VIRsiRNAdb

SpecificityServer - An siRNA design program for determining siRNA specificity
Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

23 hits were found for AUUGGUCUGUUCACCAGCA (9 guide strand hits and 14 sense strand hits.)

Hits to Guide strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_017596

KIF21B

9210

9228

c

c

U

G

G

U

C

U

G

U

U

C

A

C

C

A

u

C

g

58

4

14

ac

false

<90%

9895

NM_023039

ANKRA2

1095

1113

c

U

U

u

G

U

C

U

G

U

U

C

A

C

C

A

G

u

u

53

4

13

c

false

<90%

2047

NM_206901

RTN2

480

498

A

U

U

G

G

U

C

U

a

U

U

C

A

C

C

A

u

C

c

11

3

8

c

false

<90%

1113

NM_206900

RTN2

1467

1485

A

U

U

G

G

U

C

U

a

U

U

C

A

C

C

A

u

C

c

11

3

8

c

false

<90%

2100

NM_005619

RTN2

1684

1702

A

U

U

G

G

U

C

U

a

U

U

C

A

C

C

A

u

C

c

11

3

8

c

false

<90%

2317

XR_017979

TMEM148

944

962

u

g

g

G

G

U

C

U

G

U

a

C

A

C

C

A

G

C

A

5

4

8

c

false

<90%

1787

XR_017879

TMEM148

944

962

u

g

g

G

G

U

C

U

G

U

a

C

A

C

C

A

G

C

A

5

4

8

c

false

<90%

1787

NM_007366

PLA2R1

3727

3745

A

U

U

G

G

a

C

U

G

U

U

C

A

C

C

A

c

a

g

5

4

10

c

false

<90%

4876

NM_001007267

PLA2R1

3727

3745

A

U

U

G

G

a

C

U

G

U

U

C

A

C

C

A

c

a

g

5

4

10

c

false

<90%

5160

Hits to Sense strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_023075

MPPE1

817

835

U

G

a

U

G

G

U

G

A

A

C

A

G

A

C

C

A

c

a

72

3

14

c

false

<90%

2806

NM_002029

FPR1

67

85

a

G

C

U

G

G

U

G

A

A

C

A

G

u

C

C

A

g

g

70

4

12

c

false

<90%

1334

XR_018408

LOC648864

592

610

a

G

C

U

G

G

U

G

A

A

C

A

G

A

u

C

c

A

U

49

3

13

c

false

<90%

1789

XR_016813

LOC389662

592

610

a

G

C

U

G

G

U

G

A

A

C

A

G

A

u

C

c

A

U

49

3

13

c

false

<90%

1789

NM_178584

SEPT10

476

494

a

G

C

U

G

G

U

G

A

A

C

A

G

A

u

C

c

A

U

49

3

13

c

false

<90%

3200

NM_144710

SEPT10

545

563

a

G

C

U

G

G

U

G

A

A

C

A

G

A

u

C

c

A

U

49

3

13

c

false

<90%

3269

NM_016097

IER3IP1

191

209

g

G

C

U

G

G

g

G

A

A

C

A

G

A

C

C

A

g

g

24

4

10

c

false

<90%

1491

NM_145753

PHLDB2

2098

2116

U

G

u

U

G

G

U

G

A

A

a

A

G

A

C

C

A

A

g

14

3

7

c

false

<90%

5491

NM_006048

UBE4B

735

753

U

G

C

U

G

G

U

G

g

A

C

A

G

A

C

C

u

c

U

13

3

8

c

false

<90%

5512

NM_004223

UBE2L6

425

443

U

G

C

U

G

G

U

G

A

A

u

A

G

A

C

C

g

A

a

10

3

10

c

false

<90%

1260

NM_198183

UBE2L6

434

452

U

G

C

U

G

G

U

G

A

A

u

A

G

A

C

C

g

A

a

10

3

10

c

false

<90%

1269

NM_005582

CD180

2198

2216

U

G

C

U

G

G

U

G

A

c

C

A

G

A

C

C

A

g

a

9

3

9

c

false

<90%

2697

NM_022336

EDAR

796

814

U

G

C

U

G

G

a

G

A

A

C

A

G

A

C

C

g

A

g

5

3

9

c

false

<90%

4234

NM_000322

PRPH2

2445

2463

c

c

C

U

G

G

U

G

A

c

C

A

G

A

C

C

A

A

g

-1

4

8

bc

false

<90%

2975

---

3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 981
View matched accessions

3 prime seed match details

Accession	Gene name	Hits to this gene
NM_003445	ZNF155	3
NM_198089	ZNF155	3
NM_024577	SH3TC2	2
NM_006315	PCGF3	2
NM_002006	FGF2	2
NM_004852	ONECUT2	2
NM_016206	VGLL3	2
NM_014573	TMEM97	2
NM_020375	C12orf5	2
NM_006885	ATBF1	2
NM_052832	SLC26A7	2
NM_014744	TBC1D5	2
NM_198461	LONRF2	2
NM_003799	RNMT	2
NM_012308	FBXL11	2
NM_173552	C3orf58	2
NM_198715	PTGER3	2
NM_001011658	TRAPPC2	2
NM_014563	TRAPPC2	2
NM_012192	FXC1	2
NM_000448	RAG1	2
NM_005160	ADRBK2	2
NM_004873	BAG5	2
NM_001015049	BAG5	2
NM_001015048	BAG5	2
NM_212471	PRKAR1A	2
NM_212472	PRKAR1A	2
NM_002734	PRKAR1A	2
NM_173569		2
NM_005909	MAP1B	2
NM_014553	TFCP2L1	2
NM_020405	PLXDC1	2
NM_173833	SCARA5	2
NM_201546	CDCP2	2
NM_153240	NPHP3	2
NM_031372	HNRPDL	2
NM_020335	VANGL2	2
NM_133367	PAQR8	2
NM_004666	VNN1	2
NM_001077657	C3orf43	2
NM_001018091	Gcom1	2
NM_173598	KSR2	2
NM_006572	GNA13	2
NM_021072	HCN1	2
NM_015172	BAT2D1	2
NM_032826	SLC35B4	2
XM_001129292	MBOAT2	2
NM_012137	DDAH1	2
NM_006444	SMC2	2
NM_001042550	SMC2	2
NM_001042551	SMC2	2
NM_004171	SLC1A2	2
NM_181714	C6orf152	2
NM_181705	LYRM7	1
NM_182703	ANKDD1A	1
XM_930224	LOC647190	1
XM_941815	LOC647190	1
NM_182488	USP12	1
NM_001025077	CUGBP2	1
NM_016124	RHD	1
NM_198401	ANKRD46	1
NM_033107	GTPBP10	1
NM_001042717	GTPBP10	1
NM_015367	BCL2L13	1
NM_006922	SCN3A	1
NM_001081677	SCN3A	1
NM_001081676	SCN3A	1
NM_012194		1
NM_207359	GADL1	1
XM_939123	LOC401497	1
XM_376822	LOC401497	1
NM_152624	DCP2	1
NM_017662	TRPM6	1
NM_182898	CREB5	1
NM_004904	CREB5	1
NM_001011666	CREB5	1
NM_182899	CREB5	1
NM_032578	MYPN	1
NM_032013	NDRG3	1
NM_022477	NDRG3	1
NM_015381	FAM19A5	1
NM_001082967	FAM19A5	1
NM_003983	SLC7A6	1
NM_001076785	SLC7A6	1
XM_375929	LOC400856	1
XM_376795	FLJ45872	1
XM_940037	FLJ45872	1
NM_000706	AVPR1A	1
NM_015036		1
NM_198269	HIPK1	1
NM_181358	HIPK1	1
NM_198268	HIPK1	1
NM_016952	CDON	1
NM_005149	TBX19	1
NM_024746	KIAA1822L	1
NM_182758	WDR72	1
NM_021620	PRDM13	1
NM_015150	RFTN1	1
XM_001126254	LOC730538	1
XM_001131842	LOC730358	1
XM_001131526	LOC729852	1
NM_012229	NT5C2	1
NM_052937	PCMTD1	1
NM_031283	TCF7L1	1
NM_030756	TCF7L2	1
NM_016467	ORMDL1	1
NM_152495	CNIH3	1
NM_138426	GLCCI1	1
NM_130438	DYRK1A	1
NM_101395	DYRK1A	1
NM_130436	DYRK1A	1
NM_001396	DYRK1A	1
NM_130437	DYRK1A	1
NM_020801	ARRDC3	1
NM_172337	OTX2	1
NM_021728	OTX2	1
XM_037557	KIAA0984	1
XM_939476	KIAA0984	1
NM_001017395	TMCC1	1
NM_015008	TMCC1	1
NM_058173	SBEM	1
NM_001089704		1
NM_015646	RAP1B	1
NM_001010942	RAP1B	1
NM_173825	RABL3	1
XM_926634	LOC653256	1
NM_183078	RNF8	1
NM_003958	RNF8	1
NM_152735	ZBTB9	1
NM_016221	DCTN4	1
NM_000430	PAFAH1B1	1
XM_001134072	PSMD12	1
NM_020871	LRCH2	1
NM_030634	ZNF436	1
NM_001077195	ZNF436	1
NM_139323	YWHAB	1
NM_003404	YWHAB	1
NM_022103	ZNF667	1
NM_052932	TMEM123	1
NM_002310	LIFR	1
NM_018445	SELS	1
NM_000786	CYP51A1	1
NM_020440	PTGFRN	1
NM_153456	HS6ST3	1
NM_005374	MPP2	1
NM_016653	ZAK	1
NM_054014	FKBP1A	1
NM_005783	TXNDC9	1
NM_145257	C1orf96	1
NM_024656	GLT25D1	1
NM_024511	C4orf15	1
NM_033198	PIGS	1
NM_144625	WDR64	1
NM_194329	RNF38	1
NM_194328	RNF38	1
NM_194330	RNF38	1
NM_022781	RNF38	1
NM_194332	RNF38	1
NM_017933	PID1	1
NM_001100818		1
NM_005038	PPID	1
NM_005482	PIGK	1
NM_005955	MTF1	1
NM_019850	NGEF	1
NM_033141	MAP3K9	1
NM_017712	PGPEP1	1
NM_001776	ENTPD1	1
NM_001098175		1
NM_173822	FAM126B	1
NM_021959	PPP1R11	1
NM_003325	HIRA	1
NM_057180	VPS29	1
NM_016226	VPS29	1
NM_005497	GJA7	1
NM_001080383	GJA7	1
NM_005100	AKAP12	1
NM_144497	AKAP12	1
NM_002480	PPP1R12A	1
NM_152520	ZNF533	1
XM_001127087	FLJ43950	1
NM_020165	RAD18	1
NM_003960	NAT8	1
NM_016347	NAT8B	1
NM_018944	C21orf45	1
NM_014637	MTFR1	1
NM_003861	WDR22	1
NM_016355	DDX47	1
NM_201224	DDX47	1
NM_022166	XYLT1	1
NM_012069	ATP1B4	1
XM_001133827	LOC731816	1
NM_021181	SLAMF7	1
NM_006016	CD164	1
NM_152380	TBX15	1
NM_001025233	CLLU1	1
NM_003763	STX16	1
NM_001001433	STX16	1
NM_019110	ZKSCAN4	1
NM_005921		1
NM_006529	GLRA3	1
NM_001042543	GLRA3	1
NM_181442	ADNP	1
NM_015339	ADNP	1
NM_015231	NUP160	1
NM_052910	SLITRK1	1
NM_003784	SERPINB7	1
NM_001040147	SERPINB7	1
NM_031917	ANGPTL6	1
NM_021045	ZNF248	1
NM_181836	TMED7	1
NM_206893	MS4A10	1
NM_001099294		1
XM_936510	KIAA1644	1
NM_001005473	PLCXD3	1
NM_138358	C19orf52	1
NM_031844	HNRPU	1
NM_004501	HNRPU	1
NM_176081	TRDMT1	1
NM_004412	TRDMT1	1
NM_176083	TRDMT1	1
NM_016441	CRIM1	1
NM_000145	FSHR	1
NM_181446	FSHR	1
XM_932840	FBF1	1
XM_946193	FBF1	1
XM_371079	FBF1	1
XM_942657	FBF1	1
NM_001523	HAS1	1
NM_003326	TNFSF4	1
NM_153218	C13orf31	1
NM_001076675	ZNF626	1
NM_005876		1
XM_001126082	LOC727890	1
XM_001130162	LOC731591	1
NM_006266	RALGDS	1
NM_001042368	RALGDS	1
NM_032453		1
NM_206926	SEPN1	1
NM_020451	SEPN1	1
NM_017831	RNF125	1
NM_003034	ST8SIA1	1
NM_032160	DSEL	1
NM_001690	ATP6V1A	1
NM_198681	PLEKHG5	1
NM_020631	PLEKHG5	1
NM_001042664	PLEKHG5	1
NM_001042663	PLEKHG5	1
NM_001042665	PLEKHG5	1
NM_018091	ELP3	1
NM_032120	DKFZP564O0523	1
NM_007167	ZMYM6	1
NM_024636	STEAP4	1
NM_203307	ZNF321	1
NM_001080391	SP100	1
NM_001085400		1
NM_015076	CDC2L6	1
NM_024312	GNPTAB	1
NM_000254	MTR	1
NM_182935	MOBP	1
NM_000599	IGFBP5	1
NM_004781	VAMP3	1
NM_153229	TMEM92	1
NM_021269	ZNF708	1
NM_001652	AQP6	1
NM_001080415	SR140	1
XM_940802	SR140	1
NM_006282	STK4	1
NM_032737	LMNB2	1
NM_152400	C4orf32	1
NM_138381	OXNAD1	1
NM_017801	CMTM6	1
NM_018425	PI4KII	1
XM_932949	RGNEF	1
NM_019022	TXNDC10	1
NM_003972	BTAF1	1
NM_018452	C6orf35	1
NM_014765	TOMM20	1
XM_001131702	LOC152742	1
XM_001128848	LOC152742	1
NM_006317	BASP1	1
NM_021783	EDA2R	1
NM_152283		1
NM_024430	PSTPIP2	1
NM_024798	SNX22	1
NM_199133	LOC134145	1
NM_020823		1
NM_002359	MAFG	1
NM_032711	MAFG	1
NM_001099652		1
NM_030924	ACSBG2	1
NM_020432	PHTF2	1
NM_182641	BPTF	1
NM_004459	BPTF	1
NM_005933	MLL	1
NM_003420	ZNF35	1
NM_001558	IL10RA	1
NM_001100164		1
NM_001100166		1
NM_014721	PHACTR2	1
NM_001100165		1
NM_001105659		1
NM_001044387	ZNF557	1
NM_024341	ZNF557	1
NM_001044388	ZNF557	1
NM_001038707	CDC42SE1	1
NM_020239	CDC42SE1	1
NM_001289	CLIC2	1
NM_004067	CHN2	1
NM_001039936	CHN2	1
XM_371655	LOC389137	1
XM_937241	LOC389137	1
NM_031905	ARMC10	1
NM_018045	BSDC1	1
NM_020177	FEM1C	1
XM_378661	C17orf51	1
XM_944416	C17orf51	1
NM_173499	SPATA8	1
NM_002040	GABPA	1
NM_001099921		1
NM_153261	TMEM188	1
NM_015313	ARHGEF12	1
NM_001102421		1
NM_001102420		1
NM_006007	ZFAND5	1
NM_001039656	MTL5	1
NM_000103	CYP19A1	1
NM_031226	CYP19A1	1
NM_018976	SLC38A2	1
NM_001083617	RB1CC1	1
NM_014781	RB1CC1	1
NM_005073	SLC15A1	1
NM_001012515	FECH	1
NM_000140	FECH	1
NM_017799	C14orf101	1
NM_177553	GAS2	1
NM_005256	GAS2	1
NM_001040285	PAPD5	1
NM_001040284	PAPD5	1
NM_032505	KBTBD8	1
NM_001455	FOXO3A	1
NM_201559	FOXO3A	1
NM_001013848	EXOC6	1
NM_019053	EXOC6	1
NM_014431	KIAA1274	1
NM_004326	BCL9	1
NM_152484	ZNF569	1
NM_172169	CAMK2G	1
NM_001222	CAMK2G	1
NM_172173	CAMK2G	1
NM_172171	CAMK2G	1
NM_172170	CAMK2G	1
NM_004975	KCNB1	1
NM_015046	SETX	1
NM_182848	CLDN10	1
NM_006984	CLDN10	1
NM_013377	PDZRN4	1
NM_016277	RAB23	1
NM_183227	RAB23	1
NM_001104647		1
NM_018155	SLC25A36	1
NM_017813	IMPAD1	1
NM_016052	RRP15	1
NM_016829	OGG1	1
NM_016827	OGG1	1
NM_016828	OGG1	1
NM_001083625	ANKRD12	1
NM_015208	ANKRD12	1
NM_152622	MIER3	1
NM_152519	FLJ23861	1
NM_020840		1
NM_021815	SLC5A7	1
NM_002709	PPP1CB	1
NM_206876	PPP1CB	1
NM_173494	CXorf41	1
NM_207171	POGZ	1
NM_015100	POGZ	1
NM_002670	PLS1	1
NM_172071	RC3H1	1
NM_012262	HS2ST1	1
NM_000397	CYBB	1
NM_015576	ERC2	1
NM_005095	ZMYM4	1
NM_003463	PTP4A1	1
NM_016252	BIRC6	1
NM_033656	BRWD1	1
NM_024539	RNF128	1
NM_194463	RNF128	1
NM_020678	LRTM1	1
NM_002202	ISL1	1
NM_001099287		1
NM_014952	BAHD1	1
NM_015326	SRGAP2	1
NM_001007176	C8orf22	1
NM_024573	C6orf211	1
NM_198966	PTHLH	1
NM_198965	PTHLH	1
NM_005453	ZBTB22	1
NM_002293	LAMC1	1
NM_001754	RUNX1	1
NM_001001890	RUNX1	1
NM_153223	CCDC100	1
NM_020734	FAM80B	1
NM_005742	PDIA6	1
NM_015153	PHF3	1
NM_001098213		1
NM_001098212		1
NM_000861	HRH1	1
NM_001098211		1
NM_194298	SLC16A9	1
NM_001447	FAT2	1
NM_001037164	ARL4A	1
NM_005738	ARL4A	1
NM_212460	ARL4A	1
NM_000961	PTGIS	1
NM_021913	AXL	1
NM_001699	AXL	1
NM_000990	RPL27A	1
NM_002015	FOXO1A	1
XM_378914	KIAA0492	1
XM_944290	KIAA0492	1
NM_145259	ACVR1C	1
NM_001111031		1
NM_001111033		1
NM_001111032		1
NM_017994	C7orf42	1
NM_020141	C1orf119	1
XM_001125727	LOC727778	1
XM_001125757	LOC727778	1
XM_001134296	LOC730118	1
NM_133450	ANKS3	1
NM_004265	FADS2	1
NM_012214	MGAT4A	1
NM_004464	FGF5	1
NM_033143	FGF5	1
NM_032486	DCTN5	1
NM_001103161		1
NM_001103160		1
NM_007085	FSTL1	1
NM_207405	FLJ46481	1
NM_001099780		1
NM_000376	VDR	1
NM_001017535	VDR	1
NM_024770	METTL8	1
NM_001001694	FLJ41993	1
NM_005776	CNIH	1
NM_203341	SEP15	1
NM_004261	SEP15	1
NM_194286	KIAA1853	1
NM_013385	PSCD4	1
NM_194271	RNF34	1
NM_025126	RNF34	1
NM_024871	MAP6D1	1
XM_942673	FLJ44379	1
XM_946212	FLJ44379	1
XM_059578	FLJ44379	1
NM_001080537	FLJ44379	1
NM_024408	NOTCH2	1
XM_001133349	NOTCH2	1
NM_000684	ADRB1	1
XM_001132119	LOC257407	1
XM_001129456	LOC257407	1
NM_017912	HERC6	1
NM_004976	KCNC1	1
NM_024646	ZYG11B	1
NM_016096	ZNF706	1
NM_001042511	ZNF706	1
NM_001042510	ZNF706	1
NM_001015887	IGSF11	1
NM_152538	IGSF11	1
NM_022482	GZF1	1
XM_943073	LOC647869	1
NM_014382	ATP2C1	1
NM_173554	C10orf107	1
NM_014655	SLC25A44	1
NM_152942	TNFRSF8	1
NM_001243	TNFRSF8	1
NM_006245	PPP2R5D	1
NM_180976	PPP2R5D	1
NM_180977	PPP2R5D	1
NM_013382	POMT2	1
NM_020703	AMIGO1	1
NM_006943	SOX12	1
XM_941162	LOC400950	1
XM_376049	LOC400950	1
NM_015651	PHF19	1
NM_015696	GPX7	1
NM_015346	ZFYVE26	1
NM_003439	ZKSCAN1	1
NM_015358	MORC3	1
NM_012215	MGEA5	1
NM_005434	MALL	1
NM_153756	FNDC5	1
NM_016605	FAM53C	1
NM_173832	ZFP41	1
NM_182517	C1orf210	1
NM_152709	STOX1	1
NM_207514	FLJ20186	1
NM_002640	SERPINB8	1
NM_198833	SERPINB8	1
NM_147162	IL11RA	1
NM_001042559	EIF4G2	1
NM_001418	EIF4G2	1
NM_030793	FBXO38	1
NM_205836	FBXO38	1
NM_019885	CYP26B1	1
NM_031896	CACNG7	1
NM_153835	GPR113	1
NM_020746	VISA	1
NM_001033930	UBA52	1
NM_003333	UBA52	1
NM_014826	CDC42BPA	1
NM_003607	CDC42BPA	1
NM_138967	SCAMP5	1
NM_022817	PER2	1
NM_006888	CALM1	1
NM_016284	CNOT1	1
NM_006981	NR4A3	1
NM_173198	NR4A3	1
NM_173200	NR4A3	1
NM_005067	SIAH2	1
XM_001129151	LOC729047	1
NM_198484	ZNF621	1
NM_001098414		1
NM_000217	KCNA1	1
NM_005831	CALCOCO2	1
NM_000575	IL1A	1
NM_012279	ZNF346	1
NM_018941	CLN8	1
NM_003410	ZFX	1
NM_024590	ARSJ	1
NM_004434	EML1	1
NM_001008707	EML1	1
NM_005026	PIK3CD	1
XM_001130189	LOC731598	1
XM_001129850	LOC729291	1
NM_002565	P2RY4	1
NM_001039591	USP9X	1
NM_001039590	USP9X	1
NM_006122	MAN2A2	1
NM_001001389	CD44	1
NM_001001390	CD44	1
NM_001001391	CD44	1
NM_001001392	CD44	1
NM_000610	CD44	1
NM_018157	RIC8B	1
NM_001012958	DISC1	1
NM_003441	ZNF141	1
NM_032268	ZNRF1	1
NM_001106	ACVR2B	1
NM_020962	NOPE	1
NM_024046	CAMKV	1
NM_182505	C9orf85	1
NM_001105529		1
NM_006095	ATP8A1	1
NM_032439	PHYHIPL	1
NM_022346	NCAPG	1
NM_016929	CLIC5	1
NM_016531	KLF3	1
NM_001003940	BMF	1
NM_001003943	BMF	1
NM_001003942	BMF	1
NM_033503	BMF	1
NM_015394	ZNF10	1
XM_931094	USP45	1
XM_931124	USP45	1
XM_931115	USP45	1
XM_944271	USP45	1
XM_939661	USP45	1
XM_944273	USP45	1
XM_944255	USP45	1
NM_001080481	USP45	1
XM_943975	FLJ39080	1
XM_499117	FLJ39080	1
NM_022130	GOLPH3	1
NM_001080436	WTIP	1
XM_939855	WTIP	1
NM_152287	ZNF276	1
NM_020809	ARHGAP20	1
NM_002765	PRPS2	1
NM_001039091	PRPS2	1
NM_000434	NEU1	1
NM_001042404	CEP170	1
NM_014812	CEP170	1
NM_001042405	CEP170	1
NM_001004317	LIN28B	1
XM_001128799	MAP3K2	1
NM_021239	RBM25	1
NM_001663	ARF6	1
XM_001130020	KIAA1147	1
XM_001130081	KIAA1147	1
NM_001080392	KIAA1147	1
NM_001656	TRIM23	1
NM_015056	RRP1B	1
NM_001010874	SRD5A2L2	1
NM_020437	ASPHD2	1
NM_001001668	ZNF470	1
NM_021994	ZNF277P	1
NM_005927	MFAP3	1
NM_003449	TRIM26	1
NM_001009899	KIAA2018	1
XM_934743	FBXO46	1
XM_946240	FBXO46	1
NM_001080469	FBXO46	1
XM_946239	FBXO46	1
NM_153689	FLJ38973	1
NM_032357	CCDC115	1
NM_000134	FABP2	1
NM_000380	XPA	1
NM_022898	BCL11B	1
NM_138576	BCL11B	1
XM_938924	LOC644092	1
XM_001130314	LOC644092	1
NM_014504	RABGEF1	1
NM_020161	DKFZp547H025	1
NM_012164	FBXW2	1
NM_207511	C9orf139	1
NM_001112800		1
NM_021097	SLC8A1	1
NM_001112801		1
NM_001112802		1
NM_018231	FLJ10815	1
NM_012295	CABIN1	1
NM_004271	LY86	1
NM_004823	KCNK6	1
NM_178470	WDR40B	1
NM_024690	MUC16	1
NM_000361	THBD	1
NM_130847	AMOTL1	1
NM_014337	PPIL2	1
NM_148176	PPIL2	1
NM_148175	PPIL2	1
NM_001303	COX10	1
NM_020959	TMEM16H	1
NM_153717	EVC	1
XM_931945	LOC643962	1
XM_943665	LOC643962	1
NM_133458	ZFP90	1
NM_199169	TMEPAI	1
NM_199170	TMEPAI	1
NM_199171	TMEPAI	1
NM_020182	TMEPAI	1
XM_001126926	LOC727934	1
XM_001133457	LOC731772	1
NM_145053	UBQLNL	1
NM_020964	KIAA1632	1
NM_032446	MEGF10	1
NM_005715	UST	1
NM_130386	COLEC12	1
NM_003617	RGS5	1
NM_022757	CCDC14	1
NM_005121	THRAP1	1
NM_014787	DNAJC6	1
NM_022154	SLC39A8	1
NM_032211	LOXL4	1
NM_002721	PPP6C	1
NM_144664	FAM76B	1
NM_018241	TMEM34	1
NM_014730	KIAA0152	1
NM_016533	NINJ2	1
NM_022756	C1orf149	1
XM_001134215	PDPR	1
NM_017990	PDPR	1
NM_003966	SEMA5A	1
NM_000576	IL1B	1
NM_001009571	CADPS2	1
NM_017954	CADPS2	1
NM_144984	C10orf72	1
NM_001160	APAF1	1
NM_181868	APAF1	1
NM_181869	APAF1	1
NM_013229	APAF1	1
NM_181861	APAF1	1
NM_018318	CCDC91	1
NM_006912	RIT1	1
NM_022149	MAGEF1	1
NM_017655	GIPC2	1
NM_018451	CENPJ	1
XM_941810	LOC284023	1
XM_929835	LOC284023	1
XM_001128037	LOC728654	1
XM_001129553	LOC731413	1
NM_152288	TMEM142C	1
NM_016231	NLK	1
NM_020673	RAB22A	1
NM_006606	RBBP9	1
NM_138771	CCDC126	1
NM_138738	FCRL2	1
NM_030764	FCRL2	1
NM_001660	ARF4	1
XM_001132763	ARF4	1
NM_001018108	SERF2	1
NM_015156	RCOR1	1
NM_152682	RWDD4A	1
NM_015101	GLT25D2	1
NM_018273	TMEM143	1
NM_178454	TMEM77	1
NM_004745	DLGAP2	1
NM_182501	MTERFD2	1
NM_001955	EDN1	1
NM_001100624		1
NM_152551	C6orf151	1
XM_001133948	LOC731855	1
NM_024945	RMI1	1
NM_052947	ALPK2	1
NM_012316	KPNA6	1
NM_000060	BTD	1
NM_147202	C9orf25	1
NM_014331	SLC7A11	1
NM_014435	ASAHL	1
NM_023929	ZBTB10	1
NM_001105539		1
XM_001133595	LOC729324	1
XM_001133813	LOC731757	1
NM_178173	CCDC36	1
NM_016233	PADI3	1
NM_015295		1
NM_014949	KIAA0907	1
NM_014634	PPM1F	1
NM_015446	AHCTF1	1
XM_001126456	AHCTF1	1
NM_198989	DLEU7	1
NM_033117	RBM18	1
NM_003637	ITGA10	1
NM_001969	EIF5	1
NM_183004	EIF5	1
NM_004462	FDFT1	1
NM_052971	LEAP2	1
NM_000252	MTM1	1
NM_001100421		1
NM_001100420		1
NM_017447	C21orf91	1
NM_000104	CYP1B1	1
NM_000499	CYP1A1	1
NM_003012	SFRP1	1
NM_004293	GDA	1
NM_017671	C20orf42	1
NM_033020	TRIM33	1
NM_015906	TRIM33	1
NM_004513	IL16	1
NM_172217	IL16	1
NM_031290	CCDC70	1
NM_152478	ZNF583	1
NM_017759	FLJ20309	1
NM_004630	SF1	1
NM_006663	PPP1R13L	1
NM_203372	ACSL3	1
NM_004457	ACSL3	1
NM_021101	CLDN1	1
NM_001017416	USP1	1
NM_001017415	USP1	1
NM_003368	USP1	1
NM_001080530	LOC92017	1
NM_001008737	LOC401052	1
NM_000141	FGFR2	1
NM_022970	FGFR2	1
NM_080669	SLC46A1	1
NM_001002251	ARL6IP4	1
NM_016638	ARL6IP4	1
NM_018694	ARL6IP4	1
NM_001002252	ARL6IP4	1
NM_006017	PROM1	1
NM_152292	RG9MTD2	1
NM_005687	FARSB	1
NM_018715	RCC2	1
NM_005036	PPARA	1
NM_001001928	PPARA	1
NM_182603	ANKRD42	1
NM_006108	SPON1	1
NM_022731	NUCKS1	1
NM_001128	AP1G1	1
NM_001030007	AP1G1	1
NM_000292	PHKA2	1
NM_017761	PNRC2	1
NM_014840	NUAK1	1
NM_152765	C8orf46	1
NM_033637	BTRC	1
NM_003939	BTRC	1
NM_004730	ETF1	1
NM_013332	HIG2	1
NM_001098786		1
NM_173602	DIP2B	1
NM_205548	UNQ9217	1
NM_030767	AKNA	1
NM_016298	FBXO40	1
NM_001941	DSC3	1
NM_024423	DSC3	1
NM_181500	CUTL1	1
NM_001913	CUTL1	1
NM_198859	PRICKLE2	1
NM_014906	PPM1E	1
NM_001018090	Gcom1	1
NM_001018102	GRINL1A	1
NM_015532	GRINL1A	1
XM_291095	LOC339970	1
XM_943391	LOC339970	1
NM_001039397	FLJ40244	1
NM_015090	NFASC	1
NM_022735	ACBD3	1
NM_013300	C12orf24	1
NM_138972	BACE1	1
NM_012104	BACE1	1
NM_138973	BACE1	1
NM_138971	BACE1	1
XM_944031	LOC644248	1
XM_932073	LOC644248	1
XM_001134423	C9orf144	1
NM_032823	C9orf3	1
NM_000189	HK2	1
NM_003690	PRKRA	1
NM_017413	APLN	1
NM_173500	TTBK2	1
NM_001003407	ABLIM1	1
NM_001003408	ABLIM1	1
NM_002313	ABLIM1	1
NM_006720	ABLIM1	1
NM_153823	GSG1	1
NM_031289	GSG1	1
NM_001080555	GSG1	1
NM_001080554	GSG1	1
NM_002149	HPCAL1	1
NM_134421	HPCAL1	1
NM_002053	GBP1	1
NM_005188	CBL	1
NM_000875	IGF1R	1
NM_018970	GPR85	1
NM_015375	RIPK5	1
NM_199462	RIPK5	1
NM_175898	C15orf37	1
NM_182832	PLAC4	1
NM_005835	SLC17A2	1
NM_194434	VAPA	1
NM_003574	VAPA	1
NM_152729	NT5DC1	1
NM_148960	CLDN19	1
NM_002553	ORC5L	1
NM_183397	PXMP4	1
NM_007238	PXMP4	1
NM_001001420	SMAD5	1
NM_001001419	SMAD5	1
NM_005903	SMAD5	1
NM_004386	NCAN	1
NM_003032	ST6GAL1	1
NM_173217	ST6GAL1	1
NM_173216	ST6GAL1	1
NM_014698	TMEM63A	1
NM_173627	FLJ35220	1
NM_020406	CD177	1
NM_001009909	LUZP2	1
NM_016184	CLEC4A	1
NM_194450	CLEC4A	1
NM_194447	CLEC4A	1
NM_194448	CLEC4A	1
NM_001001716	NFKBIB	1
NM_001085357		1
NM_181780	BTLA	1
NM_001004308	ZCCHC16	1
NM_000632	ITGAM	1
NM_030817	APOLD1	1
NM_012101	TRIM29	1
NM_016505	ZCCHC17	1
NM_012345	NUFIP1	1
NM_006546	IGF2BP1	1
NM_033505	SELI	1
NM_022901	LRRC19	1
NM_003134	SRP14	1
NM_001040152	PEG10	1
NM_015068	PEG10	1
NM_020198	CCDC47	1
NM_032047	B3GNT5	1
NM_003920	TIMELESS	1
NM_002942	ROBO2	1
NM_017848	FAM120C	1
NM_015271	TRIM2	1
NM_001039585	PTGFR	1
NM_000959	PTGFR	1
NM_145341	PDCD4	1
NM_014456	PDCD4	1
NM_001098718		1
XM_930068	LOC653809	1
XM_926086	LOC653114	1
NM_015595	SGEF	1
NM_005399	PRKAB2	1
NM_017755	NSUN2	1
NM_018945	PDE7B	1
NM_020466	LYRM2	1
NM_001742	CALCR	1
NM_183419	RNF19	1
NM_015435	RNF19	1
NM_181458	PAX3	1
NM_181460	PAX3	1
NM_181457	PAX3	1
NM_181459	PAX3	1
NM_001100400		1
XM_938665	USP6NL	1
NM_001080491	USP6NL	1
XM_927409	USP6NL	1
XM_943800	USP6NL	1
NM_032434	ZNF512	1
NM_021809	TGIF2	1
NM_015021		1
NM_194247	HNRPA3	1
NM_001304	CPD	1
NM_152309	PIK3AP1	1
NM_022373	HERPUD2	1
NM_052965	C1orf19	1
XM_945887	LOC644090	1
XM_935946	LOC641912	1
XM_931994	LOC644090	1
NM_002657	PLAGL2	1
NM_014423	AFF4	1
NM_181777	UBE2A	1
NM_181762	UBE2A	1
NM_003336	UBE2A	1
NM_000550	TYRP1	1
NM_001012339	DNAJA5	1
NM_194283	DNAJA5	1
NM_024953	C12orf30	1
NM_199454	PRDM16	1
NM_022114	PRDM16	1
NM_001077654	TNFAIP8	1
NM_014350	TNFAIP8	1
NM_004663	RAB11A	1
NM_003948	CDKL2	1
NM_001102445		1
NM_005613	RGS4	1
NM_002284	KRT86	1
NM_021161	KCNK10	1
NM_138318	KCNK10	1
NM_138317	KCNK10	1
NM_001029864	KIAA1755	1
NM_003098	SNTA1	1
NM_018265	C1orf106	1
NM_004637	RAB7A	1
NM_017943	FBXO34	1
NM_004440	EPHA7	1
NM_025015	HSPA12A	1
NM_015264	C22orf9	1
NM_001009880	C22orf9	1
NM_001248	ENTPD3	1
NM_014873	LPGAT1	1
NM_014764	DAZAP2	1
NM_015419	MXRA5	1
NM_016142	HSD17B12	1
NM_006933	SLC5A3	1
NM_033481	FBXO9	1
NM_033480	FBXO9	1
NM_012347	FBXO9	1
NM_001012427	FOXP4	1
NM_138457	FOXP4	1
NM_001012426	FOXP4	1
NM_014155	ZBTB44	1
NM_005443	PAPSS1	1
NM_006141	DYNC1LI2	1
NM_145014	HYLS1	1
NM_006996	SLC19A2	1
NM_024674	LIN28	1
NM_001086	AADAC	1
NM_002610	PDK1	1
NM_017946	FKBP14	1
NM_003505	FZD1	1
NM_017415	KLHL3	1
NM_033403		1
NM_001010891	MTX3	1
NM_016021	UBE2J1	1
NM_003292	TPR	1
NM_001039618	CREBZF	1
NM_018566	YOD1	1
NM_022719	DGCR14	1
NM_017554	PARP14	1
NM_015225	KIAA0367	1
NM_020127	TUFT1	1
NM_018475	TMEM165	1
NM_012287	CENTB2	1
NM_005749	TOB1	1
XM_930678	LOC642441	1
NM_001077637	LOC150786	1
NM_198896	RAB6A	1
NM_002869	RAB6A	1
NM_003629	PIK3R3	1
NM_014106	ZNF770	1
NM_017460	CYP3A4	1

---

Immunostimulatory motif search results

UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).

---

---

Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

Parameter	Spec. Score cut-off	Colour	Comment
Hit to same gene		Colour	Hits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit	≥80	Colour	Hits are very likely to cause an off-target effect
Medium scoring hit	<80¸≥40	Colour	Hits with a small chance of causing an off target effect.
Low scoring hit		Colour	Hits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-off	Colour
Match	Colour
Wobble base pairs (G-U)	Colour
Critical bases (none)	Colour
0.6 bits	Colour
0.4 bits	Colour
0.2 bits	Colour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer

For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317