Predicted Off-targets for siRNA "gcaucauaaccauauggua" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
Warning - siRNA is specific for only the antisense (guide) strand

12 hits were found for GCAUCAUAACCAUAUGGUA (4 guide strand hits and 8 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_018269 ADI1 238 256 aCAUCAUAACCAUAUGcaA71 3 15 ac false   <90%   1628
NM_198395 G3BP1 2684 2702 aaAUCAUAgCCAUAUGGUA26 3 10 bc false   <90%   2824
NM_005754 G3BP1 2715 2733 aaAUCAUAgCCAUAUGGUA26 3 10 bc false   <90%   2855
NM_012214 MGAT4A 276 294 uCAUCAUAAaCAUAUGGac7 4 8 c false   <90%   8382


Hits to Sense strand









AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_173635 FLJ40235 306 324 aACCAUAUGGUUcUGAUGu82 3 11   false   <90%   1706
NM_138821 PAM 1435 1453 UcugAUAUGGUUAUGAUGC32 3 15 bc false   <90%   3636
NM_138822 PAM 1435 1453 UcugAUAUGGUUAUGAUGC32 3 15 bc false   <90%   3699
NM_138766 PAM 1435 1453 UcugAUAUGGUUAUGAUGC32 3 15 bc false   <90%   3753
NM_000919 PAM 1435 1453 UcugAUAUGGUUAUGAUGC32 3 15 bc false   <90%   3960
NM_012327 PIGN 839 857 auaCAUAUaGUUAUGAUGC6 4 10 bc false   <90%   4816
NM_176787 PIGN 916 934 auaCAUAUaGUUAUGAUGC6 4 10 bc false   <90%   4893
NM_175907 ZADH2 3985 4003 UACCAUuUGGUUAUGAcuu2 4 9 c false   <90%   4132


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1480
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_017644KLHL243
NM_007249KLF123
NM_012164FBXW23
NM_001009909LUZP23
NM_017759FLJ203093
NM_152835PDIK1L3
NM_002221ITPKB3
NM_001076786QSER12
NM_020390EIF5A22
NM_080872UNC5D2
NM_152866MS4A12
NM_021950MS4A12
NM_176081TRDMT12
NM_004412TRDMT12
NM_176083TRDMT12
NM_001626AKT22
NM_016079VPS242
NM_001005753VPS242
NM_024052C17orf392
NM_015156RCOR12
NM_014830ZBTB392
NM_001278CHUK2
NM_001204BMPR22
NM_213609FAM19A12
NM_052898XKR42
NM_018940PCDHB72
NM_024345WDR322
NM_004264SURB72
NM_207361FREM22
NM_002604PDE7A2
NM_0333902
XM_944900LOC6437702
XM_931792LOC6437702
NM_014240LIMD12
NM_004852ONECUT22
NM_172318KCNG12
NM_006775QKI2
NM_014864FAM20B2
NM_153705KDELC22
NM_015286DMN2
NM_145728DMN2
NM_152854CD402
NM_001250CD402
NM_173562KCTD202
NM_138793CANT12
NM_014331SLC7A112
NM_198399ARPP-212
NM_001025069ARPP-212
NM_001025068ARPP-212
NM_032458PHF62
NM_152424FAM123B2
NM_021629GNB42
NM_001776ENTPD12
NM_0010981752
NM_172128CAMK2D2
NM_172127CAMK2D2
NM_206925CA122
NM_001218CA122
NM_001010846SHE2
NM_017754C6orf1072
NM_001077484SLC38A12
NM_030674SLC38A12
NM_001001343MGC271212
NM_024837ATP8B42
NM_058170OLFM32
NM_001037293PALM22
NM_053016PALM22
NM_001042383CEP632
NM_001042400CEP632
NM_025180CEP632
NM_003149STAC2
XM_001133837LOC7320992
XM_001133987LOC7296812
NM_016156MTMR22
NM_201278MTMR22
NM_201281MTMR22
NM_024577SH3TC22
NM_019083CCDC762
NM_001035513SDHC2
NM_001035512SDHC2
NM_003001SDHC2
NM_153365TAPT12
NM_001002860BTBD72
NM_015326SRGAP22
XM_938689KIAA16712
XM_371461KIAA16712
NM_207454FLJ448152
NM_015533DAK2
NM_007271STK382
NM_003298NR2C22
NM_020760HECW22
NM_024761MOBKL2B2
NM_007270FKBP92
NM_153442GPR262
NM_002033FUT42
NM_181489ZNF4452
NM_153256C10orf472
NM_017415KLHL32
NM_004171SLC1A22
NM_004859CLTC2
NM_018566YOD12
NM_001042574CRTC32
NM_022769CRTC32
NM_001005210LRRC552
XM_001133760ZNF5192
NM_015328KIAA08282
NM_003387WIPF12
NM_001077269WIPF12
NM_006166NFYB2
NM_207444FLJ356951
NM_004991MDS11
NM_003762VAMP41
NM_171982TRIM351
XM_941142FTO1
NM_001080432FTO1
NM_002993CXCL61
NM_144964RG9MTD31
NM_001077700MIER11
NM_001077701MIER11
NM_020948MIER11
NM_003256TIMP41
NM_022091ASCC31
XM_209597LOC2854071
XM_939967LOC2854071
XM_001126071LOC7304901
XM_001130605LOC7295561
NM_014106ZNF7701
NM_0152041
NM_139177SLC39A111
NM_014637MTFR11
NM_006754SYPL11
NM_182715SYPL11
NM_194272RBPMS21
NM_004273CHST31
NM_138426GLCCI11
NM_144632TMEM1821
NM_0229061
NM_030576LIMD21
NM_018370DRAM1
NM_002053GBP11
NM_018284GBP31
NM_000390CHM1
NM_175078KRT771
NM_000189HK21
NM_152760FLJ309341
NM_004667HERC21
NM_017738C9orf391
NM_015419MXRA51
NM_173552C3orf581
NM_003045SLC7A11
NM_024087ASB91
NM_006136CAPZA21
NM_030647JHDM1D1
NM_002877RAD51L11
NM_0010853681
NM_001009960ZNF6551
NM_0010839561
NM_138494ZNF6551
NM_006113VAV31
NM_001079874VAV31
NM_017776ZNF6731
NM_022374ARL6IP21
NM_0011111131
NM_005339HIP21
NM_0011111121
NM_020353PLSCR41
NM_002015FOXO1A1
NM_000544TAP21
NM_030787CFHR51
NM_001040450FAM63B1
NM_001040453FAM63B1
NM_021128POLR2L1
NM_001009554MFAP3L1
NM_021647MFAP3L1
NM_178566ZDHHC211
NM_017651AHI11
NM_001013406KRIT11
NM_004912KRIT11
NM_194454KRIT11
NM_194456KRIT11
NM_194455KRIT11
NM_022351EFCBP11
NM_020673RAB22A1
NM_032980DTNA1
NM_001390DTNA1
NM_032975DTNA1
NM_033027AXUD11
NM_153711FAM26E1
NM_006187OAS31
NM_198581ZC3H61
NM_021628ALOXE31
NM_001030006AP2B11
NM_001282AP2B11
NM_139076CCDC981
XM_001127175LOC7283201
NM_032446MEGF101
NM_001014380KATNAL11
NM_032116KATNAL11
NM_1779662'-PDE1
NM_080760DACH11
NM_080759DACH11
NM_004392DACH11
NM_133328DEDD21
NM_147202C9orf251
NM_0010854511
NM_138318KCNK101
NM_138317KCNK101
NM_021161KCNK101
NM_004598SPOCK11
NM_002655PLAG11
NM_018899PCDHAC21
NM_018900PCDHA11
NM_018902PCDHA111
NM_031849PCDHA61
NM_018905PCDHA21
NM_018904PCDHA131
NM_031860PCDHA101
NM_018907PCDHA41
NM_018909PCDHA61
NM_018910PCDHA71
NM_018911PCDHA81
NM_018906PCDHA31
NM_018903PCDHA121
NM_018898PCDHAC11
NM_031857PCDHA91
NM_031411PCDHA11
NM_018908PCDHA51
NM_018901PCDHA101
NM_176815DHFRL11
NM_0010895951
NM_001039802CDC421
NM_001791CDC421
NM_001982ERBB31
NM_033035TSLP1
NM_138551TSLP1
NM_001167BIRC41
NM_000891KCNJ21
NM_004978KCNC41
NM_014035SNX241
NM_001013650LOC3891511
NM_171998RAB39B1
NM_145687MAP4K41
NM_145686MAP4K41
NM_004834MAP4K41
NM_177457LYNX11
NM_177477LYNX11
NM_177476LYNX11
NM_172212CSF11
XM_001133620LOC7318951
NM_001080396LOC7282151
NM_173851SLC30A81
NM_016937POLA11
NM_003472DEK1
XM_001127597FLJ328101
XM_001127587FLJ328101
XM_925815FLJ328101
XM_001127637FLJ328101
XM_001127623FLJ328101
NM_0208231
NM_000153GALC1
NM_172388NFATC11
NM_006162NFATC11
NM_172389NFATC11
NM_172387NFATC11
NM_006661PDE10A1
NM_014600EHD31
XM_001127087FLJ439501
NM_003873NRP11
NM_178558ZNF6801
NM_198844ZPBP21
NM_199321ZPBP21
NM_001012339DNAJA51
NM_194283DNAJA51
NM_006074TRIM221
NM_005197CHES11
NM_0010854711
NM_005338HIP11
NM_017944USP471
NM_012392PEF11
XM_944991C14orf821
XM_498578C14orf821
NM_0334031
NM_007231SLC6A141
NM_004697PRPF41
NM_016480PAIP21
NM_001033112PAIP21
NM_004849ATG51
NM_198709ARSB1
NM_016052RRP151
NM_015507EGFL61
NM_004672MAP3K61
NM_001034915RBM35A1
XM_001126666LOC7306441
XM_933738LOC6465881
XM_946142SHANK31
NM_001080420SHANK31
NM_001047160NET11
NM_005863NET11
NM_018938PCDHB41
NM_001039712DEDD1
NM_032998DEDD1
NM_001039711DEDD1
NM_017697RBM35A1
NM_003831RIOK31
NM_005662VDAC31
NM_053056CCND11
NM_207338LCTL1
NM_148174AZIN11
NM_015878AZIN11
NM_005445SMC31
NM_014319LEMD31
XM_001126970LOC7282451
XM_001130724LOC7317711
NM_006924SFRS11
NM_001078166SFRS11
NM_002491NDUFB31
NM_007159SLMAP1
NM_016441CRIM11
XM_943429LOC6464841
XM_933646LOC6464841
NM_004591CCL201
NM_022750PARP121
NM_005121THRAP11
NM_001039152RGS211
NM_173658ZNF6601
NM_012464TLL11
NM_019850NGEF1
NM_006156NEDD81
NM_015344LEPROTL11
NM_005840SPRY31
NM_004270CRSP91
NM_0011008161
NM_004093EFNB21
NM_014252SLC25A151
NM_020347LZTFL11
NM_016641MIR161
NM_024496C14orf41
NM_032151PCBD21
NM_001040446MTMR121
NM_020871LRCH21
NM_134431SLCO1A21
NM_014495ANGPTL31
NM_001957EDNRA1
NM_004665VNN21
NM_078488VNN21
NM_006073TRDN1
NM_001003805ATP5S1
NM_001003803ATP5S1
NM_133646ZAK1
NM_138789PIH1D21
NM_000259MYO5A1
NM_012417PITPNC11
NM_181671PITPNC11
NM_012081ELL21
NM_177454KIAA19461
NM_001012958DISC11
NM_198460GBP61
NM_203395IYD1
NM_198124CSMD31
NM_198123CSMD31
NM_052900CSMD31
NM_152636METT5D11
NM_033127LZTR21
NM_020856TSHZ31
NM_001008495TMEM641
NM_005171ATF11
NM_153218C13orf311
NM_020200PRTFDC11
NM_018639WSB21
XM_941810LOC2840231
XM_929835LOC2840231
NM_002988CCL181
NM_014166MED41
NM_001029954ARMETL11
NM_001024647RAB3IP1
NM_022456RAB3IP1
NM_175624RAB3IP1
NM_175625RAB3IP1
NM_175623RAB3IP1
NM_138715MSR11
NM_138716MSR11
NM_000389CDKN1A1
NM_078467CDKN1A1
NM_0010988011
NM_152352C18orf191
NM_031244SIRT51
NM_0010087811
XM_936538FAT31
XM_926199FAT31
NM_006020ALKBH11
NM_014267C11orf581
XM_940960LOC6517441
XM_928125LOC6450861
NM_014881DCLRE1A1
NM_017541CRYGS1
NM_024629MLF1IP1
XM_001129439LOC7308771
XM_001127905LOC7281961
NM_001007237IGSF31
NM_001542IGSF31
NM_207012AP3M11
NM_012095AP3M11
XM_927238LOC6439881
XM_936418LOC6473471
NM_181847AMIGO21
NM_001012993C9orf1521
NM_003551NME51
NM_001033087C20orf1331
NM_080676C20orf1331
NM_130438DYRK1A1
NM_101395DYRK1A1
NM_130437DYRK1A1
XM_938665USP6NL1
NM_001080491USP6NL1
XM_927409USP6NL1
XM_943800USP6NL1
NM_139278LGI31
NM_003932ST131
NM_033121ANKRD13A1
NM_007325GRIA31
NM_000828GRIA31
NM_145178ATOH71
NM_003725HSD17B61
NM_023930KCTD141
NM_001008701LPHN11
NM_014921LPHN11
NM_003356UCP31
NM_016089ZNF5891
NM_145659IL271
NM_032352BRMS1L1
XM_001130700LOC7295801
XM_001126751LOC7306721
NM_152221CSNK1E1
NM_001894CSNK1E1
NM_005277GPM6A1
NM_201592GPM6A1
NM_201591GPM6A1
NM_181744OPN51
NM_001030051OPN51
NM_000733CD3E1
NM_138691TMC11
NM_018293ZNF6541
XM_001126706ZNF6541
NM_172193KLHDC11
NM_022776OSBPL111
NM_003202TCF71
NM_201632TCF71
NM_213648TCF71
NM_201634TCF71
NM_017526LEPROT1
NM_032758PHF5A1
NM_004330BNIP21
NM_022445TPK11
NM_001042482TPK11
NM_032467ASPH1
NM_020164ASPH1
NM_002417MKI671
NM_001080498EMR41
NM_001031717CRELD11
NM_172240WDR51B1
NM_001015877PHF61
NM_145055C18orf251
NM_001008239C18orf251
NM_148954PSMB91
NM_002800PSMB91
NM_017438SETD41
NM_0011128001
NM_021097SLC8A11
NM_0011128011
NM_0011128021
NM_001018100Gcom11
NM_152451Gcom11
NM_018400SCN3B1
NM_001040151SCN3B1
NM_017850C1orf1091
NM_021198CTDSP11
NM_001876CPT1A1
NM_014421DKK21
NM_018351FGD61
NM_030621DICER11
NM_177438DICER11
NM_003704C4orf81
NM_033117RBM181
NM_130391PTPRD1
NM_130393PTPRD1
NM_130392PTPRD1
NM_002839PTPRD1
NM_001040712PTPRD1
NM_032382COG81
NM_013399C16orf51
NM_003946NOL31
NM_001569IRAK11
NM_001025243IRAK11
NM_001025242IRAK11
NM_006486FBLN11
NM_054033FKBP1B1
NM_004116FKBP1B1
NM_003165STXBP11
NM_001032221STXBP11
NM_020448NPAL31
NM_0010982701
NM_002409MGAT31
NM_0011004271
NM_021159RAP1GDS11
NM_0011004281
NM_0011004291
NM_0011004261
NM_0011004301
XM_001131308LOC7309611
NM_001017395TMCC11
NM_015008TMCC11
NM_022493NARFL1
NM_015488PNKD1
NM_022572PNKD1
NM_032726PLCD41
NM_017660GATAD2A1
NM_014911AAK11
NM_144498OSBPL21
NM_014835OSBPL21
NM_152414BHLHB51
NM_152219GJC11
XM_001127362KIAA05741
NM_006016CD1641
NM_001039693FLJ379531
NM_014313TMEM50A1
NM_004302ACVR1B1
NM_001551IGBP11
NM_018116MSTO11
XM_001128287LOC7310591
NM_144582TEX2611
NM_032233SETD31
NM_004767GPR37L11
NM_003427ZNF761
NM_017594DIRAS21
NM_213568SLC39A31
NM_0010136621
NM_005233EPHA31
NM_001031617COX191
NM_018146RNMTL11
NM_194286KIAA18531
NM_016577RAB6B1
NM_003713PPAP2B1
NM_177414PPAP2B1
NM_078628MSL3L11
NM_000252MTM11
NM_131916PPIL31
NM_130906PPIL31
NM_032472PPIL31
NM_138723BCL2L141
NM_030766BCL2L141
NM_138722BCL2L141
XM_096733C14orf721
XM_944937C14orf721
NM_006955ZNF33B1
NM_005030PLK11
NM_013392NRBP11
NM_007078LDB31
NM_001080114LDB31
NM_020792AADACL11
NM_024854FLJ220281
NM_006624ZMYND111
XM_001132119LOC2574071
XM_001129456LOC2574071
NM_005370RAB8A1
NM_032373PCGF51
NM_033069C6orf1141
NM_001031739ASB91
NM_019616F71
NM_000131F71
NM_018943TUBA81
NM_000875IGF1R1
NM_001427EN21
NM_000722CACNA2D11
NM_005870SAP181
NM_024770METTL81
NM_0011003981
NM_015085GARNL41
NM_021057IFNA71
NM_0207091
NM_198057TSC22D31
NM_001015881TSC22D31
NM_004089TSC22D31
NM_182903KIF91
NM_006037HDAC41
NM_000761CYP1A21
NM_004979KCND11
NM_000457HNF4A1
NM_178849HNF4A1
NM_005400PRKCE1
NM_001295CCR11
NM_016536ZNF5711
NM_153051MTMR31
NM_021090MTMR31
NM_153050MTMR31
NM_153244C10orf1111
XM_944416C17orf511
XM_378661C17orf511
NM_033036GAL3ST31
NM_014711CP1101
XM_001132013ANKH1
NM_054027ANKH1
NM_005631SMO1
NM_017888FLJ205811
NM_0059211
NM_006065SIRPB11
NM_001083910SIRPB11
NM_004779CNOT81
XM_001125845LOC7303911
XM_001127758LOC7285551
NM_134470IL1RAP1
NM_183238ZNF6051
XM_001127308FLJ376381
NM_014405CACNG41
NM_016315GULP11
NM_024090ELOVL61
NM_018252C1orf751
NM_145733SEPT31
NM_019106SEPT31
NM_001009993LOC1300741
NM_018403DCP1A1
NM_031366COL4A31
NM_000091COL4A31
NM_031365COL4A31
NM_031362COL4A31
NM_001077263TMPRSS131
NM_152418WDR21C1
NM_002228JUN1
NM_001003652SMAD21
NM_005901SMAD21
NM_015101GLT25D21
NM_020996FGF61
NM_015983UBE2D41
XM_001131309LOC7310991
XM_001127462LOC7280891
NM_080685PTPN131
NM_080683PTPN131
NM_006264PTPN131
NM_080684PTPN131
NM_0010993341
NM_005324H3F3B1
NM_173065IL28RA1
NM_173064IL28RA1
NM_170743IL28RA1
NM_012288TRAM21
NM_003590CUL31
NM_015076CDC2L61
NM_014723SNPH1
NM_003162STRN1
NM_020429SMURF11
NM_181349SMURF11
NM_001707BCL7B1
NM_003137SRPK11
NM_0010997771
NM_207102FBXW121
NM_000634IL8RA1
NM_016083CNR11
NM_033181CNR11
NM_001008390CGGBP11
NM_003663CGGBP11
NM_002657PLAGL21
NM_024969FAM130A21
NM_015655ZNF3371
NM_006043HS3ST21
NM_018339RFK1
NM_006064RRAGB1
NM_016656RRAGB1
NM_033389SSH21
NM_006785MALT11
NM_173844MALT11
NM_001040152PEG101
NM_015068PEG101
NM_014553TFCP2L11
NM_018361AGPAT51
NM_0150381
NM_024627C22orf291
XM_932949RGNEF1
NM_022845CBFB1
NM_001755CBFB1
NM_020927KIAA15761
NM_020909EPB41L51
NM_001969EIF51
NM_183004EIF51
NM_005297MCHR11
NM_003203C2orf31
NM_032408BAZ1B1
NM_012409PRND1
NM_173829P18SRP1
NM_003603SORBS21
NM_021069SORBS21
NM_001004342TRIM671
NM_005692ABCF21
NM_005607PTK21
NM_153831PTK21
XM_001132771FAM116A1
NM_152678FAM116A1
NM_148170CTSC1
NM_174896C1orf1621
NM_052907TMEM132B1
NM_0011045441
NM_0011045451
NM_017938FAM70A1
NM_014243ADAMTS31
XM_938433C20orf1231
XM_496476C20orf1231
NM_000237LPL1
NM_015455CNOT61
XM_942964LOC2864111
XM_932619LOC2864111
NM_001031684SFRS71
NM_018921PCDHGA91
NM_018923PCDHGB21
NM_018929PCDHGC51
NM_002588PCDHGC31
NM_018917PCDHGA41
NM_018918PCDHGA51
NM_032088PCDHGA81
NM_018915PCDHGA21
NM_018922PCDHGB11
NM_003736PCDHGB41
NM_018927PCDHGB71
NM_018924PCDHGB31
NM_018914PCDHGA111
NM_018920PCDHGA71
NM_018913PCDHGA101
NM_018916PCDHGA31
NM_018926PCDHGB61
NM_003735PCDHGA121
NM_032403PCDHGC31
NM_032092PCDHGA111
NM_018912PCDHGA11
NM_018919PCDHGA61
NM_018925PCDHGB51
NM_018928PCDHGC41
NM_016129COPS41
NM_175039ST6GALNAC41
NM_175040ST6GALNAC41
XM_933796SLC45A41
NM_153825SLA/LP1
NM_004984KIF5A1
NM_033331CDC14B1
NM_003671CDC14B1
NM_001077181CDC14B1
NM_012399PITPNB1
NM_003458BSN1
NM_023947CHID11
NM_001003683PDE1A1
NM_003079SMARCE11
NM_001040153SLAIN11
NM_144595SLAIN11
XM_001126392LOC7279091
XM_001126407LOC7279091
XM_001126378LOC7279091
XM_001126877LOC7280471
XM_001126928LOC7280471
XM_001126912LOC7280471
XM_926998LOC6436991
XM_001126904LOC7280471
XM_001127034LOC7280801
XM_001127051LOC7280801
XM_001127002LOC7280801
XM_001127022LOC7280801
XM_930496LOC6457521
XM_370876LOC6536431
NM_018652GOLGA1
XM_496076LOC6536411
NM_001038640GOLGA61
XM_928167LOC6451371
NM_001012423GOLGA8E1
NM_001012452FLJ326791
NM_001012420GOLGA8G1
NM_170665ATP2A21
NM_025196GRPEL11
NM_170723CDY11
NM_001003894CDY1B1
NM_005530IDH3A1
NM_194298SLC16A91
NM_144571CNOT6L1
NM_0011001641
NM_0011001661
NM_014721PHACTR21
NM_0011001651
NM_207325DPY19L31
NM_030790ITFG11
NM_019117KLHL41
NM_012072CD931
NM_018184ARL8B1
NM_002223ITPR21
NM_013372GREM11
NM_002163IRF81
NM_147175HS6ST21
NM_001077188HS6ST21
NM_004488GP51
NM_024570RNASEH2B1
NM_012420IFIT51
NM_001008539SLC7A21
NM_003046SLC7A21
NM_178585WDFY31
NM_014991WDFY31
NM_018983NOLA11
NM_032993NOLA11
NM_0010992211
NM_018404CENTA21
NM_033428C9orf1231
NM_002737PRKCA1
NM_080821C20orf1081
NM_031890CECR61
NM_022173TIA11
NM_022037TIA11
NM_024928OBFC11
NM_024541C10orf761
NM_0011051931
NM_0011051951
NM_0011051941
NM_152698FLJ383771
NM_052897MBD61
NM_022843PCDH201
NM_007315STAT11
NM_000621HTR2A1
XM_001127447LOC7284311
XM_001132105LOC7321781
NM_017617NOTCH11
NM_003104SORD1
NM_182492LRP5L1
NM_014584ERO1L1
NM_033132ZIC51
NM_0011105141
NM_000545TCF11
NM_003620PPM1D1
NM_175913JPH21
NM_001042432CLN31
NM_000086CLN31
XM_932285LOC6446521
XM_930805LOC6424261
NM_207316UNQ8461
NM_005669REEP51
NM_006250PRH11
NM_003417ZNF2641
NM_006569CGREF11
NM_139283PPTC71
NM_003074SMARCC11
NM_032557USP381
NM_001018058TFEC1
NM_012252TFEC1
NM_005417SRC1
NM_198291SRC1
NM_025125C10orf571
NM_032268ZNRF11
NM_130459TOR2A1
NM_013374PDCD6IP1
NM_001033113ENTPD81
NM_198585ENTPD81
NM_030877CTNNBL11
NM_006923SDF21
NM_080546SLC44A11
NM_001012427FOXP41
NM_138457FOXP41
NM_001012426FOXP41
NM_024699ZFAND11
NM_018509LRRC591
NM_004048B2M1
NM_001042590C9orf1271
NM_001042589C9orf1271
NM_175768GRIK21
NM_021956GRIK21
NM_152515CKAP2L1
NM_014747RIMS31
NM_145039MGC163851
NM_001011708GTPBP91
NM_013341GTPBP91
NM_032174TOMM40L1
NM_020526EPHA81
NM_003051SLC16A11
XM_940318FLJ404111
NM_001080504FLJ404111
NM_198562C3orf621
NM_198256E2F61
NM_001010971SAMD131
NM_002664PLEK1
NM_139008HFE1
NM_139003HFE1
NM_139010HFE1
NM_139011HFE1
NM_139009HFE1
NM_000410HFE1
NM_139004HFE1
NM_139007HFE1
NM_139006HFE1
NM_001012446C9orf1281
NM_030581WDR591
NM_024037C1orf1351
NM_002451MTAP1
NM_207380FLJ433391
NM_001040613TMEM701
XM_943975FLJ390801
XM_499117FLJ390801
NM_004382CRHR11
NM_002225IVD1
XM_928464LOC1465171
NM_006052DSCR31
NM_000382ALDH3A21
NM_001031806ALDH3A21
NM_006203PDE4D1
NM_0011046311
NM_002446MAP3K101
NM_020702KIAA11611
NM_203327SLC23A21
NM_005116SLC23A21
NM_001039127ZNF7181
NM_014012REM11
NM_023076C16orf281
NM_173214NFAT51
NM_006599NFAT51
NM_138714NFAT51
NM_0011131781
NM_138713NFAT51
NM_152511DUSP181
NM_001025356TMEM16F1
NM_182947GEFT1
NM_0011112701
NM_003184TAF21
NM_032569N-PAC1
NM_002198IRF11
NM_004827ABCG21
NM_152388ALS2CR41
NM_001044385ALS2CR41
NM_0010996661
NM_006096NDRG11
NM_207366FLJ440601
NM_0011096891
NM_021061ZNF2501
NM_001809CENPA1
NM_001042426CENPA1
NM_016929CLIC51
NM_004087DLG11
NM_0010984241
NM_0011055431
NM_006303JTV11
NM_001001709FLJ455371
NM_148903GREB11
NM_023926ZSCAN181
NM_014805EPM2AIP11
NM_005670EPM2A1
NM_033427CTTNBP21
NM_031886KCNA71
NM_1827627A51
NM_006912RIT11
NM_001080494C1orf341
XM_934658C1orf341
XM_945965C1orf341
XM_942427C1orf341
XM_930328C1orf341
XM_945959C1orf341
NM_001083112GPD21
NM_000408GPD21
NM_001082480ZNF6231
NM_014789ZNF6231
NM_001962EFNA51
NM_005918MDH21
NM_018319TDP11
NM_001008744TDP11
NM_014868RNF101
NM_001043318C14orf431
NM_194278C14orf431
NM_002820PTHLH1
NM_198964PTHLH1
NM_130809PRRC11
NM_003706PLA2G4C1
NM_176786IL9R1
NM_002186IL9R1
NM_004985KRAS1
NM_033360KRAS1
NM_007030TPPP1
NM_207585IFNAR21
NM_020919ALS21
XM_939663KIAA15531
NM_001080450KIAA15531
NM_016520C9orf781
NM_207497FLJ437521
NM_0209111
NM_207333ZNF3201
NM_015984UCHL51
NM_006287TFPI1
NM_003890FCGBP1
XM_001131379FCGBP1
NM_007086WDHD11
NM_001008396WDHD11
NM_173084TRIM591
NM_005895GOLGA31
NM_001034838KCNIP11
NM_001034837KCNIP11
NM_014592KCNIP11
NM_017563IL17RD1
NM_001080973IL17RD1
NM_001040875GDAP11
NM_018972GDAP11
NM_007022CYB561D21
NM_014957DENND31
NM_0153511
NM_138769RHOT21
NM_032953MLXIPL1
NM_032954MLXIPL1
NM_032951MLXIPL1
NM_032952MLXIPL1
NM_0011097541
NM_002837PTPRB1
NM_001013663LOC3913561
NM_0247761
NM_133337FER1L31
NM_013451FER1L31
XM_944080LOC6501931
XM_932038LOC6441921
NM_015329KIAA08921
NM_144770RBM111
NM_007331WHSC11
NM_020207C9orf1021
NM_022733SMAP1L1
NM_001010887ASAH3L1
NM_175861TMTC11
NM_016308CMPK1
NM_004495NRG11
XM_001128484LOC4412591
XM_001128555LOC7303231
XM_936833LOC6441961
XM_927389LOC6441961
NM_002971SATB11
NM_030660ATXN31
NM_004993ATXN31
NM_000663ABAT1
NM_020686ABAT1
NM_181523PIK3R11
NM_181504PIK3R11
NM_181524PIK3R11
NM_000053ATP7B1
NM_001005918ATP7B1
NM_016025METTL91
NM_001077180METTL91
XM_942952FLJ462841
XM_499123FLJ462841
NM_207395ZNF324B1
NM_001035511SDHC1
NM_002677PMP21
NM_177551GPR109A1
XM_001134375GPR109B1
NM_006018GPR109B1
NM_001006657WDR351
NM_020779WDR351
NM_003379VIL21
NM_0011110771
NM_002494NDUFC11
NM_013412RABL2A1
NM_007081RABL2B1
NM_001003789RABL2B1
NM_138738FCRL21
NM_030764FCRL21
NM_133265AMOT1
NM_006537USP31
XM_944271USP451
XM_939661USP451
XM_944273USP451
XM_944255USP451
XM_931094USP451
XM_931124USP451
XM_931115USP451
NM_001080481USP451
NM_015090NFASC1
NM_001881CREM1
NM_017634KCTD91
NM_005842SPRY21
NM_017778WHSC1L11
NM_0011098781
NM_016954TBX221
NM_0011098791
NM_001083591CUGBP21
NM_001025077CUGBP21
NM_006561CUGBP21
NM_001025076CUGBP21
NM_004109FDX11
NM_018325C9orf721
NM_018225SMU11
NM_032866CGNL11
NM_000623BDKRB21
NM_006252PRKAA21
NM_001042517DIAPH31
NM_002666PLIN1
NM_020386HRASLS1
XM_001129672LOC7285561
XM_001133737LOC7317451
NM_053064GNG21
XM_936868C10orf1361
XM_926383C10orf1361
NM_014157CCDC1131
NM_023073FLJ132311
NM_0011045461
NM_004962GDF101
NM_006063KBTBD101
NM_203329CD591
NM_203331CD591
NM_203330CD591
NM_000611CD591
NM_007212RNF21
NM_015879ST8SIA31
NM_0146921
NM_017637BNC21
NM_000358TGFBI1
NM_006085BPNT11
NM_152332MTAC2D11
NM_006654FRS21
NM_001042555FRS21
NM_020954KIAA16181
NM_152605ZNF7811
NM_203463LASS61
NM_014613UBXD81
NM_177422EIF2C31
NM_024852EIF2C31
NM_016142HSD17B121
NM_145698ACBD51
NM_001042473ACBD51
NM_003112SP41
NM_182757IBRDC21
NM_018373SYNJ2BP1
NM_178313SPTBN11
NM_005904SMAD71
NM_0010937551
NM_0010937561
NM_024941FLJ136111
NM_002188IL131
NM_012338TSPAN121
NM_178571MGC510251
NM_0010996421
NM_018348FLJ111711
XM_001134277LOC2213621
NM_006257PRKCQ1
NM_016410CHMP51
NM_001037533GON4L1
NM_015514NGDN1
NM_001025266LOC2853821
NM_000212ITGB31
NM_001031804MAF1
NM_014965TRAK11
NM_002063GLRA21
NM_015107PHF81
XM_001128504LOC7310691
NM_178582HM131
NM_001232CASQ21
NM_001037165FOXK11
NM_052847GNG71
NM_018211RAVER21
XM_931676LOC6435991
XM_943286LOC6483541
NM_001037325CCDC461
NM_145036CCDC461
NM_052818CG0181
NM_001079691CG0181
NM_0011013871
NM_015385SORBS11
NM_001034954SORBS11
NM_001034957SORBS11
NM_001034955SORBS11
NM_001034956SORBS11
NM_006434SORBS11
NM_024991SORBS11
XM_942240LOC6505571
NM_138328RHBDL31
NM_133460ZNF4181
NM_133264WIPF21
NM_0011026581
NM_033133CNP1
NM_173576MKX1
NM_001029874REP151
NM_004992MECP21
NM_053055THEM41
NM_001026213CYP11B11
NM_000497CYP11B11
NM_203305FAM102A1
NM_001035254FAM102A1
NM_176877INADL1
NM_000702ATP1A21
NM_153764KCNJ11
NM_153766KCNJ11
NM_000220KCNJ11
NM_153765KCNJ11
NM_153767KCNJ11
NM_0011013721
NM_0011031471
NM_0011031481
NM_0011031461
NM_015575TNRC151
NM_004594SLC9A51
NM_001033047NPNT1
NM_016531KLF31
NM_015621CCDC691
NM_025107MYCT11
NM_001037954DIXDC11
NM_033425DIXDC11
NM_002628PFN21
NM_053024PFN21
NM_005160ADRBK21
NM_207115ZNF5801
NM_016202ZNF5801
NM_001080398KIAA03681
XM_001131778KIAA03681
NM_016099GOLGA71
NM_001002296GOLGA71
NM_017752TBC1D8B1
NM_001852COL9A21
NM_003359UGDH1
NM_001001938C9orf471
NM_015485RWDD31
NM_144684ZNF4801
NM_014937INPP5F1
NM_005020PDE1C1
NM_014341MTCH11
NM_001942DSG11
NM_000266NDP1
NM_015289VPS391
NM_004091E2F21
NM_006726LRBA1
NM_006814PSMF11
NM_178578PSMF11
NM_015517MIZF1
NM_198971MIZF1
NM_032389ZNF2891
NM_002252KCNS31
NM_000133F91
NM_002214ITGB81
NM_0010981991
NM_005279GPR11
NM_153184CADM21
NM_013236ATXN101
NM_001042697ZSWIM71
NM_006272S100B1
NM_207467FLJ355301
NM_004294MTRF11
NM_015192PLCB11
NM_182734PLCB11
NM_002959SORT11
XM_001129778LOC7307851
XM_001134206LOC7299871
NM_021255PELI21
NM_015215CAMTA11
NM_004930CAPZB1
NM_012278ITGB1BP21
NM_145010C10orf631
NM_006435IFITM21
NM_016481C9orf1561
NM_001329CTBP21
NM_0010839141
NM_022802CTBP21
NM_0178921
NM_022844MYH111
NM_002474MYH111
NM_001040114MYH111
NM_001040113MYH111
NM_006931SLC2A31
NM_020935USP371
NM_001905CTPS1
NM_130440PTPRF1
NM_002840PTPRF1
NM_015338ASXL11
NM_005906MAK1
NM_004818DDX231
NM_003822NR5A21
NM_205860NR5A21
NM_014862ARNT21
NM_153226TMEM201
NM_003211TDG1
NM_002119HLA-DOA1
NM_014220TM4SF11
NM_001033551TOM1L21
NM_001082968TOM1L21
NM_018243SEPT111
NM_020424LYRM11
NM_003747TNKS1
NM_001025079CD471
NM_001777CD471
NM_198793CD471
NM_020845PITPNM21
NM_003789TRADD1
NM_153210USP431
NM_015554GLCE1
NM_001030272ARNTL1
NM_001178ARNTL1
NM_001030273ARNTL1
NM_025194ITPKC1
NM_005544IRS11
NM_015336ZDHHC171
NM_003426ZNF741
NM_006330LYPLA11
NM_1736011
NM_0010996501
NM_002398MEIS11
NM_001003656PPP2R2D1
NM_018461PPP2R2D1
NM_015397WDR40A1
NM_000337SGCD1
NM_004067CHN21
NM_001039936CHN21
NM_001732BTN1A11
NM_032440LCOR1
NM_006055LANCL11
NM_006165NFRKB1
NM_006393NEBL1
NM_145251STYX1
XM_001125680LOC7304321
XM_001125705LOC7304321
NM_015534ZZZ31
NM_001039697SNAPC31
NM_012413QPCT1
NM_182898CREB51
NM_004904CREB51
NM_001011666CREB51
NM_182899CREB51
NM_002844PTPRK1
NM_032193RNASEH2C1
NM_003135SRP191
NM_018202TMEM571
NM_030899ZNF3231
NM_145909ZNF3231
NM_003296CRISP21
NM_000686AGTR21
NM_153035C1orf831
NM_018434RNF1301
NM_000185SERPIND11
NM_015030FRYL1
NM_018367PHCA1
NM_002829PTPN31
NM_015282CLASP11
NM_022087GALNT111
NM_007006NUDT211
NM_133468BMPER1
NM_144978FLJ327451
NM_0010986721
NM_007144PCGF21
XM_001125875LOC7278181
NM_033224PURB1
NM_173573C11orf351
NM_176823S100A7A1
NM_0011112831
NM_000618IGF11
NM_0011112841
NM_006915RP21
NM_000351STS1
XM_926521LOC6531371
XM_928267LOC6532701
NM_078483SLC36A11
NM_207168ENSA1
NM_001166BIRC21
NM_005014OMD1
NM_000721CACNA1E1
NM_001015508PURG1
NM_022787NMNAT11
NM_033437PDE5A1
NM_001083PDE5A1
NM_033430PDE5A1
NM_024817THSD41
NM_001037SCN1B1
NM_021245MYOZ11
NM_002607PDGFA1
NM_033023PDGFA1
NM_020859SHROOM31
NM_153832GPR1611
NM_012214MGAT4A1
NM_000235LIPA1
NM_033220TRIM141
NM_181354OXR11
NM_001077511TCF191
NM_007109TCF191
NM_017825ADPRHL21
XM_942780SYNPO21
NM_000310PPT11
XM_001127763LOC7308201
XM_001127798LOC7283811
NM_030759NRBF21
NM_006040HS3ST41
XM_001132212HS3ST41
NM_014588VSX11
NM_001032280TFAP2A1
NM_003220TFAP2A1
NM_001042425TFAP2A1
NM_0011126631
NM_006629ZNF2711
NM_019098CNGB31
NM_018263ASXL21
NM_024742ARMC51
NM_173591C12orf641
NM_004573PLCB21
NM_018122DARS21
NM_145321OSBPL31
NM_145320OSBPL31
NM_145322OSBPL31
NM_015550OSBPL31
NM_023110FGFR11
NM_023106FGFR11
NM_015850FGFR11
NM_023111FGFR11
NM_023105FGFR11
NM_015651PHF191
XM_941807NHSL11
XM_496826NHSL11
NM_005409CXCL111
NM_001293CLNS1A1
NM_000428LTBP21
NM_152495CNIH31
NM_014315KLHDC21
NM_080820DTD11
NM_175569XG1
NM_000838GRM11
NM_032457PCDH71
NM_001530HIF1A1
NM_181054HIF1A1
NM_017664ANKRD101
NM_012465TLL21
NM_014646LPIN21
NM_004402DFFB1
NM_033034TRIM51
NM_003468FZD51
NM_030637DDHD11
NM_133493CD1091
NM_006565CTCF1
NM_013256ZNF1801
NM_020772NUFIP21
NM_000909NPY1R1
NM_032147USP441
NM_001042403USP441
NM_198461LONRF21
NM_019012PLEKHA51
NM_000926PGR1
NM_021813BACH21
NM_152772TCP11L21
NM_017882CLN61
NM_014899RHOBTB31
NM_017848FAM120C1
NM_206909PSD31
NM_015310PSD31
NM_014388C1orf1071
NM_001106ACVR2B1
NM_032780TMEM251
NM_016436PHF201
NM_006656NEU31
NM_174924PDILT1
NM_024408NOTCH21
XM_001133349NOTCH21
NM_003966SEMA5A1
NM_001798CDK21
NM_052827CDK21
NM_006807CBX11
NM_007039PTPN211
NM_003998NFKB11
NM_006773DDX181
NM_032521PARD6B1
NM_032503MCHR21
NM_001040179MCHR21
NM_002745MAPK11
NM_014145C20orf301
NM_001009923C20orf301
NM_001009924C20orf301
NM_001009925C20orf301
NM_018312SAPS31
NM_080387CLEC4D1
NM_005789PSME31
NM_176863PSME31
NM_152695ZNF4491
NM_001010853ACY1L21
NM_148571MRPL271
NM_000728CALCB1
NM_057178RFFL1
NM_001017368RFFL1
NM_138292ATM1
NM_000051ATM1
NM_005749TOB11
XM_943661LRRC381
XM_059074LRRC381
NM_001039840CHIC11
NM_032859ABHD131
NM_0146871
NM_020198CCDC471
NM_002356MARCKS1
NM_022557GH21
NM_001924GADD45A1
NM_022558GH21

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317