Predicted Off-targets for siRNA "gaaccacugcaacuuuggu" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
Warning - siRNA is specific for only the antisense (guide) strand

27 hits were found for GAACCACUGCAACUUUGGU (7 guide strand hits and 20 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_022553 VPS52 322 340 GAACCACUGCAACUUgGGg68 2 15 c false   <90%   2990
NM_024105 ALG12 2235 2253 ccACCACUGCAACUUUuGU63 3 14 ac false   <90%   2387
NM_001982 ERBB3 1783 1801 GAcCCACUGCAACUUUcug49 4 13 c false   <90%   5511
NM_001003937 TSPYL6 2693 2711 GAAaCACUGCAAuUUUGGg47 3 8   false   <90%   3080
NM_014679 CEP57 2696 2714 GAAaCACUGCAACUUUccU37 3 12 c false   <90%   3158
NM_000857 GUCY1B3 1877 1895 GAACCAaUGCAAgUUUGGU23 2 6   false   <90%   2443
NM_031954 KCTD10 1665 1683 agACCAgUGCAACUUUGGg15 4 11 bc false   <90%   4057


Hits to Sense strand





















AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_199053 FLJ12716 574 592 ACaAAAGUUGCAGUGGUUC80 1 16 bc false   <90%   4442
NM_021942 FLJ12716 574 592 ACaAAAGUUGCAGUGGUUC80 1 16 bc false   <90%   4561
NM_021110 COL14A1 3474 3492 ACCcAAGUUGCAaUGGUUC52 2 8   false   <90%   6463
NM_001013693 LDLRAD2 3821 3839 ACCAAAGUaGCAGUGGUag32 3 8 c false   <90%   4012
NM_025209 EPC1 1989 2007 guaAAAGUaGCAGUGGUUC6 4 10 bc false   <90%   2913
NM_002745 MAPK1 1625 1643 uugAAAGaUGCAGUGGUUC4 4 11 bc false   <90%   5916
XM_001128702 SGPP2 791 809 ACCAAAuUUGCAGUGGgaa2 4 9 c false   <90%   1190
NM_152386 SGPP2 974 992 ACCAAAuUUGCAGUGGgaa2 4 9 c false   <90%   1200
NM_016329 SFMBT1 1757 1775 AggAAAaUUGCAGUGGUUC2 3 12 bc false   <90%   3512
NM_001005158 SFMBT1 1876 1894 AggAAAaUUGCAGUGGUUC2 3 12 bc false   <90%   3631
NM_001005159 SFMBT1 1957 1975 AggAAAaUUGCAGUGGUUC2 3 12 bc false   <90%   3712
NM_020796 SEMA6A 1968 1986 ACCAAAaUUGCAGUGGaca2 4 9 c false   <90%   6860
XM_001132013 ANKH 6072 6090 ACCAAAaUUGCAGUGGagu2 4 9 c false   <90%   8316
NM_017573 PCSK4 352 370 cCCcAAGgUGCAGUGGUUC0 3 11 bc false   <90%   2674
NM_001080432 FTO 3224 3242 ACCAgAaUUGCAGUGGUUC-17 2 12 bc false   <90%   4294
XM_941142 FTO 3224 3242 ACCAgAaUUGCAGUGGUUC-17 2 12 bc false   <90%   4294
NM_018353 C14orf106 2637 2655 ACCAAAGaaGCAGUGGUUC-22 2 10 bc false   <90%   4584
NM_172373 ELF1 1501 1519 ACCcAAGUUcCAGUGGUUg-24 3 8 bc false   <90%   3499
NM_015265 SATB2 4615 4633 gCCAAguUUGCAGUGGUUC-31 3 12 bc false   <90%   4999
NM_153343 ENPP6 1677 1695 ACCAAAcUUGgAGUGGUUa-32 3 7 c false   <90%   3856


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1423
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_024513FYCO14
NM_001042599ERBB43
NM_005235ERBB43
NM_016009SH3GLB13
NM_002941ROBO12
NM_133631ROBO12
NM_012294RAPGEF52
NM_000332ATXN12
NM_015328KIAA08282
XM_377476MGC573462
NM_024577SH3TC22
NM_080872UNC5D2
NM_018689KIAA11992
NM_033274ADAM192
NM_015154MESDC22
NM_001083913C10orf262
NM_017787C10orf262
NM_002581PAPPA2
NM_005458GABBR22
NM_0152412
XM_001128811LOC7312102
NM_0010992202
NM_001116ADCY92
NM_0010976112
XM_936833LOC6441962
XM_927389LOC6441962
XM_937554LOC4409172
XM_496603LOC4409172
NM_025218ULBP12
NM_022151MOAP12
NM_000214JAG12
NM_014571HEYL2
NM_0011107812
NM_014157CCDC1132
NM_002953RPS6KA12
NM_001006665RPS6KA12
NM_001011668CHCHD72
NM_024300CHCHD72
NM_001011671CHCHD72
NM_001011667CHCHD72
NM_001011670CHCHD72
NM_001011669CHCHD72
NM_007350PHLDA12
NM_015553PIP3-E2
NM_004171SLC1A22
NM_001006600ERBB2IP2
NM_018695ERBB2IP2
NM_002526NT5E2
NM_002221ITPKB2
NM_0011001642
NM_0011001662
NM_014721PHACTR22
NM_0011001652
NM_001859SLC31A12
XM_001126273LOC7277732
NM_032329ING52
XM_941026ING52
NM_173638NBPF152
NM_0011026632
NM_015383NBPF142
NM_183372NBPF112
NM_006557DMRT22
NM_002613PDPK12
NM_031268PDPK12
NM_016547SDF42
NM_000587C72
NM_001080530LOC920172
NM_014231VAMP12
NM_199245VAMP12
NM_153487MDGA12
NM_001004342TRIM672
NM_173536GABRG12
NM_025136OPA32
NM_003681PDXK2
NM_006517SLC16A22
NM_002999SDC42
NM_019067GNL3L2
NM_003108SOX112
NM_001481GAS82
NM_014382ATP2C12
NM_014723SNPH2
NM_014751MTSS12
XM_001134449KBTBD92
XM_940375KBTBD92
NM_000322PRPH22
NM_006706TCERG12
NM_001040006TCERG12
NM_213596FOXN42
NM_198968DZIP12
NM_014934DZIP12
NM_013402FADS12
NM_015026MON22
NM_001002914KCTD111
NM_003494DYSF1
NM_032017STK401
NM_001001794FAM116B1
NM_182644EPHA31
NM_002241KCNJ101
NM_000278PAX21
NM_003989PAX21
NM_003990PAX21
NM_003987PAX21
NM_003988PAX21
NM_018590GALNACT-21
NM_021135RPS6KA21
NM_001006932RPS6KA21
NM_003421ZNF37A1
NM_001007094ZNF37A1
NM_004796NRXN31
NM_0011052501
NM_138970NRXN31
NM_002061GCLM1
NM_003112SP41
XM_936279LOC6421321
NM_012431SEMA3E1
NM_148169FBXO171
NM_024907FBXO171
NM_017738C9orf391
NM_003597KLF111
XM_001129527KLF111
NM_004498ONECUT11
NM_018199EXDL21
XM_001129932LOC6453321
NM_201400FAM86A1
NM_201598FAM86A1
NM_152563FAM86C1
NM_018172FAM86C1
NM_0010996531
NM_181711GRASP1
XM_936041LOC6538571
XM_930461LOC6538571
NM_207390FLJ459101
NM_080725SRXN11
NM_080539COLQ1
NM_080538COLQ1
NM_080544COLQ1
NM_005677COLQ1
NM_080541COLQ1
NM_152411ZNF7861
NM_032023RASSF41
XM_001127146IL7R1
NM_181814ABHD12B1
NM_181533ABHD12B1
NM_000809GABRA41
XM_001134423C9orf1441
NM_014655SLC25A441
NM_031911C1QTNF71
NM_007010DDX521
NM_152300DDX521
NM_201280MUTED1
NM_004147DRG11
NM_001267CHAD1
NM_0010996661
NM_001042646TRAK11
NM_020315PDXP1
NM_032979DTNA1
NM_032978DTNA1
NM_001391DTNA1
NM_032981DTNA1
NM_170711DAZAP11
NM_001038707CDC42SE11
NM_020239CDC42SE11
NM_000682ADRA2B1
XM_941807NHSL11
XM_496826NHSL11
NM_005023PGGT1B1
NM_007110TEP11
NM_025057C14orf451
NM_001039517C1orf1041
NM_017736THUMPD11
NM_182734PLCB11
NM_000492CFTR1
NM_020899ZBTB41
NM_177972TUB1
NM_003320TUB1
NM_021061ZNF2501
NM_0011096891
NM_018713SLC30A101
XM_001126965LOC7283821
NM_006306SMC1A1
NM_003101SOAT11
NM_006148LASP11
NM_152638C12orf121
NM_173602DIP2B1
XM_932289LOC6446601
XM_943717LOC6446601
NM_003203C2orf31
NM_031886KCNA71
NM_006654FRS21
NM_001042555FRS21
NM_019001XRN11
NM_001042604XRN11
NM_018662DISC11
NM_001012957DISC11
NM_022153C10orf541
XM_934649C1orf341
XM_945958C1orf341
NM_003816ADAM91
NM_001005845ADAM91
NM_003200TCF31
NM_001029858SLC35F11
NM_138340ABHD31
XM_943975FLJ390801
XM_499117FLJ390801
NM_153607LOC1532221
NM_032584ZNF3471
NM_001006656ZNF4731
NM_015428ZNF4731
NM_003618MAP4K31
NM_078476BTN2A11
NM_0011031701
NM_0011031691
NM_000397CYBB1
NM_007322RANBP31
NM_003624RANBP31
NM_007320RANBP31
XM_001133151LOC7291991
XM_001133879LOC7319181
NM_001007534C3orf561
NM_006621AHCYL11
NM_001008392CTDSPL1
NM_005808CTDSPL1
NM_002357MXD11
NM_001029875RGS7BP1
NM_014997KIAA02651
NM_016206VGLL31
NM_004566PFKFB31
NM_004795KL1
NM_001760CCND31
NM_001081573GAB31
NM_080612GAB31
NM_016081PALLD1
NM_001080115LDB31
NM_001080116LDB31
NM_014653WSCD21
NM_022818MAP1LC3B1
NM_001386DPYSL21
XM_933621LOC6436691
XM_946053LOC6436691
NM_015156RCOR11
NM_201274M-RIP1
NM_015134M-RIP1
NM_014873LPGAT11
NM_153756FNDC51
NM_019625ABCB91
NM_203444ABCB91
NM_019624ABCB91
NM_031431COG31
NM_020655JPH31
NM_015042ZNF6091
NM_020724RNF1501
NM_176877INADL1
NM_004204PIGQ1
NM_006397RNASEH2A1
NM_003948CDKL21
NM_018201TBC1D131
NM_014323PATZ11
NM_032052PATZ11
NM_032050PATZ11
NM_020717SHROOM41
NM_016424CROP1
NM_012384GMEB21
NM_002399MEIS21
NM_172316MEIS21
NM_170674MEIS21
NM_170675MEIS21
NM_170676MEIS21
NM_170677MEIS21
NM_172315MEIS21
NM_031910C1QTNF61
NM_207435FLJ401421
NM_015113ZZEF11
NM_015245ANKS1A1
NM_004077CS1
NM_198324CS1
NM_001160APAF11
NM_181868APAF11
NM_181869APAF11
NM_013229APAF11
NM_181861APAF11
NM_004863SPTLC21
NM_003722TP73L1
NM_0010988011
NM_152352C18orf191
NM_004330BNIP21
NM_000843GRM61
NM_014877HELZ1
NM_002843PTPRJ1
NM_016952CDON1
NM_001040628NCALD1
NM_001040626NCALD1
NM_001040625NCALD1
NM_032041NCALD1
NM_001040629NCALD1
NM_001040624NCALD1
NM_001040627NCALD1
NM_001040630NCALD1
NM_001185AZGP11
NM_015446AHCTF11
XM_001126456AHCTF11
NM_022770GINS31
NM_030806C1orf211
NM_002591PCK11
NM_024770METTL81
NM_018347C20orf291
NM_002623PFDN41
NM_004852ONECUT21
NM_003471KCNAB11
NM_172159KCNAB11
NM_172160KCNAB11
NM_016932SIX21
NM_020381PDSS21
NM_003387WIPF11
NM_001077269WIPF11
NM_173689CRB21
NM_032300TCHP1
NM_033229TRIM151
NM_175921LOC2856361
NM_207348SLC25A341
NM_001029885MGC103341
NM_019054FAM35A1
NM_002235KCNA61
NM_001003407ABLIM11
NM_001003408ABLIM11
NM_002313ABLIM11
NM_006720ABLIM11
NM_144571CNOT6L1
XM_001127597FLJ328101
XM_001127587FLJ328101
XM_925815FLJ328101
XM_001127637FLJ328101
XM_001127623FLJ328101
NM_017958PLEKHB21
NM_0011006231
NM_030634ZNF4361
NM_001077195ZNF4361
XM_941644LOC3998811
NM_152327AK71
NM_020177FEM1C1
NM_025219DNAJC51
NM_153718NUP621
NM_012346NUP621
NM_153719NUP621
NM_016553NUP621
NM_001037172ACPL21
NM_152282ACPL21
NM_000544TAP21
NM_130440PTPRF1
NM_002840PTPRF1
NM_015191SNF1LK21
NM_003243TGFBR31
NM_003022SH3BGRL1
NM_020914RNF2131
NM_000719CACNA1C1
XM_001132080LOC7310071
XM_928632LOC6456191
NM_203464AK3L11
NM_013410AK3L11
NM_001005353AK3L11
NM_002547OPHN11
NM_012249RHOQ1
NM_153283HYAL11
NM_153285HYAL11
NM_033159HYAL11
NM_153282HYAL11
NM_153281HYAL11
NM_007312HYAL11
NM_152510HORMAD21
NM_001776ENTPD11
NM_0010981751
NM_001012986LOC3889101
NM_133509RAD51L11
NM_005683GPR551
NM_173588IGSF221
NM_020889PHF121
NM_014455ZNF3641
XM_932309LOC6446941
XM_170840LOC2562231
NM_033331CDC14B1
NM_003671CDC14B1
NM_001077181CDC14B1
NM_015490SEC31B1
NM_057178RFFL1
NM_001017368RFFL1
NM_001039697SNAPC31
NM_001567INPPL11
NM_024099C11orf481
NM_173481C19orf211
NM_003741CHRD1
NM_001004308ZCCHC161
NM_178011LRRTM31
NM_005437NCOA41
NM_000593TAP11
NM_018228C14orf1151
NM_024730FLJ226551
NM_014309RBM91
NM_001082576RBM91
NM_001082577RBM91
NM_001031695RBM91
NM_001082578RBM91
NM_001082579RBM91
XM_001132288LOC7287161
XM_001134292LOC7322201
NM_175854PAN31
NM_001042601TTC141
NM_013339ALG61
NM_0011008141
NM_144568TMEM55B1
NM_139265EHD41
NM_018979WNK11
NM_022166XYLT11
XM_001125986LOC2838241
NM_022145CENPK1
NM_004992MECP21
NM_014613UBXD81
NM_016261TUBD11
NM_0011126631
NM_006629ZNF2711
NM_001020821MYADM1
NM_001020818MYADM1
NM_001020819MYADM1
NM_138373MYADM1
NM_001020820MYADM1
NM_001247ENTPD61
NM_017847C1orf271
NM_175876EXOC81
NM_0010099841
NM_152263TPM31
NM_016124RHD1
NM_0207331
NM_012388PLDN1
NM_002716PPP2R1B1
NM_182562FLJ397431
NM_022131CLSTN21
NM_152393KBTBD51
NM_000429MAT1A1
NM_015374UNC84B1
NM_0152581
XM_097977FAM59B1
XM_940578FAM59B1
NM_000567CRP1
NM_015564LRRTM21
NM_002015FOXO1A1
NM_016322RAB141
NM_012429SEC14L21
NM_001014809CRMP11
NM_001313CRMP11
NM_002959SORT11
NM_199246CCNG11
NM_004060CCNG11
NM_000961PTGIS1
XM_001133170LOC7288241
NM_014064C9orf321
NM_025081KIAA13051
NM_182898CREB51
NM_004904CREB51
NM_001011666CREB51
NM_182899CREB51
NM_153371LNX21
NM_000748CHRNB21
NM_0121941
NM_001043SLC6A21
NM_025083EDC31
XM_940089FLJ396391
XM_370932FLJ396391
NM_005638SYBL11
NM_015202KIAA05561
NM_020921NIN1
NM_018325C9orf721
NM_022733SMAP1L1
NM_002982CCL21
NM_014098PRDX31
NM_006793PRDX31
NM_001392DTNA1
NM_005453ZBTB221
NM_144582TEX2611
NM_003194TBP1
NM_001013406KRIT11
NM_004912KRIT11
NM_194454KRIT11
NM_194456KRIT11
NM_194455KRIT11
NM_178313SPTBN11
NM_018243SEPT111
NM_033550TP53RK1
NM_033542SYS11
NM_021925C2orf431
NM_005602CLDN111
NM_021005NR2F21
NM_021635PBOV11
XM_939663KIAA15531
NM_001080450KIAA15531
NM_003498SNN1
NM_0321731
NM_153276SLC22A61
NM_153278SLC22A61
NM_153277SLC22A61
NM_004790SLC22A61
NM_080706TRPV11
NM_018727TRPV11
NM_080704TRPV11
NM_080705TRPV11
NM_000362TIMP31
NM_001908CTSB1
NM_147781CTSB1
NM_147783CTSB1
NM_147780CTSB1
NM_147782CTSB1
NM_015983UBE2D41
NM_024877CNTD21
NM_153615Rgr1
NM_000246CIITA1
NM_006763BTG21
NM_198581ZC3H61
NM_173627FLJ352201
NM_018045BSDC11
NM_022493NARFL1
NM_001039380C10orf251
NM_134445CD99L21
NM_134446CD99L21
NM_031462CD99L21
NM_144994ANKRD231
NM_152774MGC420901
NM_000806GABRA11
NM_006885ATBF11
NM_012316KPNA61
NM_001006615WDR311
NM_145241WDR311
NM_001012361WDR311
XM_944219LOC6427811
XM_931531LOC6427811
NM_018847KLHL91
NM_001077693ECSM21
NM_002356MARCKS1
NM_015027PDXDC11
XM_001125924KIAA02511
NM_021642FCGR2A1
NM_006933SLC5A31
NM_173728ARHGEF151
XM_928464LOC1465171
NM_000574CD551
NM_001008493ENAH1
NM_018212ENAH1
NM_001795CDH51
XM_001130790KIAA18811
NM_001080400KIAA18811
NM_006135CAPZA11
NM_174911FAM84B1
NM_020844KIAA14561
NM_0010996771
NM_000424KRT51
NM_017748CCDC491
NM_002427MMP131
NM_032287LDOC1L1
NM_001035235SRA11
NM_0059211
NM_016263FZR11
XM_001127767LOC7309301
XM_001128700LOC7288831
NM_006800MSL3L11
NM_078630MSL3L11
NM_078629MSL3L11
XM_087225LOC1515071
XM_939716LOC1515071
NM_024884L2HGDH1
NM_207299PRG-31
NM_017753PRG-31
NM_015147CEP681
NM_007173PRSS231
NM_005419STAT21
NM_005725TSPAN21
NM_015247CYLD1
NM_001042412CYLD1
NM_001042355CYLD1
XM_942245FLJ327901
XM_926604FLJ327901
NM_004781VAMP31
NM_052954CYYR11
NM_033138CALD11
NM_033139CALD11
NM_004342CALD11
NM_033157CALD11
NM_033140CALD11
NM_178130TXNDC61
NM_016138COQ71
NM_198196CD961
NM_005816CD961
NM_144690ZNF5821
NM_001326CSTF31
NM_018423STYK11
NM_0010994021
NM_003858CCNK1
NM_173793LOC1289771
NM_014959CARD81
NM_015865SLC14A11
NM_024551ADIPOR21
NM_005578LPP1
NM_004464FGF51
NM_033143FGF51
NM_006761YWHAE1
NM_020699GATAD2B1
NM_002906RDX1
NM_001364DLG21
XM_001128986LOC7289801
NM_024713C15orf291
NM_194286KIAA18531
NM_152493FLJ254761
NM_033540MFN11
NM_022343C9orf191
NM_003784SERPINB71
NM_001040147SERPINB71
NM_001077196PDE11A1
NM_001077197PDE11A1
NM_016953PDE11A1
NM_032980DTNA1
NM_001390DTNA1
NM_032975DTNA1
NM_014763MRPL191
XM_942776SYNPO21
XM_936336SYNPO21
NM_001060TBXA2R1
NM_001030288SPN1
NM_003123SPN1
NM_0011055431
NM_024704C20orf231
NM_000208INSR1
NM_001079817INSR1
XM_941733LOC6471151
XM_930136LOC6471151
NM_014729TOX1
NM_203327SLC23A21
NM_005116SLC23A21
NM_000195HPS11
NM_001042552TATDN31
NM_001042553TATDN31
NM_016577RAB6B1
NM_007028TRIM311
NM_001025266LOC2853821
NM_005540INPP5B1
NM_172241CTAGE11
NM_003239TGFB31
NM_016830VAMP11
NM_005990STK101
XM_932931LOC6454851
XM_944437LOC6454851
NM_020777SORCS21
NM_030576LIMD21
NM_003131SRF1
NM_006469IVNS1ABP1
NM_030640DUSP161
NM_138635H2AFV1
NM_000327ROM11
NM_212539PRKCD1
NM_006254PRKCD1
XM_940167LOC4006521
XM_927103LOC4006521
NM_006521TFE31
NM_016052RRP151
NM_012153EHF1
NM_000785CYP27B11
NM_014553TFCP2L11
NM_004132HABP21
NM_016525UBAP11
NM_176823S100A7A1
NM_031961KRTAP9-21
NM_0319631
NM_033191KRTAP9-41
NM_004256SLC22A131
NM_002080GOT21
NM_018157RIC8B1
NM_130391PTPRD1
NM_130393PTPRD1
NM_130392PTPRD1
NM_002839PTPRD1
NM_001040712PTPRD1
NM_145053UBQLNL1
NM_001044387ZNF5571
NM_024341ZNF5571
NM_001044388ZNF5571
NM_001993F31
NM_0010996451
NM_000663ABAT1
NM_020686ABAT1
NM_012106ARL2BP1
NM_001010845LOC1238761
XM_936869LOC1238761
NM_014372RNF111
NM_019899ABCC11
NM_019862ABCC11
NM_019898ABCC11
NM_004996ABCC11
NM_019900ABCC11
NM_001017440CALN11
NM_031468CALN11
NM_052918SORCS11
NM_001013031SORCS11
NM_007136ZNF801
NM_001031730TSPAN181
NM_130783TSPAN181
XM_001133949LOC7297081
XM_001133950LOC7297081
XM_001133946LOC7297081
XM_001133945LOC7297081
XM_001133947LOC7297081
XM_001134262LOC7321651
XM_001134264LOC7321651
XM_001134261LOC7321651
XM_001134259LOC7321651
XM_001134257LOC7321651
XM_001134263LOC7321651
NM_001012993C9orf1521
NM_022817PER21
NM_001093ACACB1
NM_001520GTF3C11
NM_006505PVR1
NM_0011096621
NM_015264C22orf91
NM_001009880C22orf91
NM_005860FSTL31
NM_015144ZCCHC141
NM_000365TPI11
NM_002218ITIH41
NM_020429SMURF11
NM_181349SMURF11
NM_000337SGCD1
NM_020896OSBPL51
NM_145638OSBPL51
NM_007085FSTL11
XM_210048H2BFM1
XM_936705H2BFM1
XM_931281LOC6430721
XM_943769LOC6430721
NM_006788RALBP11
NM_001010883FAM102B1
NM_004947DOCK31
NM_080669SLC46A11
NM_000268NF21
NM_016418NF21
NM_181832NF21
NM_181828NF21
NM_181829NF21
NM_181833NF21
NM_181830NF21
NM_015063SLC8A21
NM_001003819TRIM6-TRIM341
NM_001003827TRIM341
NM_021616TRIM341
NM_130389TRIM341
NM_024080TRPM81
NM_024817THSD41
NM_033303ADRA1A1
NM_0010992721
NM_152733BTBD91
NM_0528931
NM_198447GOLT1A1
NM_017617NOTCH11
XM_939981LOC6469761
XM_929947LOC6469761
NM_000046ARSB1
NM_198993STAC21
NM_152492CCDC271
XM_001134164ETV51
NM_004454ETV51
NM_003359UGDH1
NM_024954UBTD11
NM_001077484SLC38A11
NM_030674SLC38A11
NM_014762DHCR241
XM_001127608LOC7308801
XM_001127601LOC7285101
NM_003974DOK21
NM_014901RNF441
NM_032105PPP1R12B1
NM_002481PPP1R12B1
NM_015635GAPVD11
NM_032730RTN4IP11
NM_0010982131
NM_0010982121
NM_000861HRH11
NM_0010982111
NM_018899PCDHAC21
NM_018900PCDHA11
NM_018902PCDHA111
NM_031849PCDHA61
NM_018905PCDHA21
NM_018904PCDHA131
NM_031860PCDHA101
NM_018907PCDHA41
NM_018909PCDHA61
NM_018910PCDHA71
NM_018911PCDHA81
NM_018906PCDHA31
NM_018903PCDHA121
NM_018898PCDHAC11
NM_031857PCDHA91
NM_031411PCDHA11
NM_018908PCDHA51
NM_018901PCDHA101
NM_001001668ZNF4701
NM_024705DHRS121
NM_138972BACE11
NM_012104BACE11
NM_138973BACE11
NM_138971BACE11
NM_020796SEMA6A1
NM_032111MRPL141
NM_000458TCF21
NM_019046ANKRD161
NM_006548IGF2BP21
NM_001007225IGF2BP21
NM_0151641
NM_0011016761
NM_014787DNAJC61
NM_173683XKR61
NM_001286CLCN61
NM_005895GOLGA31
NM_015898ZBTB7A1
NM_000761CYP1A21
NM_012435SHC21
XM_942832LOC6456021
XM_932995LOC6456021
NM_003820TNFRSF141
NM_001004720NCK21
NM_001004722NCK21
NM_003581NCK21
NM_017929PEX261
NM_031490LONP21
NM_145865ANKS4B1
NM_006011ST8SIA21
NM_001017405MAEA1
NM_005882MAEA1
XM_001129080LOC7307441
NM_001011658TRAPPC21
NM_014563TRAPPC21
NM_001001342BLOC1S21
NM_173809BLOC1S21
NM_017849TMEM1271
NM_001043318C14orf431
NM_194278C14orf431
NM_152275TTC30A1
NM_012071COMMD31
NM_152874FAS1
NM_152876FAS1
NM_152877FAS1
NM_152872FAS1
NM_152871FAS1
NM_152873FAS1
NM_000043FAS1
NM_152875FAS1
NM_014832TBC1D41
NM_020194C2orf331
NM_031307PUS31
NM_003966SEMA5A1
NM_005360MAF1
NM_001031804MAF1
NM_001005212OR9Q11
XM_001126406LOC7279221
NM_001040450FAM63B1
NM_001040453FAM63B1
NM_018993RIN21
NM_000069CACNA1S1
NM_015020PHLPPL1
NM_001001343MGC271211
NM_016622MRPL351
NM_003004SECTM11
NM_078469BCCIP1
NM_181472CMTM71
NM_138410CMTM71
NM_016340RAPGEF61
NM_001037160CYS11
NM_174892CD300LB1
NM_144633KCNH81
NM_001008657TCOF11
NM_020168PAK61
NM_004890SPAG71
NM_021168RAB40C1
NM_015320ARHGEF41
NM_032995ARHGEF41
NM_006842SF3B21
NM_007231SLC6A141
NM_012400PLA2G2D1
NM_017754C6orf1071
NM_032947MST1501
NM_014141CNTNAP21
NM_005207CRKL1
NM_015178RHOBTB21
NM_145273CD300LG1
NM_001557IL8RB1
NM_005663WHSC21
XM_945536LOC4009601
XM_934552LOC4009601
NM_0010985371
NM_152286PNPLA71
NM_182511CBLN21
NM_030627CPEB41
XM_944029LOC6479791
NM_015313ARHGEF121
NM_153253SIPA11
NM_006747SIPA11
NM_138415PHF21B1
NM_014337PPIL21
NM_145654RDM11
NM_018969GPR1731
NM_153051MTMR31
NM_021090MTMR31
NM_153050MTMR31
NM_052869TTYH21
NM_032646TTYH21
NM_001081491NXF11
NM_152744SDK11
NM_015409EP4001
NM_1735951
NM_003337UBE2B1
NM_001649SHROOM21
XM_001130012LOC7315471
XM_001129569LOC7291771
NM_0152971
NM_001024593ZMYND171
NM_018638ETNK11
XM_001125875LOC7278181
NM_016546C1RL1
NM_173065IL28RA1
XM_001132373LOC7309941
XM_001130568LOC7283921
XM_001130582LOC7283921
XM_001132379LOC7309941
NM_005969NAP1L41
NM_021033RAP2A1
NM_207122EXT21
NM_000401EXT21
NM_020133AGPAT41
NM_003141TRIM211
NM_014755SERTAD21
NM_031488L3MBTL21
NM_002025AFF21
NM_001029859KCTD211
NM_181458PAX31
NM_181460PAX31
NM_181457PAX31
NM_181459PAX31
NM_000918P4HB1
NM_016940C21orf61
NM_198681PLEKHG51
NM_020631PLEKHG51
NM_001042664PLEKHG51
NM_001042663PLEKHG51
NM_001042665PLEKHG51
NM_0011003901
NM_152558IQCE1
NM_001008407BCAP291
NM_0245621
NM_007171POMT11
NM_001077366POMT11
NM_001077365POMT11
NM_006667PGRMC11
NM_002390ADAM111
NM_006252PRKAA21
NM_006036PREPL1
NM_001042386PREPL1
NM_001042385PREPL1
NM_012479YWHAG1
NM_004434EML11
NM_001008707EML11
NM_004676PRY1
NM_001002758PRY21
NM_004248PRLHR1
NM_207497FLJ437521
NM_015267CUTL21
NM_032983CASP21
XM_001130955LOC7303471
XM_001127355LOC7283771
NM_000442PECAM11
NM_004140LLGL11
XM_938853LOC2854841
XM_376303LOC2854841
NM_078485COL9A11
NM_001851COL9A11
NM_053056CCND11
NM_032421CLIP21
NM_003388CLIP21
NM_133448TMEM132D1
NM_012334MYO101
NM_174921C4orf341
NM_004848C1orf381
NM_0011055561
NM_001039477C1orf381
NM_025248SNIP1
NM_000250MPO1
NM_005479FRAT11
NM_014871USP521
NM_014732KIAA05131
NM_017482ADD21
NM_017484ADD21
NM_001013627LOC3405271
NM_030630C17orf281
NM_174917LOC1973221
NM_004285H6PD1
NM_001029861NANOS21
NM_015090NFASC1
NM_152581MOSPD21
NM_030918SNX271
NM_171998RAB39B1
NM_130762MADCAM11
NM_130760MADCAM11
NM_001636SLC25A61
NM_153648SLC24A41
NM_153647SLC24A41
NM_153646SLC24A41
NM_006549CAMKK21
NM_153499CAMKK21
NM_153500CAMKK21
NM_172216CAMKK21
NM_172226CAMKK21
NM_022491SUDS31
NM_002209ITGAL1
NM_021045ZNF2481
NM_004402DFFB1
NM_005239ETS21
NM_003804RIPK11
NM_018449UBAP21
NM_001031738TMEM1501
NM_153342TMEM1501
NM_016008DYNC2LI11
XM_001127501LOC7284631
XM_001127515LOC7308631
NM_173800FLJ906501
NM_002847PTPRN21
NM_130843PTPRN21
NM_130842PTPRN21
NM_144649TMEM711
XM_001132101LOC7300181
XM_001129006LOC7312641
NM_080760DACH11
NM_080759DACH11
NM_004392DACH11
NM_024607PPP1R3B1
NM_198461LONRF21
NM_002483CEACAM61
NM_176814ZNF8001
NM_080653ATP6V1E21
NM_145259ACVR1C1
NM_0011110311
NM_0011110331
NM_0011110321
NM_003831RIOK31
NM_198441FLJ402961
XM_001132957LOC7292401
XM_001132952LOC7292331
XM_001132961LOC7292461
XM_001132965LOC7292501
NM_138288C14orf1471
NM_031444C22orf131
NM_001605AARS1
NM_005050ABCD41
NM_004843IL27RA1
XM_379228LOC4010931
XM_944985LOC4010931
NM_144635FAM131A1
NM_021128POLR2L1
NM_022100MRPS141
NM_014860SUPT7L1
NM_032859ABHD131
NM_002420TRPM11
NM_198511LANCL31
NM_052926PNMA51
NM_0011031511
NM_0011031501
NM_175861TMTC11
NM_000148FUT11
NM_138578BCL2L11
NM_001191BCL2L11
NM_022756C1orf1491
NM_139283PPTC71
NM_015344LEPROTL11
NM_001029955WDR21B1
NM_198273LYSMD31
NM_194314ZBTB411
NM_015141GPD1L1
NM_207318CXorf391
NM_019018FAM105A1
NM_000133F91
NM_203305FAM102A1
NM_001035254FAM102A1
NM_004612TGFBR11
NM_020868DPP101
NM_001004360DPP101
NM_015483KBTBD21
NM_014313TMEM50A1
NM_005546ITK1
NM_001806CEBPG1
NM_015282CLASP11
NM_014258SYCP21
NM_004657SDPR1
NM_024541C10orf761
NM_213605ZNF5171
NM_014604TAX1BP31
NM_031912SYT151
NM_001033604BBS91
NM_014451BBS91
NM_198428BBS91
NM_001033605BBS91
NM_004346CASP31
NM_032991CASP31
NM_152355ZNF4411
NM_020718USP311
NM_003438ZNF1371
NM_001040153SLAIN11
NM_144595SLAIN11
NM_005668ST8SIA41
NM_005142GIF1
NM_005989AKR1D11
NM_144607CYB5D11
NM_130830LRRC151
NM_184234RBM391
NM_004902RBM391
NM_020766PCDH191
NM_0011052431
NM_152649MLKL1
NM_001018050POLR3H1
NM_138338POLR3H1
NM_001018052POLR3H1
NM_004717DGKI1
XM_937045LOC6479881
NM_014286FREQ1
NM_001995ACSL11
NM_001083614EARS21
NM_022063C10orf841
NM_171827CD8A1
NM_001768CD8A1
XM_001132650LOC1494781
XM_001128950LOC1494781
XM_001129709LOC7314511
XM_001132432LOC7301031
NM_021814ELOVL51
NM_024646ZYG11B1
NM_032112MRPL431
NM_006283TACC11
NM_024103SLC25A231
NM_022369STRA61
NM_004428EFNA11
NM_182685EFNA11
NM_033170B3GALT51
NM_033173B3GALT51
NM_033171B3GALT51
NM_006057B3GALT51
NM_033172B3GALT51
NM_001949E2F31
NM_001039213CEACAM161
XM_001128645LOC7281451
XM_001133876LOC7318451
NM_005076CNTN21
NM_005553KRTAP5-91
NM_0010996461
NM_152908MATE21
NM_004391CYP8B11
XM_001125933LOC7277371
NM_201574SLC4A31
NM_005070SLC4A31
XM_941352LOC2552751
XM_171855LOC2552751
NM_017772TBC1D22B1
NM_173566C22orf301
NM_001005609EDA1
NM_001399EDA1
XM_001131537LOC7319941
XM_001130930LOC7296571
NM_032328EFCAB21
NM_175610TJP11
NM_003257TJP11
NM_002203ITGA21
NM_181846ZSCAN221
NM_015506MMACHC1
NM_003644GAS71
NM_201432GAS71
NM_201433GAS71
NM_001033930UBA521
NM_003333UBA521
NM_0011001591
NM_0321841
NM_024616C3orf521
NM_002610PDK11
NM_153335LYK51
NM_007148ZNF1791
NM_005197CHES11
NM_0010854711
NM_003968UBE1C1
NM_198195UBE1C1
XM_940069PPP1R3E1
XM_927029PPP1R3E1
NM_014897ZNF6521
NM_020457THAP111
NM_015471NSL11
NM_001042549NSL11
XM_001129972LOC7315341
XM_001132513LOC7301211
NM_017628KIAA15461
NM_016233PADI31
NM_021961TEAD11
NM_006239PPEF21
NM_006060IKZF11
NM_000585IL151
NM_172174IL151
NM_003413ZIC31
NM_032264NBPF31
NM_025074FRAS11
NM_033238PML1
NM_012262HS2ST11
NM_015675GADD45B1
NM_003099SNX11
NM_152826SNX11
NM_148955SNX11
NM_000875IGF1R1
NM_032501ACSS11
NM_001039130ALOX15B1
NM_001141ALOX15B1
NM_001039131ALOX15B1
NM_170776GPR971
NM_001042574CRTC31
NM_022769CRTC31
NM_014947FOXJ31
NM_014504RABGEF11
NM_152424FAM123B1
NM_016252BIRC61
NM_004598SPOCK11
NM_152272CHMP71
NM_020119ZC3HAV11
NM_000887ITGAX1
XM_001127869ITGAX1
NM_004063CDH171
NM_001039547GK51
NM_058180C21orf581
NM_000259MYO5A1
XM_001133431LOC7292301
NM_000648CCR21
NM_030761WNT41
NM_003189TAL11
NM_006883SHOX1
NM_018970GPR851
NM_152552SAMD31
NM_024866ADM21
NM_001014831PAK41
NM_001014835PAK41
NM_001014834PAK41
NM_005884PAK41
NM_001014832PAK41
NM_022745ATPAF11
NM_001042546ATPAF11
XM_001132988FLJ217671
XM_379820FLJ217671
NM_001079877RASA41
NM_006989RASA41
NM_001167BIRC41
NM_0010129941
NM_0011026511
NM_004859CLTC1
NM_181527NAT51
NM_181528NAT51
NM_016100NAT51
NM_014376CYFIP21
NM_001037332CYFIP21
NM_001037333CYFIP21
NM_015359SLC39A141
NM_052840BRUNOL61
NM_005063SCD1
NM_1736011
NM_0010996501
NM_002919RFX31
NM_080865GPR621
NM_006371CRTAP1
NM_013433TNPO21
NM_006348COG51
NM_181733COG51
NM_030798WBSCR161
NM_014153ZC3H7A1
NM_003043SLC6A61
NM_207412FLJ435821
NM_031844HNRPU1
NM_004501HNRPU1
NM_012318LETM11
NM_0010984981
NM_0010984971
NM_001039948RUTBC21
NM_133454RUTBC21
NM_014573TMEM971
NM_173214NFAT51
NM_006599NFAT51
NM_138714NFAT51
NM_0011131781
NM_138713NFAT51
NM_015046SETX1
NM_004213SLC28A11
NM_031900AGXT21
NM_001039589DPH21
NM_001384DPH21
NM_144604NHN11
NM_203316DPAGT11
NM_001382DPAGT11
NM_004319ASTN11
NM_018477ACTR101
NM_1827627A51
NM_0011049251
NM_018257PCMTD21
NM_007189ABCF21
NM_001004349FLJ454221
NM_004230EDG51
NM_005338HIP11
NM_052861MGC216751
NM_173537GTF2IRD21
NM_001003795GTF2IRD2B1
NM_030774OR51E21
NM_017515SLC35F21
NM_024913FLJ219861
NM_000334SCN4A1
NM_000167GK1
NM_203391GK1
NM_005374MPP21
NM_052864TIFA1
NM_001766CD1D1
NM_182831TNT1
NM_0011055731
NM_007038ADAMTS51
NM_002853RAD11
NM_133377RAD11
NM_006300ZNF2301
NM_001013659ZNF7931
NM_001029884PLEKHG11
NM_207406CCDC41
NM_173475DCUN1D31
NM_173812DPY19L21
NM_032575GLIS21
NM_018584CAMK2N11
NM_002299LCT1
NM_012315KLK91
NM_024313NOL121
NM_001080421UNC13A1
NM_017770ELOVL21
NM_004277SLC25A271
NM_000168GLI31
NM_002272KRT41
NM_031935HMCN11
NM_198275LOC1962641
NM_173807C1orf1011
NM_0146871
NM_033267IRX21
NM_025250TTYH31
NM_014898ZFP301
NM_005778RBM51
NM_032013NDRG31
NM_022477NDRG31
NM_147180PPP3R21
NM_001025109CD341
NM_001773CD341
NM_000990RPL27A1
NM_017523XAF11
NM_199139XAF11
XM_001129019SAPS21
NM_024596MCPH11
NM_003861WDR221
NM_002158FOXN21
NM_019055ROBO41
NM_014109ATAD21
NM_017991FLJ100811
NM_183075CYP2U11
NM_030647JHDM1D1
NM_001024647RAB3IP1
NM_022456RAB3IP1
NM_175624RAB3IP1
NM_175625RAB3IP1
NM_175623RAB3IP1
NM_152540SCFD21
NM_183397PXMP41
NM_007238PXMP41
NM_001083615MYO3B1
NM_138995MYO3B1
NM_023923PHACTR41
NM_001048183PHACTR41
NM_052903TUBGCP51
NM_0010998571
NM_003639IKBKG1
NM_0010998561
NM_178835LOC1524851
NM_0333901
NM_145808MTPN1
NM_001761CCNF1
NM_002103GYS11
NM_020808SIPA1L21
NM_030899ZNF3231
NM_145909ZNF3231
NM_005806OLIG21
NM_001196BID1
NM_197967BID1
NM_197966BID1
NM_144703LSM14B1
XM_001131702LOC1527421
XM_001128848LOC1527421
NM_014779TSC22D21
NM_134431SLCO1A21
NM_004484GPC31
NM_014830ZBTB391
NM_005502ABCA11
NM_004300ACP11
NM_007099ACP11
NM_004561OVOL11
XM_001129344OVOL11
NM_001007237IGSF31
NM_001542IGSF31
NM_024789TMEM1801
XM_001126207LOC6459741
NM_001012977LOC3405291
NM_001042506LOC6459741
XM_001130463LOC6459741
NM_001039840CHIC11
NM_018141MRPS101
NM_139076CCDC981
NM_014037SLC6A161
NM_003702RGS201
NM_170587RGS201
NM_002977SCN9A1
NM_001083591CUGBP21
NM_001025077CUGBP21
NM_006561CUGBP21
NM_001025076CUGBP21
NM_006221PIN11

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317