Predicted Off-targets for siRNA "gcauauaugugggcaacua" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

27 hits were found for GCAUAUAUGUGGGCAACUA (1 guide strand hits and 26 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_006952 UPK1B 274 292 GCAUAUuUGUGGGCAuCUg2 3 8 c false   <90%   2060


Hits to Sense strand



























AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_032448 FAM120B 144 162 UAccUGCCCACAUAUAUGu38 3 14 bc false   <90%   3261
XR_016115 LOC653079 121 139 UguUUGgCCACAUAUAUGC2 3 12 bc false   <90%   591
XR_016036 LOC731892 121 139 UguUUGgCCACAUAUAUGC2 3 12 bc false   <90%   591
XR_018788 LOC650225 109 127 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   516
XR_016770 LOC645157 109 127 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   516
XR_015915 LOC729208 120 138 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   519
XR_015894 LOC731456 120 138 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   519
XR_016005 LOC731706 109 127 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   536
XR_016010 LOC729484 109 127 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   537
XM_001127887 LOC728501 122 140 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   570
XM_001126891 LOC730700 122 140 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   570
XM_935700 RPL21 122 140 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   570
XM_001132434 LOC731125 103 121 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   571
XM_928758 LOC653665 103 121 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   571
NM_000982 RPL21 123 141 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   582
XM_001133519 LOC731567 111 129 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   583
XM_001133089 LOC731640 111 129 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   590
XM_370611 LOC387753 123 141 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   601
XM_001133084 LOC731640 123 141 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   601
XM_001133535 LOC729402 131 149 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   602
XM_001133517 LOC731567 131 149 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   603
XM_929340 LOC653737 130 148 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   604
XM_001132436 LOC731125 138 156 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   606
XM_928485 LOC645452 433 451 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   845
XM_939733 LOC650644 433 451 ccuUUGgCCACAUAUAUGC0 4 12 bc false   <90%   845
NM_004136 IREB2 5846 5864 UAGUUGCCugCAUAUAUGg-47 3 8 bc false   <90%   6367


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1529
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_020448NPAL33
NM_003747TNKS3
NM_024665TBL1XR13
NM_001009894C12orf293
NM_001079526IKZF23
NM_016260IKZF23
NM_145259ACVR1C3
NM_0011110313
NM_0011110333
NM_0011110323
NM_175921LOC2856363
XM_928022LOC6449353
XM_001130944LOC6449353
NM_006251PRKAA13
NM_206907PRKAA13
NM_001039580MAP93
NM_002677PMP23
NM_024577SH3TC23
NM_012425RSU12
NM_152724RSU12
NM_002906RDX2
NM_001077440BCLAF12
NM_001077441BCLAF12
NM_014739BCLAF12
NM_006654FRS22
NM_001042555FRS22
NM_174902LDLRAD32
NM_001004313LOC3883352
NM_014089NUPL12
NM_001008564NUPL12
NM_016057COPZ12
NM_031366COL4A32
NM_000091COL4A32
NM_031365COL4A32
NM_031362COL4A32
NM_003246THBS12
NM_145278C1orf1502
NM_015471NSL12
NM_001042549NSL12
NM_001018058TFEC2
NM_012252TFEC2
NM_003155STC12
NM_017752TBC1D8B2
NM_031461CRISPLD12
NM_032983CASP22
NM_018657MYNN2
NM_020157OTOR2
NM_0010996782
NM_182548LHFPL52
NM_005668ST8SIA42
NM_001259CDK62
NM_018698NXT22
NM_133334WHSC12
NM_001656TRIM232
NM_144599NIPA12
NM_004744LRAT2
NM_153183NUDT102
NM_002336LRP62
NM_020233C17orf482
NM_001204BMPR22
NM_018424EPB41L4B2
NM_003838FPGT2
NM_0178922
NM_145913SLC5A82
NM_022091ASCC32
NM_032846RAB2B2
NM_0208552
NM_020868DPP102
NM_001004360DPP102
NM_001039693FLJ379532
NM_005358LMO72
NM_005843STAM22
NM_004161RAB1A2
NM_003421ZNF37A2
NM_001007094ZNF37A2
NM_016052RRP152
NM_001001664LOC3397452
NM_014155ZBTB442
NM_001029863C6orf1202
NM_002111HD2
NM_152774MGC420902
NM_001003406CACNA1I2
NM_021096CACNA1I2
XM_944724LOC6515012
NM_004992MECP22
NM_019096GTPBP22
NM_144684ZNF4802
NM_015569DNM32
NM_014904RAB11FIP22
NM_002035FVT12
NM_033224PURB2
NM_024996GFM12
NM_025113C13orf182
NM_181782NCOA72
NM_032842FLJ148032
NM_019080NDFIP22
NM_006544EXOC52
NM_024512LRRC22
NM_016282AK32
NM_004859CLTC2
NM_0142472
NM_005669REEP52
NM_005233EPHA32
NM_006933SLC5A32
NM_016507CRKRS2
NM_0150832
NM_017583TRIM442
NM_014412CACYBP2
NM_001007214CACYBP2
NM_0011008292
NM_152673MUC202
NM_0010985162
NM_004776B4GALT52
NM_182663RASSF52
NM_182664RASSF52
NM_182665RASSF52
NM_152409C5orf242
NM_020336KIAA12192
NM_001040285PAPD52
NM_001040284PAPD52
NM_002670PLS12
NM_001003679LEPR2
NM_001020658PUM12
NM_014676PUM12
NM_032606CAPS22
NM_005402RALA2
NM_000376VDR2
NM_001017535VDR2
NM_021645UTP14C2
NM_002033FUT42
NM_021912GABRB32
NM_000814GABRB32
NM_001032394GPR1262
NM_020455GPR1262
NM_198569GPR1262
NM_001032395GPR1262
NM_017420SIX42
NM_145257C1orf962
NM_025222TMEM1132
NM_003913PRPF4B2
NM_181527NAT52
NM_181528NAT52
NM_016100NAT52
NM_002040GABPA2
NM_022483C5orf282
NM_181435C1QTNF31
NM_030945C1QTNF31
NM_024419PGS11
NM_005988SPRR2A1
NM_170601SIAE1
NM_020390EIF5A21
NM_134431SLCO1A21
NM_018362LIN7C1
NM_012382TTC331
NM_022458LMBR11
NM_014774KIAA04941
NM_021960MCL11
NM_182763MCL11
NM_024855ACTR51
NM_024942C10orf881
NM_016063HDDC21
NM_017925DENND4C1
NM_0010985001
NM_019590KIAA12171
NM_0010985011
NM_016322RAB141
NM_018566YOD11
NM_178815ARL5B1
NM_152665TCTEX1D11
NM_175854PAN31
NM_181644MFSD41
NM_020783SYT41
NM_003034ST8SIA11
NM_025191EDEM31
NM_170710WDR171
NM_181265WDR171
NM_001083625ANKRD121
NM_015208ANKRD121
NM_152603ZNF5671
NM_001039569AP1S31
NM_004914RAB361
NM_024745SHCBP11
NM_006988ADAMTS11
NM_024989PGAP11
NM_006520DYNLT31
NM_003112SP41
NM_021649TICAM21
NM_006315PCGF31
NM_032160DSEL1
NM_019558HOXD81
NM_002024FMR11
NM_003463PTP4A11
NM_002731PRKACB1
NM_182948PRKACB1
NM_199511CCDC801
NM_199512CCDC801
NM_032664FUT101
NM_004296RGS61
NM_001453FOXC11
NM_001077484SLC38A11
NM_030674SLC38A11
NM_052885SLC2A131
NM_000461THRB1
NM_017546C2orf291
NM_0010994071
NM_015696GPX71
NM_017742ZCCHC21
NM_002878RAD51L31
NM_133629RAD51L31
NM_014746RNF1441
NM_152388ALS2CR41
NM_001044385ALS2CR41
NM_013309SLC30A41
NM_007038ADAMTS51
NM_002207ITGA91
NM_005739RASGRP11
NM_001083112GPD21
NM_000408GPD21
NM_001037535SCML11
NM_001037540SCML11
NM_006746SCML11
NM_001037536SCML11
NM_020353PLSCR41
NM_001001662ZNF7821
NM_006194PAX91
NM_033656BRWD11
XM_938194LOC1276021
XM_059166LOC1276021
NM_173598KSR21
NM_014783ARHGAP11A1
NM_013375ABT11
NM_173167UNC45B1
NM_001033576UNC45B1
XM_931774LOC6437491
XM_944444LOC6437491
NM_152721DOK61
NM_005599NHLH21
NM_0011110611
NM_003016SFRS21
NM_001043318C14orf431
NM_194278C14orf431
NM_012123MTO11
NM_133645MTO11
NM_006775QKI1
NM_014777KIAA01331
NM_001703BAI21
NM_030816ANKRD13C1
NM_006379SEMA3C1
NM_002853RAD11
NM_133377RAD11
NM_006415SPTLC11
NM_005603ATP8B11
NM_152546SRFBP11
NM_007034DNAJB41
NM_153331KCTD61
NM_001014797KCNMA11
NM_001024647RAB3IP1
NM_022456RAB3IP1
NM_175624RAB3IP1
NM_175625RAB3IP1
NM_175623RAB3IP1
NM_000599IGFBP51
NM_203341SEP151
NM_020207C9orf1021
NM_001004328ZNF705A1
NM_032977CASP101
NM_001230CASP101
NM_021639GPBP1L11
NM_021629GNB41
NM_015057MYCBP21
NM_001455FOXO3A1
NM_201559FOXO3A1
NM_014141CNTNAP21
NM_001079512LOC7807761
NM_002357MXD11
NM_007246KLHL21
NM_006022TSC22D11
NM_183422TSC22D11
NM_002527NTF31
NM_0011026541
NM_004434EML11
NM_001008707EML11
NM_152695ZNF4491
NM_032982CASP21
NM_013302EEF2K1
NM_138635H2AFV1
NM_014616ATP11B1
NM_005164ABCD21
NM_001079673FNDC3A1
NM_014923FNDC3A1
NM_001076675ZNF6261
NM_148903GREB11
NM_014630ZNF5921
NM_002486NCBP11
NM_017577GRAMD1C1
NM_001025433NQO11
NM_000903NQO11
NM_001025434NQO11
NM_016531KLF31
NM_144571CNOT6L1
NM_001822CHN11
NM_001025201CHN11
NM_052909KIAA19091
NM_024761MOBKL2B1
NM_145762GFRA41
NM_022139GFRA41
NM_017935BANK11
NM_001083907BANK11
NM_014752SPCS21
NM_002665PLGLB21
NM_001032392PLGLB11
NM_152529GPR1551
NM_001033045GPR1551
NM_033428C9orf1231
NM_020338ZMIZ11
NM_018229C14orf1081
NM_003264TLR21
NM_032408BAZ1B1
NM_001034853RPGR1
NM_019041MTRF1L1
NM_020880ZNF5301
NM_058237KIAA16221
NM_015483KBTBD21
NM_004882CIR1
NM_033227TRIM231
NM_033228TRIM231
NM_022845CBFB1
NM_001755CBFB1
NM_018246CCDC251
NM_001040153SLAIN11
NM_144595SLAIN11
NM_017482ADD21
NM_017484ADD21
NM_001002295GATA31
NM_002051GATA31
NM_014897ZNF6521
NM_006154NEDD41
NM_198400NEDD41
NM_006784WDR31
NM_001079840OCIAD11
NM_001079842OCIAD11
NM_017830OCIAD11
NM_001079839OCIAD11
NM_001079841OCIAD11
NM_181443BTBD31
NM_014962BTBD31
NM_003898SYNJ21
NM_021187CYP4F111
NM_001017395TMCC11
NM_015008TMCC11
NM_032018C1orf1241
NM_001010984C1orf1241
NM_003874CD841
NM_052923ZNF4521
NM_203463LASS61
NM_018317TBC1D191
NM_001025073C3orf171
NM_015412C3orf171
NM_001025072C3orf171
NM_013262MYLIP1
NM_003298NR2C21
NM_007170TESK21
NM_012328DNAJB91
NM_015458MTMR91
NM_002480PPP1R12A1
XM_001131911LOC6459041
XM_938424LOC6459041
XM_928876LOC6459041
NM_000277PAH1
NM_005941MMP161
NM_021940SMAP11
NM_001044305SMAP11
NM_174976ZDHHC221
NM_000092COL4A41
NM_182833GDPD41
NM_033107GTPBP101
NM_001042717GTPBP101
NM_012080HDHD1A1
NM_138347ZNF5511
NM_001083620GRIA21
NM_000826GRIA21
NM_001083619GRIA21
NM_139281WDR361
NM_0010996921
XM_926071LOC6425921
NM_001018108SERF21
XM_001130850LOC6458221
NM_205833IGSF11
XM_291095LOC3399701
XM_943391LOC3399701
NM_001018090Gcom11
NM_001018102GRINL1A1
NM_015532GRINL1A1
NM_001018091Gcom11
NM_052860ZNF3001
NM_014631SH3PXD2A1
XM_927936LOC6448411
XM_935685LOC6419331
XM_938176LOC6448411
NM_152227SNX51
NM_014426SNX51
NM_016002SCCPDH1
NM_015032APRIN1
NM_198881TBC1D8B1
NM_014574STRN31
NM_001083893STRN31
NM_153184CADM21
NM_003476CSRP31
NM_000486AQP21
NM_016586MBIP1
NM_022484TMEM1681
NM_003994KITLG1
NM_000899KITLG1
NM_001031804MAF1
NM_002416CXCL91
NM_002703PPAT1
NM_144722FLJ235771
NM_152636METT5D11
NM_133638ADAMTS191
NM_178539FAM19A21
NM_007149ZNF1841
NM_030754SAA21
NM_016072GOLT1B1
NM_000909NPY1R1
NM_001821CHML1
NM_000925PDHB1
NM_020734FAM80B1
NM_003423ZNF431
NM_182501MTERFD21
NM_016061YPEL51
NM_007050PTPRT1
NM_133170PTPRT1
NM_014418TCL61
NM_020550TCL61
NM_024770METTL81
NM_181489ZNF4451
NM_004237TRIP131
NM_015382HECTD11
NM_003439ZKSCAN11
NM_194291TMEM651
NM_001001684FLJ458311
NM_152355ZNF4411
NM_024641MANEA1
NM_003480MFAP51
NM_133493CD1091
NM_184234RBM391
NM_004902RBM391
NM_0245241
NM_001494GDI21
NM_031458PARP91
NM_002427MMP131
NM_018490LGR41
NM_0011025751
NM_004488GP51
NM_000991RPL281
NM_139163ALS2CR121
NM_005927MFAP31
NM_001008801ZNF4681
NM_199132ZNF4681
NM_170774RASSF21
NM_014737RASSF21
NM_017694FLJ201601
NM_020854KIAA14681
NM_002556OSBP1
NM_021079NMT11
NM_003221TFAP2B1
NM_018466ALG131
NM_000221KHK1
NM_006488KHK1
NM_052932TMEM1231
NM_003099SNX11
NM_152826SNX11
NM_148955SNX11
NM_020141C1orf1191
XM_001125727LOC7277781
XM_001125757LOC7277781
NM_024563C5orf231
XM_943571LOC6469161
NM_173808NEGR11
NM_014750DLG71
NM_000280PAX61
NM_001604PAX61
NM_033515ARHGAP181
XM_001127727LOC7285451
XM_001131957LOC7321351
NM_175871C19orf391
NM_006885ATBF11
NM_022893BCL11A1
NM_005551KLK21
NM_001002231KLK21
NM_004124GMFB1
NM_004748CCPG11
NM_020739CCPG11
NM_007067MYST21
NM_022841RFXDC21
NM_014496RPS6KA61
NM_015172BAT2D11
NM_022454SOX171
NM_014145C20orf301
NM_001009923C20orf301
NM_001009924C20orf301
NM_001009925C20orf301
NM_018299UBE2W1
NM_001001481UBE2W1
NM_004094EIF2S11
NM_006868RAB311
NM_030627CPEB41
NM_012137DDAH11
NM_201999ELF21
NM_006874ELF21
NM_020899ZBTB41
NM_018225SMU11
NM_001033055AIPL11
NM_001033054AIPL11
NM_014336AIPL11
NM_198719PTGER31
NM_000433NCF21
XM_378973LOC2848011
XM_944897LOC2848011
NM_0330261
NM_019854PRMT81
NM_012405ICMT1
NM_032811TBRG11
NM_001007531C6orf1941
NM_198889ANKRD171
NM_032217ANKRD171
NM_017846TRSPAP11
NM_014280DNAJC81
NM_020792AADACL11
NM_002267KPNA31
NM_001011553SEPT71
NM_001788SEPT71
NM_025154UNC84A1
NM_020139BDH21
NM_001025077CUGBP21
XM_001128611LOC7306221
XM_001128643LOC7281141
NM_198151LOC2530121
NM_001039372LOC2530121
XM_941396LOC6520711
NM_001002926TWISTNB1
NM_001029939ZFAT11
NM_032750ABHD14B1
NM_144767AKAP131
NM_006738AKAP131
NM_007200AKAP131
NM_001031710KLHL71
NM_018846KLHL71
XM_944677LOC3387581
XM_931359LOC3387581
NM_015192PLCB11
NM_182734PLCB11
NM_005789PSME31
NM_176863PSME31
NM_198887NUP431
NM_201624USP331
NM_015017USP331
NM_005197CHES11
NM_0010854711
NM_007173PRSS231
NM_032199ARID5B1
NM_198395G3BP11
NM_005754G3BP11
NM_001201BMP31
NM_018195C11orf571
NM_001082969C11orf571
NM_001082970C11orf571
NM_000411HLCS1
NM_198181LOC4402951
XM_001130526LOC7286361
XM_001130555LOC7286361
XM_001130543LOC7286361
XM_001130536LOC7286361
XM_001129399LOC6423461
XM_928707LOC6423461
XM_925879LOC6423461
XM_933066LOC6436961
XM_929030LOC1615271
XM_925864LOC6423251
NM_080629COL11A11
NM_001854COL11A11
NM_080630COL11A11
NM_032689ZNF6071
NM_194285SPTY2D11
NM_014761KIAA01741
NM_203416CD1631
NM_004244CD1631
NM_001040633PRKAG21
NM_016203PRKAG21
NM_024429PRKAG21
NM_001001420SMAD51
NM_001001419SMAD51
NM_005903SMAD51
NM_001682ATP2B11
NM_001001323ATP2B11
NM_020825CRAMP1L1
NM_002581PAPPA1
NM_203395IYD1
NM_017599VEZT1
NM_006033LIPG1
NM_052907TMEM132B1
NM_030971SFXN31
NM_000809GABRA41
XM_936833LOC6441961
XM_927389LOC6441961
NM_018057SLC6A151
NM_001039840CHIC11
NM_032021TMEM1331
NM_178498SLC5A121
NM_001025108AFF31
NM_002285AFF31
NM_006287TFPI1
NM_032532FNDC11
XM_928549LOC6455291
NM_138288C14orf1471
NM_152890COL24A11
NM_144690ZNF5821
NM_152262ZNF4391
NM_000216KAL11
NM_024854FLJ220281
NM_019857CTPS21
NM_175859CTPS21
NM_014554SENP11
NM_152376UBXD31
NM_023000ARID4A1
NM_023001ARID4A1
NM_002892ARID4A1
NM_144980C6orf1181
NM_012257HBP11
NM_053055THEM41
NM_001001931MTUS11
NM_001001924MTUS11
NM_020749MTUS11
NM_001001925MTUS11
NM_173851SLC30A81
NM_003070SMARCA21
NM_139045SMARCA21
NM_030641APOL61
NM_181354OXR11
NM_018298MCOLN31
NM_0010129941
NM_001018065NTRK21
NM_001018066NTRK21
XM_929878LOC6469151
NM_175736FMNL31
NM_198900FMNL31
NM_152233SNX61
NM_021249SNX61
NM_152682RWDD4A1
NM_007275TUSC21
NM_173654C3orf641
NM_016817OAS21
NM_003659AGPS1
NM_002772PRSS71
NM_198467RSBN1L1
NM_020824ARHGAP211
NM_020748INTS21
NM_000362TIMP31
NM_153268PLCXD21
NM_002340LSS1
NM_020909EPB41L51
NM_000046ARSB1
NM_003269NR2E11
NM_014707HDAC91
NM_024875SYNPO2L1
NM_001005337PKP11
NM_000299PKP11
XM_939744LOC6449611
XM_930420LOC6449611
NM_001387DPYSL31
NM_1488931
NM_001004349FLJ454221
NM_024086METT10D1
NM_207378SERPINA131
NM_015040PIP5K31
NM_001856COL16A11
NM_007332TRPA11
NM_018128TSR11
NM_014679CEP571
NM_152347C17orf571
NM_003415ZNF2681
NM_024757EHMT11
NM_198485FAM79B1
NM_145693LPIN11
NM_020940KIAA16001
NM_002745MAPK11
NM_014157CCDC1131
XM_001127710LOC7286531
NM_138554TLR41
NM_174977SEC14L41
NM_001029875RGS7BP1
NM_172364CACNA2D41
NM_032025EIF2A1
NM_173075APBB21
NM_014275MGAT4B1
NM_054013MGAT4B1
NM_007000UPK1A1
NM_207170SYF21
NM_015484SYF21
NM_018211RAVER21
NM_017856GEMIN81
NM_001042479GEMIN81
NM_001042480GEMIN81
NM_152613WBP2NL1
NM_015275KIAA10331
NM_002444MSN1
NM_1736011
NM_0010996501
NM_032458PHF61
NM_001015877PHF61
NM_012338TSPAN121
NM_007107SSR31
NM_003417ZNF2641
NM_024039MIS121
NM_024993LRRTM41
NM_024567HMBOX11
NM_015316PPP1R13B1
NM_014824FCHSD21
NM_024047NUDT91
NM_198038NUDT91
XM_001130020KIAA11471
XM_001130081KIAA11471
NM_001080392KIAA11471
NM_005907MAN1A11
NM_182649PCNA1
NM_002592PCNA1
XM_939100MYO5B1
NM_001080467MYO5B1
NM_001177ARL11
NM_025190KIAA16411
NM_001402EEF1A11
NM_021021SNTB11
NM_014300SEC11A1
NM_001008539SLC7A21
NM_003046SLC7A21
NM_152793C7orf411
NM_004589SCO11
NM_015097CLASP21
NM_017811UBE2R21
NM_012243SLC35A31
NM_020872CNTN31
NM_053002MED12L1
NM_001007097NTRK21
NM_130386COLEC121
NM_0011016761
NM_001017924LRRC221
NM_152606ZNF5401
NM_0010996521
NM_004755RPS6KA51
NM_015156RCOR11
NM_152701ABCA131
NM_017915C12orf481
NM_174908CCDC501
NM_178335CCDC501
NM_173562KCTD201
NM_032105PPP1R12B1
NM_002481PPP1R12B1
NM_006052DSCR31
NM_004397DDX61
NM_153262SYT141
NM_001014372SYT14L1
NM_153810C10orf461
NM_032239LARP21
NM_004898CLOCK1
NM_152896UHRF21
NM_024750LRRC21
NM_002612PDK41
NM_024116JOSD31
NM_181552CUTL11
NM_032193RNASEH2C1
NM_004857AKAP51
NM_024869GRRP11
NM_199229RPE1
NM_004273CHST31
NM_001012393OPCML1
NM_002545OPCML1
NM_173468MOBKL1A1
NM_006991ZNF1971
NM_014423AFF41
NM_005639SYT11
NM_017779DEPDC11
NM_020957PCDHB161
NM_207315LOC1296071
NM_024605ARHGAP101
NM_018590GALNACT-21
NM_015247CYLD1
NM_001042412CYLD1
NM_001042355CYLD1
NM_153022C12orf591
NM_183040DTNBP11
NM_001627ALCAM1
NM_152699SENP51
NM_005504BCAT11
NM_033315RASL10B1
NM_148170CTSC1
NM_018836AJAP11
NM_004956ETV11
NM_006698BLCAP1
NM_173807C1orf1011
NM_198709ARSB1
NM_152605ZNF7811
NM_012249RHOQ1
NM_003565ULK11
XM_001133335ULK11
NM_014817KIAA06441
NM_012464TLL11
NM_001039762FLJ455571
NM_021130PPIA1
NM_001946DUSP61
NM_022652DUSP61
NM_000250MPO1
NM_005937MLLT61
NM_153447NLRP51
XM_001132925DUSP221
NM_005400PRKCE1
NM_0010996661
NM_021963NAP1L21
NM_004929CALB11
NM_013381TRHDE1
NM_005253FOSL21
NM_018133MSL2L11
NM_001083924C1orf1161
NM_023938C1orf1161
NM_018364RSBN11
NM_001357DHX91
NM_1827627A51
NM_021970MAP2K1IP11
NM_001002247ANAPC111
NM_001002248ANAPC111
NM_016476ANAPC111
NM_001002249ANAPC111
NM_001002245ANAPC111
NM_001002246ANAPC111
NM_001002244ANAPC111
XM_001133283LOC7289191
XM_001133292LOC7289191
XM_001133288LOC7289191
XM_001133297LOC7289191
NM_020766PCDH191
NM_0011052431
NM_016195MPHOSPH11
NM_080628C20orf1181
NM_144664FAM76B1
NM_004484GPC31
NM_032873STS-11
NM_003342UBE2G11
NM_024754PTCD21
NM_152238SNX71
NM_015976SNX71
NM_014829DDX461
NM_147192DMBX11
NM_172225DMBX11
NM_003901SGPL11
NM_012175FBXO31
NM_175898C15orf371
NM_033214GK21
NM_020337ANKRD501
NM_022459XPO41
NM_0155621
NM_0010400611
NM_145701CDCA41
NM_017955CDCA41
NM_144617HSPB61
NM_000953PTGDR1
NM_020932MAGEE11
NM_012224NEK11
NM_006047RBM121
NM_152838RBM121
NM_020673RAB22A1
NM_016133INSIG21
NM_030650KIAA17151
NM_207015NAALADL21
NM_004879EI241
NM_001007277EI241
NM_005066SFPQ1
NM_022116FIGNL11
NM_001042762FIGNL11
NM_017991FLJ100811
NM_007021C10orf101
NM_007144PCGF21
NM_032735BEST31
NM_152439BEST31
XM_001133760ZNF5191
NM_005056JARID1A1
NM_001042603JARID1A1
NM_006016CD1641
NM_145011ZNF251
NM_016351ADAM221
NM_021723ADAM221
NM_021722ADAM221
NM_002241KCNJ101
NM_199320PHF171
NM_018999KIAA11281
XM_001126392LOC7279091
XM_001126407LOC7279091
XM_001126378LOC7279091
NM_030761WNT41
XM_001132247C1orf1081
NM_003887DDEF21
NM_022374ARL6IP21
NM_007353GNA121
NM_001083592ROR11
NM_018247TMEM30A1
NM_003559PIP5K2B1
NM_000321RB11
XM_001126290LOC7279081
NM_002223ITPR21
NM_012120CD2AP1
NM_002210ITGAV1
NM_015070ZC3H131
NM_006319CDIPT1
XM_001132516LOC7290491
XM_001128311LOC7314491
XM_001129750LOC7289991
NM_198491FAM92B1
NM_0190901
NM_033087ALG21
NM_182703ANKDD1A1
NM_152423MUM1L11
NM_005493RANBP91
NM_001024943ASL1
NM_001024946ASL1
NM_001024944ASL1
NM_000048ASL1
NM_014838ZBED41
NM_001013406KRIT11
NM_004912KRIT11
NM_194454KRIT11
NM_194456KRIT11
NM_194455KRIT11
NM_032457PCDH71
NM_004290RNF141
NM_183400RNF141
NM_183398RNF141
NM_183401RNF141
NM_183399RNF141
NM_207361FREM21
NM_022473ZFP1061
NM_001921DCTD1
NM_001012732DCTD1
XM_939750USP321
NM_032582USP321
NM_013438UBQLN11
NM_052880PIK3IP11
NM_018032LUC7L1
NM_017719SNRK1
NM_0011005941
NM_001001668ZNF4701
NM_014606HERC31
NM_004815ARHGAP291
NM_0010983981
NM_004371COPA1
NM_138738FCRL21
NM_030764FCRL21
NM_001012515FECH1
NM_000140FECH1
NM_198904GABRG21
XM_931447SETD51
XM_944298SETD51
XM_944295SETD51
XM_931444SETD51
NM_019006ZFAND61
NM_015272KIAA10051
NM_014733ZFYVE161
NM_0011052511
NM_025221KCNIP41
NM_001035003KCNIP41
NM_001035004KCNIP41
NM_147183KCNIP41
NM_147182KCNIP41
NM_147181KCNIP41
NM_015087SPG201
NM_0010999521
NM_002222ITPR11
NM_144578C14orf321
NM_003385VSNL11
NM_182540DDX26B1
NM_024896KIAA18151
NM_173833SCARA51
NM_021163RBAK1
NM_015520MAGI11
NM_001033057MAGI11
XM_928464LOC1465171
NM_152446C14orf1451
NM_173464L3MBTL41
NM_030780SLC25A321
NM_0010937261
NM_0010854861
NM_005410SEPP11
NM_017845COMMD81
NM_023016ANKRD571
XM_166659OTUD11
XM_001134465OTUD11
NM_014826CDC42BPA1
NM_003607CDC42BPA1
NM_153712TTL1
NM_001024843TNRC6B1
NM_015088TNRC6B1
NM_001013620ALG10B1
NM_003452ZNF1891
NM_197977ZNF1891
NM_002019FLT11
NM_004731SLC16A71
NM_021083XK1
NM_017684VPS13C1
NM_020821VPS13C1
XM_944271USP451
XM_939661USP451
XM_944273USP451
XM_944255USP451
XM_931094USP451
XM_931124USP451
XM_931115USP451
NM_001080481USP451
NM_015387PREI31
NM_199482PREI31
NM_0011008191
NM_018157RIC8B1
NM_001045SLC6A41
NM_015365AMMECR11
NM_001025580AMMECR11
NM_020794LRRC71
NM_178130TXNDC61
NM_020699GATAD2B1
NM_014058TMPRSS11E1
NM_0010996621
NM_017590ZC3H7B1
NM_014850SRGAP31
NM_001033117SRGAP31
NM_032558HIATL11
NM_032486DCTN51
NM_001001436LOC3882721
NM_014149HSPC0491
NM_001037631CTLA41
NM_005214CTLA41
NM_000428LTBP21
NM_206853QKI1
NM_206854QKI1
NM_206855QKI1
NM_001006657WDR351
NM_020779WDR351
NM_032810ATAD11
NM_003408ZFP371
NM_003850SUCLA21
NM_033222PSIP11
NM_032521PARD6B1
NM_000950PRRG11
NM_005068SIM11
NM_014035SNX241
NM_138731MIPOL11
NM_001010874SRD5A2L21
NM_152261C12orf231
NM_017645FAM29A1
NM_000493COL10A11
NM_016108AIG11
XM_001131899LOC2839041
NM_001167BIRC41
NM_015506MMACHC1
NM_001754RUNX11
NM_001001890RUNX11
NM_016081PALLD1
NM_017516RAB391
NM_001017970TMEM30B1
NM_145207SPATA51
NM_022843PCDH201
NM_015886PI151
NM_001033910TRAF51
NM_145759TRAF51
NM_004619TRAF51
NM_173665C5orf361
NM_007147ZNF1751
NM_003262TLOC11
XM_376795FLJ458721
XM_940037FLJ458721
NM_194292SASS61
NM_024420PLA2G4A1
NM_181836TMED71
NM_003630PEX31
NM_177996EPB41L11
NM_012156EPB41L11
NM_001002860BTBD71
NM_006282STK41
NM_145176SLC2A121
NM_002445MSR11
NM_213595ISCU1
NM_014301ISCU1
NM_032242PLXNA11
NM_016138COQ71
NM_022977ACSL41
NM_004458ACSL41
NM_006011ST8SIA21
NM_016631C21orf661
NM_017813IMPAD11
NM_005449FAIM31
NM_153453VGLL21
NM_182645VGLL21
NM_016224SNX91
NM_001040441ZBTB81
XM_001124597LOC7304111
NM_177422EIF2C31
NM_024852EIF2C31
NM_006955ZNF33B1
NM_019063EML41
NM_016551TM7SF31
NM_080764SUHW21
NM_017665ZCCHC101
NM_005192CDKN31
NM_173825RABL31
XM_926634LOC6532561
NM_022121PERP1
NM_032943SYTL21
NM_206929SYTL21
NM_206930SYTL21
NM_206927SYTL21
NM_032379SYTL21
NM_206928SYTL21
NM_005966NAB11
NM_015191SNF1LK21
NM_181705LYRM71
NM_005680TAF1B1
NM_014877HELZ1
NM_004348RUNX21
NM_001015051RUNX21
NM_001024630RUNX21
NM_025214CCDC681
NM_015349KIAA02401
NM_138448ACYP21
NM_014034ASF1A1
NM_020774MIB11
NM_052917GALNT131
NM_015138RTF11
NM_006366CAP21
NM_0011001591
NM_173829P18SRP1
NM_0151771
NM_006945SPRR2D1
NM_006136CAPZA21
NM_000112SLC26A21
NM_018640LMO31
NM_001001395LMO31
NM_003829MPDZ1
NM_0011004171
NM_175748C14orf1301
NM_006255PRKCH1
XM_942958LOC6422361
XM_943005LOC6422361
XM_001126144LOC7305101
NM_0010985251
NM_018204CKAP21
NM_014910ZNF5071
XM_001133364LOC7295331
XM_001133363LOC7295331
XM_001133365LOC7295331
NM_207418FAM72A1
NM_0011009101
NM_006300ZNF2301
NM_005230ELK31
NM_005465AKT31
NM_018243SEPT111
NM_015396ARMC81
NM_177424STX121
NM_001003652SMAD21
NM_005901SMAD21
NM_198511LANCL31
NM_173473C10orf1041
NM_153688ZFP11
NM_001037163MGC129661
NM_001042413GLIS31
NM_152629GLIS31
NM_016065MRPS161
NM_001012977LOC3405291
NM_005509DMXL11
NM_002900RBP31
NM_024408NOTCH21
XM_001133349NOTCH21
NM_006246PPP2R5E1
NM_174924PDILT1
NM_173699MAGEB181
NM_001014380KATNAL11
NM_032116KATNAL11
NM_178136POLDIP31
NM_032311POLDIP31
NM_014629ARHGEF101
NM_025160WDR261
NM_030806C1orf211
NM_001042520MGC130571
NM_001042521MGC130571
NM_001042519MGC130571
NM_032321MGC130571
NM_032682FOXP11
NM_014358CLEC4E1
NM_024808C13orf341
NM_001530HIF1A1
NM_181054HIF1A1
NM_017945SLC35A51
NM_016319COPS7A1
NM_016383LUZP41
NM_017831RNF1251
NM_015385SORBS11
NM_001034954SORBS11
NM_001034957SORBS11
NM_001034955SORBS11
NM_001034956SORBS11
NM_006434SORBS11
NM_024991SORBS11
XM_379078FLJ414811
XM_944401FLJ414811
NM_0209231
NM_005491CXorf61
NM_001977ENPEP1
NM_012129CLDN121
NM_138806CD200R11
NM_170780CD200R11
NM_001040694INCENP1
NM_020238INCENP1
NM_002736PRKAR2B1
NM_152758YTHDF31
NM_024900PHF171
NM_1829691
XM_378914KIAA04921
XM_944290KIAA04921
XM_001127437LOC7308391
NM_001009931HRNR1
XM_941105LOC1525731
NM_001080505LOC1525731
NM_017704ANKRD491
NM_006635ZNF4601
NM_005476GNE1
NM_032228MLSTD21
NM_006197PCM11
NM_198271LMOD31
NM_001002762DNAJB121
NM_017626DNAJB121
NM_002645PIK3C2A1
NM_001417EIF4B1
NM_017988SCYL21
NM_001001701LOC4011521
NM_021998ZNF7111
NM_000833GRIN2A1
NM_005108XYLB1
NM_130898CREB3L41
NM_0010854471
NM_003352SUMO11
NM_001005782SUMO11
NM_001005781SUMO11
NM_002006FGF21
NM_005737ARL4C1
NM_016124RHD1
NM_003500ACOX21
NM_001025300RAB121
NM_203371LOC3877581
NM_015176FBXO281
NM_177951PPM1A1
NM_173694ATP11C1
NM_001010986ATP11C1
NM_021045ZNF2481
NM_021823PPCDC1
NM_000387SLC25A201
XM_001133926SLC25A201
NM_005999TSNAX1
NM_016217HECA1
NM_004175SNRPD31
NM_005385NKTR1
NM_0010986241
NM_033290MID11
NM_000381MID11
NM_014573TMEM971
NM_198281GPRIN31
NM_006753SURF61
NM_020403PCDH91
NM_203487PCDH91
NM_014190ADD11
NM_001119ADD11
NM_014189ADD11
NM_176801ADD11
NM_002526NT5E1
NM_032494ZC3H81
NM_138286ZNF6811
NM_014744TBC1D51
NM_174959SVOPL1
NM_212555C11orf381
NM_0010996791
NM_012210TRIM321
NM_004136IREB21
NM_012228MSRB21
NM_001042599ERBB41
NM_005235ERBB41
NM_022828YTHDC21
NM_177925H2AFJ1
NM_133375DIS3L1
NM_014368LHX61
NM_199160LHX61
NM_000632ITGAM1
NM_173645FLJ373571
NM_181502SPINLW11
NM_020398SPINLW11
NM_000266NDP1
NM_033495KLHL131
NM_213598ZNF5431
NM_0011001641
NM_0011001661
NM_014721PHACTR21
NM_0011001651
NM_0321841
NM_005845ABCC41
XM_379636C9orf1221
XM_940165C9orf1221
NM_0010996381
NM_0010996391
NM_007145ZNF1461
NM_020150SAR1A1
NM_015265SATB21
NM_198098AQP11
NM_052941GBP41
NM_194247HNRPA31
NM_021020LZTS11
NM_015144ZCCHC141
NM_025187C16orf701
NM_000831GRIK31
NM_005810KLRG11
NM_0010992671
NM_198503KCNT21
NM_019069WDR5B1
NM_214711LOC4011371
NM_006595API51
NM_005433YES11
NM_182962BIRC31
NM_001165BIRC31
NM_138999NETO11
NM_182523MGC615711
NM_018489ASH1L1
NM_212558LOC4014981
NM_032778MINA1
NM_153182MINA1
NM_001042533MINA1
NM_006419CXCL131
NM_174878CLRN11
NM_138426GLCCI11
NM_199324OTUD41
NM_0011026531
NM_014331SLC7A111
NM_001008393LOC2017251
NM_016519AMBN1
NM_004820CYP7B11
NM_000673ADH71
NM_207647FSD1L1
NM_0010854601
NM_0010854691
NM_0010854651
NM_0010854661
NM_0010854621
NM_0010854611
NM_0010854581
NM_0010854681
NM_0010854631
NM_0010854671
NM_001331CTNND11
NM_0010854591
NM_0010854641
NM_006145DNAJB11
XM_379100LOC4009581
XM_945436LOC4009581
NM_000332ATXN11
NM_052954CYYR11
NM_015571SENP61
NM_0011004091
NM_002563P2RY11
NM_001013659ZNF7931
NM_181783TMTC31
NM_206866BACH11
NM_001186BACH11
NM_015132SNX131
NM_006380APPBP21
NM_203418DSCR11
NM_203417DSCR11
NM_004414DSCR11
NM_006581FUT91
NM_006914RORB1
NM_006444SMC21
NM_001042550SMC21
NM_001042551SMC21
NM_020424LYRM11
NM_001009899KIAA20181
NM_207578PRKACB1
NM_016529ATP8A21
NM_138718SLC26A81
NM_052961SLC26A81
NM_207037TCF121
NM_003205TCF121
NM_207040TCF121
NM_207036TCF121
NM_207038TCF121
NM_173582PGM2L11
NM_017641KIF21A1
NM_033426KIAA17371
NM_019892INPP5E1
NM_174916UBR11
NM_012275IL1F51
NM_173170IL1F51
NM_020922WNK31
NM_001002838WNK31
NM_006827TMED101
NM_003642HAT11
NM_001033085HAT11
NM_0010087811
XM_936538FAT31
XM_926199FAT31
NM_198124CSMD31
NM_198123CSMD31
NM_052900CSMD31
NM_001560IL13RA11
NM_153825SLA/LP1
NM_153188TNPO11
NM_002270TNPO11
NM_014819PJA21
NM_016388TRAT11
NM_032189ATP11A1
NM_015205ATP11A1
NM_005651TDO21
NM_001040665STEAP21
NM_152999STEAP21
NM_181742ORC4L1
NM_002552ORC4L1
NM_181741ORC4L1
NM_017672TRPM71
NM_152857WTAP1
NM_152858WTAP1
NM_152436GLIPR1L21
NM_000926PGR1
XM_001133421LOC7317741
XM_001132470LOC7290701
NM_030959OR12D31
NM_032091PCDHGA111
XM_936878DKFZP781G01191
XM_927284DKFZP781G01191
NM_000291PGK11
NM_032547SCOC1
NM_014926SLITRK31
XM_001128878LOC7310521
XM_001128934LOC7287241
NM_0011052821
NM_178509STXBP41
NM_019899ABCC11
NM_019862ABCC11
NM_019898ABCC11
NM_004996ABCC11
NM_019900ABCC11
NM_005756GPR641
NM_001079859GPR641
NM_001079858GPR641
NM_001079860GPR641
NM_180991SLCO4C11
NM_006614CHL11
NM_138335GNPDA21
NM_019106SEPT31
XM_939083TTC281
XM_929318TTC281
NM_017755NSUN21
NM_020718USP311
XM_945219LOC2198541
XM_933919LOC2198541
XM_933894LOC2198541
XM_945207LOC2198541
XM_945208LOC2198541
XM_945220LOC2198541
XM_933911LOC2198541
XM_945215LOC2198541
NM_001080546LOC2198541
XM_945222LOC2198541
XM_933914LOC2198541
XM_166164LOC2198541
XM_933905LOC2198541
XM_941442LOC2198541
NM_001277CHKA1
NM_212469CHKA1
NM_016613C4orf181
NM_152756RICTOR1
NM_003927MBD21
NM_001011720XKR91
NM_001037293PALM21
NM_053016PALM21
XM_001128616LOC4010211
NM_021116ADCY11
NM_173487C4orf331
NM_0010997831
NM_178457C20orf1741
NM_015375RIPK51
NM_199462RIPK51
NM_032471PKIB1
NM_181795PKIB1
NM_181794PKIB1
NM_020753CASKIN21
NM_003664AP3B11
XM_374260LOC3896411
XM_944097LOC3896411
NM_003029SHC11
NM_207009FAM45A1
NM_007080LSM61
NM_005123NR1H41
NM_182700SP81
NM_198956SP81
NM_021982SEC24A1
NM_032042C5orf211
NM_198077C1orf521
NM_020474GALNT11
NM_033034TRIM51
NM_033093TRIM51
NM_004686MTMR71
NM_012297G3BP21
NM_203504G3BP21
NM_203505G3BP21
NM_005375MYB1
NM_006777ZBTB331
NM_001042486DLGAP41
NM_014902DLGAP41
NM_183006DLGAP41
NM_153018ZFP31
NM_0011031471
NM_0011031481
NM_0011031461
NM_015575TNRC151
NM_005124NUP1531
NM_022140EPB41L4A1
NM_030762BHLHB31
NM_001481GAS81
NM_001004317LIN28B1
NM_005644TAF121
NM_020802KIAA13771
NM_014903NAV31

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317