Predicted Off-targets for siRNA "aaacuacuguuguuagacga" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

4 hits were found for AACUACUGUUGUUAGACGA (3 guide strand hits and 1 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_016131 RAB10 3046 3064 AcCUACUGUUGUUAGAuuA62 3 14 ac false   <90%   3517
NM_018429 BDP1 10213 10231 AACUACUGcUGUUAGAgcA13 3 8 c false   <90%   11097
NM_012198 GCA 589 607 AACUACUaUUGUUAaACGu8 3 7 c false   <90%   1642


Hits to Sense strand


AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_013261 PPARGC1A 4116 4134 UucUCUAuCAACAGUAGUU6 3 11 bc false   <90%   6318


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1692
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_031435THAP24
NM_024492LPAL24
NM_181489ZNF4453
NM_005160ADRBK23
XM_001128799MAP3K23
NM_006609MAP3K23
NM_005188CBL3
NM_0011016763
NM_014864FAM20B3
NM_012382TTC333
NM_006947SRP723
NM_006203PDE4D3
NM_0011046313
NM_003489NRIP13
NM_145727LPAL23
NM_021189CADM32
NM_001858COL19A12
NM_017650PPP1R9A2
NM_006154NEDD42
NM_198400NEDD42
NM_032943SYTL22
NM_206929SYTL22
NM_206930SYTL22
NM_206927SYTL22
NM_032379SYTL22
NM_206928SYTL22
NM_015285WDR72
NM_052834WDR72
XM_001132480SLCO3A12
NM_207406CCDC42
NM_007038ADAMTS52
NM_001031700C4orf182
NM_016613C4orf182
NM_004370COL12A12
NM_080645COL12A12
NM_018490LGR42
NM_138340ABHD32
NM_015387PREI32
NM_199482PREI32
NM_0011008192
NM_001664RHOA2
NM_014253ODZ12
NM_021982SEC24A2
NM_020375C12orf52
NM_138468ICA1L2
NM_005840SPRY32
NM_001776ENTPD12
NM_0010981752
NM_018241TMEM342
NM_012173FBXO252
NM_183420FBXO252
NM_183421FBXO252
XM_930805LOC6424262
XM_932285LOC6446522
XM_001128660LOC7288662
NM_032121DKFZp564K1422
XM_932289LOC6446602
XM_943717LOC6446602
NM_031845MAP22
NM_031847MAP22
NM_001039538MAP22
NM_002374MAP22
NM_007077AP4S12
NM_007137ZNF812
NM_212558LOC4014982
NM_005935AFF12
NM_020154C15orf242
NM_001037293PALM22
NM_053016PALM22
NM_182898CREB52
NM_004904CREB52
NM_001011666CREB52
NM_182899CREB52
NM_001077204CSPP12
NM_024790CSPP12
NM_033394TANC12
NM_144571CNOT6L2
NM_178498SLC5A122
NM_013381TRHDE2
NM_032458PHF62
NM_001015877PHF62
NM_000788DCK2
NM_198843SFTPB2
NM_172071RC3H12
NM_0011026512
NM_177538CYP20A12
NM_015225KIAA03672
NM_006047RBM122
NM_152838RBM122
NM_0011001642
NM_0011001662
NM_014721PHACTR22
NM_0011001652
NM_017759FLJ203092
NM_016422RNF1412
NM_021912GABRB32
NM_000814GABRB32
NM_145259ACVR1C2
NM_0011110312
NM_0011110332
NM_0011110322
NM_152263TPM32
NM_173629C18orf262
NM_152586USP542
NM_018698NXT22
NM_001010891MTX32
NM_006888CALM12
NM_173468MOBKL1A2
NM_001039396MPEG12
NM_016513ICK2
NM_014920ICK2
XM_001134215PDPR2
NM_001167BIRC42
NM_001042601TTC142
NM_133265AMOT2
NM_2073062
NM_012431SEMA3E2
NM_005433YES12
NM_004171SLC1A22
NM_001033571AMZ22
NM_001033574AMZ22
NM_001033572AMZ22
NM_001033569AMZ22
NM_001033570AMZ22
NM_016627AMZ22
NM_181744OPN52
NM_001030051OPN52
NM_006352ZNF2382
NM_205768ZNF2382
NM_139279MCFD22
NM_017423GALNT72
NM_007249KLF122
NM_016441CRIM12
NM_016946F11R2
NM_006614CHL12
NM_003787NOL42
NM_001040107HVCN12
NM_032369HVCN12
NM_206853QKI2
NM_206854QKI2
NM_206855QKI2
NM_152837SNX162
NM_152836SNX162
NM_022133SNX162
NM_005400PRKCE2
NM_015097CLASP22
NM_003406YWHAZ2
NM_145690YWHAZ2
NM_199421SOCS42
NM_080867SOCS42
NM_014912CPEB32
NM_145037FAM55C2
NM_016052RRP152
NM_004337OSGIN22
NM_023016ANKRD572
NM_052832SLC26A72
NM_003212TDGF12
NM_016218POLK2
NM_001039199C20orf1212
NM_024331C20orf1212
NM_194329RNF382
NM_194328RNF382
NM_194330RNF382
NM_022781RNF382
NM_194332RNF382
NM_001006600ERBB2IP2
NM_018695ERBB2IP2
NM_007331WHSC12
NM_018279TMEM191
NM_016275SELT1
NM_033251RPL131
NM_000977RPL131
NM_018423STYK11
NM_0247761
NM_022059CXCL161
NM_032312YIPF41
NM_004788UBE4A1
NM_013269CLEC2D1
NM_001004419CLEC2D1
NM_018261EXOC11
NM_178237EXOC11
NM_001024924EXOC11
NM_024575TNFAIP8L21
XM_001130518LOC7284851
XM_001133894LOC7319641
NM_017443POLE31
NM_024596MCPH11
NM_006364SEC23A1
NM_173526C14orf541
NM_000518HBB1
NM_182978GNAL1
NM_014729TOX1
NM_005538INHBC1
NM_145307PLEKHK11
NM_033439IL331
NM_000603NOS31
NM_006496GNAI31
NM_006402HBXIP1
NM_153697ANKRD441
NM_057749CCNE21
NM_016045SLMO21
NM_001003652SMAD21
NM_005901SMAD21
NM_003134SRP141
NM_007006NUDT211
NM_144988ALG141
NM_002556OSBP1
NM_033161SURF41
NM_005665EVI51
NM_025195TRIB11
NM_003941WASL1
NM_170774RASSF21
NM_014737RASSF21
NM_004867ITM2A1
NM_018119POLR3E1
NM_020809ARHGAP201
NM_003429ZNF851
NM_020993BCL7A1
NM_001024808BCL7A1
NM_177424STX121
NM_144722FLJ235771
NM_139276STAT31
NM_003150STAT31
NM_213662STAT31
NM_003725HSD17B61
NM_004929CALB11
NM_014048MKL21
NM_017952PTCD31
NM_021163RBAK1
NM_152224PPEF11
NM_152226PPEF11
NM_006240PPEF11
NM_000602SERPINE11
NM_018841GNG121
NM_139281WDR361
XM_940318FLJ404111
NM_001080504FLJ404111
NM_001039111TRIM711
NM_002645PIK3C2A1
NM_016525UBAP11
NM_014686KIAA03551
NM_173497HECTD21
NM_0204591
NM_001949E2F31
XM_001134020LOC7318651
NM_0011098781
NM_016954TBX221
NM_0011098791
NM_080927DCBLD21
NM_018046AGGF11
NM_000705ATP4B1
NM_002747MAPK41
NM_001002814RAB11FIP11
NM_198480ZNF6151
NM_147189FAM110B1
NM_001040202PAQR31
NM_015079TBC1D2B1
NM_003482MLL21
NM_006379SEMA3C1
NM_006955ZNF33B1
XM_001133106LOC4007561
XM_001130528LOC4007561
NM_015192PLCB11
NM_182734PLCB11
NM_020369FSCN31
NM_014243ADAMTS31
NM_173529C18orf541
NM_019863F81
NM_000132F81
NM_002357MXD11
NM_006915RP21
XM_944029LOC6479791
NM_017832C9orf61
NM_025221KCNIP41
NM_001035003KCNIP41
NM_001035004KCNIP41
NM_147183KCNIP41
NM_147182KCNIP41
NM_147181KCNIP41
NM_178844NLRC31
NM_016026RDH111
NM_182833GDPD41
NM_004004GJB21
NM_020679MIF4GD1
NM_014942ANKRD61
NM_012446SSBP21
NM_005595NFIA1
NM_020340KIAA12441
NM_016302CRBN1
NM_024699ZFAND11
NM_001829CLCN31
NM_173872CLCN31
NM_006718PLAGL11
NM_002656PLAGL11
NM_001080951PLAGL11
NM_001080954PLAGL11
NM_001080953PLAGL11
NM_001080956PLAGL11
NM_001080955PLAGL11
NM_001080952PLAGL11
NM_177925H2AFJ1
NM_178342C3orf351
NM_152630FAM46D1
NM_001146ANGPT11
NM_183238ZNF6051
NM_012474UCK21
NM_0011055731
XM_001134327LOC7323241
XM_001134208LOC7299751
NM_017738C9orf391
NM_006345SLC30A91
NM_032445MEGF111
NM_206809MOG1
NM_001008229MOG1
NM_001008228MOG1
NM_206811MOG1
NM_002433MOG1
NM_206812MOG1
NM_206810MOG1
NM_018080VPS13C1
NM_001018088VPS13C1
NM_001039618CREBZF1
NM_022568ALDH8A11
NM_170771ALDH8A11
NM_003948CDKL21
NM_004820CYP7B11
NM_007084SOX211
NM_001001411ZNF6761
NM_015967PTPN221
NM_001460FMO21
NM_0221591
NM_015346ZFYVE261
NM_001077243GRIA41
NM_000829GRIA41
NM_005158ABL21
NM_007314ABL21
NM_0011001081
NM_0011004211
NM_0011004201
NM_017447C21orf911
NM_031912SYT151
NM_019022TXNDC101
NM_006577B3GNT21
NM_020768KCTD161
NM_018264TYW11
XM_001125756LOC7277881
XM_001125734LOC7277811
NM_0011052141
NM_004674ASH2L1
NM_006505PVR1
NM_0334031
NM_001025252TPD521
NM_001025253TPD521
NM_005079TPD521
NM_032578MYPN1
NM_001334CTSO1
NM_213609FAM19A11
XM_928464LOC1465171
NM_014930ZNF5101
XM_001129792LOC7291481
NM_138459NUS11
NM_022778CCDC211
NM_153021PLB11
NM_003144SSR11
NM_020718USP311
NM_144973MGC240391
NM_153346CXorf201
NM_178815ARL5B1
NM_002718PPP2R3A1
NM_181897PPP2R3A1
NM_002063GLRA21
NM_133458ZFP901
NM_144977DENND1B1
NM_018979WNK11
NM_001005609EDA1
NM_001399EDA1
NM_005737ARL4C1
NM_020633VN1R11
NM_006699MAN1A21
NM_007030TPPP1
XM_001133521MGC513381
XM_001132564LOC7288821
NM_000902MME1
NM_007289MME1
NM_007288MME1
NM_007287MME1
NM_019067GNL3L1
NM_032622LNX11
NM_013256ZNF1801
NM_017810ZNF4341
NM_020879KIAA15051
NM_015163TRIM91
NM_001012980SATL11
NM_138571HINT31
NM_138333FAM122A1
NM_021191NEUROD41
NM_001012756ZNF2601
NM_004938DAPK11
NM_019080NDFIP21
NM_178125TRIM501
NM_020377CYSLTR21
NM_001039580MAP91
NM_005139ANXA31
NM_002562P2RX71
NM_007322RANBP31
NM_003624RANBP31
NM_018323PI4K2B1
NM_018976SLC38A21
NM_001077349ZNF6821
NM_033196ZNF6821
NM_004504HRB1
NM_020466LYRM21
NM_014058TMPRSS11E1
NM_0010996621
NM_003372VBP11
NM_001079809TMEM183B1
NM_138391TMEM183A1
NM_182925FLT41
NM_004728DDX211
NM_024617ZCCHC61
NM_021045ZNF2481
NM_175852TXLNA1
NM_001537HSBP11
NM_025133FBXO111
NM_052917GALNT131
NM_001012959DISC11
NM_004932CDH61
NM_013362ZNF2251
NM_003747TNKS1
NM_004572PKP21
NM_001005242PKP21
NM_144979MGC270161
NM_015251ASCIZ1
NM_004434EML11
NM_001008707EML11
NM_001004317LIN28B1
NM_139201GIT21
NM_000314PTEN1
NM_000345SNCA1
NM_001042682RERE1
NM_012102RERE1
NM_001042681RERE1
NM_004248PRLHR1
NM_016252BIRC61
NM_001002258ATP5G31
NM_001689ATP5G31
NM_015469NIPSNAP3A1
NM_006022TSC22D11
NM_183422TSC22D11
NM_002586PBX21
NM_001013620ALG10B1
NM_032973PCDH11Y1
NM_032968PCDH11X1
NM_032969PCDH11X1
NM_018191RCBTB11
NM_152344LSM121
NM_145273CD300LG1
NM_004263SEMA4F1
NM_001002247ANAPC111
NM_001002248ANAPC111
NM_016476ANAPC111
NM_001002249ANAPC111
NM_001002245ANAPC111
NM_001002246ANAPC111
NM_001002244ANAPC111
XM_001133283LOC7289191
XM_001133292LOC7289191
XM_001133288LOC7289191
XM_001133297LOC7289191
XM_943028LOC6477951
NM_032449CC2D1B1
NM_003714STC21
NM_001037172ACPL21
NM_152282ACPL21
NM_032576CYorf15B1
NM_012250RRAS21
NM_0011026691
NM_001010853ACY1L21
NM_016563RASL121
NM_175066DDX511
NM_001004351MGC573591
NM_152437ZNF6641
NM_001025266LOC2853821
NM_207327LOC1503831
NM_015159KIAA02801
NM_202003FOXM11
NM_202002FOXM11
NM_021953FOXM11
NM_147156SGMS11
NM_006775QKI1
NM_001042493C6orf1621
NM_020425C6orf1621
NM_181308WDR201
NM_144574WDR201
NM_181302WDR201
NM_003408ZFP371
NM_014803ZNF5181
NM_007167ZMYM61
NM_024080TRPM81
NM_006832PLEKHC11
NM_025164KIAA09991
NM_015332NUDCD31
NM_020951ZNF5291
XM_001125970LOC7304651
NM_153022C12orf591
NM_001008572TTLL11
NM_012263TTLL11
NM_173540FUT111
NM_000885ITGA41
NM_014897ZNF6521
NM_014341MTCH11
NM_006037HDAC41
NM_015015JMJD2B1
XM_001126066LOC7304971
XM_375443LOC2841001
NM_133367PAQR81
NM_198493ANKRD451
NM_018096NLE11
NM_001014445NLE11
NM_025059C6orf971
NM_017644KLHL241
NM_000368TSC11
NM_000697ALOX121
NM_0333901
NM_173602DIP2B1
XM_927226LOC6429211
NM_004901ENTPD41
NM_023923PHACTR41
NM_001048183PHACTR41
NM_018440PAG11
NM_015453THUMPD31
NM_001039768LCAP1
NM_000579CCR51
NM_0011001681
NM_0011055361
NM_022748TNS31
NM_175768GRIK21
NM_021956GRIK21
NM_020318PAPPA21
NM_198889ANKRD171
NM_032217ANKRD171
NM_197975BTNL31
NM_014876JOSD11
NM_014913ZNF5081
NM_181523PIK3R11
NM_181504PIK3R11
NM_181524PIK3R11
XM_939315LOC6441501
XM_935705LOC6441501
NM_001080529WIPF31
XM_001129292MBOAT21
NM_0011006211
NM_017941C17orf801
NM_014112TRPS11
NM_173519MGC346461
NM_175056ZPLD11
NM_201546CDCP21
NM_030820COL21A11
NM_001031710KLHL71
NM_207103UNQ57831
NM_001039152RGS211
NM_019036HMGCLL11
NM_001042406HMGCLL11
NM_020214PARP61
NM_001013627LOC3405271
NM_014141CNTNAP21
NM_013348KCNJ141
NM_170720KCNJ141
NM_002277KRT311
NM_024654NOL91
XM_938104LOC6450181
XM_930178LOC6450181
NM_033554HLA-DPA11
NM_030883OR2H11
NM_025250TTYH31
NM_001005502CPM1
NM_198320CPM1
NM_001874CPM1
NM_000362TIMP31
NM_173463DKFZp761B1071
NM_015855WIT11
NM_021818SAV11
NM_006690MMP241
NM_015879ST8SIA31
NM_019089HES21
NM_021984GABRE1
NM_021987GABRE1
NM_004961GABRE1
NM_021990GABRE1
NM_013231FLRT21
NM_001706BCL61
NM_138931BCL61
NM_018649H2AFY21
NM_007048BTN3A11
NM_014755SERTAD21
NM_198484ZNF6211
NM_0010984141
NM_017754C6orf1071
XM_001126375LOC7279221
XM_001126361LOC7279221
XM_001126406LOC7279221
XM_001126391LOC7279221
XM_001126417LOC7279221
NM_006625FUSIP11
NM_006449CDC42EP31
NM_020810TRMT51
NM_016571GLULD11
NM_015633FGFR1OP21
NM_198849LOC2835141
NM_000441SLC26A41
NM_177965C8orf371
NM_005768MBOAT51
NM_000320QDPR1
NM_182907PRDM11
NM_001198PRDM11
XM_001130850LOC6458221
NM_198153TREML41
NM_016060MED311
NM_004727SLC24A11
NM_000139MS4A21
NM_025054VCPIP11
NM_024334TMEM431
NM_001004349FLJ454221
NM_000462UBE3A1
NM_130839UBE3A1
NM_130838UBE3A1
NM_004694SLC16A61
NM_032182KIAA01571
NM_133496SLC30A71
NM_007123USH2A1
XM_001124844LOC7304201
NM_032967PCDH11X1
NM_032972PCDH11Y1
NM_032971PCDH11Y1
NM_016216DBR11
NM_001159AOX11
NM_012333MYCBP1
NM_001766CD1D1
NM_020240CDC42SE21
NM_001038702CDC42SE21
NM_021201MS4A71
NM_206938MS4A71
NM_206940MS4A71
NM_206939MS4A71
NM_033448KRT711
NM_001026213CYP11B11
NM_000497CYP11B11
NM_024895PDZD71
NM_024779PIP5K2C1
NM_0010997811
NM_004121GGTLA11
NM_0010997821
NM_006328RBM141
NM_005292GPR181
NM_0010982001
NM_000791DHFR1
NM_003211TDG1
NM_001039547GK51
NM_003549HYAL31
NM_024946NIP301
NM_003644GAS71
NM_201432GAS71
NM_201433GAS71
NM_021637TMEM351
NM_004738VAPB1
NM_001002254DGAT2L41
NM_015423AASDHPPT1
NM_016598ZDHHC31
NM_032373PCGF51
NM_002832PTPN71
NM_080588PTPN71
NM_000346SOX91
NM_021023CFHR31
NM_002047GARS1
NM_201266NRP21
NM_003872NRP21
NM_201279NRP21
XM_001128001LOC7284011
XM_001127991LOC7284011
NM_001006623WDR331
NM_175607CNTN41
NM_175612CNTN41
NM_001462FPRL11
NM_001005738FPRL11
NM_014455ZNF3641
NM_175856CHSY-21
NM_012453TBL21
NM_032826SLC35B41
XM_001127568LOC7284991
XM_001127665LOC7285261
XM_001130826LOC7284521
XM_001130837LOC6433671
XM_932646LOC3400891
XM_001127715LOC7285401
XM_001127825LOC7285751
NM_002970SAT11
NM_015187KIAA07461
NM_001037954DIXDC11
NM_033425DIXDC11
NM_014646LPIN21
NM_080618CTCFL1
NM_020132AGPAT31
NM_001037553AGPAT31
NM_182607VSIG11
NM_1526341
NM_002009FGF71
XM_933333LOC6534491
NM_004734DCLK11
NM_003184TAF21
NM_001013439FXR11
NM_001013438FXR11
NM_005087FXR11
NM_007353GNA121
NM_012074DPF31
NM_032456PCDH71
NM_145321OSBPL31
NM_145320OSBPL31
NM_145322OSBPL31
NM_015550OSBPL31
NM_016351ADAM221
NM_021723ADAM221
NM_021722ADAM221
NM_014216ITPK11
NM_020342SLC39A101
NM_004923MTL51
NM_001080439HSF51
XM_939614HSF51
NM_033127LZTR21
NM_006216SERPINE21
NM_033296MRFAP11
NM_024312GNPTAB1
NM_003471KCNAB11
NM_172159KCNAB11
NM_172160KCNAB11
NM_001024380TM2D21
NM_078473TM2D21
NM_001024381TM2D21
NM_031940TM2D21
NM_001013655LOC3898341
XM_001125792LOC7278341
XM_926013LOC6423981
NM_001004313LOC3883351
NM_183065TMEM1071
NM_032354TMEM1071
NM_002998SDC21
NM_005063SCD1
NM_006620HBS1L1
NM_032810ATAD11
NM_006294UQCRB1
NM_000104CYP1B11
NM_001077637LOC1507861
NM_032144RAB6C1
NM_198896RAB6A1
NM_002869RAB6A1
NM_015047KIAA00901
NM_003659AGPS1
NM_004109FDX11
XM_001128243LOC7287051
NM_021109TMSB4X1
NM_183049TMSL31
NM_017438SETD41
XM_001133696LOC7316801
NM_002204ITGA31
NM_005501ITGA31
NM_014701KIAA02561
NM_007203PALM2-AKAP21
NM_147150PALM2-AKAP21
NM_001004065AKAP21
NM_004748CCPG11
NM_020739CCPG11
NM_001570IRAK21
NM_001033930UBA521
NM_003333UBA521
NM_017775TTC191
NM_013989DIO21
NM_001007023DIO21
NM_000793DIO21
NM_001080414KIAA15091
XM_496003KIAA15091
XM_941642KIAA15091
NM_003119SPG71
NM_004584RAD9A1
NM_001007097NTRK21
NM_173578C11orf721
NM_138292ATM1
NM_000051ATM1
NM_032105PPP1R12B1
NM_002481PPP1R12B1
NM_001037339PDE4B1
NM_002600PDE4B1
NM_001037340PDE4B1
NM_001037341PDE4B1
NM_003450ZNF1741
NM_032717MAG11
NM_003048SLC9A21
NM_182490ZNF2271
NM_152686DNAJC181
NM_014388C1orf1071
NM_052941GBP41
NM_022462HIF3A1
NM_152794HIF3A1
NM_152795HIF3A1
NM_139029CD1511
NM_004357CD1511
NM_001039490CD1511
NM_139030CD1511
XM_001131439FLJ340481
XM_001130034FLJ340481
XM_001131637FLJ340481
NM_013354CNOT71
NM_003201TFAM1
NM_016276SGK21
NM_170693SGK21
NM_207361FREM21
NM_004035ACOX11
NM_007292ACOX11
NM_005819STX61
NM_020935USP371
NM_000305PON21
NM_001018161PON21
XM_499010LOC4410971
XM_943902LOC4410971
NM_001042599ERBB41
NM_005235ERBB41
NM_015396ARMC81
NM_001765CD1C1
XM_938689KIAA16711
XM_371461KIAA16711
NM_000168GLI31
NM_003887DDEF21
XM_942780SYNPO21
NM_152444ZADH11
NM_012297G3BP21
NM_203504G3BP21
NM_203505G3BP21
NM_207429FLJ458031
NM_005437NCOA41
NM_032839DIRC21
NM_152347C17orf571
NM_033091TRIM41
NM_033017TRIM41
NM_002583PAWR1
NM_001042475C6orf2041
NM_003800RNGTT1
NM_001017980LOC2035471
NM_014522PCDH11X1
NM_053002MED12L1
NM_006269RP11
NM_152367C1orf1611
NM_006237POU4F11
NM_021815SLC5A71
NM_182553CNIH21
XM_001129488CNIH21
NM_005725TSPAN21
NM_017694FLJ201601
NM_0011025751
NM_001412EIF1AX1
NM_001560IL13RA11
XM_931447SETD51
XM_944298SETD51
XM_944295SETD51
XM_931444SETD51
NM_014661FAM53B1
NM_001007536AKR1CL11
NM_001017926ZHX11
NM_007222ZHX11
NM_021639GPBP1L11
NM_002666PLIN1
NM_016040TMED51
NM_201999ELF21
NM_006874ELF21
NM_020122KCMF11
XM_001133393KCMF11
NM_207295MBNL11
NM_207293MBNL11
NM_207297MBNL11
NM_207296MBNL11
NM_207294MBNL11
NM_021038MBNL11
NM_207292MBNL11
NM_013238DNAJC151
NM_145284FAM122B1
NM_014795ZEB21
NM_003075SMARCC21
NM_139067SMARCC21
NM_173698RP1-32F7.21
NM_006624ZMYND111
XM_001125875LOC7278181
NM_005792MPHOSPH61
XM_001134421C1orf1521
NM_021267LASS11
NM_003856IL1RL11
NM_0010992251
NM_144609CCDC431
NM_033637BTRC1
NM_003939BTRC1
NM_181609KRTAP19-31
NM_032385C5orf41
XM_933614LOC6464341
NM_030579CYB5B1
NM_002696POLR2G1
NM_0011127361
NM_015224C3orf631
NM_176823S100A7A1
NM_001496GFRA31
NM_031244SIRT51
NM_198174GRHL31
NM_021180GRHL31
NM_198173GRHL31
NM_002639SERPINB51
NM_0011024451
NM_005613RGS41
NM_005668ST8SIA41
NM_003567BCAR31
NM_001616ACVR2A1
NM_004290RNF141
NM_183400RNF141
NM_183398RNF141
NM_183401RNF141
NM_183399RNF141
NM_153042AOF11
NM_013449BAZ2A1
NM_022167XYLT21
NM_153354TMEM161B1
NM_000380XPA1
NM_001295CCR11
NM_002396ME21
NM_018429BDP11
NM_001563IMPG11
NM_015852ZNF1171
NM_001744CAMK41
XM_001132973LOC7291121
XM_001126439LOC7304891
NM_012390SMR3A1
NM_006685SMR3B1
NM_152291MUC71
NM_032980DTNA1
NM_001390DTNA1
NM_032975DTNA1
NM_173552C3orf581
NM_021216ZNF711
XM_001133559LOC6446341
NM_004393DAG11
XM_373553LOC3878951
XM_945559LOC3878951
NM_182749N6AMT11
NM_013240N6AMT11
NM_018431DOK51
XM_927029PPP1R3E1
XM_940069PPP1R3E1
NM_004845PCYT1B1
NM_019903ADD31
NM_016824ADD31
NM_001121ADD31
NM_001034841LOC1620731
NM_018360CXorf151
NM_014862ARNT21
NM_001010932HGF1
NM_000601HGF1
NM_014373GPR1601
NM_032042C5orf211
NM_020336KIAA12191
NM_024593EFCAB11
NM_024713C15orf291
NM_016599MYOZ21
NM_015176FBXO281
NM_199168CXCL121
NM_0011045461
NM_152431PIWIL41
NM_002664PLEK1
NM_213604ADAMTSL51
NM_0010987211
NM_0010987221
NM_004485GNG41
NM_018085IPO91
NM_012300FBXW111
NM_033644FBXW111
NM_033645FBXW111
NM_000349STAR1
NM_001007243STAR1
NM_020773TBC1D141
NM_001454FOXJ11
NM_139245PPM1L1
NM_014900COBLL11
NM_018029FLJ102131
NM_001018058TFEC1
NM_012252TFEC1
NM_145305SLC25A431
NM_201550LRRC101
NM_130799MEN11
NM_130801MEN11
NM_000244MEN11
NM_130803MEN11
NM_130800MEN11
NM_130804MEN11
NM_130802MEN11
NM_017923MARCH11
NM_000318PXMP31
NM_001079867PXMP31
NM_004992MECP21
XM_001125952LOC7278521
XM_001132609LOC7313661
NM_007106UBL31
NM_002486NCBP11
NM_015020PHLPPL1
NM_144633KCNH81
NM_205855UNQ19401
NM_017811UBE2R21
NM_001349DARS1
NM_001039591USP9X1
NM_001039590USP9X1
NM_004279PMPCB1
NM_001106ACVR2B1
NM_144717IL20RB1
NM_021809TGIF21
NM_153261TMEM1881
NM_153234LIX11
NM_004797ADIPOQ1
NM_052876BTBD14B1
NM_007153ZNF2081
NM_001029875RGS7BP1
NM_014917NTNG11
NM_0011132281
NM_0011132261
NM_000458TCF21
NM_175629DNMT3A1
NM_022552DNMT3A1
NM_153759DNMT3A1
NM_018433JMJD1A1
NM_006749SLC20A21
NM_145291ZNF5091
NM_001018056VLDLR1
NM_003383VLDLR1
NM_1735951
NM_016242EMCN1
NM_178013PRIMA11
NM_016374ARID4B1
NM_031371ARID4B1
NM_005302GPR371
NM_002637PHKA11
NM_006330LYPLA11
NM_005277GPM6A1
NM_201592GPM6A1
NM_201591GPM6A1
NM_144664FAM76B1
NM_014774KIAA04941
NM_020921NIN1
NM_002399MEIS21
NM_172316MEIS21
NM_170674MEIS21
NM_170675MEIS21
NM_170676MEIS21
NM_170677MEIS21
NM_172315MEIS21
NM_001148ANK21
NM_020977ANK21
NM_004958FRAP11
NM_007054KIF3A1
NM_024576OGFRL11
NM_145655GCNT21
NM_145649GCNT21
NM_001491GCNT21
XM_001132417LOC7312591
XM_001132664LOC7289871
NM_019074DLL41
NM_032682FOXP11
NM_001754RUNX11
NM_001001890RUNX11
NM_030637DDHD11
NM_006246PPP2R5E1
NM_173531ZNF1001
XM_938440LOC4006821
NM_014763MRPL191
NM_006014LAGE31
NM_002061GCLM1
XM_943975FLJ390801
XM_499117FLJ390801
NM_013358PADI11
NM_148170CTSC1
NM_005245FAT1
NM_0010984021
NM_0010984031
NM_020727ZNF2951
NM_022149MAGEF11
NM_004236COPS21
NM_203446SYNJ11
NM_003895SYNJ11
NM_015045WAPAL1
XM_940456FLJ221841
NM_002595PCTK21
NM_183394CADPS1
NM_003716CADPS1
NM_183393CADPS1
NM_001688ATP5F11
NM_001321CSRP21
NM_017415KLHL31
NM_014731ProSAPiP11
NM_005795CALCRL1
NM_000450SELE1
NM_001011516PDLIM51
NM_001011515PDLIM51
NM_018444PPM2C1
NM_176786IL9R1
NM_0010985031
NM_001040285PAPD51
NM_001040284PAPD51
NM_181846ZSCAN221
NM_001001549GRB101
NM_001001555GRB101
NM_001001550GRB101
NM_005311GRB101
NM_174911FAM84B1
NM_020940KIAA16001
NM_016952CDON1
NM_004703RABEP11
NM_001083585RABEP11
NM_000028AGL1
NM_000646AGL1
NM_000645AGL1
NM_000644AGL1
NM_000642AGL1
NM_000643AGL1
NM_000684ADRB11
NM_031302GLT8D21
NM_005260GDF91
NM_207111TRIAD31
NM_207116TRIAD31
NM_014431KIAA12741
NM_021111RECK1
XM_001127668LOC7281191
XM_001131429LOC7311181
NM_005252FOS1
NM_021830PEO11
NM_032439PHYHIPL1
XM_001134369LOC7301071
NM_004483GCSH1
XM_945736LOC6540851
NM_001009922RCHY11
NM_001008925RCHY11
NM_015436RCHY11
NM_133478SLC4A51
NM_020824ARHGAP211
NM_024523GCC11
NM_152556FLJ318181
NM_001018057DKK31
NM_013253DKK31
NM_015881DKK31
NM_006489NOVA11
NM_002515NOVA11
NM_005373MPL1
NM_002242KCNJ131
NM_024094DCC11
NM_198928PYHIN11
NM_152501PYHIN11
NM_016009SH3GLB11
NM_006106YAP11
NM_033121ANKRD13A1
NM_032160DSEL1
NM_206933USH2A1
NM_025000C2orf371
NM_030799YIPF51
NM_018479ECHDC11
NM_0010020301
NM_0011055441
NM_0011055451
NM_021954GJA31
NM_080671KCNE41
NM_001080497MEGF91
XM_936860MEGF91
NM_003617RGS51
NM_016284CNOT11
NM_002655PLAG11
NM_013396USP251
NM_019063EML41
NM_018602DNAJA41
NM_016316REV11
NM_001037872REV11
XM_001129972LOC7315341
XM_001132513LOC7301211
NM_017953C1orf1811
NM_031914SYT161
NM_019555ARHGEF31
NM_130446KLHL61
NM_014381MLH31
NM_001040108MLH31
NM_015497TMEM87A1
NM_152753SCUBE31
NM_052811TRIM131
NM_213590TRIM131
NM_001007278TRIM131
NM_005798TRIM131
NM_025191EDEM31
NM_018325C9orf721
NM_153810C10orf461
NM_0010895871
NM_175874C12orf601
NM_014659HISPPD2A1
NM_001024463HISPPD2A1
NM_002716PPP2R1B1
NM_145263SPATA181
NM_183050BCKDHB1
NM_002440MSH41
NM_138288C14orf1471
NM_145863ASB31
NM_016115ASB31
NM_017426NUP541
NM_006751SSFA21
NM_001012515FECH1
NM_000140FECH1
NM_144682SLFN131
NM_005504BCAT11
NM_173084TRIM591
NM_024639ZNF322A1
NM_199005ZNF322B1
NM_003588CUL4B1
NM_001079872CUL4B1
NM_001077440BCLAF11
NM_001077441BCLAF11
NM_014739BCLAF11
NM_032025EIF2A1
NM_032858MAEL1
NM_139319SLC17A81
NM_003473STAM1
NM_002781PSG51
NM_001029839C3orf231
NM_001029840C3orf231
XM_379623FLJ412001
XM_943473FLJ412001
NM_033114ZCRB11
NM_012253TKTL11
NM_001003698RREB11
NM_001003699RREB11
NM_002955RREB11
NM_058173SBEM1
NM_002264KPNA11
NM_182554C10orf531
NM_022659EBF21
NM_015198COBL1
NM_017719SNRK1
NM_0011005941
NM_001080415SR1401
XM_940802SR1401
NM_001083112GPD21
NM_000408GPD21
NM_024838THNSL11
NM_182551LYCAT1
NM_001002257LYCAT1
NM_005149TBX191
NM_006683FAM12A1
NM_006920SCN1A1
NM_198557RBM431
XM_049078KIAA12391
XM_940885KIAA12391
NM_021204ENOPH11
NM_001025079CD471
NM_001777CD471
NM_198793CD471
NM_024889C10orf811
NM_002024FMR11
NM_173851SLC30A81
NM_014943ZHX21
NM_153027FLJ316591
NM_001001556GALK21
NM_002044GALK21
NM_015092SMG11
NM_018189DPPA41
NM_214711LOC4011371
NM_130391PTPRD1
NM_130393PTPRD1
NM_130392PTPRD1
NM_002839PTPRD1
NM_001040712PTPRD1
NM_004884PUNC1
XM_946032LOC6448521
XM_934218LOC6448521
NM_000945PPP3R11
NM_012464TLL11
NM_001014797KCNMA11
NM_014982PCNX1
NM_004668MGAM1
NM_000909NPY1R1
NM_005259GDF81
NM_1488931
NM_198271LMOD31
NM_138362FAM104B1
NM_014518ZNF2291
NM_001077445PHF161
NM_014735PHF161
NM_017841C11orf791
NM_020806GPHN1
NM_001024218GPHN1
NM_178585WDFY31
NM_014991WDFY31
NM_203349SHC41
NM_133647SLC12A61
NM_001042495SLC12A61
NM_001042494SLC12A61
NM_001042497SLC12A61
NM_005135SLC12A61
NM_001042496SLC12A61
NM_015391ANAPC131
NM_007166PICALM1
NM_001008660PICALM1
NM_024808C13orf341
NM_021133RNASEL1
NM_031950FGFBP21
NM_002210ITGAV1
NM_024577SH3TC21
NM_001527HDAC21
NM_001018067SERBP11
NM_015640SERBP11
NM_001018069SERBP11
NM_001018068SERBP11
XM_001129713LOC7283341
XM_379380LOC4012221
XM_945580LOC4012201
XM_379378LOC4012201
NM_001914CYB5A1
NM_148923CYB5A1
NM_002581PAPPA1
NM_152588TMTC21
NM_0011016691
NM_003866INPP4B1
NM_004019DMD1
NM_182573LYPD51
NM_001031749LYPD51
NM_006856ATF71
NM_032521PARD6B1
NM_014517UBP11
NM_004737LARGE1
NM_133642LARGE1
NM_006868RAB311
NM_003758EIF3S11
NM_178842LASS31
NM_0146951
NM_024949WWC21
NM_023073FLJ132311
NM_002267KPNA31
NM_001083617RB1CC11
NM_014781RB1CC11
NM_152498WDR651
NM_152275TTC30A1
NM_006952UPK1B1
NM_000488SERPINC11
NM_182703ANKDD1A1
NM_203364CAPRIN11
NM_021218C9orf801
NM_014299BRD41
NM_001017923C14orf281
NM_0010985001
NM_019590KIAA12171
NM_0010985011
NM_015042ZNF6091
NM_001008397LOC4938691
NM_022650RASA11
NM_002890RASA11
NM_152277UBTD21
NM_0151881
NM_024012HTR5A1
NM_016075VPS361
NM_004782SNAP291
NM_012153EHF1
NM_022763FNDC3B1
NM_004756NUMBL1
NM_052918SORCS11
NM_001013031SORCS11
NM_0011004271
NM_021159RAP1GDS11
NM_0011004281
NM_0011004291
NM_0011004261
NM_0011004301
NM_007175ERLIN21
XM_930431LOC6451951
XM_942574LOC6451951
NM_016061YPEL51
NM_022845CBFB1
NM_001755CBFB1
XM_001126165LOC7279271
NM_002272KRT41
NM_015074KIF1B1
NM_000743CHRNA31
NM_002825PTN1
NM_001002006NT5C1B1
NM_033253NT5C1B1
NM_001009571CADPS21
NM_017954CADPS21
NM_198427BCAN1
NM_001033RRM11
NM_014462LSM11
NM_001077706LFDH1
NM_002738PRKCB11
NM_0011013961
NM_006628ARPP-191
NM_000379XDH1
NM_006777ZBTB331
NM_019062RNF1861
NM_014648DZIP31
NM_144498OSBPL21
NM_014835OSBPL21
NM_152551C6orf1511
NM_012124CHORDC11
NM_021127PMAIP11
XM_001133597LOC7292201
XM_001133619LOC7314431
NM_198506FLJ446911
NM_014335EID11
NM_001037164ARL4A1
NM_005738ARL4A1
NM_212460ARL4A1
NM_000202IDS1
NM_004598SPOCK11
NM_001003682TTMB1
NM_014702KIAA04081
NM_016510SCLY1
NM_017437CPSF21
NM_133646ZAK1
NM_001009569MLLT101
NM_004641MLLT101
XM_001129158LIMS11
NM_017716MS4A121
NM_152866MS4A11
NM_021950MS4A11
NM_017655GIPC21
NM_001079535CPEB11
NM_001079534CPEB11
NM_030594CPEB11
NM_001079533CPEB11
NM_032291SGIP11
NM_016081PALLD1
NM_017798YTHDF11
NM_152778MFSD81
NM_005056JARID1A1
NM_001042603JARID1A1
NM_020405PLXDC11
NM_178834LAYN1
NM_172060EYA11
NM_000503EYA11
NM_172058EYA11
NM_172059EYA11
NM_001732BTN1A11
NM_017847C1orf271
NM_078628MSL3L11
NM_001079846CREBBP1
NM_004380CREBBP1
NM_178496C3orf591
NM_018374TMEM106B1
NM_080660ZC3HAV1L1
NM_182831TNT1
XM_938853LOC2854841
XM_376303LOC2854841
NM_080758TBX61
NM_007344TTF11
NM_017582UBE2Q11
NM_001011722ARHGEF10L1
NM_018125ARHGEF10L1
NM_0142471
NM_015040PIP5K31
NM_012193FZD41
NM_006857RY11
NM_001045478LOC6449971
NM_032049AGTR11
NM_031850AGTR11
NM_004835AGTR11
NM_000685AGTR11
NM_009585AGTR11
NM_018199EXDL21
NM_175854PAN31
NM_004570PIK3C2G1
NM_0011026081
NM_001080975REPS21
NM_004726REPS21
NM_152680TMEM1541
NM_002849PTPRR1
NM_130846PTPRR1
NM_024942C10orf881
NM_003276TMPO1
NM_003287TPD52L11
NM_001003395TPD52L11
NM_001003396TPD52L11
NM_001003397TPD52L11
NM_020750XPO51
NM_001032394GPR1261
NM_020455GPR1261
NM_198569GPR1261
NM_001032395GPR1261
NM_007034DNAJB41
NM_194298SLC16A91
NM_001043352TPM31
NM_001043353TPM31
NM_014733ZFYVE161
NM_0011052511
NM_203451LOC4001201
NM_004253PLAA1
NM_017635SUV420H11
NM_005797EVA11
NM_001045556SLA1
NM_006748SLA1
NM_001045557SLA1
NM_199072MDFIC1
NM_0010996781
NM_017516RAB391
NM_173545C2orf131
NM_001001706FLJ421771
NM_001017963HSP90AA11
NM_005348HSP90AA11
NM_021156TXNDC131
NM_003692TMEFF11
NM_021007SCN2A1
NM_001040142SCN2A1
NM_001040143SCN2A1
NM_033221TRIM141
NM_014788TRIM141
NM_0011055291
NM_006095ATP8A11
NM_021807EXOC41
NM_198281GPRIN31
NM_002076GNS1
NM_001017995SH3PXD2B1
NM_145663DBF4B1
NM_001040214TCBA11
NM_133445GRIN3A1
NM_001011708GTPBP91
NM_013341GTPBP91
NM_015726WDR42A1
NM_016078FAM18B1
NM_007078LDB31
NM_001080114LDB31
NM_012164FBXW21
NM_006282STK41
NM_004359CDC341
NM_000888ITGB61
NM_207009FAM45A1
XM_001130983LOC7318321
NM_018472FAM45B1
NM_006852TLK21
NM_0011127071
NM_194292SASS61
NM_032730RTN4IP11
NM_007270FKBP91
NM_022482GZF11
NM_004896VPS26A1
NM_001035260VPS26A1
NM_021181SLAMF71
NM_144721THAP61
NM_138434C7orf291
XM_059954C9orf571
XM_937019C9orf571
XM_001131206LOC3389631
XM_001130626LOC3389631
NM_005927MFAP31
NM_0208481
NM_207337AMN11
NM_058244WNT8A1
NM_001010984C1orf1241
NM_178527SLC9A111
NM_005599NHLH21
NM_0011110611
XM_001129365LOC7313681
XM_001128918LOC7289611
NM_005238ETS11
NM_014911AAK11
NM_016518PIPOX1
NM_182526C14orf831
NM_030919FAM83D1
NM_138972BACE11
NM_012104BACE11
NM_138973BACE11
NM_138971BACE11
NM_001040402DCUN1D41
NM_015115DCUN1D41
NM_002750MAPK81
NM_139047MAPK81
NM_139046MAPK81
NM_139049MAPK81
NM_021645UTP14C1
NM_006529GLRA31
NM_001042543GLRA31
NM_138737HEPH1
NM_014799HEPH1
NM_000901NR3C21
XM_939208LOC6481491
XM_001133680LOC6481491
NM_015191SNF1LK21
NM_172365C14orf501
NM_0010897041
NM_015646RAP1B1
NM_001010942RAP1B1
NM_005077TLE11
NM_052950WDFY21
NM_001017395TMCC11
NM_015008TMCC11
NM_015141GPD1L1
NM_003772JRKL1
NM_002355M6PR1
NM_198830ACLY1
NM_001096ACLY1
NM_005904SMAD71
NM_005487HMG2L11
NM_014250HMG2L11
NM_001003681HMG2L11
NM_199044NSUN41
NM_152744SDK11
NM_018194HHAT1
NM_014757MAML11
XM_001126853MAML11
NM_007271STK381
NM_020772NUFIP21
NM_152756RICTOR1
NM_176815DHFRL11
NM_017925DENND4C1
NM_015199ANKRD281
NM_000411HLCS1
NM_000809GABRA41
NM_033656BRWD11
NM_005271GLUD11
NM_004411DYNC1I11
NM_013255MKLN11
NM_001031666MS4A31
NM_001031809MS4A31
NM_006138MS4A31
NM_012256ZNF2121
NM_130773CNTNAP51
NM_006558KHDRBS31
NM_175052ST8SIA41
NM_153708RTP11
NM_022100MRPS141
NM_152835PDIK1L1
XM_938665USP6NL1
NM_001080491USP6NL1
XM_927409USP6NL1
XM_943800USP6NL1
NM_006731FCMD1
NM_001079802FCMD1
XM_166659OTUD11
XM_001134465OTUD11
NM_152678FAM116A1
XM_001132771FAM116A1
NM_018700TRIM361
NM_018640LMO31
NM_001001395LMO31
NM_0011003981
NM_015085GARNL41
NM_019050USP531
NM_207437DNAH101
NM_001278CHUK1
NM_001080412ZBTB381
XM_001133510ZBTB381
NM_006980MTERF1
NM_030885MAP41
NM_015161ARL6IP11
NM_016107ZFR1
NM_012325MAPRE11
NM_024948C10orf971
NM_145231C14orf1431
NM_003247THBS21
NM_002846PTPRN1
NM_015902EDD11
XM_937783Rg9mtd11
XM_067605Rg9mtd11
NM_001024843TNRC6B1
NM_015088TNRC6B1
NM_181724TMEM1191
NM_017631FLJ200351
NM_004745DLGAP21
NM_015069ZNF4231
NM_000596IGFBP11
NM_018057SLC6A151
NM_022826MARCH71
NM_173503EFCAB31
NM_0011052071
NM_002290LAMA41
NM_0011052061
NM_000990RPL27A1
NM_134424RAD521
NM_003478CUL51
NM_030915LBH1
XM_001132517LBH1
XM_001132511LBH1
NM_024548LRRIQ21
NM_005156ROD11
NM_032147USP441
NM_001042403USP441
NM_033213ZNF6701
NM_001038603MARVELD21
NM_0011111131
NM_005339HIP21
NM_0011111121
NM_018112TMEM38B1
NM_018048FLJ102921
NM_203395IYD1
NM_006139CD281

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317