
NM_133170PTPRT1
NM_000076CDKN1C1
NM_001001552LEMD11
NM_003576STK241
NM_001032296STK241
XM_001125827LOC7278201
NM_001042498SLC35A21
NM_001032289SLC35A21
NM_003918GYG21
NM_001079855GYG21
NM_000831GRIK31
NM_203343EPB411
NM_203342EPB411
NM_004437EPB411
NM_004773ZNHIT31
NM_001039503POL3S1
NM_213566DFFA1
NM_005702ERAL11
NM_021961TEAD11
NM_015545PTCD11
NM_144585SLC22A121
NM_153378SLC22A121
NM_017797BTBD21
NM_003198TCEB31
NM_024598C16orf571
NM_015335THRAP21
NM_014952BAHD11
NM_004112FGF111
NM_181491SURF51
NM_006823PKIA1
NM_181839PKIA1
NM_025078PQLC11
NM_001010888ZC3H12B1
NM_021245MYOZ11
NM_004612TGFBR11
NM_016412IGF2AS1
NM_0010986731
NM_021934C12orf441
NM_018484SLC22A111
NM_148172PEMT1
NM_148173PEMT1
NM_007169PEMT1
NM_032141CCDC551
NM_031455CCDC31
NM_016340RAPGEF61
NM_0010122411
NM_005877SF3A11
NM_001005409SF3A11
NM_001077239RNF2141
NM_207343RNF2141
NM_145259ACVR1C1
NM_0011110311
NM_0011110331
NM_0011110321
NM_0010986241
NM_033290MID11
NM_000381MID11
NM_014368LHX61
NM_199160LHX61
NM_198490RAB431
NM_004742MAGI11
NM_001002255SUMO41
XM_001131540LOC6524891
XM_941950LOC6524891
XM_001126213LOC6524891
NM_006937SUMO21
NM_001005849SUMO21
XM_001127385LOC7307761
XM_001128769LOC7288251
NM_020438DOLPP11
NM_002737PRKCA1
NM_003099SNX11
NM_152826SNX11
NM_148955SNX11
XM_001133778LOC7317101
XM_001129849LOC7282491
NM_145862CHEK21
NM_001005735CHEK21
NM_007194CHEK21
NM_021079NMT11
NM_022779DDX311
NM_018667SMPD31
NM_175575WFIKKN21
NM_006544EXOC51
NM_014872ZBTB51
NM_001860SLC31A21
NM_032501ACSS11
NM_033224PURB1
NM_006293TYRO31
NM_002210ITGAV1
NM_001001875TPD52L31
NM_033516TPD52L31
NM_173851SLC30A81
NM_203453PPAPDC21
NM_170665ATP2A21
NM_018006TRMU1
NM_022744C16orf581
NM_139056ADAMTS161
NM_015260SIN3B1
NM_022437ABCG81
XM_499356LOC4426091
XM_935540LOC4426091
NM_175064WBSCR191
XM_499348MGC573591
XM_001127525LOC7303071
XM_496899LOC4412581
XM_929470LOC6439091
XM_001127430LOC7303041
NM_0010994351
NM_001033518WIPI21
NM_001033519WIPI21
NM_015610WIPI21
NM_001033520WIPI21
NM_016003WIPI21
NM_021004DHRS41
NM_198083DHRS4L21
NM_203394E2F71
NM_014844KIAA03291
NM_018085IPO91
NM_134433RFX21
NM_000635RFX21
NM_020354ENTPD71
NM_030640DUSP161
NM_001031672LOC6064951
NM_015266SLC9A81
NM_021625TRPV41
NM_147204TRPV41
NM_0010994041
NM_198056SCN5A1
NM_0010994051
NM_000335SCN5A1
NM_198709ARSB1
NM_001720BMP8B1
NM_052898XKR41
XM_942692MGC51391
NM_001080533MGC51391
XM_940667SDC31
NM_016145C19orf561
NM_017849TMEM1271
NM_021926ALX41
NM_052905FMNL21
NM_133266SHANK21
NM_014143CD2741
NM_018188ATAD3A1
NM_025230WDR231
NM_181357WDR231
NM_194071CREB3L21
NM_024653PRKRIP11
NM_005683GPR551
NM_014030GIT11
NM_0010854541
NM_003885CDK5R11
NM_001004304ZNF7401
NM_152678FAM116A1
XM_001132771FAM116A1
NM_032211LOXL41
NM_030650KIAA17151
NM_0011050791
NM_0010982701
NM_002409MGAT31
NM_006454MXD41
XM_001129158LIMS11
XM_936833LOC6441961
XM_927389LOC6441961
NM_005759ABI21
NM_007148ZNF1791
NM_024607PPP1R3B1
NM_016436PHF201
NM_024080TRPM81
XM_001126750ABI21
NM_033449FCHSD11
NM_021128POLR2L1
NM_001005502CPM1
NM_198320CPM1
NM_001874CPM1
XM_943388LOC6437231
XM_931767LOC6437231
NM_001986ETV41
NM_001079675ETV41
NM_133433NIPBL1
NM_2073061
NM_018279TMEM191
XM_001134308LOC7322751
NM_001030288SPN1
NM_003123SPN1
NM_014431KIAA12741
NM_022464SIL11
NM_001037633SIL11
XM_937029LOC6479711
XM_001132825LOC7301831
NM_058244WNT8A1
NM_003893LDB11
NM_014638PLCH21
NM_014665LRRC141
NM_024959SLC24A61
NM_134444NLRP41
NM_153442GPR261
NM_004491GRLF11
NM_014746RNF1441
NM_004884PUNC1
NM_024807TREML21
NM_012308FBXL111
NM_003974DOK21
NM_001083924C1orf1161
NM_023938C1orf1161
NM_001543NDST11
XM_936119LOC6420441
XM_936165LOC6420751
XM_933843LOC6467201
XM_945002LOC6518951
NM_018265C1orf1061
NM_022468MMP251
NM_022777RABL51
NM_001365DLG41
NM_001026213CYP11B11
NM_000497CYP11B11
NM_000498CYP11B21
NM_031936GPR611
NM_080744SRCRB4D1
NM_004991MDS11
NM_016173HEMK11
NM_152785GCET21
NM_001008756GCET21
NM_002214ITGB81
NM_020205OTUD7B1
NM_025061LRRC8E1
NM_001260CDK81
NM_001037954DIXDC11
NM_033425DIXDC11
NM_024754PTCD21
NM_152914MGC338941
NM_015277NEDD4L1
NM_006861RAB351
NM_017994C7orf421
NM_001547IFIT21
NM_005883APC21
NM_022770GINS31
NM_022047DEF61
NM_001417EIF4B1
NM_015077SARM11
NM_015097CLASP21
NM_025233COASY1
NM_001042530COASY1
NM_001042531COASY1
NM_001042529COASY1
NM_001042532COASY1
NM_032451SPIRE21
NM_000525KCNJ111
NM_018313PBRM11
NM_181042PBRM11
NM_018165PBRM11
NM_020940KIAA16001
NM_032795RPUSD41
NM_014424HSPB71
NM_003014SFRP41
NM_013371IL191
NM_153758IL191
NM_014574STRN31
NM_001083893STRN31
NM_000362TIMP31
NM_138797ANKRD541
NM_032881LSM101
NM_023112OTUB21
NM_000686AGTR21
XM_001130790KIAA18811
NM_001080400KIAA18811
NM_019887DIABLO1
NM_138929DIABLO1
NM_138930DIABLO1
NM_001174ARHGAP61
NM_014694ADAMTSL21
NM_201526ISLR1
NM_005545ISLR1
XM_933796SLC45A41
XM_944850SLC45A41
NM_001080431SLC45A41
NM_001039591USP9X1
NM_001039590USP9X1
NM_198269HIPK11
NM_181358HIPK11
NM_198268HIPK11
NM_002382MAX1
NM_145113MAX1
NM_145112MAX1
NM_030916PVRL41
NM_173344ST3GAL11
NM_003033ST3GAL11
XM_001132703FLJ410471
XM_001133280FLJ410471
NM_032119GPR981
NM_004992MECP21
NM_001858COL19A11
NM_178128FADS61
NM_152529GPR1551
NM_001033045GPR1551
NM_002068GNA151
XM_498986LOC4410521
XM_944238LOC4410521
NM_004573PLCB21
NM_002242KCNJ131
NM_014810CEP3501
NM_020673RAB22A1
NM_020653ZNF2871
NM_002997SDC11
NM_001006946SDC11
NM_153456HS6ST31
NM_182913SYNE21
NM_015180SYNE21
NM_182910SYNE21
NM_182914SYNE21
NM_006952UPK1B1
NM_022719DGCR141
NM_001008693CST91
NM_022473ZFP1061
NM_025079ZC3H12A1
NM_022897RANBP171
NM_194284CLDN231
NM_001039199C20orf1211
NM_024331C20orf1211
NM_001017420ESCO21
NM_001008701LPHN11
NM_014921LPHN11
NM_152267RNF1851
NM_005994TBX21
NM_177543PPAP2C1
NM_003712PPAP2C1
NM_177526PPAP2C1
NM_014729TOX1
NM_022039FBXW41
NM_001006656ZNF4731
NM_015428ZNF4731
NM_017811UBE2R21
NM_017923MARCH11
NM_004654USP9Y1
NM_005242F2RL11
NM_032681SPRYD51
XM_374917LOC3999371
XM_930197LOC3999371
XM_374920LOC3999401
XM_934453LOC3999401
NM_004444EPHB41
NM_018662DISC11
NM_001012957DISC11
NM_005240ETV31
NM_021960MCL11
NM_182763MCL11
NM_005927MFAP31
NM_012214MGAT4A1
XM_928464LOC1465171
NM_013396USP251
NM_016091EIF3S6IP1
NM_020143PNO11
NM_022829SLC13A31
NM_001011554SLC13A31
NM_015270ADCY61
NM_020983ADCY61
NM_018012KIF26B1
NM_012157FBXL21
NM_006470TRIM161
NM_207361FREM21
NM_006397RNASEH2A1
NM_003247THBS21
NM_000388CASR1
NM_002613PDPK11
NM_031268PDPK11
NM_133482RAD501
NM_005732RAD501
NM_144578C14orf321
NM_0207331
NM_0011045481
NM_001698AUH1
NM_033646CDH71
NM_004361CDH71
NM_017848FAM120C1
NM_021783EDA2R1
NM_024516C16orf531
NM_032826SLC35B41
NM_002103GYS11
NM_0011001641
NM_0011001661
NM_014721PHACTR21
NM_0011001651
XM_939111LOC6500201
NM_152649MLKL1
XM_929433LOC6440061
NM_002938RNF41
NM_001005354PRR131
NM_018457PRR131
NM_145735ARHGEF71
NM_001001702FLJ333601
NM_016060MED311
NM_181654CPLX41
NM_001079809TMEM183B1
NM_138391TMEM183A1
NM_017762MTMR101
NM_030621DICER11
NM_177438DICER11
NM_001017916CYB5611
NM_001915CYB5611
NM_001017917CYB5611
NM_018132CENPQ1
NM_014757MAML11
XM_001126853MAML11
NM_014310RASD21
NM_001307CLDN71
NM_016075VPS361
NM_207582HERV-FRD1
NM_052885SLC2A131
NM_001040285PAPD51
NM_001040284PAPD51
NM_016348C5orf41
NM_032385C5orf41
XM_943571LOC6469161
NM_194452RNF1211
NM_194453RNF1211
NM_018320RNF1211
NM_003855IL18R11
NM_001004308ZCCHC161
NM_134325SLC26A91
NM_052934SLC26A91
XM_942458LOC2833981
XM_208658LOC2833981
NM_018482DDEF11
NM_007011ABHD21
NM_152924ABHD21
NM_001455FOXO3A1
NM_201559FOXO3A1
NM_005769CHST41
NM_018003UACA1
NM_001008224UACA1
NM_004963GUCY2C1
NM_021818SAV11
NM_007231SLC6A141
NM_004774PPARBP1
NM_003848SUCLG21
NM_006912RIT11
NM_0121941
NM_178571MGC510251
NM_001037330TRIM16L1
XM_001131982LOC7311091
NM_006378SEMA4D1
XM_001131803LOC7320781
NM_017902HIF1AN1
NM_181727SPATA121
NM_0011009121
NM_001669ARSD1
NM_022170EIF4H1
NM_031992EIF4H1
NM_030815PDRG11
NM_020845PITPNM21
NM_001004349FLJ454221
NM_002408MGAT21
NM_014603CDR2L1
NM_199461NANOS11
NM_016639TNFRSF12A1
NM_000727CACNG11
NM_002479MYOG1
NM_022895C12orf431
NM_006549CAMKK21
NM_153499CAMKK21
NM_153500CAMKK21
NM_172216CAMKK21
NM_172226CAMKK21
NM_004145MYO9B1
NM_001361DHODH1
NM_017515SLC35F21
NM_015375RIPK51
NM_199462RIPK51
NM_001632ALPP1
NM_031313ALPPL21
NM_138736GNAO11
NM_001014431AKT11
NM_001014432AKT11
NM_005163AKT11
NM_207419C1QTNF81
XM_001134414C1orf1331
XM_001134416C1orf1331
NM_0010987981
NM_0010987971
NM_0010987961
NM_032883TOX21
NM_006578GNB51
NM_016194GNB51
NM_021574BCR1
NM_004327BCR1
NM_001042413GLIS31
NM_152629GLIS31
NM_002868RAB5B1
NM_003898SYNJ21
NM_025187C16orf701
NM_019070DDX491
NM_175747OLIG31
NM_181784SPRED21
NM_138401FAM125A1
NM_005436CCDC61
NM_145321OSBPL31
NM_145320OSBPL31
NM_145322OSBPL31
NM_015550OSBPL31
NM_178858SFXN21
NM_152553IBRDC11
NM_001343DAB21
NM_020640DCUN1D11
NM_003435ZNF1341
NM_152389CCDC1081
XM_001130170LOC7292751
XM_001127723LOC7308781
XM_374276LOC3896761
XM_942972LOC3896761
XM_945019LOC6434411
XM_933124LOC6434411
NM_020433JPH21
NM_032960MAPKAPK21
NM_004759MAPKAPK21
NM_001080745DGKG1
NM_001346DGKG1
NM_001080744DGKG1
NM_001082959SCARB11
NM_005505SCARB11
NM_015025MYT1L1
NM_173080SPRR41
NM_002125HLA-DRB51
XM_001127362KIAA05741
NM_015272KIAA10051
NM_005629SLC6A81
NM_0011024671
NM_198998AQP12A1
NM_000292PHKA21
NM_001033910TRAF51
NM_145759TRAF51
NM_004619TRAF51
NM_001793CDH31
NM_207112HAGHL1
NM_032304HAGHL1
NM_175571GIMAP81
NM_025179PLXNA21
NM_013252CLEC5A1
NM_015455CNOT61
NM_198458ZNF4971
NM_015361R3HDM11
NM_016308CMPK1
NM_000724CACNB21
NM_201596CACNB21
NM_201571CACNB21
NM_201593CACNB21
NM_201590CACNB21
NM_201572CACNB21
NM_201597CACNB21
NM_201570CACNB21
NM_013238DNAJC151
NM_006334OLFM11
NM_152261C12orf231
XM_001134363FOXK21
XM_001134364FOXK21
NM_004514FOXK21
XM_001129929LOC7283391
XM_001133196LOC7315071
NM_014732KIAA05131
NM_024612DHX401
NM_001037164ARL4A1
NM_005738ARL4A1
NM_212460ARL4A1
NM_001042599ERBB41
NM_005235ERBB41
NM_145691ATPAF21
NM_006038SPATA21
NM_178457C20orf1741
NM_001007540LOC3891181
NM_001040455SIDT21
NM_002714PPP1R101
NM_016231NLK1
NM_013388PREB1
NM_006282STK41
NM_013382POMT21
NM_0011111131
NM_005339HIP21
NM_0011111121
NM_006141DYNC1LI21
NM_138620DDX311
NM_020888KIAA15221
NM_001030047KLK31
NM_001030049KLK31
NM_001648KLK31
NM_001030048KLK31
NM_130446KLHL61
NM_017586C9orf71
NM_007017SOX301
NM_022482GZF11
NM_138450ARL111
NM_001033723ZNF7041
XM_943193LOC4000271
XM_931434LOC4000271
NM_015042ZNF6091
NM_001080398KIAA03681
XM_001131778KIAA03681
NM_0011126631
NM_006629ZNF2711
NM_194313C9orf481
NM_001080439HSF51
XM_939614HSF51
NM_000960PTGIR1
NM_017482ADD21
NM_017484ADD21
NM_001017418SPRR2B1
NM_020144PAPOLB1
NM_080657RSAD21
NM_182764ELMO21
NM_133171ELMO21
XM_001128475LOC2851911
NM_182498ZNF4281
NM_144570HN1L1
NM_000418IL4R1
NM_001013842C8orf581
NM_000254MTR1
NM_018319TDP11
NM_001008744TDP11
NM_145261DNAJC191
NM_002404MFAP41
NM_032256TMEM1171
XM_939547ZNF6971
NM_001080470ZNF6971
XM_001131702LOC1527421
XM_001128848LOC1527421
NM_170692RASAL21
NM_004841RASAL21
NM_001005337PKP11
NM_000299PKP11
NM_032324C1orf571
NM_015678NBEA1
NM_0133181
NM_0010982101
NM_001904CTNNB11
NM_0010982091
NM_014761KIAA01741
NM_001624AIM11
NM_013235RNASEN1
NM_0011004121
NM_001003800BICD21
NM_015250BICD21
NM_006862TDRKH1
NM_000130F51
NM_001033925TIAL11
NM_003252TIAL11
NM_001942DSG11
NM_024671ZNF7681
NM_175861TMTC11
NM_001039697SNAPC31
NM_138571HINT31
NM_181844BCL6B1
NM_001024680LOC5542511
XM_293918LOC3456431
XM_938591LOC3456431
NM_000332ATXN11
NM_139265EHD41
NM_005435ARHGEF51
NM_0209111
NM_001006600ERBB2IP1
NM_018695ERBB2IP1
NM_032924ZNF31
NM_033260FOXQ11
NM_017847C1orf271
NM_016929CLIC51
NM_003047SLC9A11
NM_015055SWAP701
NM_001013691LOC4018981
NM_014877HELZ1
NM_001079846CREBBP1
NM_004380CREBBP1
NM_016061YPEL51
NM_001106ACVR2B1
NM_030629CMIP1
NM_198390CMIP1
NM_001007246BRWD11
NM_001261CDK91
NM_024956TMEM621
NM_024828C9orf821
NM_014570ARFGAP31
NM_003433ZNF1321
NM_024095ASB81
NM_003452ZNF1891
NM_197977ZNF1891
NM_006013RPL101
NM_030776ZBP11
NM_032758PHF5A1
NM_001008529MXRA71
NM_198530MXRA71
NM_001042535CENTG31
NM_014802KIAA05281
NM_198829RAC11
NM_006908RAC11
NM_018890RAC11
NM_005082TRIM251
NM_172101CD8B1
NM_003590CUL31
NM_014233UBTF1
NM_001076683UBTF1
NM_001076684UBTF1
NM_138426GLCCI11
NM_000690ALDH21
NM_001776ENTPD11
NM_0010981751
NM_007007CPSF61
NM_017545HAO11
NM_0010994131
NM_0010994121
NM_006766MYST31
NM_005324H3F3B1
NM_019020TBC1D161
NM_014906PPM1E1
NM_148899FOXP21
NM_014491FOXP21
NM_148898FOXP21
NM_001038704C17orf471
NM_001080975REPS21
NM_004726REPS21
NM_002918RFX11
NM_002874RAD23B1
NM_145687MAP4K41
NM_145686MAP4K41
NM_004834MAP4K41
NM_017799C14orf1011
NM_002881RALB1
NM_020211RGMA1
NM_018287ARHGAP121
NM_004956ETV11
NM_001010903DKFZp779B15401
NM_138428C1orf2121
NM_0011113191
NM_005986SOX11
NM_017763RNF431
NM_001304CPD1
NM_003034ST8SIA11
NM_012223MYO1B1
NM_015554GLCE1
NM_014634PPM1F1

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317