Predicted Off-targets for siRNA "gaucaggcaacuauugugg" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

10 hits were found for GAUCAGGCAACUAUUGUGG (9 guide strand hits and 1 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_032373 PCGF5 3668 3686 GuaCAGGCAACUuUUGUGG58 3 9   false   <90%   7179
NM_017990 PDPR 739 757 cccCAGGCAACUgUUGUGG56 4 9   false   <90%   7999
NM_016485 VTA1 629 647 cAUCAGGCAACUAUacUGG47 3 13 c false   <90%   3273
NM_020865 DHX36 2843 2861 GAUCAGGaAACUAUUGcuG11 3 8 c false   <90%   3600
XM_001128636 LOC644397 75 93 uAUguGGCAACUAUUGUGG9 3 14 bc false   <90%   2718
NM_001006607 LRRC37A2 78 96 uAUguGGCAACUAUUGUGG9 3 14 bc false   <90%   5175
NM_014834 LRRC37A 78 96 uAUguGGCAACUAUUGUGG9 3 14 bc false   <90%   5177
NM_199340 LRRC37A3 606 624 uAUguGGCAACUAUUGUGG9 3 14 bc false   <90%   5665
XR_015906 FLJ10120 133 151 uAUguGGCAACUAUUGUGG9 3 14 bc false   <90%   7254


Hits to Sense strand


AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
XM_932802 LOC645307 2174 2192 CCACAAcAGUUGCCUGggg2 4 9 c false   <90%   3875


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1232
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
XM_001125756LOC7277884
NM_033397KIAA17543
NM_018085IPO93
XM_001125734LOC7277813
NM_177457LYNX13
NM_177477LYNX13
NM_177476LYNX13
NM_212467CAPN32
NM_014331SLC7A112
NM_001009899KIAA20182
NM_178010SOX52
NM_006940SOX52
NM_152989SOX52
NM_002081GPC12
NM_020993BCL7A2
NM_001024808BCL7A2
NM_152424FAM123B2
NM_014702KIAA04082
NM_003927MBD22
NM_032738FCRLA2
NM_021809TGIF22
NM_018017C10orf1182
NM_178844NLRC32
NM_145013C11orf452
NM_052916RNF1572
NM_0010992892
NM_006621AHCYL12
NM_207368LOC3482622
NM_0010937672
NM_017712PGPEP12
NM_001029858SLC35F12
NM_004783TAOK22
NM_012072CD932
NM_138473SP12
XM_001133722LOC7317972
NM_017699SIDT12
NM_207577MAP62
NM_006521TFE32
NM_005231CTTN2
NM_138565CTTN2
NM_032457PCDH72
NM_003644GAS72
NM_201432GAS72
NM_201433GAS72
NM_020673RAB22A2
NM_019593KIAA14342
NM_080821C20orf1082
NM_001039771CBLN32
NM_002847PTPRN22
NM_130843PTPRN22
NM_130842PTPRN22
NM_003281TNNI12
NM_001695ATP6V1C12
NM_001029955WDR21B2
NM_001012958DISC12
NM_001010980C1orf1302
NM_001503GPLD11
NM_0011024061
NM_025144ALPK11
NM_182935MOBP1
NM_052885SLC2A131
NM_015137KIAA01431
NM_004999MYO61
NM_080872UNC5D1
NM_033225CSMD11
NM_015457ZDHHC51
NM_012275IL1F51
NM_173170IL1F51
NM_018145FAM82C1
NM_198155C21orf331
NM_004649C21orf331
NM_032208ANTXR11
NM_032012C9orf51
NM_0010997341
NM_052918SORCS11
NM_031417MARK41
NM_057178RFFL1
NM_001017368RFFL1
NM_005169PHOX2A1
NM_0247761
NM_001010987IFIT1L1
NM_006079CITED21
NM_138413C10orf651
NM_212464CAPN31
XM_001129932LOC6453321
NM_152563FAM86C1
NM_018172FAM86C1
NM_0010996531
NM_017709FAM46C1
NM_000240MAOA1
NM_003575ZNF2821
NM_133334WHSC11
NM_000452SLC10A21
NM_030647JHDM1D1
NM_001103ACTN21
NM_013252CLEC5A1
NM_174916UBR11
XM_001128037LOC7286541
XM_001129553LOC7314131
NM_003774GALNT41
XM_378742FLJ459941
XM_943185FLJ459941
NM_024322CENPO1
NM_006974ZNF33A1
NM_006954ZNF33A1
NM_006955ZNF33B1
NM_078476BTN2A11
NM_004992MECP21
NM_024411PDYN1
XM_928464LOC1465171
NM_006203PDE4D1
NM_0011046311
NM_032795RPUSD41
NM_022087GALNT111
NM_001160APAF11
NM_181868APAF11
NM_181869APAF11
NM_013229APAF11
NM_181861APAF11
XM_001128585LOC7306411
NM_004804CIAO11
NM_032960MAPKAPK21
NM_004759MAPKAPK21
NM_000730CCKAR1
NM_001040665STEAP21
NM_152999STEAP21
NM_006310NPEPPS1
NM_004827ABCG21
NM_021813BACH21
NM_007197FZD101
NM_006055LANCL11
NM_002639SERPINB51
NM_024577SH3TC21
NM_031421TTC251
NM_016946F11R1
NM_0011016761
NM_018328MBD51
NM_003425ZNF451
NM_001004316FLJ166411
NM_014369PTPN181
NM_173602DIP2B1
NM_004960FUS1
NM_014648DZIP31
NM_005088CXYorf31
NM_007368RASA31
NM_017991FLJ100811
NM_022776OSBPL111
NM_152835PDIK1L1
NM_199324OTUD41
NM_0011026531
XM_001132288LOC7287161
XM_001134292LOC7322201
NM_012420IFIT51
NM_002518NPAS21
NM_032778MINA1
NM_153182MINA1
NM_001042533MINA1
NM_153218C13orf311
NM_006674HCP51
NM_012233RAB3GAP11
XM_001128878LOC7310521
XM_001128934LOC7287241
NM_018335C14orf1311
NM_003011SET1
NM_0011132391
NM_022740HIPK21
NM_014211GABRP1
NM_016626RKHD21
NM_020905RDH141
NM_015093MAP3K7IP21
NM_032818C9orf1001
NM_144693ZNF5581
NM_152367C1orf1611
NM_020802KIAA13771
NM_015194MYO1D1
NM_152407GRPEL21
NM_032357CCDC1151
NM_207511C9orf1391
NM_016563RASL121
NM_016577RAB6B1
NM_001631ALPI1
NM_002966S100A101
NM_000607ORM11
NM_000608ORM21
NM_005785RNF411
NM_194359RNF411
NM_194358RNF411
NM_001032290PSRC11
NM_001032291PSRC11
NM_032636PSRC11
NM_006306SMC1A1
NM_020774MIB11
XM_001128799MAP3K21
NM_012317LDOC11
NM_0011127411
NM_018312SAPS31
NM_0010854301
NM_006139CD281
NM_005266GJA51
NM_181703GJA51
NM_004193GBF11
NM_030954RNF1701
XM_944029LOC6479791
NM_003023SH3BP21
NM_001039367ATP6V1E11
NM_001696ATP6V1E11
NM_001039366ATP6V1E11
NM_005658TRAF11
NM_001077490GNAS1
NM_016592GNAS1
NM_032793MFSD21
NM_133460ZNF4181
NM_053044HTRA31
NM_024811FLJ125291
NM_032884C1orf941
NM_178427ARNT1
NM_178426ARNT1
NM_001668ARNT1
NM_025107MYCT11
NM_145687MAP4K41
NM_145686MAP4K41
NM_004834MAP4K41
NM_031469SH3BGRL21
XM_001133470LOC7292801
XM_001133468LOC7292801
NM_003948CDKL21
NM_004561OVOL11
XM_001129344OVOL11
NM_004650PNPLA41
NM_000286PEX121
NM_133375DIS3L1
NM_006912RIT11
XM_001134327LOC7323241
XM_001134208LOC7299751
NM_018073TRIM681
NM_018147FAIM1
NM_001033030FAIM1
NM_001033031FAIM1
NM_001033032FAIM1
NM_145165CHURC11
NM_018124RFWD31
NM_001004127ALG111
NM_000869HTR3A1
NM_213621HTR3A1
NM_198484ZNF6211
NM_0010984141
NM_001001712LCN101
NM_183078RNF81
NM_003958RNF81
NM_001455FOXO3A1
NM_201559FOXO3A1
NM_080836STK351
NM_153260LRRC571
XM_933796SLC45A41
XM_944850SLC45A41
NM_001080431SLC45A41
XM_938223LOC1443831
XM_084845LOC1443831
NM_033083EAF11
NM_003382VIPR21
NM_024009GJB31
NM_001005752GJB31
NM_001024668LETMD11
NM_015416LETMD11
NM_144582TEX2611
NM_001013620ALG10B1
NM_152913TMEM1301
XM_943571LOC6469161
NM_017856GEMIN81
NM_001042479GEMIN81
NM_001042480GEMIN81
NM_033109PNPT11
NM_052869TTYH21
NM_032646TTYH21
NM_001031727MGC32071
NM_032285MGC32071
NM_000030AGXT1
NM_001031804MAF1
NM_001040424PRDM151
NM_020132AGPAT31
NM_001037553AGPAT31
NM_012384GMEB21
NM_004468FHL31
NM_025015HSPA12A1
NM_006047RBM121
NM_152838RBM121
NM_033160ZNF6581
NM_001032297ZNF658B1
NM_152751C10orf301
NM_002688SEPT51
NM_007264ADMR1
NM_017909RMND11
NM_170774RASSF21
NM_014737RASSF21
NM_178128FADS61
NM_020353PLSCR41
NM_018509LRRC591
NM_001144AMFR1
XM_001129116MGC396061
XM_001127817MGC396061
NM_207446LOC4004511
NM_022101CXorf561
NM_012298CAND21
NM_021034IFITM31
NM_006435IFITM21
NM_017896C20orf111
NM_173160FXYD41
NM_006933SLC5A31
NM_000115EDNRB1
NM_005239ETS21
XM_001129887TALDO11
NM_024605ARHGAP101
NM_025201PLEKHQ11
NM_021083XK1
NM_001003788LYK51
NM_001003787LYK51
NM_153335LYK51
NM_001003786LYK51
NM_005989AKR1D11
NM_012262HS2ST11
NM_024798SNX221
NM_001406EFNB31
NM_178034PLA2G4D1
NM_020917ZFP141
NM_014023WDR371
NM_182626C2orf481
NM_001031690FAM131B1
NM_014690FAM131B1
XM_944835LOC6486911
NM_032153ZIC41
NM_001795CDH51
NM_015039NMNAT21
NM_170706NMNAT21
NM_015493ANKRD251
NM_020745AARS21
NM_007032TRIOBP1
NM_001039141TRIOBP1
NM_133444ZNF5261
NM_032385C5orf41
NM_0010988191
NM_0010988181
NM_000923PDE4C1
XM_001133595LOC7293241
XM_001133813LOC7317571
NM_015264C22orf91
NM_001009880C22orf91
NM_001042371LOC2838711
NM_030980ISG20L21
NM_017946FKBP141
NM_001017440CALN11
NM_031468CALN11
NM_015074KIF1B1
NM_213597KRBA21
NM_001001561GGA11
NM_032374C14orf1531
NM_024026MRP631
NM_024646ZYG11B1
NM_001040450FAM63B1
NM_001040453FAM63B1
NM_181305MRPL521
NM_181307MRPL521
NM_180982MRPL521
NM_181304MRPL521
NM_178336MRPL521
NM_181306MRPL521
NM_012434SLC17A51
NM_015064ERC11
NM_178039ERC11
NM_178040ERC11
NM_178038ERC11
NM_178037ERC11
NM_174977SEC14L41
NM_017741C4orf301
NM_183397PXMP41
NM_007238PXMP41
NM_032164ZNF3941
XM_929878LOC6469151
NM_0010994551
NM_018340FLJ111511
XM_946265FHAD11
XM_934889FHAD11
NM_001005915ERBB31
NM_021218C9orf801
XM_944654LOC6487161
XM_935966LOC6417981
XM_935369LOC6463291
NM_004348RUNX21
NM_001015051RUNX21
NM_001024630RUNX21
NM_006281STK31
NM_017813IMPAD11
NM_0153061
NM_138493C6orf1291
NM_198098AQP11
NM_0011003881
NM_207430FLJ462661
NM_004894C14orf21
NM_004147DRG11
NM_020956PRX1
XM_943028LOC6477951
NM_012228MSRB21
NM_000831GRIK31
NM_004734DCLK11
XM_001127975FAM66C1
NM_021027UGT1A91
NM_019075UGT1A101
NM_001072UGT1A61
NM_019078UGT1A51
NM_019077UGT1A71
NM_019093UGT1A31
NM_019076UGT1A81
NM_000463UGT1A11
NM_007120UGT1A41
NM_205862UGT1A61
NM_032320BTBD101
NM_003137SRPK11
NM_177550SLC13A51
NM_003898SYNJ21
NM_001003800BICD21
NM_153347TMEM86A1
XM_937430LOC6483771
XM_929253LOC6463161
NM_001523HAS11
NM_152636METT5D11
NM_012064MIP1
NM_052864TIFA1
NM_019857CTPS21
NM_175859CTPS21
XM_378914KIAA04921
XM_944290KIAA04921
NM_017719SNRK1
NM_0011005941
XM_001128662LOC7281921
XM_001133616LOC7318801
NM_000809GABRA41
XM_940318FLJ404111
NM_001080504FLJ404111
NM_0011006261
NM_006459ERLIN11
NM_021943ZFAND31
NM_000466PEX11
NM_173570ZDHHC231
NM_138444KCTD121
NM_021706LAIR11
NM_002287LAIR11
NM_032435KIAA18041
NM_0011004231
NM_0011004221
NM_0011004241
NM_015535LOC260101
XM_942191LOC6446861
NM_025059C6orf971
NM_000833GRIN2A1
NM_024422DSC21
NM_004949DSC21
NM_001024855ZNF1971
NM_181521CMTM41
NM_001033602KIAA07741
NM_015233KIAA07741
NM_024596MCPH11
NM_144684ZNF4801
NM_015042ZNF6091
NM_194318B3GALTL1
NM_005521TLX11
NM_017460CYP3A41
NM_001001668ZNF4701
NM_001079514UBN11
NM_016936UBN11
NM_030636KIAA17061
NM_000128F111
NM_006814PSMF11
NM_178578PSMF11
NM_004285H6PD1
NM_004368CNN21
NM_201277CNN21
NM_005276GPD11
NM_032811TBRG11
NM_004663RAB11A1
NM_198316TENC11
NM_015319TENC11
NM_170754TENC11
NM_001008539SLC7A21
NM_003046SLC7A21
NM_016479SCOTIN1
NM_001017970TMEM30B1
NM_144726RNF1451
NM_001018050POLR3H1
NM_138338POLR3H1
NM_001018052POLR3H1
NM_015086DDN1
NM_031313ALPPL21
NM_182487OLFML2A1
NM_054035UNC1191
NM_005148UNC1191
NM_198686RAB151
NM_178820FBXO271
XM_937528C10orf731
XM_096317C10orf731
NM_000851GSTM51
NM_001202BMP41
NM_130850BMP41
NM_130851BMP41
NM_015187KIAA07461
NM_002906RDX1
NM_005895GOLGA31
NM_032765TRIM521
NM_020662MRS2L1
NM_001042599ERBB41
NM_005235ERBB41
NM_016551TM7SF31
XM_001133017LOC6415151
XM_001132106LOC6415151
NM_020665TMEM271
NM_014034ASF1A1
NM_014636RALGPS11
NM_006160NEUROD21
NM_152320ZNF6411
NM_004707ATG121
NM_138357CCDC109A1
NM_001007139IGF21
NM_000612IGF21
NM_138736GNAO11
NM_145102ZKSCAN51
NM_014569ZKSCAN51
NM_032867MICALCL1
NM_144775SMCR81
NM_015154MESDC21
NM_006813PNRC11
NM_0251851
NM_001537HSBP11
NM_004215EBAG91
NM_198120EBAG91
NM_138468ICA1L1
XM_001131007LOC7296781
XM_001127177LOC7307801
NM_153615Rgr1
NM_017614BHMT21
NM_152630FAM46D1
NM_153036FAM26D1
NM_020742NLGN4X1
NM_181332NLGN4X1
NM_006040HS3ST41
XM_001132212HS3ST41
NM_024689CXorf361
NM_207429FLJ458031
NM_005026PIK3CD1
NM_032376TMEM1011
XM_377073LOC3764751
NM_001001666TMEM16G1
NM_002579PALM1
NM_001040134PALM1
NM_024066PRNPIP1
XM_001132636PRNPIP1
NM_032932RAB11FIP41
NM_025179PLXNA21
NM_170721MSI21
NM_031467SLC4A91
NM_145685BRF11
NM_001519BRF11
NM_020384CLDN21
NM_032296FLYWCH11
NM_198993STAC21
NM_133450ANKS31
NM_001007229SPOP1
NM_001007230SPOP1
NM_001007226SPOP1
NM_003563SPOP1
NM_001007228SPOP1
NM_001007227SPOP1
NM_020245TULP41
NM_001007466TULP41
NM_0011003981
NM_015085GARNL41
NM_022469GREM21
NM_001001694FLJ419931
NM_004238TRIP121
NM_024086METT10D1
NM_005011NRF11
NM_001040110NRF11
NM_003024ITSN11
NM_003993CLK21
XM_933539MGC30321
XM_944529MGC30321
NM_014275MGAT4B1
NM_054013MGAT4B1
NM_014772KIAA04271
NM_001294CLPTM11
NM_001077621VPS37D1
NM_001081492KRT801
XM_001125791LOC6427881
XM_001127886LOC7281001
XM_001132421LOC3883121
XM_943686SYT71
NM_0010998571
NM_003639IKBKG1
NM_0010998561
NM_014376CYFIP21
NM_001037332CYFIP21
NM_001037333CYFIP21
NM_0208271
NM_024641MANEA1
NM_002969MAPK121
XM_001125928LOC2838041
XM_929032LOC6460711
XM_001126277LOC6489131
NM_006861RAB351
NM_015488PNKD1
NM_022572PNKD1
NM_004991MDS11
NM_000744CHRNA41
NM_002522NPTX11
XM_001132528NPTX11
NM_0209101
NM_170601SIAE1
NM_016621PHF21A1
NM_0011018021
NM_032287LDOC1L1
NM_212539PRKCD1
NM_006254PRKCD1
NM_000450SELE1
NM_024705DHRS121
NM_014680KIAA01001
NM_152695ZNF4491
XM_938433C20orf1231
XM_496476C20orf1231
NM_015879ST8SIA31
NM_000214JAG11
NM_000351STS1
NM_000136FANCC1
NM_021095SLC5A61
NM_020692GALNTL11
NM_001008407BCAP291
NM_006564CXCR61
NM_144677MGAT5B1
NM_198955MGAT5B1
NM_015173TBC1D11
NM_003269NR2E11
NM_138284IL17D1
XM_936101LOC6420311
NM_004637RAB7A1
NM_198581ZC3H61
XM_001132378PTP4A21
XM_001132367PTP4A21
XM_001132372PTP4A21
XM_001132369PTP4A21
XM_001132357PTP4A21
NM_144671FAM109A1
NM_001032394GPR1261
NM_020455GPR1261
NM_198569GPR1261
NM_001032395GPR1261
NM_005994TBX21
NM_014909VASH11
NM_022719DGCR141
NM_052943FAM46B1
NM_021615CHST61
NM_015291DNAJC161
NM_023931ZNF7471
NM_001077619LOC1378861
NM_001025780FAM108B11
NM_033224PURB1
NM_014655SLC25A441
NM_181744OPN51
NM_001030051OPN51
NM_153708RTP11
NM_002523NPTX21
NM_145206VTI1A1
NM_024617ZCCHC61
NM_024889C10orf811
NM_021167GATAD11
NM_018952HOXB61
NM_0010853751
NM_020375C12orf51
XM_926793LOC6427571
XM_942502LOC6427571
NM_000310PPT11
NM_012405ICMT1
NM_018298MCOLN31
NM_153020RBM241
NM_145808MTPN1
NM_145207SPATA51
NM_006581FUT91
NM_194071CREB3L21
NM_001040146CTF81
NM_001039690CTF81
NM_001040144CTF81
NM_022914ACD1
NM_001082487ACD1
NM_001082486ACD1
NM_178130TXNDC61
NM_005578LPP1
NM_138563KLK151
NM_001009894C12orf291
NM_199138FAM123A1
NM_152704FAM123A1
NM_139155ADAMTS141
NM_080722ADAMTS141
NM_0011055731
NM_139177SLC39A111
NM_080657RSAD21
NM_178140PDZD21
NM_018941CLN81
XM_001132013ANKH1
NM_182573LYPD51
NM_001031749LYPD51
NM_015299KIAA03231
NM_002885RAP1GAP1
NM_024747HPS61
NM_080491GAB21
NM_012296GAB21
NM_004613TGM21
NM_021815SLC5A71
NM_198859PRICKLE21
NM_183376ARRDC41
NM_145039MGC163851
NM_001013842C8orf581
NM_145912NFAM11
NM_002023FMOD1
NM_020184CNNM41
NM_005632SOLH1
NM_020526EPHA81
NM_002568PABPC11
NM_031459SESN21
NM_001042466PSAP1
NM_002778PSAP1
NM_001042465PSAP1
NM_017707DDEFL11
NM_015202KIAA05561
NM_001070TUBG11
NM_031309SCRT11
NM_147148GSTM41
XM_943975FLJ390801
XM_499117FLJ390801
XM_001128879LOC7289031
NM_031231APBA2BP1
NM_031232APBA2BP1
NM_005433YES11
NM_024817THSD41
NM_006122MAN2A21
NM_173476CCDC781
NM_152455ZSCAN291
NM_032214SLA21
NM_175077SLA21
NM_214677CLEC4M1
NM_214679CLEC4M1
NM_214678CLEC4M1
NM_0151141
NM_020778ALPK31
XM_927712LOC4401041
NM_174929ZMIZ21
NM_031449ZMIZ21
NM_030907C1orf891
NM_005082TRIM251
NM_005894CD5L1
NM_001007102L3MBTL31
NM_032438L3MBTL31
NM_018988GFOD11
NM_001029880SFMBT21
XM_927997LOC6433381
XM_938980LOC6433381
NM_001286CLCN61
NM_152345ANKRD13B1
NM_001018053PFKFB21
NM_000633BCL21
NM_004272HOMER11
NM_004959NR5A11
NM_176792MRPL431
NM_006613GRAP1
NM_015185ARHGEF91
NM_021624HRH41
NM_017812CHCHD31
NM_000121EPOR1
NM_005238ETS11
NM_024815NUDT181
NM_021072HCN11
NM_018566YOD11
NM_021649TICAM21
NM_017510TMED91
NM_012213MLYCD1
NM_016531KLF31
NM_014276RBPJL1
NM_017623CNNM31
NM_199078CNNM31
NM_0321731
NM_178457C20orf1741
NM_181701QSOX21
XM_941162LOC4009501
XM_376049LOC4009501
NM_012338TSPAN121
NM_0207331
NM_203395IYD1
NM_175921LOC2856361
NM_005446P2RXL11
NM_030798WBSCR161
NM_001017403LGR61
NM_021636LGR61
NM_001017404LGR61
NM_015368PANX11
XM_379840LOC4025091
XM_935781LOC4025091
NM_012199EIF2C11
NM_000628IL10RB1
NM_002490NDUFA61
NM_017797BTBD21
NM_000678ADRA1D1
NM_144728DUSP101
NM_007207DUSP101
NM_144729DUSP101
NM_207514FLJ201861
NM_004737LARGE1
NM_133642LARGE1
NM_182686KIAA0319L1
NM_148905OSBPL91
NM_148904OSBPL91
NM_148906OSBPL91
NM_148907OSBPL91
NM_148908OSBPL91
NM_024586OSBPL91
NM_148909OSBPL91
NM_004053BYSL1
NM_001024401SBK11
NM_0010136621
NM_004567PFKFB41
NM_181079IL21R1
NM_021798IL21R1
NM_181078IL21R1
NM_032995ARHGEF41
NM_024627C22orf291
NM_207379TMEM1791
NM_002359MAFG1
NM_032711MAFG1
XM_001134042LOC7320021
NM_000606C8G1
NM_152906C22orf251
NM_001024211S100A131
NM_001024212S100A131
NM_005979S100A131
NM_001024210S100A131
NM_001024213S100A131
NM_0010985091
NM_014853RUTBC11
NM_030630C17orf281
NM_206926SEPN11
NM_020451SEPN11
NM_153611CYBASC31
NM_016233PADI31
NM_020630RET1
XM_938689KIAA16711
XM_371461KIAA16711
NM_003508FZD91
NM_139170C16orf711
NM_001012729DUXA1
XM_498491LOC4399941
XM_930748LOC6423611
XM_001132101LOC7300181
XM_001129006LOC7312641
NM_014008CCDC221
NM_181876PPP2R2C1
NM_020416PPP2R2C1
NM_001423EMP11
NM_018390PLCXD11
NM_000157GBA1
NM_001005742GBA1
NM_001005749GBA1
NM_001005750GBA1
NM_001005741GBA1
NM_030820COL21A11
NM_198836ACACA1
NM_198837ACACA1
NM_198834ACACA1
NM_198838ACACA1
NM_198839ACACA1
NM_144641PPM1M1
NM_001045556SLA1
NM_006748SLA1
NM_001045557SLA1
NM_020679MIF4GD1
NM_001002811PDE4DIP1
NM_001002812PDE4DIP1
XM_001126165LOC7279271
NM_001201BMP31
NM_004175SNRPD31
NM_198511LANCL31
NM_002406MGAT11
NM_153764KCNJ11
NM_153766KCNJ11
NM_000220KCNJ11
NM_153765KCNJ11
NM_153767KCNJ11
NM_018711SVOP1
NM_018662DISC11
NM_001012957DISC11
NM_020708SLC12A51
NM_0011001211
NM_0011001201
NM_014693ECE21
NM_001037324ECE21
NM_002843PTPRJ1
NM_021079NMT11
NM_006320PGRMC21
NM_024677NSUN71
NM_139276STAT31
NM_003150STAT31
NM_213662STAT31
NM_0010986381
NM_000510FSHB1
NM_001018080FSHB1
NM_207349PRR171
NM_001011649CDK5RAP21
NM_018249CDK5RAP21
NM_016156MTMR21
NM_201278MTMR21
NM_201281MTMR21
NM_178026GGTL31
NM_013305ST8SIA51
NM_001001396ATP2B41
NM_001684ATP2B41
NM_002531NTSR11
XM_943043LOC6539041
NM_153451ORAOV11
NM_015077SARM11
NM_020405PLXDC11
NM_006268DPF21
NM_021823PPCDC1
NM_018279TMEM191
NM_0334031
NM_004494HDGF1
XM_941808LOC3998881
XM_374880LOC3998881
NM_012334MYO101
NM_177939PH-41
NM_177938PH-41
NM_198560LHFPL41
NM_015247CYLD1
NM_001042412CYLD1
NM_001042355CYLD1
NM_004055CAPN51
NM_024516C16orf531
NM_001080395AATK1
NM_130783TSPAN181
NM_021648TSPYL41
NM_001040709SYPL21
NM_006606RBBP91
NM_006875PIM21
NM_003900SQSTM11
NM_170740ALDH5A11
NM_001080ALDH5A11
XM_939083TTC281
XM_929318TTC281
NM_198476C19orf541
NM_013245VPS4A1
NM_003436ZNF1351
NM_005870SAP181
NM_006067COX4NB1
XM_001129284LOC7290881
XM_001133596LOC7324301
NM_002677PMP21
NM_014944CLSTN11
NM_001009566CLSTN11
NM_022484TMEM1681
NM_006896HOXA71
NM_194279ISCA21
NM_001079864TAX1BP11
NM_006024TAX1BP11
NM_019604CRTAM1
NM_001002262ZFYVE271
NM_001002261ZFYVE271
NM_144588ZFYVE271
NM_014763MRPL191
NM_194284CLDN231
NM_000201ICAM11
NM_003724JRK1
NM_001712CEACAM11
NM_001024912CEACAM11
NM_004886APBA31
NM_031890CECR61
NM_004205USP21
NM_014347ZNF3241
NM_001080115LDB31
NM_001080116LDB31
NM_003314TTC11
NM_033637BTRC1
NM_003939BTRC1
XM_496436MIA31
XM_932541MIA31
XM_932548MIA31
NM_003417ZNF2641
NM_0010984021
NM_0010984031
NM_020727ZNF2951
NM_198461LONRF21
NM_024707GEMIN71
NM_001007270GEMIN71
NM_001007269GEMIN71
NM_004302ACVR1B1
XM_001134172LOC7300341
XM_001133186LOC7313451
NM_014830ZBTB391
NM_001079877RASA41
NM_006989RASA41
XM_001128325LOC2834811
XM_001133584LOC2834811
NM_001003665C1orf951
XM_928834LOC6458511
XM_940488LOC6458511
NM_020731AHRR1
NM_206866BACH11
NM_001186BACH11
NM_006701TXNL4A1
NM_018273TMEM1431
NM_207395ZNF324B1
NM_001006656ZNF4731
NM_015428ZNF4731
NM_031426C9orf581
XM_001127102LOC6478591
XM_001130815LOC6478591
NM_004386NCAN1
NM_147180PPP3R21
NM_199000LHFPL31
NM_001024688NBN1
NM_002485NBN1
NM_178564NRBP21
NM_177972TUB1
NM_003320TUB1
NM_001001701LOC4011521
NM_153442GPR261
NM_021033RAP2A1
NM_024561NARG1L1
NM_000875IGF1R1
NM_0011110191
NM_145117NAV21
NM_182964NAV21
NM_0011110181
NM_005982SIX11
NM_001042706IQCJ1
NM_207406CCDC41
NM_198896RAB6A1
NM_002869RAB6A1
NM_032144RAB6C1
NM_001077637LOC1507861
NM_005140CNGA21
NM_019001XRN11
NM_001042604XRN11
NM_030934C1orf251
NM_006374STK251
NM_004612TGFBR11
NM_012261C20orf1031
NM_019885CYP26B11
NM_147156SGMS11
NM_152363ANKRD411
NM_199229RPE1
NM_006916RPE1
NM_002577PAK21
NM_014181HSPC1591
NM_003458BSN1
NM_020228PRDM101
NM_199438PRDM101
NM_199437PRDM101
NM_199439PRDM101
NM_018292QRSL11
NM_024511C4orf151
NM_003433ZNF1321
NM_000337SGCD1
NM_016570ERGIC21
NM_019106SEPT31
NM_005458GABBR21
NM_015270ADCY61
NM_020983ADCY61
NM_015166MLC11
NM_139202MLC11
NM_080792SIRPA1
NM_001040023SIRPA1
NM_001040022SIRPA1
NM_004852ONECUT21
NM_002747MAPK41
NM_005460SNCAIP1
NM_000386BLMH1
NM_001039360ZBTB7C1
NM_015595SGEF1
NM_052848CCDC971
NM_021116ADCY11
NM_194317LYPD61
NM_012301MAGI21
NM_012144DNAI11
XM_001128504LOC7310691
NM_015107PHF81
NM_001400EDG11
NM_032559KIF2B1
NM_178834LAYN1
XM_001133858MGC127601
NM_003679KMO1
NM_001080410FBXO411
XM_001133261FBXO411
NM_024522FAM77C1
NM_017654SAMD91
NM_017660GATAD2A1
NM_001001723TMEM11
NM_015645C1QTNF51
NM_001941DSC31
NM_024423DSC31
NM_015346ZFYVE261
NM_001987ETV61
NM_019041MTRF1L1
NM_003476CSRP31
NM_022766CERK1
NM_002737PRKCA1
NM_003215TEC1
NM_001259CDK61
NM_001029871RSPO41
NM_001040007RSPO41
NM_145166ZBTB471
NM_178554KY1
NM_173660DOK71
NM_024551ADIPOR21
NM_018962DSCR61
NM_182520C22orf151
NM_015514NGDN1
NM_012231PRDM21
NM_004209SYNGR31
NM_001017395TMCC11
NM_015008TMCC11
NM_017527LY6K1
NM_003313TSTA31
NM_024909C6orf1341
NM_032207C19orf441
NM_014437SLC39A11
NM_0151641
NM_017893SEMA4G1
NM_015655ZNF3371
NM_033449FCHSD11
NM_182511CBLN21
NM_004273CHST31
NM_024756MMRN21
NM_032899FAM83A1
NM_001010867C1orf691
NM_001076787TP53I111
NM_006034TP53I111
NM_021222PRUNE1
NM_021969NR0B21
NM_0010854291
NM_032966BLR11
NM_001716BLR11
NM_006675TSPAN91
NM_080669SLC46A11
NM_015431TRIM581
NM_002445MSR11
NM_006420ARFGEF21
NM_005551KLK21
NM_001002231KLK21
NM_173829P18SRP1
XM_001129658LOC7292041
XM_001129979LOC7315371
NM_016516VPS541
NM_001005739VPS541
XM_001127417LOC6479091
NM_001001549GRB101
NM_001001555GRB101
NM_001001550GRB101
NM_005311GRB101
NM_001076778FAM107A1
NM_007177FAM107A1
XM_001134215PDPR1
NM_017990PDPR1
NM_020803KLHL81
NM_024761MOBKL2B1
NM_014957DENND31
NM_001018111PODXL1
NM_005397PODXL1
NM_007191WIF11
NM_015423AASDHPPT1
NM_006016CD1641
NM_004331BNIP3L1
NM_000062SERPING11
NM_001032295SERPING11
NM_152437ZNF6641
NM_021205RHOU1
NM_015163TRIM91
NM_001023587ABCC51
NM_018134IQCC1
XM_001126137LOC2849521
XM_001129340LOC2849521
NM_006565CTCF1
NM_0011045461
NM_181724TMEM1191
NM_177965C8orf371
NM_001010888ZC3H12B1
NM_0011001621
NM_0011001611
NM_015024XPO71
NM_0010937251
NM_002334LRP41
XM_930027LOC1512341
XM_938725LOC1512341
NM_014351SULT4A11
NM_001008883CCT31
NM_005998CCT31
NM_001008800CCT31
NM_014587SOX81
NM_005871SMNDC11
NM_016831PER31
NM_175852TXLNA1
NM_145303LOC2024591
NM_005938MLLT71
NM_002039GAB11
NM_207123GAB11
NM_144563RPIA1
NM_015471NSL11
NM_001042549NSL11
NM_005955MTF11
NM_018486HDAC81
NM_207370GPR1531
NM_021954GJA31
NM_0011004171
NM_175748C14orf1301
NM_153035C1orf831
NM_001024843TNRC6B1
NM_015088TNRC6B1
NM_015691WWC31
XM_001132009LOC6468711
XM_929830LOC6468711
NM_006546IGF2BP11
NM_024569MPZL11
NM_003953MPZL11
NM_001014797KCNMA11
NM_0529271
NM_006938SNRPD11
NM_002870RAB131
NM_030772GJA101
NM_145913SLC5A81
NM_033255EPSTI11
NM_001002264EPSTI11
NM_198485FAM79B1

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317